Clinical trials: Upper Extremity Surgery
Obesity/therapy
Rhomboid Intercostal Block with Subserratus Plane Block in Bariatric Surgery
Standard analgesic techniques such as patient-controlled analgesia (PCA) and continuous epidural analgesia (CEA) are effective but associated with considerable side effects, including nausea, hypotension, and respiratory…
- Trial name
- NCT06729515
- Testing
- PCA, CEA, RISS
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Xiaguang Duan
Esophagus Cancer
Neoadjuvant Comprehensive Treatment for Unresectable Esophageal Cancer
Patients diagnosed with locally advanced esophageal squamous cell carcinoma (ESCC) that is deemed unresectable face a bleak prognosis.
- Trial name
- NEXUS-2 (NCT06430658)
- Testing
- Tislelizumab (BGB-A317) with chemoradiotherapy
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Proximal Humerus Fracture
Hanover Humerus Registry
This register study collects data of patients with proximal humerus and humerus shaft fractures to monitor the healing process by assessing shoulder function and quality of life according to the treatment method (operative or…
- Trial name
- HHR (NCT03060876)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Hannover Medical School
Lymphedema, Lymphedema Arm
The Robot-LVA Study: Robot-assisted Microsurgical Lymphaticovenous Anastomosis in Breast Cancer-related Lymphedema
This study assesses the performance of robot-assisted microsurgery. Lymphaticovenous anastomosis (LVA) is the most difficult procedure in microsurgery at this moment.
- Conditions
- Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Lymphedema of Upper Limb
- Trial name
- NCT06532955
- Testing
- Lymphaticovenous anastomosis using Microsure Motion Stabilizer, Lymphaticovenous anastomosis (manual)
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Cataract
Evaluation of 3 Intraocular Lenses Following Lens Extraction
The objective of this study is to evaluate the efficacy and subject satisfaction with three different FDA approved lenses for adults over 40 years of age who desire a reduction in spectacle dependence.
- Trial name
- NCT01122576
- Testing
- Crystalens AO, ReSTOR, Tecnis Multifocal IOL
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Bausch & Lomb Incorporated
Prostate Cancer
Postoperative Patient Comfort and Quality of Micturition in Suprapubic Tube vs. Transurethral Catheterization After RARP
The purpose of the study is to determine, whether the postoperative quality of micturition and continence can be improved depending on the urinary drainage catheter and retention after robot assisted radical prostatectomy.
- Trial name
- MPH (NCT02812173)
- Testing
- suprapubic tube ex 2 day, suprapubic tube ex 5 day, transurethral catheter ex 5 day
- Where
- Germany
- Volunteers
- 234 people
- Sponsor
- St. Antonius Hospital Gronau
Malignant Melanoma, Sinonasal Melanoma
Toripalimab Combined With Radiotherapy and Chemotherapy in the Treatment of SNMM After Endoscopic Surgery
Phase II, single-arm, prospective clinical study of Toripalimab(a PD-1 antibody) combined with radiotherapy and chemotherapy in the treatment of sinonasal malignant mucosal melanoma after endoscopic surgery.
- Trial name
- SNMM (NCT04879654)
- Testing
- endoscopic surgery
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Nerve Block, Upper Extremity Surgery
Ropiclobet for Regional Anesthesia and Post-Operative Pain Control in Upper Extremity Surgery
This is a national, single-center, single-arm, open-label Phase II clinical trial designed to evaluate the efficacy and safety of Ropiclobet, a fixed-dose injectable solution containing Ropivacaine HCl, Betamethasone Sodium…
- Trial name
- NCT07131657
- Testing
- Ropivacaine + Clonidine + Betamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- PHARMAFINA
Acute Major Bleeding, Reversal of Coagulopathy
Study of a Prothrombin Complex Concentrate for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Japanese Subjects
The purpose of this study is to evaluate efficacy and safety of a Prothrombin Complex Concentrate (PCC), BE1116. BE1116 will be used for the rapid reversal of coagulopathy induced by vitamin K antagonists in Japanese subjects who…
- Trial name
- NCT02281201
- Testing
- BE1116 (Prothrombin Complex Concentrate)
- Where
- 11 sites in Japan
- Volunteers
- 11 people
- Sponsor
- CSL Behring
Pain
the Best Approach for Blocking Intercostobrachial and Medial Brachial Cutaneous Nerves in the Upper Arm Surgery
Brachial plexus block (BPB) alone, whether performed at the axilla or more proximally, does not provide sufficient anesthesia for the skin of the medial upper arm and elbow, because thoracic roots contribute to the innervation of…
- Trial name
- NCT05864872
- Testing
- axillary brachial plexus block
- Where
- Tunisia
- Volunteers
- 140 people
- Sponsor
- Olfa kaabachi, MD
Upper Extremity Surgery, Regional Anesthesia
Brachial Plexus Block vs General Anesthesia in Upper Extremity Surgery
This study compares two different anesthesia methods for upper arm and hand surgery: regional anesthesia (brachial plexus block) versus general anesthesia.
