Clinical trials: Unspecified Adult Solid Tumor, Protocol Specific, completed
Recurrent Colon Cancer, Recurrent Rectal Cancer
GTI-2040, Oxaliplatin, and Capecitabine in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer or Other Solid Tumors
This phase I trial is studying the side effects and best dose of capecitabine when given together with GTI-2040 and oxaliplatin in treating patients with locally advanced or metastatic colorectal cancer or other solid tumors.
- Conditions
- Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IIIC Colon Cancer, Stage IIIC Rectal Cancer
- Trial name
- NCT00084643
- Testing
- GTI-2040, oxaliplatin, capecitabine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Cancer Institute (NCI)
Unspecified Adult Solid Tumor, Protocol Specific
Octreotide and Doxorubicin in Treating Patients With Advanced Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Octreotide may help doxorubicin kill more cancer cells by making tumor cells more sensitive to the drug.
- Trial name
- NCT00008073
- Testing
- doxorubicin hydrochloride, octreotide acetate
- Where
- United States
- Sponsor
- University of Pittsburgh
Unspecified Adult Solid Tumor, Protocol Specific
Irinotecan in Treating Patients With Advanced Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of irinotecan in treating patients who have advanced solid…
- Trial name
- NCT00004051
- Testing
- irinotecan hydrochloride
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Nausea and Vomiting, Unspecified Adult Solid Tumor, Protocol Specific
UMCCOP 02-01 Ginger in Treating Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer
RATIONALE: The herb ginger may help to reduce or prevent nausea and vomiting in patients receiving chemotherapy for cancer. PURPOSE: This randomized phase II trial is studying how well ginger works in reducing or preventing…
- Trial name
- IRB 2003-551 (NCT00064272)
- Testing
- ginger extract
- Where
- 6 sites in United States, Puerto Rico
- Volunteers
- 180 people
- Sponsor
- University of Michigan Rogel Cancer Center
Metastatic Cancer, Pain
Morphine After Radiofrequency Ablation of Painful Bone Metastases in Patients With Cancer
RATIONALE: Morphine may reduce pain in patients who have undergone radiofrequency ablation to remove bone metastases. PURPOSE: This phase II trial is studying how well morphine works after radiofrequency ablation of painful bone…
- Conditions
- Metastatic Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- MEDOR (NCT00712712)
- Testing
- Acetaminophen, Morphine Sulfate, Questionnaire administration
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Institut Bergonié
Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific
Arsenic Trioxide in Treating Patients With Advanced Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of arsenic trioxide in treating patients who have advanced…
- Trial name
- NCT00003630
- Testing
- arsenic trioxide
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Constipation, Impaction, and Bowel Obstruction, Unspecified Adult Solid Tumor, Protocol Specific
S1316, Surgery or Non-Surgical Management in Treating Patients With Intra-Abdominal Cancer and Bowel Obstruction
This partially randomized clinical trial studies surgery or non-surgical management in treating patients with intra-abdominal cancer and bowel obstruction.
- Trial name
- NCT02270450
- Testing
- therapeutic conventional surgery, gastrointestinal complications management/prevention, quality-of-life assessment
- Where
- 38 sites in United States, Canada and 3 more
- Volunteers
- 221 people
- Sponsor
- SWOG Cancer Research Network
Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
Modafinil in Treating Fatigue in Patients Receiving Chemotherapy for Cancer
RATIONALE: Modafinil may be effective in relieving fatigue in patients with cancer who are undergoing chemotherapy. The effectiveness of modafinil in relieving chemotherapy-related fatigue is not yet known.
- Trial name
- NCT00042848
- Testing
- modafinil
- Where
- 35 sites in United States
- Volunteers
- 837 people
- Sponsor
- Gary Morrow
Unspecified Adult Solid Tumor, Protocol Specific
Docetaxel and Oxaliplatin in Treating Patients With Metastatic or Recurrent Solid Tumor
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00004243
- Testing
- docetaxel, oxaliplatin
- Where
- 3 sites in United States
- Sponsor
- City of Hope Medical Center
Unspecified Adult Solid Tumor, Protocol Specific
Safety Study of Increasing Doses of CKD-516 in Patients With Advanced Solid Cancers
A phase I study is conducted to determine the maximum tolerated dose (MTD), dose limiting toxicity (DLT), safety and pharmacokinetics (PK) profile of a single agent CKD-516 injection on twice-weekly schedule in patients with…
- Trial name
- NCT01560325
- Testing
- CKD-516 inj.
