Clinical trials: Unsedated
Colonoscopy, Unsedated
Factors Associated With Pain During Unsedated Colonoscopy
Colonoscopy is the gold standard in the diagnosis and treatment colorectal disease, but due to the uncomfortable or even painful procedure, a part of people unwilling to undergoing the examination and giving analgesic agents were…
- Conditions
- Colonoscopy, Unsedated, Pain
- Trial name
- NCT03420612
- Where
- China
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Application Site Discomfort
Clinical Trial With Bupivacaine Lozenges as Local Anaesthesia Under Upper Gastrointestinal Endoscopy
In this project the investigators want to compare a new anaesthetic method during upper gastroscopic endoscopy, compared to the traditional used method in a private clinic.
- Trial name
- NCT01832675
- Testing
- Xylocain, cutaneous spray, solution, Bupivacaine lozenge
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Ove Andersen
Pain
TENS Efficacy in Pain Relief During Hysteroscopy
Pain Relief During Unsedated Office Hysteroscopy by Applying Transcutaneous Electrical Nerve Stimulation : Randomized controlled trial
- Trial name
- NCT04229576
- Testing
- TENs
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Adenoma, Pain
Water Method in Elder Patients With Unsedated Colonoscopy
Water method with water exchange has been shown to reduce medication requirement and pain experienced during colonoscopy. It increases the success rate of cecal intubation in sedated and unsedated patients undergoing screening…
- Trial name
- NCT01546220
- Testing
- Water colonoscopy
- Where
- China
- Sponsor
- Air Force Military Medical University, China
Polyps
Carbon Dioxide During Screening Unsedated Colonoscopy
Colonoscopy is currently most effective procedure used for detecting colon cancer especially in the early stages. Screening colonoscopies are performed in the symptom-free patients at risk of familial colon cancer.
- Trial name
- NCT01461564
- Testing
- Colonoscopy
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jagiellonian University
Colon Disease;, Rectal Disease
Ultrafine Endoscope for Colonoscopy in Diagnosis of Colorectal Diseases
This study is the evaluation of ultrafine endoscope (with small caliber and turning radius )for colonoscopy in decreasing abdominal pain of patients . 60 patients will be accepted in this trial.
- Trial name
- NCT02160210
- Testing
- Ultrafine Endoscope
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Youlin Yang ,MD
Adenoma, Pain
Water Method in Low-body Mass Index (BMI) Female Patients With Unsedated Colonoscopy
Water method with water exchange has been shown to reduce medication requirement and pain experienced during colonoscopy. It increases the success rate of cecal intubation in sedated and unsedated patients undergoing screening…
- Trial name
- NCT01546259
- Testing
- Water colonoscopy
- Where
- China
- Sponsor
- Air Force Military Medical University, China
Colonoscopy Pain
Pre-procedural Risk Score-Based Endoscopist Assignment for Pain Reduction in Unsedated Colonoscopy
This multicenter randomized controlled trial evaluates whether a pre-procedural risk score-based endoscopist assignment strategy reduces intraprocedural pain in high-risk patients undergoing unsedated colonoscopy.
- Trial name
- NCT07713953
- Testing
- Risk Score-Based Endoscopist Assignment
- Where
- China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ningbo No. 1 Hospital
Colonoscopy
Warm Water for Unsedated Colonoscopy
Unsedated colonoscopy is characterized by lower costs, recovery time and incidence of drug-related side effects, although it may be painful for the patient.
- Trial name
- WW (NCT00905554)
- Testing
- warm water irrigation, air insufflation
- Where
- Italy
- Volunteers
- 230 people
- Sponsor
- Valduce Hospital
Pain, Colorectal Adenomas
A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in CRC Screening
Water-aided method for colonoscopy can be broadly subdivided into two major categories. Water Immersion (WI), characterized by suction removal of the infused water predominantly during the withdrawal phase of colonoscopy, and…
- Conditions
- Pain, Colorectal Adenomas, Colorectal Cancer
- Trial name
- NCT01780818
- Testing
- Air Insufflation method., Water Immersion method., Water Exchange method.
- Where
- 3 sites in United States, Italy
- Volunteers
- 288 people
- Sponsor
- Presidio Ospedaliero Santa Barbara
Outpatients
The Optimal Timing of Carbon Dioxide Insufflation During Colonoscopy in Unsedated Patients
Insufflation of carbon dioxide (CO2) instead of air can reduce pain resulting from colon distension after colonoscopy because CO2 is rapidly absorbed from the colon and excreted through the lungs.
