Clinical trials: Unilateral Cleft Lip
Unilateral Cleft Lip and Palate, Cleft Lip
Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate Patients
The purpose of this study is to evaluate which surgical protocol for treating Unilateral Cleft Lip and Palate (UCLP), a single or two stage repair ( with hard palate late closure) will have less impact in mid facial growth.
- Conditions
- Unilateral Cleft Lip and Palate, Cleft Lip, Cleft Palate, Developmental Disabilities
- Trial name
- NCT02329509
- Testing
- two stage palate surgical repair, One stage Palate Surgical repair
- Volunteers
- 64 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Unilateral Cleft Lip
Philtrum Reconstruction Using Autogenous Fat Injection Versus a Surgical Repair in Secondary Unilateral Cleft Lip Revision
Two groups of patients with repaired unilateral cleft lip deformity having mild to moderate grooving and/or scarring of the philtral column and requiring a secondary cleft lip repair.
- Trial name
- NCT04735237
- Testing
- Autogenous fat injection, Surgical revision with orbicularis oris muscle reconstruction.
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Lip and Palate
Parent's Satisfaction and Evaluation of Postsurgical Outcomes in Unilateral Cleft Lip / Palate Newly Born Infants With / Without Vacuum Formed Nasoalveolar Molding Aligners : A Controlled Clinical Trial
Newborns with unilateral cleft lip/ palate will be treated pre-surgically by Vacuum formed aligners in order to evaluate its effect on Nasoalveolar complex.
- Trial name
- NCT03011489
- Testing
- Vacuum formed aligners
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Unilateral Cleft Lip
Comparison of Techniques in Repair of Unilateral Cleft Lip
Over the past century, there have been major advances in unilateral cleft-lip repair techniques toward the method's modern form.
- Trial name
- NCT05080855
- Testing
- modified Millard technique vs Tennison-Randall technique
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Cleft Lip
Orbicularis Oris Z-plasty Modification of Modified Millard Technique and the Esthetic Outcome of Cleft Lip Repair
This study aimed to evaluate the effect of orbicularis oris muscle z-plasty modification of modified Millard technique on the esthetic outcome and length of the repaired lip
- Trial name
- NCT04627389
- Testing
- orbicularis oris muscle Z- plasty modification of modified millard technique, modified millard technique
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fayoum University
Cleft Lip Palate, Cleft Lip, Unilateral, Complete
Nasoalveolar Molding for Egyptian Cleft Lip Palate Infants
The cleft lip and palate (CLP) is the commonest craniofacial anomaly worldwide. Nasoalveolar molding (NAM) therapy has emerged in the management of CLP as an early presurgical intervention to provide symmetry to severely deformed…
- Trial name
- EgyCleft (NCT03029195)
- Testing
- Nasoalveolar molding therapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Unilateral Cleft Lip, Nasoalveolar Molding
Nasolabial Soft Tissue Esthetics and Maxillary Changes in Unilateral Cleft Lip and Palate Using PreSurgical Infant Orthopedics With Different Approaches
The nasal deformity is an abnormality in the appearance and structure of the nose in cleft patients having unilateral cleft lip and palate (UCLP).
- Trial name
- PSIO (NCT05940389)
- Testing
- Naso Alveolar Mold, Taping with nasal elevator:
- Volunteers
- 24 people
- Sponsor
- Al-Azhar University
Cleft Lip and Palate
Effectiveness of Nasal-alar Elevator Combined With Taping Vs. Taping Alone on Improving the Nose Esthetics and Maxillary Arch Dimensions in Infants With Unilateral Complete Cleft Lip and Palate
This randomized trial is designed to assess the effectiveness of nasal elevator as a presurgical infant orthopedics on improvement of nose esthetics vs taping alone.
- Trial name
- NCT04331379
- Testing
- Nasal Elevator, Taping Alone
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Surgically Repaired Unilateral Cleft Lip and Palate
Evaluation of Arch Dimensions of Children With Surgically Repaired Unilateral Cleft Lip and Palate
The aim of the study is to assess arch dimensions among children with surgically repaired unilateral cleft lip and palate.
- Trial name
- NCT03219021
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Menna Allah Mohammed Awad
Cleft Lip, Cleft Palate
Cleft Palate Surgery and Speech Development
Compare the outcome of two primary surgeries techniques (von Langenbeck and Furlow double z-plasty) performed on children with cleft lip/palate to determine if one results in significantly better velopharyngeal competency for…
- Trial name
- NCT00004639
- Testing
- Furlow double z-plasty palatoplasty palate repair, Von Langenbeck palatoplasty palate repair
- Where
- 2 sites in United States, Brazil
- Volunteers
- 475 people
- Sponsor
- University of Florida
Patients With Unilateral Cleft Lip With or Without Cleft Palate
A Proposal for a New Classification of Secondary Cleft Lip and Nose Deformities in Repaired Unilateral Cleft Lip
Congenital cleft lip with or without cleft palate is one of the most common congenital malformations with an estimated incidence of about 1 every 500 to 700 live births.
