Clinical trials: Upper Extremity Function, open to volunteers
Functional Constipation (FC)
The Beneficial Effect on the Bowel Function of a Food Supplement Based on Sea Buckthorn (Hippophae Rhamnoides L.) Extract in Subjects With Primary Functional Constipation
The study will aim to evaluate the efficacy and tolerability of a supplementation with Sea Buckthorn (Hippophae rhamnoides L.) at two different dosages for the management of the balance of intestinal function in subjects with…
- Trial name
- NCT07082673
- Testing
- Sea Buckthorn (Hippophae rhamnoides L.) botanical extract 500 mg., Sea buckthorn (Hippophae rhamnoides L.) 1500 mg.
- Where
- Italy
- Volunteers
- 135 people
- Sponsor
- ISTITUTO FARMOCHIMICO FITOTERAPICO: EPO SRL
Stroke
Acute Effects of Wearable Electrical Stimulation in Stroke
The goal of this clinical trial is to learn if the EXOPULSE Mollii Suit Wearable Electrical Stimulation works to reduce spasticity and improve functional capacity in individuals with stroke.
- Trial name
- NCT07459361
- Testing
- EXOPULSE Mollii Suit
- Volunteers
- 26 people
- Sponsor
- Hacettepe University
Scapular Dyskinesis
Scapular and Upper Limb Proprioceptive Neuromuscular Facilitation Techniques in Stroke With Scapular Dyskinesia.
This study aims to fill this gap by investigating the effects of scapular and upper limb proprioceptive neuromuscular facilitation techniques on shoulder pain, upper limb function \& gait in stroke with scapular dyskinesia.
- Trial name
- NCT07148466
- Testing
- Scapular PNF, Conventional treatment
- Where
- 2 sites in Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Stroke
Comparing Two Therapies to Improve Arm Function After Stroke
This clinical trial aims to compare the effects of coupling rehabilitation and constraint-induced movement therapy (CIMT) on improving arm function, hand skills, and daily activity performance in people who have upper limb…
- Trial name
- CR vs CIMT (NCT07093983)
- Testing
- Constraint-Induced Movement Therapy (CIMT), Coupling Rehabilitation
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- University of Lahore
Stroke
Comparing Perceptual Motor Training and Repetitive Facilitation Exercises on UE in Stroke
The aim of the study is to determine the comparative effects of perceptual motor training and repetitive facilitation exercises on upper limb quality of movement and motor function in Stroke patients.
- Trial name
- NCT06688812
- Testing
- Perceptual Motor Training, Repetitive Facilitation Exercises
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Female, Age ≥ 18 Years Old, No Previous Systemic Treatment for the Current Disease, Including Surgery, Antitumor Radiochemotherapy/Immunotherapy
Neoadjuvant Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer
Main Purpose of this study is to determine the efficacy and safety of Cadonilimab combined with chemotherapy (cisplatin) for locally advanced cervical cancer.
- Conditions
- Female, Age ≥ 18 Years Old, No Previous Systemic Treatment for the Current Disease, Including Surgery, Antitumor Radiochemotherapy/Immunotherapy, ECOG Score of 0-1, Histologically Confirmed Cervical Cancer, FIGO Stage IB3, IIA2, IIB, IIIC, and Assessed by the Researcher as Resectable Lesion
- Trial name
- NCT07104149
- Testing
- Cadonilimab combined with cisplatin
- Where
- China
- Volunteers
- 29 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Stroke
Potential for Recovery of Voluntary Finger Extension After Stroke
Stroke patients with absent voluntary finger extension (VFE) 6-months after stroke are not expected to recover hand function. However, experience from the Queen Square Upper Limb neurorehabilitation service contradicts this view.
- Trial name
- PROVES (NCT07592247)
- Testing
- Neuromuscular Electrical Stimulation and Home Exercise Programme
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College, London
Stroke With Hemiparesis
Home-based Graded Repetitive Arm Supplementary Program for Quality of Life and Functional Upper Limb Recovery
In post-stroke rehabilitation of the affected upper limb, increasing treatment intensity has been shown to lead to better outcomes compared to conventional approaches with fewer hours of therapy per day and week.
- Trial name
- REC-HOMEGRASP (NCT07146789)
- Testing
- occupational therapy combined with HomeGRASP program, occupational therapy
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Spinal Cord Injuries and Disorders (SCI/D)
Using Non-invasive Brain and Spinal Cord Stimulation to Improve Arm and Hand Function After Spinal Cord Injury
Cervical spinal cord injury (SCI) disrupts communication between the brain and spinal circuits, affecting voluntary movement control and contributing to arm and hand impairments, the top recovery priority for people with…
- Trial name
- NCT07423949
- Testing
- Cerebellar theta burst stimulation, Cervical transcutaneous spinal cord stimulation, Functional task practice
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of British Columbia
Stroke
The Effects of an Augmented Reality-Based Mirror Therapy System in Patients With Stroke
Objective The aim of this study is to investigate the effects of an augmented reality-based mirror therapy system (MirrARm), developed using sensor-based tracking and visual feedback principles, on upper extremity motor recovery…
- Trial name
- NCT07533734
- Testing
- Augmented Reality-Based Mirror Therapy, Conventional Mirror Therapy, Conventional Physiotherapy Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Marmara University
Peritoneal Dialysis Complication, End Stage Kidney Disease
meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsis
The primary aim of this study is to determine the safety and mechanisms of SGLT2 inhibition in individuals on peritoneal dialysis (PD) with residual kidney function (RKF).
