Clinical trials: Upper Extremity Paralysis
Hemiplegia, Spasticity
Upper Limb Nerve Cryoneurolysis is Non Inferior to the Usual Care and Has Therapeutic Add Value in Dealing With Shoulder Pain and Functional Problems Caused by Spasticity and Motor Impairment
This trial is part of the spastiCRYO clinical research project. The primary objective of this clinical trial is to test the hypothesis: "Upper limb nerve cryoneurolysis is non inferior to the usual care and has therapeutic add…
- Conditions
- Hemiplegia, Spasticity, Shoulder Spasticity, Shoulder Stiffness
- Trial name
- spastiCRYO-UL (NCT06782464)
- Testing
- Treatment
- Where
- Luxembourg
- Volunteers
- 50 people
- Sponsor
- Centre National de Rééducation Fonctionnelle et de Réadaptation
Quadriplegia, Spinal Cord Diseases
Nerve Transfers to Restore Hand Function in Spinal Cord Injury
This study seeks to evaluate the efficacy of nerve transfers in restoring hand function in patients with cervical spinal injuries.
- Conditions
- Quadriplegia, Spinal Cord Diseases, Spinal Cord Injuries
- Trial name
- NCT02861612
- Testing
- Nerve Transfer Surgery
- Where
- 2 sites in United States, Canada
- Sponsor
- Ottawa Hospital Research Institute
Cerebral Palsy, Prosthesis User
Use of Low Cost Prostheses to Improve Upper Extremity Function in Children With Cerebral Palsy
The purpose of the study is to assess the effectiveness of an upper extremity prosthesis in improving the upper extremity function of children with cerebral palsy who have limited use of their hands.
- Trial name
- NCT03122171
- Testing
- Occupational Therapy Treatment
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Cerebral Palsy
Effectiveness of Unilateral Versus Bilateral Intensive Training in Children With Cerebral Palsy
This 3-year research project aims to investigate and compare the immediate and long-term treatment effectiveness as well as motor improving curve and potential predictors of the unimanual intensive training and bimanual intensive…
- Trial name
- NCT02808156
- Testing
- unilateral upper limbs intensive training, bilateral upper limbs intensive training
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Stroke, Hemiplegia
The Effect of Blood Flow Restriction Training Combined With Transcranial Magnetic Stimulation on Limb Function in Hemiplegic Patients After Stroke
This randomized controlled trial aims to evaluate whether combining blood flow restriction training (BFRT) with repetitive transcranial magnetic stimulation (rTMS) improves limb function in stroke patients with hemiplegia.
- Trial name
- BFR-TMS-Stroke (NCT07454954)
- Testing
- Conventional Rehabilitation, Repetitive Transcranial Magnetic Stimulation (rTMS), Blood Flow Restriction Training (BFRT)
- Volunteers
- 69 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis
Spinal Cord Associative Plasticity Study
Spinal cord associative plasticity (SCAP) is a combined cortical and spinal electrical stimulation technique developed to induce recovery of arm and hand function in spinal cord injury.
- Conditions
- Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
- Trial name
- SCAP (NCT05163639)
- Testing
- Non-invasive pairing of cortical and spinal stimulation, Intraoperative pairing of cortical and spinal stimulation, Non-invasive repeated pairing of cortical and spinal stimulation (SCAP)
- Where
- 3 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cerebral Palsy, Spastic
Effect of Pully System on Hemiplegic Children
Introduction Cerebral palsy (CP) is a group of sensory, motor, and postural disorders caused by non-progressive brain injury in early development.
- Trial name
- NCT06434246
- Testing
- pulley system exercise regimen, physical therapy program for CP
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Kafrelsheikh University
Cerebrovascular Accident, Hemiplegia
The Effect of Different Schedules of Functional Task Practice for Improving Hand and Arm Function After Stroke
The first purpose of this study is to determine how often people should practice motor skills to best improve the ability to use the affected arm and hand after stroke.
- Trial name
- NCT00361660
- Testing
- functional task practice - distributed, functional task practice - condensed
- Sponsor
- US Department of Veterans Affairs
Diplegic Cerebral Palsy
Action Observation in Children With Diplegic Cerebral Palsy
A new rehabilitative approach, called AOT, based on the discovery of mirror neuron system (MNS), has been used with promising results on the Upper Limb (UL) function in some studies in children with Cerebral Palsy (CP).
