Clinical trials: Upper Extremity Function
Developmental Coordination Disorder
Influence of Sensory Stimulation on Sensory Parameters and Motor Function in Children With Developmental Coordination Disorder
The goal of this clinical trial is to evaluate whether intensive sensory stimulation therapy can improve upper limb motor skills and sensory function in children aged 12-16 years with severe symptoms of Developmental Coordination…
- Trial name
- NCT06959329
- Testing
- Active and passive physical therapy without intensified sensory stimulation, Active and passive physical therapy with intensified sensory stimulation
- Where
- 2 sites in Latvia, Poland
- Volunteers
- 80 people
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Cerebral Palsy
Intensive Bimanual Intervention in Cerebral Palsy Children
Motor disorders related to cerebral palsy are often accompanied by sensory, cognitive, perceptive, communication and behavioural impairments.
- Trial name
- NCT05423171
- Testing
- Intensive bimanual therapy
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Follicular Lymphoma, Refractory Follicular Lymphoma
A Study to Assess Efficacy and Safety of Oral Tazemetostat in Adult Participants With Relapsed/Refractory Follicular Lymphoma That Does Not Have an "EZH2 Gain-of-function" Genetic Mutation
The purpose of this research study is to learn about the effectiveness and safety of the study drug, tazemetostat, in adults with relapsed/refractory follicular lymphoma whose tumours do not have an "EZH2 gain-of-function"…
- Trial name
- Mandolin (NCT06068881)
- Testing
- Tazverik (Tazemetostat)
- Sponsor
- Epizyme, Inc.
Stroke
Exercise-primed Upper Extremity Motor Practice in Chronic Stroke
The purpose of this project is to establish initial feasibility and tolerability of a combined aerobic exercise (AEx) and upper extremity motor practice intervention on upper extremity (UE) function in chronic stroke survivors.
- Trial name
- PUMP-Ex (NCT04259424)
- Testing
- Aerobic Exercise + Duck Duck Punch
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Medical University of South Carolina
Parkinson Disease
Effects of Telerehabilitation Versus Clinic-based Task-oriented Circuit Training in Parkinson's Patients
This randomized clinical trial aims to determine effects of Telerehabilitation versus clinic-based task-oriented circuit training on upper extremity functions and quality of life in Parkinson's patient.
- Trial name
- NCT06111924
- Testing
- Task oriented circuit training based telerehabilitation, Clinic based Task oriented circuit training
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Parkinson Disease (PD)
Effects of Dual-Task Training on Upper Extremity Function in Parkinson's Disease
The goal of this clinical trial is to investigate the effects of dual-task training on upper extremity function and muscle thickness in individuals with Parkinson's disease.
- Trial name
- NCT07536542
- Testing
- Dual-Task Training
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Ankara University
Healthy
Evaluation of the Impact of Laterality on Brain Activation During a Virtual Mirror Therapy Task in Healthy Subjects
The aim of this study is to investigate the differences in brain activation in healthy subjects during virtual mirror therapy tasks, depending on the laterality of the task.
- Trial name
- LARTHEMIRS (NCT05793762)
- Testing
- Left virtual mirror therapy task, Right virtual mirror therapy task
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Stroke
Does More Practice Improve Arm Movement After Stroke?
Arm weakness happens a lot after a stroke. People often get physical or occupational therapy after their stroke to learn how to use their arm again.
- Trial name
- NCT01146379
- Testing
- Intensive task-specific upper extremity rehabilitation
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Washington University School of Medicine
Spinal Cord Injuries
Upper Limb Ergometer on Pulmonary Function Among Patients With Spinal Cord Injury.
Randomized Control Trial, To determine the effects of arm ergometer exercise on pulmonary function of Spinal Cord Injury.
- Trial name
- NCT04358679
- Testing
- Conventional Treatment, Upper Limb ergometer training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Musculoskeletal Diseases or Conditions, Musculoskeletal Pain
Physical and Functional Effects of Online Exercise Program on Musicians Playing Stringed Instruments
Musculoskeletal problems related to instrument playing or performance are frequently seen in musicians. Different interventions such as strength training, endurance training and yoga have been used in the management of these…
- Trial name
- NCT06344988
- Testing
- The exercise program, Online education presentation, Smart band
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Bandırma Onyedi Eylül University
Multiple Sclerosis
Adaptive Plasticity Following Rehabilitation in Multiple Sclerosis
Motor learning can induce significant changes in the human brain through neural plasticity processes, which play a crucial role in the brain functional reorganization in response to external stimuli and/or to pathological…
- Trial name
- NCT03608527
- Testing
- Voluntary-based upper limb motor rehabilitation, Passive upper limb mobilization
- Volunteers
- 30 people
- Sponsor
- Fondazione Italiana Sclerosi Multipla
Stroke, Cerebrovascular Accident
Effect of Mirror Therapy and Task Oriented Training for Persons With Paretic Upper Extremity
The purpose of the study is to determine the effect of a combined mirror therapy and task oriented/repetitive task training on upper extremity function of persons with hemiplegia due to cerebrovascular accident or stroke.
