Clinical trials: Unstable Fracture
Distal Radius Fracture
Distal Radius Fractures in Patients Over 65 Years, Operation or Cast?
Eligible patients that sign an informed consent will be randomized to operation with volar locking plate or cast immobilization. Primary follow-up after 1 year.
- Trial name
- DROC (NCT02336035)
- Testing
- Volar plate
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Fracture Dislocation of Ankle Joint
A Prospective Randomized Pilot Study to Compare Open Versus Percutaneous Syndesmosis Repair of Unstable Ankle Fractures
This study evaluates fracture healing, anatomic reduction and return to functioning in patients with unstable Weber C type fractures of the ankle.
- Trial name
- ART (NCT02245893)
- Testing
- open reduction internal fixation (ORIF)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Ankle Fracture
Outcomes of Operative Treatment of Unstable Ankle Fracture - Comparison Between Metallic and Biodegradable Implants
The purposes of this study are to compare the outcomes of the biodegradable implants for the fixation of ankle fracture and those of metallic implants, and to assess the problems of the biodegradable implants.
- Trial name
- NCT01431560
- Testing
- fixation of the ankle fracture (Solco ), fixation of the ankle fracture (Freedom)
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- National Police Hospital
Ankle Fracture, Malleolus Fracture
Surgical Versus Nonsurgical Treatment of Fibular Fractures: A Prospective Randomized Study
Isolated surgical repair of the inside portion of the tibia may be enough to stabilize an ankle fracture in which both the tibia and the fibula are broken.
- Conditions
- Ankle Fracture, Malleolus Fracture, Medial Malleolus Fracture, Bimalleolar Fracture
- Trial name
- NCT02032966
- Testing
- Nonsurgical, Surgical
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Tennessee
Radius Fractures
Non-bridging Fixator Versus Percutaneous Pinning for Distal Radius Fractures
The treatment of extra-articular distal radius fractures is still controversial. In Canada, most patients with unstable fractures are treated with pinning and cast.
- Trial name
- NCT00908895
- Testing
- Radio-radial fixator, Percutaneous pinning
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Hopital de l'Enfant-Jesus
Ankle Fracture - Medial Malleolus
Medial Malleolus: Operative Or Non-operative
Medial malleolus: Operative Or Non-operative (MOON study) Ankle fractures are a common Orthopaedic trauma presentation, accounting for approximately 10% of the workload.
- Trial name
- MOON (NCT03362229)
- Testing
- Fixation, Non-fixation
- Where
- United Kingdom
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Royal Infirmary of Edinburgh
Unstable Fracture, Hip Fracture
MobiChina - A Prospective Multicenter Cohort Study
The study will assess the difference in functionality between early vs. standard mobilization after hip fracture in the Chinese population.
- Trial name
- NCT02296086
- Where
- 11 sites in China, Hong Kong
- Volunteers
- 284 people
- Sponsor
- AO Innovation Translation Center
Intertrochanteric Fractures
Efficacy and Safety of Cemented and Cementless Prostheses for Unstable Intertrochanteric Fractures in the Elderly
This trial explores the application of different hip replacement materials in elderly patients with unstable intertrochanteric fracture, and aims to provide the experience and basis for hip arthroplasty in elderly osteoporosis…
- Trial name
- NCT03193697
- Testing
- cemented SPII prosthesis, cementless Wagner prosthesis
- Volunteers
- 86 people
- Sponsor
- Harrison International Peace Hospital
Sacral Fracture
Comparison of Minimally Invasive Versus Open Spinopelvic Fixation for Unstable Sacral Fractures
The aim of this retrospective study is to evaluate patients with vertically unstable high-energy sacral fracture operated on at our institution with spinopelvic fixation, to compare the traditionally open method of fixation with…
- Trial name
- NCT06755580
- Testing
- spinopelvic fixation
- Where
- Slovakia
- Volunteers
- 51 people
- Sponsor
- F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica
Fractures of the Long Bones, Vertically Stable Pelvic Fractures
Observational Study for the Evaluation of the Clinical Performance and Safety Profile of the GALAXY FIXATION™ System and Orthofix Implantable Devices: GALAXY Study
The GALAXY FIXATIONTM System and Orthofix implantable devices study intends to evaluate the clinical performance and safety profile of the study medical/investigational devices in the standard clinical practice.
- Conditions
- Fractures of the Long Bones, Vertically Stable Pelvic Fractures, Vertically Unstable Pelvic Fractures
- Trial name
- NCT06690437
- Testing
- Galaxy Fixation System and Orthofix implantable devices
- Where
- 3 sites in Italy
- Volunteers
- 3 people
- Sponsor
- Orthofix s.r.l.