- Trial name
- NCT04972370
- Testing
- Patients with Unilateral Cleft Lip with or without Cleft Palate
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cleft Lip, Unilateral
Comparative Study Between Millard and Tennison Randall Techniques in Complete and Incomplete Cleft Lip Repair.
"the investigators will compare the quantitative and qualitative (functional and aesthetic outcomes) of these two surgical approaches for repair of the unilateral cleft lip using an evaluation protocol developed many years ago by…
- Trial name
- NCT06166238
- Testing
- Millard and Tension Randal Technique
- Volunteers
- 30 people
- Sponsor
- Assiut University
Cleft Lip and Palate
Unilateral Cleft Repair in One Surgery With Pure Primary Healing
Retrospective analysis of the current surgical method to repair unilateral cleft lip and palate malformations at our centre
- Trial name
- NCT04108416
- Testing
- Cleft lip and palate repair
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- University Hospital, Basel, Switzerland
Esthetic Outcome of Injection of Botulinum Toxin Type-A in Cleft Lip Repair
Evaluation of the Effect of Botulinum Toxin Type-A Injection Prior to Surgical Correction of Complete Unilateral Cleft Lip Repair by Modified Millard Cheiloplasty
Evaluation of the effect of botulinum toxin type-A injection prior to surgical correction of complete unilateral cleftlip repair by modified millard cheiloplasty
- Trial name
- NCT03047499
- Testing
- Botulinum toxin type A
- Where
- Egypt
- Volunteers
- 2 people
- Sponsor
- Mostafa Khairy
Unilateral Cleft Lip
The Effect of Use of Dermal Fat Graft as a Barrier Membrane
a study conducted to assess the use of dermal fat graft use as barrier membrane over grafted bone
- Trial name
- NCT05334602
- Testing
- Addition of dermal fat graft as protection over bone graft
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cleft Palate, Cleft Palate, Unilateral, Complete
MRI Assessment of Velopharyngeal Anatomy After Modified Furlow-Buccinator Flap in Late Primary Palate Repair
The goal of this case series study is to learn if magnetic resonance imaging (MRI) can show how well the palate and throat muscles work at rest and during speech after late cleft palate repair.
- Conditions
- Cleft Palate, Cleft Palate, Unilateral, Complete, Cleft Lip, Cleft Alveolus and Cleft Palate, Cleft Palate Repair
- Trial name
- NCT07514091
- Testing
- Modified Furlow Palatoplasty combined with buccinator myomucosal flap
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Unilateral Complete Cleft Lip and Palate
Printed Aligners for Nasoalveolar Molding Treatment
study will provide nasoalveolar molding (NAM) treatment, special care for infants born with cleft lip and palate. This novel appliance will help to provide the care in accurate and easy form by help of both digital work flow and…
- Trial name
- NAM (NCT06683560)
- Testing
- : photopolymer resin material "graphy" Tera Harz 85 will be used to print 3D printed aligners for NAM treatment
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Unilateral Cleft Lip
Using Customized Nasal Conformer in Correction of Cleft Nasal Deformity in Patients with Unilateral Cleft Lip
The goal of the study is to compare the cleft lip repair with and without the usage of customized milled nasal conformers in unilateral cleft lip patients on nostril size , alar cartilage and proportion of symmetry to the normal…
- Trial name
- NCT06637488
- Testing
- cleft lip repair using fisher technique
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Mahmoud Akram
Complete Unilateral Cleft Lip
Unilateral Cleft Lip Closure - Development of a New Hybrid Technique
Unilateral cleft lips can be treated with different incision techniques. According to a survey by the American Cleft Palate Association, the Millard II technique is currently used by the majority of US cleft surgeons.
- Trial name
- NCT05102513
- Testing
- Unilateral Cleft Lip Repair: Hybrid Technique, Unilateral Cleft Lip Repair: Millard 2 Technique
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Marco Kesting
Unilateral Complete Cleft Lip
Comparison of Two Nasoalveolar Molding Techniques in Complete Unilateral Cleft Lip Patient
Two types of Presurgical Nasoalveolar Molding (NAM) coexist in Craniofacial Center in Chang Gung Memorial Hospital. The objective of this study is to compare the number of clinical visits, total prices, complications and nasal…
- Trial name
- NAM (NCT01883726)
- Testing
- Grayson's presurgical nasoalveolar molding, Figueroa's presurgical nasoalveolar molding
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital