Clinical trials: Unilateral Headache
Short Lasting Unilateral Neuralgiform Headache Attacks
Phase 1b Study in Patients With Short-Lasting Unilateral Neuralgiform Headache Attacks (SUNHA)
This exploratory open-label phase 1b, ascending dose study is to evaluate the effects of psilocybin on cognition in patients with Chronic Short-Lasting Unilateral Neuralgiform Headache Attacks (SUNHA)
- Trial name
- NCT04905121
- Testing
- Psilocybin
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Beckley Psytech Limited
Migraine, Cluster Headache
Pain Biomarker Study
This study investigates molecular and physical biomarkers of headaches in order to better understand mechanisms of these diseases. There are 3 main parts: 1.
- Conditions
- Migraine, Cluster Headache, Trigeminal Autonomic Cephalgia, Hemicrania Continua
- Trial name
- PBS (NCT03511846)
- Testing
- Oral capsaicin, Topical capsaicin, Intranasal capsaicin
- Where
- United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Migraine, Hemicrania
Home Detox in Medication Overuse Headache (MOH) During Covid-19 Emergency
Medication Overuse Headache (MOH) is a disabling condition that affects the 2% of migraine population. Medication overuse (MO) makes this condition very difficult to treat.
- Trial name
- MOHC (NCT04410536)
- Testing
- Symptomatic drugs, Bridge therapy, Mindfulness program
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Craniofacial Pain, Migraine
Clinical Trial of Endoscopically Guided Injection of Exparel (Bupivacaine) for the Treatment of Craniofacial Pain
Exparel has a proven efficacy in providing pain relief for up to 72 hours with a single-dose administration at surgical sites. The study aims to evaluate the effectiveness of endoscopically-guided injection of Exparel…
- Conditions
- Craniofacial Pain, Migraine, Cluster Headache, Trigeminal Autonomic Cephalgia
- Trial name
- NCT04930887
- Testing
- Exparel (Bupivacaine Liposome), Saline
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stanford University
Chronic Migraine, Headache
The Efficacy Of Lidocaine Infusion IN Chronic Unilateral Migraine Headache
STUDY THE EFFICACY OF INTRAVENOUS LIDOCAINE INFUSION ON PATIENTS WITH CHRONICUNILATERAL MIGRAINE HEADACHE ..NO OF PATIENTS 80..WILLBE DIVIDED INTO 2 GROUPS..FIRST WILL RECEIVE MEDICAL TREATMENT PLUS LIDOCAINE INFUSION ONCE WEEKLY…
- Trial name
- NCT06109389
- Testing
- Lidocaine IV
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Migraine Without Aura, Unilateral Headache
Acupuncture for Migraine Prophylaxis
Hypothesis: Acupuncture obtains an abiding effect on migraine prophylaxis Design: A open-label randomized controlled trial. 249 participants will be included.
- Trial name
- AMP (NCT01687660)
- Testing
- acupuncture
- Where
- China
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Li ying
Migraine
Rizatriptan in Acute Treatment of Migraine in Patients With Unilateral Trigeminal-autonomic Symptoms.
Triptans are first choice drugs in the acute treatment of migraine and cluster headache. However, while in cluster headache the response rate to subcutaneous sumatriptan is 96%, around 30% of patients fail to respond to a…
- Trial name
- NCT00753311
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS San Raffaele
Migraine, Greater Occipital Nerve Pulsed Radiofrequency, Headache Disorders
Comparing Unilateral and Bilateral Proximal GONPRF in Migraine Treatment
This study is designed to compare the clinical effectiveness of unilateral and bilateral Greater Occipital Nerve Pulsed Radiofrequency (GON-PRF) treatment at the C2 level in patients with migraine.
- Conditions
- Migraine, Greater Occipital Nerve Pulsed Radiofrequency, Headache Disorders, Ultrasound Guided Nerve Block
- Trial name
- (UBGON-PRF) (NCT06894121)
- Testing
- Greater Occipital Nerve Pulsed Radiofrequency (Unilateral), Bilateral GON PRF Treatment:
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people
- Sponsor
- Ankara City Hospital Bilkent
Cervicogenic Headache
Effects of Shi Style Cervical Mobilization Versus SNAGS in Patients With Cervicogenic Headache
Cervicogenic headache (CGH) manifests as unilateral neck pain referred from the neck's soft tissues or bony structures. The aim of this study will be to compare the effectiveness of Shi style cervical mobilization versus…
- Trial name
- NCT06459726
- Testing
- shi style mobilization, SNAGS
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hemicrania Continua
Erenumab For Treatment of Hemicrania Continua
This research is being conducting to learn if the study drug erenumab is successful in treating hemicrania continua. The study is also evaluating the safety and tolerability of erenumab in individuals being treated for hemicrania…
- Trial name
- NCT04303845
- Testing
- Erenumab
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Cervicogenic Headache
Specific Neck Rehabilitation for Unilateral Headache and Neck Pain, and Structural and Functional Changes in the Brain
In part 1 of the project clinical effect of specific neck rehabilitation for unilateral headache and neck pain (also termed cervicogenic headache) will be compared with standard primary health care.
- Trial name
- NCT02908984
- Testing
- Specific neck rehabilitation, Standard primary health care
- Where
- Norway
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Migraine, Chronic Tension-Type Headache
Nurse Intervention Trial
This randomized open-label prospective study focus on headache patients initiating preventive treatment, where the treating physician identifies a need for follow-up visits in specialized healthcare.
- Conditions
- Migraine, Chronic Tension-Type Headache, Cluster Headache, Hemicrania Continua
- Trial name
- NCT06200480
- Testing
- Telephone by nurse
- Where
- Norway
- Volunteers
- 147 people
- Sponsor
- Norwegian University of Science and Technology
Cluster Headache, Cluster Headaches and Other Trigeminal Autonomic Cephalgias
The Will Erwin Headache Research Center - Cluster Headache Study
The Will Erwin Headache Research Center Study of Cluster Headache and Trigeminal Neuralgia is a prospective, multicenter, observational research network for subjects with Cluster Headache and/or Trigeminal Neuralgia.
- Conditions
- Cluster Headache, Cluster Headaches and Other Trigeminal Autonomic Cephalgias, Paroxysmal Hemicrania, SUNCT
- Trial name
- WEC1 (NCT02910323)
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Trigeminal Autonomic Cephalalgias, Cluster Headache
Italian Trigeminal Autonomic Cephalalgias Assessment Study
ITACA is a prospective, multicenter, observational longitudinal cohort study conducted in routine clinical practice at six Italian headache centers.
- Conditions
- Trigeminal Autonomic Cephalalgias, Cluster Headache, Paroxysmal Hemicrania, SUNCT
- Trial name
- ITACA (NCT07812740)
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Migraine
Study of Quality of Life in Subjects With Chronic or High-frequency Episodic Migraine and Associated Comorbidities Treated With Erenumab
Migraine is a very common, neurological disorder, characterized by recurrent episodes of headache, potential progression to more frequent and severe attack patterns, and associated symptoms.
- Trial name
- COMIG (NCT04114630)
- Testing
- erenumab 70mg/mL
- Where
- 27 sites in Spain
- Sponsor
- Novartis Pharmaceuticals
Unilateral Headache, Musculoskeletal Neck Pain
Effects of Cervical Manual Therapy on Cervicogenic Headache
The effects of cervical spine manual therapy, including mobilization and manipulation, on cervical spine range of motion, joint position sense, and balance is unknown among individuals with cervicogenic headache.
- Trial name
- NCT03385889
- Testing
- Cervical Spine Mobilization, Cervical Spine Manipulation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Shenandoah University