Clinical trials: Upper Extremity Injury, open to volunteers
Bronchopulmonary Dysplasia
Safety and Efficacy of MSC-EVs in the Prevention of BPD in Extremely Preterm Infants
The phase 1/2 trial aims to evaluate the safety and efficacy of EXOB-001 consisting of extracellular vesicles derived from umbilical cord mesenchymal stromal cells in the prevention of bronchopulmonary dysplasia (BPD) in…
- Trial name
- EVENEW (NCT06279741)
- Testing
- Endotracheopulmonary Instillation, Suspension
- Where
- 8 sites in Belgium, Italy
- Volunteers
- 265 people
- Sponsor
- EXO Biologics S.A.
Bilateral Arthritis of Wrist, Tendinopathy
Vibratory Anesthesia on Pain Following Corticosteroid Injections
This research study aims to evaluate injectional pain at the site of needle insertion for corticosteroid injections (CSI) of the upper extremity depending on different modes of anesthetics.
- Conditions
- Bilateral Arthritis of Wrist, Tendinopathy, Arthropathy, Compression Neuropathy
- Trial name
- NCT07553273
- Testing
- Digivibe Device
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Wrist Fractures, Distal Radius Fractures
Unilateral Training of the Uninjured Limb on Clinical Outcomes in Patients with Surgically Treated Radius Fracture
The objective will be to determine the effectiveness of adding unilateral upper limb postoperative training to standard rehabilitation compared to standard rehabilitation on maximum grip strength and manual dexterity in patients…
- Trial name
- NCT06698367
- Testing
- Standard rehabilitation, Unilateral high-intensity strength exercise, Unilateral mobility exercises
- Where
- Chile
- Volunteers
- 52 people
- Sponsor
- Universidad Catolica de Temuco
Medial Epicondylitis, Telerehabilitation
Telerehabilitation vs Supervised Physiotherapy for Medial Epicondylitis
This randomized controlled trial aims to compare the effectiveness of telerehabilitation and supervised physiotherapy in patients with medial epicondylitis.
- Conditions
- Medial Epicondylitis, Telerehabilitation, Physiotherapy
- Trial name
- TELE-ME (NCT07582510)
- Testing
- Telerehabilitation Exercise Program, Supervised Physiotherapy Program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Lateral Epicondylitis, Medial Epicondylitis
Investigation of Obsessive-Compulsive Disorder in Patients With Elbow Epicondylitis
This study will compare obsessive-compulsive symptoms in adults with medial and/or lateral elbow epicondylitis (pain and tenderness on the inner and/or outer side of the elbow).
- Conditions
- Lateral Epicondylitis, Medial Epicondylitis, Obsessive-Compulsive Symptoms
- Trial name
- NCT07906379
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Fatih Turkmensoy
Lateral Epicondylitis (Tennis Elbow)
Comparison of Extracorporeal Shock Wave Therapy and Low-Level Laser Therapy in Patients With Lateral Epicondylitis
Background: Lateral epicondylitis is a common musculoskeletal condition characterized by pain and functional impairment of the elbow, often associated with degenerative changes in the common extensor tendon.
- Trial name
- NCT07564713
- Testing
- ESWT Group, LLLT Group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hitit University
Acquired Brain Injury
Development of a Soft Robotic Device for Rehabilitation and Assistance of the Upper Limb for People With Neurological Disorders
Development of a soft robotic device for rehabilitation and assistance of the upper limb for people with neurological disorders (FRONTIER)
- Trial name
- FRONTIER (NCT07750314)
- Testing
- FRONTIER Soft Exoskeleton
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Carpal Tunnel Syndrome (CTS), Wounds and Injuries, Hands
Evaluation of AI-Mouse Use in Patients With Hand and Wrist Conditions
People with hand and wrist conditions, such as carpal tunnel syndrome or hand injuries, often experience pain and discomfort when using a computer mouse.
- Conditions
- Carpal Tunnel Syndrome (CTS), Wounds and Injuries, Hands, Wounds and Injuries, Wrists, Hand Injuries
- Trial name
- NCT07707089
- Testing
- AI-Assisted Computer Input System, Conventional Computer Mouse
- Volunteers
- 15 people
- Sponsor
- Nazarbayev University
Sport Injuries
PNF Effects on Volleyball Performance
Volleyball is a team sport that demands high levels of skill and strategy; it has gained significant popularity in Türkiye, particularly among adolescents.
- Trial name
- NCT07913217
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uludag University
Lower Limb Amputation Above Knee (Injury)
Assessment of the Prosthetic System Impact on Mental Workload in Above-knee Lower Limb Amputees.
New generation of lower limb prosthesis provide improved functionalities. They are usually studied in the scope of biomechanics, sometimes PROMs like quality of life.