- Conditions
- Upper Extremity Surgery, Regional Anesthesia, General Anesthetic
- Trial name
- NCT07352839
- Testing
- Brachial Plexus Block, General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Adana City Training and Research Hospital
Pedicle Screws, Surgery, Computer-Assisted/Adverse Effects
Pedicle Screws Placement Accuracy in Thoracolumbar Spine Using O-arm Navigation VS Standard Cervical Distractor Screws
Pedicle screw instrumentation is used nowadays mostly in spine fusion which is a surgical option for treating variety of conditions such as vertebral fractures, degenerative spine diseases, spine tumors and spine deformities.
- Conditions
- Pedicle Screws, Surgery, Computer-Assisted/Adverse Effects, Bone Screws, Imaging, Three-Dimensional/Methods
- Trial name
- NCT04196153
- Testing
- Pedicle screws instrumentation
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Abdullah International Medical Research Center
Colon Cancer, dMMR Colorectal Cancer
Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers
This is a Phase II, single arm study looking at the rate of major clinical response and non-operative management in Stage II and III colon cancer after 18 weeks (up to 6 cycles) of neoadjuvant dostarlimab.
- Trial name
- NAIO (NCT05239546)
- Testing
- Dostarlimab
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of Iowa
Humerus Fracture
Low Dose Interscalene and Infraclavicular Block for Humerus Surgery
Combining interscalene block with infraclavicular block for humerus surgery provides a unique surgical anaesthesia and postoperative analgesia.
- Trial name
- NCT02756156
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Prostate Cancer, Cholelithiases
A Prospective, Single-center, Single-arm, Pivotal Trial of the Medtronic Hugo™ Robotic Assisted Surgery (RAS) System
The goal of this clinical trial is to test the safety and effectiveness of the Medtronic Hugo™ RAS System in patients undergoing a prostatectomy or a cholecystectomy.
- Conditions
- Prostate Cancer, Cholelithiases, Cholecystitis, Gallbladder Polyp
- Trial name
- NCT05715827
- Testing
- RAS prostatectomy and RAS cholecystectomy
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Medtronic - MITG
Surgery
Risk Factors and Prevention of Severe Pain Upon Cessation of a Peripheral Nerve Block
Risk factors and Prevention of severe Pain upon cessation of a peripheral nerve block. A prospective randomized study in ambulatory patients undergoing upper limb bone surgery under single shot axillary plexus block.
- Trial name
- PRPK (NCT04890418)
- Testing
- Ketalar, 5 mg/mL Injectable Solution
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Neurofibromatosis 1
The Clinical Study of the Treatment of Patients With Type I Neurofibromatosis With Smetinib Hydrosulfate Capsule
This study focused on patients with type I neurofibromatosis undergoing surgical treatment, who currently lack effective drug therapy and have a high recurrence rate after surgical resection.
- Trial name
- NCT06621082
- Testing
- Selumetinib
- Volunteers
- 19 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Hemorrhage, Blood Loss
Clinical Investigation Evaluating a New Autotransfusion Device in Cardiac Surgery
Blood transfusion is at the heart of the therapeutic arsenal when there is a hemorrhage and/or blood loss during a surgery. There are two types of transfusion: the homologous one (blood from a compatible donor) and the autologous…
- Conditions
- Hemorrhage, Blood Loss, Surgical Blood Loss
- Trial name
- i-TRANSEP (NCT04588350)
- Testing
- i-SEP autotransfusion system
- Where
- 5 sites in France
- Volunteers
- 50 people
- Sponsor
- i-SEP
Distal Radius Fracture, Distal Radius Fracture Fixation
Enhancing Patient Engagement and Communication Through the Use of 3-Dimensional Printed Surgical Wrist Anatomy Models
Single blinded Randomised Controlled Trial - standardised 3-Dimensional printed 1:1 distal radius fracture configuration - 60 patients.
- Trial name
- NCT07872488
- Testing
- 3D printed Distal Radius Fracture Model
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Postoperative Wound Infection Superficial Incisional, Postoperative Wound Infection Deep Incisional Surgical Site
Safety and Efficacy of D-PLEX in the Prevention of Sternal Infection Post Cardiac Surgery.
This study is aimed to assess the anti-infective efficacy of D-PLEX over a period of 3 months post operation as well as the safety over a period of 6 months, by preventing sternal infection post cardiac surgery in patients above…
- Trial name
- NCT02731573
- Testing
- D-PLEX, Open heart surgery
- Where
- 5 sites in Israel
- Volunteers
- 81 people
- Sponsor
- PolyPid Ltd.