Clinical trials: Unprotected Sex
Substance Use, Unprotected Sex
Intervention for Substance Use and Sexual Risk Behavior in Homeless Youth
This study will evaluate a program called AWARE, which is a voluntary four session group-based motivational interviewing (MI) intervention to reduce substance use and sexual risk behavior among 18-25 year olds who are…
- Trial name
- NCT03735784
- Testing
- AWARE
- Where
- 3 sites in United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- RAND
Sexual Behavior, Unprotected Sex
Evaluation of Manhood 2.0: A Community-Based Teen Pregnancy Prevention Program for Young Men
Manhood 2.0 is a male-only group-level intervention, delivered over 13 hours, based on social cognitive theory, social norm theory, theory of gender and power, and the theory of reasoned action.
- Trial name
- NCT04962802
- Testing
- Manhood 2.0, Post-High School Readiness
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Child Trends
Sex, Unsafe, Drug Use
Addressing Substance Use Through CVCT
The proposed study developed and tested two adjunct components for use in Couples HIV Testing and Counseling (CHTC) with gay-male couples: a communication skills training video and a substance use agreement module.
- Trial name
- NCT03125915
- Testing
- Communication skills training video, substance use module, Couples HIV Testing and Counseling
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
Condomless Sex, Sexual Assault
Evaluating a Digital Intervention to Improve Adolescent Condom Use and Communication
The purpose of this study is to test the effectiveness, likability, and implementation potential of PACT, an adapted digital program to teach non-heterosexual adolescent boys about sexual consent and condom negotiation in a…
- Trial name
- NCT06878755
- Testing
- Promoting Assertive Communication among Teens (PACT), Healthy Minds
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- North Carolina Agriculture & Technical State University
Condomless Sex, Human Immunodeficiency Virus (HIV)
Cape Town Young Women's Health CoOp
This two-arm cluster randomized trial tested a gender-focused comprehensive HIV testing and counselling (HTC) program, the Young Women's Health CoOp (YWHC) with a standard HTC program and targeted female adolescents (aged 16-19)…
- Conditions
- Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infections (STIs), Alcohol and Drug Use
- Trial name
- NCT02974998
- Testing
- Young Women's Health CoOp (YWHC), Standard HTC
- Where
- South Africa
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RTI International
Help-Seeking Behavior, Pre-exposure Prophylaxis Use
Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)
The goal of this quasi-experimental, community intervention is to reduce HIV sexual risk among Latino immigrant bisexual men or men who have sex with men.
- Conditions
- Help-Seeking Behavior, Pre-exposure Prophylaxis Use, Condomless Sex, Risky Health Behavior
- Trial name
- NCT07475702
- Testing
- Moon and Sun Brothers: A Community Prevention Intervention
- Where
- 2 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- San Francisco State University
Unsafe Sex
Construction of a Risky Sexual Behaviour Intervention Programme for College Students Based on BCW Theory
Using the intervention functions of Behavior Change Wheel (BCW) and BCTs, we constructed an intervention program for college students' risky sexual behaviors by combining literature analysis, qualitative research, Delphi's expert…
- Trial name
- NCT06435234
- Testing
- risky sexual behavior intervention
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rong Zhang
HIV
A Couple-Based Relationship Strengthening HIV Intervention for Young Parents
This study seeks to develop, implement, and assess an innovative 15-session couple-based intervention to be delivered in a group format to young parents that aims to strengthen relationships and reduce HIV risk.
- Trial name
- NCT01643005
- Testing
- Relationship Strengthening HIV Prevention Intervention, Parenting Program Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV Infections, Sexual Risk Behavior
Positive Choice: Prevention for Positive Health
This is a randomized, controlled trial of Positive Choice, an interactive multimedia computer program, to determine whether it can detect and reduce risky behaviors among HIV-positive adults.
- Conditions
- HIV Infections, Sexual Risk Behavior, Substance Use Risks
- Trial name
- NCT00447707
- Testing
- Positive Choice
- Where
- 5 sites in United States
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
HIV Infections
A Network Intervention for Reducing Sexual Risk for HIV With African American Men Who Have Sex With Men (AA MSM)
The purpose of the study is to examine the efficacy of a network-oriented "outreach intervention" to reduce HIV and sexually transmitted infection (STI) related risk behaviors among African American men who have sex with men (AA…
- Trial name
- UDP (NCT00691041)
- Testing
- Unity in Diversity
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Alcohol; Harmful Use, Sex, Unsafe
MI With Text Messaging to Reduce Sexual Risk and Hazardous Drinking Among MSM
This is a small pilot study to provide effect size estimates for a brief intervention designed to reduce hazardous drinking and sexual risk behavior among men who have sex with men.