- Trial name
- NCT02917343
- Testing
- mirror therapy and repetitive task training
- Volunteers
- 4 people
- Sponsor
- Quinnipiac University
Distal Radius Fracture, Chronic Regional Pain Syndrome
Effectiveness of Virtual Reality in Hand Therapy
The purpose of this study is to determine if the use of Virtual Reality as an intervention for patients following specific hand injuries will positively affect patients with decreased hand function and reduce pain and improve…
- Conditions
- Distal Radius Fracture, Chronic Regional Pain Syndrome, Flexor Tendon Rupture
- Trial name
- NCT05188040
- Testing
- Virtual Reality Exercises
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Timothy Uhl
Hemiplegia, Stroke
Impact of Physiotherapy on Spasticity, Upper Limb Function, Daily Activities, and Kinesiophobia in Hemiplegic Patients
This study investigated the effects of rehabilitation exercises on spasticity levels, upper extremity functions, activities of daily living, and kinesiophobia in patients with hemiplegia following a stroke.
- Trial name
- NCT06542848
- Testing
- Physiotherapy and Rehabilitation Practices
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- University of Beykent
Rehabilitation, Tenodesis, Stroke
Effectiveness of a Robot Assisted Tenodeis-grip Neurorehabilitation
In the proposed study, the investigators assumed that using robot assisted tenodesis-grip training providing high does assisted grip movement may do the effects on motor shaping and greater brain priming for hand paresis of the…
- Trial name
- NCT03713476
- Testing
- Motor task training
- Where
- Taiwan
- Volunteers
- 38 people
- Sponsor
- National Cheng-Kung University Hospital
Wrist Fractures
Early Functional Outcomes After Closed Reduction With Pinning Versus Open Reduction Internal Fixation of Wrist Fractures
The purpose of this study is to compare early return to function in patients treated with closed reduction percutaneous pinning and open reduction internal fixation in displaced fractures of the distal radius.
- Trial name
- NCT00828685
- Testing
- CRPP, ORIF
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
Spinal Cord Injuries
TCES for Upper Limb Function in Cervical SCI
Following a cervical spinal cord injury (cSCI; damage to the spinal cord at the neck) there is catastrophic loss of hand and grip function. This has a devastating effect on quality of life and functional independence.
- Trial name
- NCT05801536
- Testing
- SCONE
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Leeds
Upper Limb Dysfunction, Hand Function Impairment
3D-Printed Mobile Phone Holder for Individuals With Upper Limb Impairments
Individuals with upper limb functional impairments, such as those resulting from stroke, spinal cord injury, musculoskeletal disorders, or degenerative joint disease, often experience difficulties operating smartphones.
- Conditions
- Upper Limb Dysfunction, Hand Function Impairment, Musculoskeletal Disorders Affecting Hand Function, Difficulty Operating Smartphones Due to Upper Limb Impairment
- Trial name
- NCT07561944
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Multiple Sclerosis
Hand Grip Strength Correlates Strongly With Weekly Working Hours - the Importance of Upper Limb Function in Multiple Sclerosis
Multiple sclerosis (MS) as leading cause of non-traumatic neurological disability in young adults has additionally to the individual's burden of disease a significant influence on their ability to work.
- Trial name
- NCT07889271
- Testing
- hand grip strength
- Where
- Austria
- Volunteers
- 300 people
- Sponsor
- Salzburger Landeskliniken
Sickle Cell Disease (SCD)
Study Exploring the Effect of Crizanlizumab on Kidney Function in Patients With Chronic Kidney Disease Caused by Sickle Cell Disease
The goal of the study was to evaluate descriptively the effect of crizanlizumab + standard of care and standard of care alone on renal function in sickle cell disease patients ≥ 16 years with chronic kidney disease due to sickle…
- Trial name
- STEADFAST (NCT04053764)
- Testing
- Crizanlizuamb, Standard of Care
- Where
- 24 sites in United States, Brazil and 9 more
- Volunteers
- 58 people
- Sponsor
- Novartis Pharmaceuticals