- Conditions
- Peritoneal Dialysis Complication, End Stage Kidney Disease, Sodium-glucose Co-transporter-2 Inhibitors, Kidney Dysfunction
- Trial name
- CANARY (NCT05715814)
- Testing
- Empagliflozin 25 MG
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Spinal Cord Injury Cervical
Non-Invasive Neuromodulation for Upper Extremity Function in Spinal Cord Injury: A Crossover Trial
This study explores two promising therapies for restoring arm and hand function in people with chronic cervical spinal cord injury (SCI), a condition that affects independence and quality of life.
- Trial name
- NCT06903416
- Testing
- Transcutaneous Cervical Spinal Cord Stimulation, Paired Corticospinal Motoneuronal Stimulation, Functional Task Practice
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Alberta
Amputation, Congenital, Upper Limb; Amelia
CNS Changes Following Upper Limb Loss
The objective of this study is to better understand the structural and functional changes that the central nervous system (CNS) undergoes following congenital upper limb loss.
- Trial name
- NCT06043518
- Testing
- MRI
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Stroke
Proximal Priority Versus Distal Priority Robotic Priming Effects in Patients With Chronic Stroke
This is a single-blind randomized comparative efficacy study involving 54-72 participants with chronic stroke. Participants will be randomized into proximal priority robotic group or distal priority robotic group and receive 18…
- Trial name
- NCT04446273
- Testing
- Bi-Manu-Track
- Where
- 4 sites in Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Chronic Stroke
The Effect of Action Observation Therapy Including Unimanual and Bimanual Activities in Chronic Stroke
Functional impairments in the upper extremities following a stroke significantly restrict individuals' activities of daily living and overall quality of life; in this context, Action Observation Training (AOT) has emerged in…
- Trial name
- NCT07631169
- Testing
- Action Observation Therapy(unimanuel activities), Action Observation Therapy(bimanuel activities), conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Karabuk University
Multiple Sclerosis
Effects of Upper Extremity-Focused Neuromuscular Training in People With Multiple Sclerosis
The effectiveness of upper extremity focused neuromuscular exercise training in early stage people with MS will be investigated.
- Trial name
- NCT06712342
- Testing
- Neuromuscular Exercise Training, Conventional Exercise Training
- Volunteers
- 72 people
- Sponsor
- Istanbul Aydın University
Stroke, Hemiplegia and/or Hemiparesis Following Stroke
The Effect of Virtual Reality Therapy on Upper Extremity Functions in Subacute Stroke Patients Receiving Rehabilitation
Stroke ranks second among the leading causes of death worldwide and third among the causes of disability. In stroke patients, motor impairment typically affects facial movements and the upper and lower extremities unilaterally.
- Trial name
- NCT07299162
- Testing
- Virtual Reality, Conventional rehabilitation, Action observation therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Peripheral Arterial Disease
Local or Systemic Effects: Mechanisms Related to Arm Crank Exercise - Comparison Between Individuals With and Without PAD
INTRODUCTION: Exercise with an arm ergometer (EB) overcomes the main barrier to physical exercise in patients with Peripheral Artery Disease (PAD), leg pain during walking.
- Trial name
- NCT06828172
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Cognitive Impairment
The Effect of Upper Limb Low-intensity Motor Control Training Program on Cognitive Function in Healthy Older Adults
This healthy volunteer intervention study is designed to evaluate the effectiveness of upper limb motor control training (uMCT) on physical and cognitive functions in older adults.
- Trial name
- uMCON (NCT06962722)
- Testing
- Upper limb motor control training (uMCON)
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Peripheral Nerve Injury, Peripheral Nerve Discontinuity
Study Comparing Avance Nerve Graft and Autograft for Functional Recovery Following Mixed and Motor Peripheral Nerve Reconstruction
This is a multicenter, 1:1 randomized, prospective, comparative study in participants requiring reconstruction of a mixed or motor nerve in the upper extremity.
- Conditions
- Peripheral Nerve Injury, Peripheral Nerve Discontinuity, Mixed Peripheral Nerve Injury, Motor Peripheral Nerve Injury
- Trial name
- Nerve-RESTORE℠ (NCT07657182)
- Testing
- Avance Nerve Graft, Sural nerve autograft
- Where
- 3 sites in United States
- Volunteers
- 178 people
- Sponsor
- Axogen Corporation