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Unspecified Adult Solid Tumor, Protocol Specific
Paricalcitol and Gemcitabine in Treating Patients With Advanced Cancer
RATIONALE: Paricalcitol may cause cancer cells to look more like normal cells, and to grow and spread more slowly. Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of cancer cells, either…
- Trial name
- NCT00217477
- Testing
- gemcitabine hydrochloride, paricalcitol
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Roswell Park Cancer Institute
Cervical Cancer, Colorectal Cancer
Octreotide in Preventing Diarrhea in Patients Who Are Undergoing Radiation Therapy to the Pelvis
RATIONALE: Octreotide may be effective in preventing or controlling diarrhea in patients who are undergoing radiation therapy to the pelvis. It is not yet known whether octreotide is effective for diarrhea.
- Conditions
- Cervical Cancer, Colorectal Cancer, Diarrhea, Endometrial Cancer
- Trial name
- NCT00033605
- Testing
- octreotide acetate, radiation
- Volunteers
- 130 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Pain, Unspecified Adult Solid Tumor, Protocol Specific
Improving Pain Management in Patients With Nonhematologic Cancer
RATIONALE: A pain assessment and management system for people with cancer may help doctors accurately assess and plan more effective pain treatment for patients who have cancer.
- Trial name
- NCT00036829
- Testing
- pain therapy
- Where
- United States
- Sponsor
- Inflexxion, Inc.
Psychosocial Effects of Cancer and Its Treatment, Unspecified Adult Solid Tumor, Protocol Specific
Evaluating Patient Participation in Phase I Clinical Trials
RATIONALE: Understanding why patients participate in a phase I clinical trial may help doctors plan better treatment for cancer.
- Trial name
- NCT00043030
- Testing
- psychosocial assessment and care
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Unspecified Adult Solid Tumor, Protocol Specific
Study to Assess Cancer Patients' Satisfaction With Hospital Quality of Care
RATIONALE: Questionnaires may help determine cancer patients' satisfaction with the quality of care they received in the hospital.
- Trial name
- NCT00045019
- Testing
- quality-of-life assessment
- Where
- 11 sites in Belgium, France and 3 more
- Volunteers
- 795 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Anemia, Fatigue
Epoetin Beta in Treating Fatigue and Anemia in Patients Receiving Palliative Care for Malignant Solid Tumors
RATIONALE: Epoetin beta may cause the body to make more red blood cells and may help relieve fatigue in patients with malignant solid tumors receiving palliative care.
- Conditions
- Anemia, Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00559195
- Testing
- epoetin beta, quality-of-life assessment
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospital Regional Universitaire de Limoges
Cancer, Psychological Stress
Stress Management Therapy in Patients Receiving Chemotherapy for Cancer
RATIONALE: A stress-management program may improve quality of life and reduce anxiety and depression in patients receiving chemotherapy for cancer.
- Conditions
- Cancer, Psychological Stress, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00377130
- Testing
- Self Administered Stress Management
- Where
- 51 sites in United States, Puerto Rico
- Volunteers
- 442 people
- Sponsor
- University of South Florida
Esophageal Cancer, Gastric Cancer
Edotecarin and Cisplatin in Treating Patients With Advanced or Metastatic Solid Tumors
RATIONALE: Drugs used in chemotherapy, such as edotecarin and cisplatin, use different ways to stop tumor cells from dividing so they stop growing or die. Combining edotecarin with cisplatin may kill more tumor cells.
- Conditions
- Esophageal Cancer, Gastric Cancer, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00072332
- Testing
- cisplatin, edotecarin
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Unspecified Adult Solid Tumor, Protocol Specific
Mistletoe Lectin in Treating Patients With Refractory Advanced Solid Tumors
RATIONALE: Mistletoe lectin may slow the growth of cancer cells and be an effective treatment for solid tumors. PURPOSE: Phase I trial to study the effectiveness of mistletoe lectin in treating patients who have refractory…
- Trial name
- NCT00006477
- Testing
- mistletoe extract
- Where
- 2 sites in Germany, Norway
- Volunteers
- 26 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Pulmonary Complications, Quality of Life
Theophylline in Treating Cancer Patients With Shortness of Breath
RATIONALE: Theophylline may help to relieve shortness of breath in patients who have cancer. It is not yet known whether theophylline is more effective than no further treatment for shortness of breath.
- Conditions
- Pulmonary Complications, Quality of Life, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00003684
- Testing
- theophylline, quality-of-life assessment
- Where
- 4 sites in Canada
- Volunteers
- 3 people
- Sponsor
- NCIC Clinical Trials Group