- Trial name
- NCT05223257
- Testing
- AOT
- Where
- 3 sites in Italy
- Volunteers
- 54 people
- Sponsor
- IRCCS Fondazione Stella Maris
Hemiparesis, Unilateral Cerebral Palsy
Effects and Mechanisms of Sensory Afferent Electrostimulation on Upper Limb Function in Patients With Hemiparesis
The goal for this project is to investigate the effects of a 5-week SAES therapy in addition to conventional therapy on both behavioural (sensory and motor) and neurological measures and the underlying mechanisms of treatment…
- Trial name
- SAES (NCT06536634)
- Testing
- SAES, TAU
- Where
- Switzerland
- Volunteers
- 34 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cerebral Palsy
Mirror Therapy With Sensory Motor Training in Children With CP
The study compares two interventions in CP children: mirror therapy with sensory motor training versus mirror therapy with motor training.
- Trial name
- NCT06292416
- Testing
- Experimental: Mirror therapy with sensory motor training., Experimental: Mirror Therapy with motor training, Experimental: Motor Training
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Stroke, Hemiplegia
Effects of Mirror Therapy and Bilateral Arm Training on Hemiparetic Upper Extremity in Patients With Chronic Stroke
The aim of this study included (1) to compare the effectiveness of mirror therapy (MT) and bimanual arm training (BAT) in improving motor and functional performance of hemiplegic upper extremity for adults with chronic stroke…
- Trial name
- NCT04242316
- Testing
- Mirror Therapy, Bilateral arm training
- Volunteers
- 101 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke, Acute, Hemiplegia
Effects of High Frequency rTMS Combined Motor Learning on Upper Limb Motor Function in Subacute Stroke
This study is to present the effect of a program combining high frequency repetitive transcranial magnetic stimulation with motor learning on upper limb motor function and grip strength and activities of daily motion in patients…
- Trial name
- NCT05176613
- Testing
- HF-rTMS, ML
- Volunteers
- 30 people
- Sponsor
- Chungnam National University Sejong Hospital
Cervical Spinal Cord Injury, Tetraplegia
Testing the Decision Aid: Supporting Patient Decisions About Upper Extremity Surgery in Cervical SCI
Purpose: The objective of this study is to assess a newly created decision support intervention (DSI) or decision aid (DA) for people with spinal cord injury (SCI) to learn about and consider upper extremity reconstructive…
- Trial name
- NCT04995796
- Testing
- Surveys for Research Purposes
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Erbs Palsy
Effects of Scapular Mobilization on Upper Limb Function
Erb's Palsy is a physical impairment resulting from an injury to the upper trunk of the brachial plexus and is associated with paralysis of the upper limb.
- Trial name
- NCT06198218
- Testing
- Scapular mobilization, Conventional physical therapy program
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hemiplegia, Aphasia
The Effect of Upper Extremity Motor Function, Trunk Control and Motor Imagery Ability on Turkish Language Skills in Individuals With Stroke
A large number of people have a stroke each year and it is a major cause of disability worldwide. Upper limb motor impairments, aphasia, body control problems and decreased motor imagery ability are common after stroke.
- Conditions
- Hemiplegia, Aphasia, Stroke, Trunk
- Trial name
- NCT06946082
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Izmir Bakircay University
Neurological Conditions, Brain Diseases
NEO-REEDUC - Mixed Reality for Motor Rehabilitation: a Prospective, Multicenter, Controlled, Randomized, Open Study.
This study aims to assess the effectiveness of a motor rehabilitation protocol that includes mixed reality activities, compared to conventional rehabilitation, on postural stability in children and adult patients with…
- Conditions
- Neurological Conditions, Brain Diseases, Cerebral Palsy, Parkinson Disease (PD)
- Trial name
- NCT07063810
- Testing
- Mixed Reality Rehabilitation
- Where
- 5 sites in France
- Volunteers
- 76 people
- Sponsor
- Slb Pharma
Spinal Cord Injury Cervical, Spinal Cord Injuries (Complete and Incomplete)
Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia
The goal of this clinical trial is to learn more about how stimulating the nerves involved in sensation (either in the limbs or in the brain) can be used to restore sensation in participants who have a spinal cord injury.
- Trial name
- NCT07225582
- Testing
- Brain Computer Interface (BCI) - Functional Electrical Stimulation (FES) system
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Case Western Reserve University
C5 Palsy
Conventional-therapy & FES-therapy In-Veritas Effects Study
This randomized clinical trial will primarily compare the effectiveness of conventional physiotherapy alone with combined conventional physiotherapy and FES-t along with task-specific training in terms of the improvement of the…
- Trial name
- C-FIVE (NCT05247450)
- Testing
- Functional electrical stimulation therapy (FES-t), Conventional physiotherapy
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University Health Network, Toronto