- Trial name
- NCT01415076
- Testing
- Insufflation with CO2
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Cecal Intubation Success Rate
Disposable Sheathed Gastroscopic System for Cecal Intubation
A novel disposable sheathed gastroscope system has been shown to be safe and more efficient in clinical practice during gastroscopy.
- Trial name
- NCT02495480
- Testing
- A novel disposable sheath
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yuqi He
Esophagogastroduodenoscopy, Upper Gastrointestinal Bleeding (UGIB)
Effect of Ondansetron on Patient Tolerance, Efficacy and Endoscopist Workload in Unsedated Endoscopy for Upper Gastrointestinal Bleeding
The goal of this clinical trial is to evaluate whether intravenous ondansetron can improve patient tolerance and reduce discomfort during unsedated emergency esophagogastroduodenoscopy (EGD).
- Trial name
- NCT07336680
- Testing
- intravenous ondansetron
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking Union Medical College Hospital
Gastrointestinal Diseases, Digestive System Diseases
Warm Water and Unsedated Colonoscopy
Unsedated or slightly sedated colonoscopy has fast recovery time, less cost and lower or no incidence of drug-related side effects. May be slightly painful or discomforting for the patient.
- Trial name
- WW (NCT01463319)
- Testing
- air insufflation, warm water irrigation
- Where
- 2 sites in Italy
- Volunteers
- 818 people, healthy volunteers welcome
- Sponsor
- Presidio Ospedaliero Santa Barbara
Esophagogastroduodenoscopy
Meperidine as the Single Sedative Agent During Esophagogastroduodenoscopy
Upper endoscopy is uncomfortable for most patients. Meperidine has both sedative and analgesic effects, so its use may be helpful for patients receiving upper endoscopy.
- Trial name
- NCT01547520
- Testing
- Meperidine, normal saline
- Where
- Taiwan
- Volunteers
- 140 people
- Sponsor
- Dalin Tzu Chi General Hospital
Intubation, Surgery
Water Method Colonoscopy in Patients With Prior Surgery
Water method with water exchange has been shown to reduce medication requirement and pain experienced during colonoscopy. It increases the success rate of cecal intubation in sedated and unsedated patients undergoing screening…
- Conditions
- Intubation, Surgery, Adenoma, Pain
- Trial name
- NCT01485133
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Air Force Military Medical University, China
Satisfaction
Patient Satisfaction With Sedated vs. Unsedated Colonoscopy
This is a prospective, observational study to evaluate patient satisfaction with colonoscopy, depending on whether sedation is used during the procedure or not.
- Trial name
- NCT02770742
- Where
- Germany
- Volunteers
- 1,070 people
- Sponsor
- Helios Research Center
Chronic Illness, Hematologic Malignancy
Distracting Through Procedural Pain and Distress
Children with acute and chronic illness undergo frequent, painful, and distressing procedures. This randomized control trial was used to evaluate the effectiveness of guided imagery (GI) vs virtual reality (VR) on the procedural…
- Conditions
- Chronic Illness, Hematologic Malignancy, Bone Marrow Transplant Infection, Oncology
- Trial name
- NCT04892160
- Testing
- Guided Imagery, Virtual Reality
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- Medical College of Wisconsin
Failed or Difficult Intubation, Adenoma
Water Method in Patients With Incomplete Colonoscopy
Water method with water exchange has been shown to reduce medication requirement and pain experienced during colonoscopy. It increases the success rate of cecal intubation in sedated and unsedated patients undergoing screening…
- Conditions
- Failed or Difficult Intubation, Adenoma, Pain
- Trial name
- NCT01546246
- Testing
- Water colonoscopy
- Where
- China
- Sponsor
- Air Force Military Medical University, China
Pain, Colorectal Adenomas
Comparison of Methods to Distend the Colon During Insertion: CO2, Air Insufflation, Water-aided Colonoscopy
Insufflation of the colon, usually with room air, is necessary to distend the lumen for exploration. Carbon dioxide (CO2) insufflation instead of room air insufflation (AI) has been shown to decrease symptoms of abdominal pain or…
- Conditions
- Pain, Colorectal Adenomas, Colorectal Cancer
- Trial name
- NCT01954862
- Testing
- Air Insufflation method., CO2 insufflation, Water Immersion/CO2
- Where
- 3 sites in United States, Czechia and 1 more
- Volunteers
- 624 people
- Sponsor
- Presidio Ospedaliero Santa Barbara