- Trial name
- INCREMENT (NCT06635655)
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Proteor Group
Distal Radius Fracture
"Supracondylar Radial Nerve Block Guided by Ultrasound Versus Hematoma Block for Analgesic Management in Closed Reduction of Distal Radius Fractures"
Non-surgical treatment with closed reduction and immobilization using a splint or cast is the preferred approach for stable distal radius fractures, particularly in elderly patients.
- Trial name
- NCT06857110
- Testing
- ultrasound-guided supracondylar block of the radial nerve, hematoma block, 5 mg of intramuscular diclofenac
- Where
- Colombia
- Volunteers
- 50 people
- Sponsor
- Hospital Universitario San Ignacio
Lateral Epicondylitis
Effect of Ultrasound-Guided Posterior Cutaneous Nerve of the Forearm Epicondylar Branch Block on Pain and Function in Lateral Epicondylitis (PCNF-BrEpi)
This study evaluates the effect of an ultrasound-guided posterior cutaneous nerve of the forearm epicondylar branch block on pain and functional status in patients with lateral epicondylitis.
- Trial name
- PCNF-BrEpi (NCT07894718)
- Testing
- Ultrasound-guided triamcinolone injection, Ultrasound-guided PCNF-BrEpi block, Conventional therapy (home exercise program and epicondylitis band)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Spinal Cord Injury Cervical
Combining Spinal Cord Transcutaneous Stimulation and Activity-based Training in Inpatient Rehabilitation to Facilitate Upper Limb Function of Individuals with Acute to Subacute Cervical Spinal Cord Injury
The purpose of this clinical trial is to understand the safety and practicality of using spinal cord transcutaneous (through the skin) stimulation in an inpatient setting as well as how the combination of activity-based training…
- Trial name
- NCT06773286
- Testing
- Active Stimulation, Training only
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kessler Foundation
Muscle Spasticity, Spinal Cord Injury
Comparing Upper Limb Surgery and Botulinum Toxin for Spasticity: A Paired Design Study
Spasticity is a common complication following central nervous system injuries. Left untreated, spasticity can lead to various complications, hindering activities of daily living and diminishing independence.
- Conditions
- Muscle Spasticity, Spinal Cord Injury, Stroke, Traumatic Brain Injuries
- Trial name
- NCT06733025
- Testing
- Tendon lengthening surgery, BoNT Injections
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Vastra Gotaland Region
Distal Radius Fracture
Home-Based Photobiomodulation Effects in the Postoperative Period of Distal Radius Fractures
This double-blind, randomized controlled clinical trial aims to evaluate the adjuvant effect of home-based photobiomodulation (PBM) therapy on the rehabilitation of surgically treated DRFs combined with an unsupervised home…
- Trial name
- NCT07426926
- Testing
- Open reduction and internal fixation (ORIF) with locked volar plate, Home exercises, Active photobiomodulation
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Elbow Injury
MDR ExploR Radial Head System PMCF
The objective of this retrospective and prospective consecutive series PMCF study is to collect long-term data confirming safety, performance and clinical benefits of the ExploR Radial Head System (implants and instrumentation)…
- Trial name
- NCT05583448
- Testing
- ExploR Radial Head
- Where
- 2 sites in United States, Norway
- Volunteers
- 93 people
- Sponsor
- Zimmer Biomet
Distal Radius Fracture
Kinesiophobia and Functional Outcomes in Distal Radius Fractures
Distal radius fractures are among the most common fractures in adults and are frequently treated with closed reduction and cast immobilization.
- Trial name
- NCT07668531
- Testing
- Conservative Treatment of Distal Radius Fracture
- Volunteers
- 100 people
- Sponsor
- Ebru Aloğlu Çiftçi
IgA Nephropathy (IgAN), Immunoglobulin A Nephropathy (IgAN)
Mechanistic Evaluation of Atrasentan in Patients With IgA Nephropathy (IgAN)
This multicenter, single-arm, open-label Phase 4 pilot study evaluates the effects of atrasentan added to optimized supportive care on kidney structure and function in adults with biopsy-confirmed IgA nephropathy.
- Trial name
- A-MECH (NCT07820995)
- Testing
- atrasentan
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Illinois Chicago
Incomplete Spinal Cord Injury, Spinal Cord Injury
Effectiveness of Virtual Bodily Illusion Intervention in Upper Limb Motor Function in People With Incomplete Spinal Cord Injury.
Previous studies have shown that the neuroplasticity of the residual corticospinal fibers, the motor cortex and the spinal neurons plays an important role in the spontaneous functional recovery of people with neurological or…
- Trial name
- NCT05142943
- Testing
- Visual illusion, Physical exercise
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Valencia
Spinal Cord Injury Cervical, Tetraplegia
Epidural Stimulation for Upper Extremity Function
Restoring upper extremity function in patients with cervical spinal cord injury is extremely important for patients' independence and quality of life.
- Trial name
- NCT06437548
- Testing
- Percutaneous spinal cord stimulation
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital