Clinical trials: Upper Extremity Wound
Humeral Fractures
Humeral Compression/Distraction Device
The proposed study of humeral shaft fractures in adults will examine outcomes in patients treated with the Humeral Trauma Nail System to treat displaced humeral shaft fractures (displaced OTA code 12A, B, or C), nonunions, or…
- Trial name
- NCT02861495
- Testing
- Humeral Compression/Distraction (CD) Nail
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Florida Orthopaedic Institute
Distal Radius Fractures, Fracture of Lower End of Radius
Compression Gloves for Distal Radius Fracture
Distal Radius Fractures are among the most common orthopedic injuries. Rehabilitation may be characterized by pain, stiffness, swelling, and decreased range of motion (hand and fingers), and grip strength.
- Conditions
- Distal Radius Fractures, Fracture of Lower End of Radius, Colles' Fracture, Smith's Fracture
- Trial name
- NCT01518179
- Testing
- Made-to-Measure Compression Gloves, Routine follow up and treatment
- Where
- 2 sites in Israel
- Volunteers
- 35 people
- Sponsor
- Clalit Health Services
Analgesia, Acute Pain
Pharmacokinetic Analysis of Bupivacaine in the Presence and Absence of Perineural Dexamethasone in Axillary Blockade
The investigators will conduct a prospective, randomized, double-blinded study using an axillary brachial plexus block in patients undergoing elective surgery of the distal forearm and hand to characterize and describe the…
- Conditions
- Analgesia, Acute Pain, Upper Extremity Injury
- Trial name
- NCT05359731
- Testing
- Bupivacaine Hydrochloride, Bupivacaine Hydrochloride with Dexamethasone
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
Rotator Cuff Tear
Outcomes in Rotator Cuff Repair Using Graft Reinforcement
The purpose of this study is to evaluate patient shoulder functional outcomes following rotator cuff repairs reinforced with a surgical mesh.
- Trial name
- NCT01025037
- Testing
- Conexa Reconstructive Tissue Matrix
- Where
- 6 sites in United States
- Volunteers
- 61 people
- Sponsor
- Stryker Trauma and Extremities
Distal Radius Fracture
Short Forearm Casting Versus Below-elbow Splinting for Acute Immobilization of Distal Radius Fractures
There is no consensus regarding the need to immobilize the elbow in immediate immobilization of closed distal radius fractures post-reduction.
- Trial name
- NCT02679066
- Testing
- Sugar-tong splint, Short forearm cast
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Osteoporosis, Fractures
Strategies Targeting Osteoporosis to Prevent Recurrent Fractures
An evidence-based quality improvement intervention will overcome multiple barriers to best practice and improve rates of diagnosis and effective treatment for osteoporosis in high-risk patients.
- Trial name
- NCT00152321
- Testing
- Patients (education, counseling) and Physicians (reminders,1-page guidelines)., Multifaceted intervention, Usual Care
- Where
- Canada
- Volunteers
- 242 people
- Sponsor
- University of Alberta
Secondary Prevention
Early Mobilisation of the Distal Radius Fracture
The goal of this clinical trial is to demonstrate the effectiveness of early therapy in 14 patients with a distal radius fracture DRF resulting from injury, as the study group.
- Trial name
- NCT06258928
- Testing
- Functional examination
- Where
- Poland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Postoperative Pain, Carpal Tunnel Release
Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries
The purpose of this study is to determine the efficacy of intra-operative administration of IV tylenol and/or IV toradol in minimizing post-operative pain for carpal tunnel patients and distal radius fracture patients.
- Conditions
- Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
- Trial name
- NCT02313675
- Testing
- Acetaminophen, Ketorolac Tromethamine, Saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- John Fowler
Lateral Epicondylitis, Central Sensitization
Central Sensitization and Ultrasound in Lateral Epicondylitis
Lateral epicondylitis (LE) is a common musculoskeletal disorder characterized by pain and tenderness over the lateral elbow and may become chronic despite conservative treatment.
- Trial name
- NCT07827898
- Testing
- Pressure pain threshold, Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Radiation Injuries
Effect and Safety of Apatinib on Radiation-Induced Brain Injury
Purpose: This early phase 2 clinical trial aims to evaluate the therapeutic effects and safety of apatinib in radiation-induced brain injury.
- Trial name
- NCT04152681
- Testing
- Apatinib
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Knee Injuries and Disorders
Different Arm Positions During Single Leg Squat
The aim of this study is to compare the effects of different arm positions on muscle activity during single leg squat.
- Trial name
- NCT05420675
- Testing
- Single Leg Squat
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Distal Radius Fractures, Fractures, Bone
Three Weeks of Cast Immobilisation Versus One Week of Brace Immobilisation in Distal Radius Fractures
Three weeks of cast immobilisation versus one week of brace immobilisation in non- or minimally displaced distal radius fractures in adult patients <50 years of age treated non-operatively.
- Trial name
- DRPIPIII (NCT06235957)
- Testing
- Cast 3 weeks, Brace 1 week
- Where
- 3 sites in Netherlands
- Volunteers
- 74 people
- Sponsor
- Spaarne Gasthuis
Wrist Injury, Hand and Upper Limb Trauma
Virtual Reality-based Rehabilitation for Traumatic Hand and Wrist Injuries
This randomized controlled trial aims to evaluate the effectiveness of immersive virtual reality (VR)-based Action Observation Therapy (AOT) as an adjunct to conventional rehabilitation in patients with traumatic wrist and hand…
- Conditions
- Wrist Injury, Hand and Upper Limb Trauma, Hand and Forearm Trauma, Muskuloskeletal Diseases
- Trial name
- AOT-VR-HAND (NCT07633769)
- Testing
- Immersive Virtual Reality Action Observation Therapy, Conventional Rehabilitation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Malaga
Radius; Fracture, Lower or Distal End
Cast vs. Splints for Minimally Displaced Distal Radius Fractures in the Elderly
The purpose of this prospective randomized study is to add to the body of knowledge on the treatment of minimally displaced distal radius fractures in patients over 60 years of age.
- Trial name
- NCT02066857
- Testing
- Cast made of generic plaster or fiberglass cast material, Generic "off the shelf" removable splint
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Emory University
Bone Fracture, Radius Fracture
Study on Wood-plastic Composite for Circumferential Casting
The purpose of study is to verify that WOODCAST Circular system performs safely and effectively in its intended use.
- Conditions
- Bone Fracture, Radius Fracture, Ankle Fracture
- Trial name
- WOODCAST (NCT01493167)
- Testing
- limb casting/splinting
- Where
- Finland
- Volunteers
- 97 people
- Sponsor
- Onbone Oy
Upper Limb Amputation Below Elbow (Injury), Wrist Disarticulation
Evaluation of the Phantom X Implantable EMG Sensor System for Myoelectric Prosthesis Control
The CYBORG Study is a first-in-human clinical investigation evaluating the safety and performance of the Phantom X System, an implantable electromyography (EMG) sensor array designed to provide control of upper-limb prostheses.
- Conditions
- Upper Limb Amputation Below Elbow (Injury), Wrist Disarticulation, Transradial Amputation
- Trial name
- CYBORG (NCT07325708)
- Testing
- Phantom X multielectrode EMG sensor array implant for upper limb prosthesis control
- Where
- 2 sites in Australia
- Volunteers
- 10 people
- Sponsor
- Phantom Neuro Inc.
Upper Limb Deficits
Assessment of Feasibility, Functionality and Usability of an Hybrid Assistive Exoskeleton for Upper Limb
People affected by stroke or brachial plexus injuries experience huge impairment in using upper limbs for everyday life activities.
- Trial name
- NCT07000279
- Testing
- Assistive exoskeleton for activities of daily living (ADLs), Assistive exoskeleton for box and block, Assistive exoskeleton for maximum reaching height
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Pyoderma Gangrenosum, Skin Diseases
Guselkumab in the Treatment of Adults With Pyoderma Gangrenosum (PG)
A single-arm open-label study assessing short-term (week 6, 16) and long-term (week 32) efficacy of guselkumab in adult participants with pyoderma gangrenosum (PG)
- Conditions
- Pyoderma Gangrenosum, Skin Diseases, Wound Heal, Pyoderma
- Trial name
- GEORGE (NCT06563323)
- Testing
- Guselkumab
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Oregon Health and Science University
Lateral Epicondylitis
Treatment of Intractable Common Extensor Tendon Injury Using Mesenchymal Stem Cells (Allo-ASC)
The aim of this study is to evaluate the efficacy and safety of intra-tendon injection of allogeneic adipose-derived mesenchymal stem cells (Allo-ASC) in intractable common extensor tendinosis patients in comparison with a…
- Trial name
- NCT03449082
- Testing
- High concentration of Allo-ASC, Low concentration of Allo-ASC, Fibrin glue
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Humerus Fractures, Closed Fracture of the Proximal Humerus
PHILOS Augmented - a Multicenter Randomized Controlled Trial
The primary objective is to compare the mechanical failure risks in the first year after treatment.
- Trial name
- NCT01847508
- Testing
- PHILOS+, PHILOS
- Where
- 9 sites in Austria, Belgium and 2 more
- Volunteers
- 69 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
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