- Trial name
- MI&TXT4MSM (NCT03755661)
- Testing
- MI&TXT4MSM
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Sexually Transmitted Diseases, Unsafe Sex
Protect and Connect: Couple HIV Prevention for Drug Involved Male Offenders
This study is a randomized controlled trial (RCT) that will rigorously evaluate the implementation, effectiveness and cost-effectiveness of a couple-based integrated human immunodeficiency virus (HIV) and drug abuse prevention…
- Conditions
- Sexually Transmitted Diseases, Unsafe Sex, Substance-Related Disorders
- Trial name
- PACT (NCT01690494)
- Testing
- PACT, TAU
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Columbia University
Binge Alcohol Consumption, Risk Behavior, Health
A Family-Based Alcohol Preventive Intervention for Latino Emerging Adults
The purpose of the proposed study was to develop a family-based drinking prevention intervention for Latino emerging adults (EAs) and Latino parents of EAs.
- Conditions
- Binge Alcohol Consumption, Risk Behavior, Health, Driving Under the Influence, High-Risk Sex
- Trial name
- LEA (NCT05437081)
- Testing
- Latino Emerging Adults (LEA)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Economic Hardship, Condomless Sex
Education and Employment Support for HIV Prevention in Young Adults (ENSPIRE)
The study team will conduct a two-group study to examine the efficacy of implementing a combination intervention to improve economic stability and HIV preventive behaviors. The team will enroll approximately 500 young adults.
- Conditions
- Economic Hardship, Condomless Sex, Utilization, Health Care
- Trial name
- ENSPIRE (NCT06096324)
- Testing
- Job announcements plus HIV prevention text messages, educational sessions, economic resources, and mentoring., Job announcements
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Depression, Anxiety, Alcohol Abuse
Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach
Background: LGB people experience a large number of anxiety and mood disorders, and risk behaviors than heterosexual (Marshall et al., 2011).
- Conditions
- Depression, Anxiety, Alcohol Abuse, Sexual Compulsivity, Unsafe Sex
- Trial name
- NCT03980873
- Testing
- ESTEEM (Effective Sikills to Empower Effective Men)
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
PSA, Unprotected Sex
Promoting CSD500 Use Among Women in Established Relationships
Globally, women in established relationships remain at risk for unintended pregnancy and sexually transmitted infections (STIs), including HIV.
- Trial name
- NCT02934620
- Testing
- CSD500 Condom, Standard Condom, Condom Counseling
- Where
- Vietnam
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Ohio State University
HIV Infections
Project ICARE: Intervening for Community Awareness, Respect, & Empowerment
This project will test the efficacy of a behavioral intervention to reduce sexual risk for HIV infection among African American Men who Have Sex with Men (MSM).
- Trial name
- NCT00712088
- Testing
- Project ICARE, HCT
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Unsafe Sex, Risk Reduction
Project Power: An HIV Risk Reduction Intervention for Black Men Who Have Sex With Men and Women (BMSM/W)
The goal of this study is to develop and test a program to help Black men who have sex with men and women reduce their chances of getting or giving HIV infection to their sex partners.
- Trial name
- Power (NCT01376895)
- Testing
- PROJECT POWER, Power Health
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Unsafe Sex
MyLife MyStyle Evaluation Project
The purpose of the MyLife MyStyle Evaluation Project is to determine whether the MyLife MyStyle group-level intervention reduces HIV sexual-risk behaviors among 18- to 29-year-old African American men who have sex with men (MSM).
- Trial name
- MLMS (NCT01640392)
- Testing
- MyLife MyStyle group-level intervention
- Where
- United States
- Volunteers
- 528 people, healthy volunteers welcome
- Sponsor
- Los Angeles County Department of Public Health
Condomless Sex, Human Immunodeficiency Virus (HIV)
NC Young Women's CoOp
This three-arm cross-over randomized trial will develop, test, and compare the efficacy of two delivery formats of the Young Women's CoOp (YWC), which is designed to provide risk reduction and empowerment skills, as well as…
- Conditions
- Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infection (STI), Alcohol and Drug Use
- Trial name
- NCT02965014
- Testing
- Face-to-Face Young Women's CoOp (YWC), mHealth Young Women's CoOp (YWC), HIV Counseling and Testing
- Where
- 4 sites in United States
- Volunteers
- 652 people, healthy volunteers welcome
- Sponsor
- RTI International