Trochanteric Fractures
Treatment Of Unstable Trochanteric Fracture: A Comparative Study Between DHS And DHS With Trochanteric Stabilization Plate
compare the results in treatment of unstable trochanteric fracture by using DHS and DHS with Trochanteric Stabilizing plate as regard shaft medialization.neck shaft angle measurment and shaft migration
- Trial name
- NCT05781815
- Testing
- dynamic hip screw
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Trimalleolar Ankle Fracture, Unstable Trimalleolar Ankle Fracture
Early Ambulation Safely in Unstable Ankle Fractures (EASY-Ankle)
This pilot randomized controlled trial will evaluate the safety and feasibility of beginning weight-bearing earlier after surgery for an unstable trimalleolar ankle fracture.
- Trial name
- EASY-Ankle (NCT07811804)
- Testing
- Postoperative Weight-Bearing Rehabilitation Protocol
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
Ankle Fractures, Surgery
Immediate Weight-Bearing Ankle Study
This single-centre historical control group comparative study will compare outcomes of surgically-treated rotational ankle fractures and the current routine practice of early protected weightbearing and range of motion with…
- Trial name
- NCT03032653
- Testing
- Late Rehabilitation, Early Rehabilitation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Fraser Orthopaedic Research Society
Hip Fracture
Influence of Static Distal Locking of a Short Proximal Femoral Nail
Prospective, comparative, randomized, double-blind study to evaluate the outcomes of trochanteric nailing in unstable hip fractures with and without a distal interlocking screw.
- Trial name
- NCT06357312
- Testing
- hip trochanteric nail
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Elda University Hospital
Trauma, Flail Chest
Operative Treatment of Unstable Thoracic Cage Injuries and Chest Wall Deformity in Trauma
The purpose of this prospective controlled study is to determine whether surgical management of unstable thoracic cage injuries and chest wall deformity in trauma reduces the need for and the time spent on ventilator compared to…
- Conditions
- Trauma, Flail Chest, Rib Fractures, Surgery
- Trial name
- NCT02132416
- Testing
- NSAID, Opioids, Thoracic Epidural anaesthesia
- Where
- 2 sites in Sweden
- Volunteers
- 92 people
- Sponsor
- Sahlgrenska University Hospital
Fracture of Hip
InterTAN: Integrated Dual Screw Design Improve Biomechanics/Function Following Fixation Surgery
The goal of this pilot, patient blinded randomized trial is to develop a mechanistic understanding of gait following fixation of unstable intertrochanteric hip fractures and return to function and pain control.
- Trial name
- NCT06024304
- Testing
- Synthes TFNA, Trigen InterTAN
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Paul E. Matuszewski
Ankle Fractures, Syndesmotic Injury
Biodegradable Magnesium Screws for Unstable Ankle Fracture Surgery
Ankle fractures are among the most common injuries that need surgery. When the broken bones make the ankle unstable, surgeons usually fix them with metal screws and plates.
- Trial name
- NCT07693933
- Testing
- RemeOs Magnesium-Based Biodegradable Screw
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Massachusetts General Hospital
Colles' Fracture, Radius Fractures
Operative Treatment of Extraarticular Colles' Fractures of the Distal Radius (OTEC)
This is a prospective, randomized, multi-center pilot study of unstable extraarticular fractures of the distal radius with dorsal displacement of the distal fragment in elderly patients.
- Trial name
- NCT00271726
- Testing
- Osteosynthesis with palmar locking plate, Osteosynthesis with external fixator, Osteosynthesis with Kirschner wires
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Unstable Sacral/Pelvic or Acetabular Fracture
A Comparison Study for Unstable Sacrum/Pelvis and Acetabular Fracture Treated With Open Reduction and Internal Fixation With Minimally Invasive Internal Fixation
Unstable sacral/pelvic or acetabular fracture are severe high energy fractures Surgical intervention are necessary after patient's conditions are stable.
- Trial name
- NCT05683314
- Testing
- Tranditional open reduction and internal fixation
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- China Medical University Hospital
Hip Fractures
Randomized Comparison of 2 Fixation Techniques for Unstable Intertrochanteric Hip Fractures
The purpose of this study is to compare the clinical and radiological outcome of patients that are treated with two different orthopedic implants.
- Trial name
- EMvsIM (NCT00597779)
- Testing
- Dynamic Hip Screw (DHS); Trochanteric Fixation Nail (TFN)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Rudy Reindl