Clinical trials: Upper Extremity Wound
Distal Radius Fracture
Minimally Invasive Fixation for Distal Radius Fractures
Minimally invasive surgery avoids the tissue damage and impairment of physiological function caused by open surgery because of its precise location techniques and can effectively promote the early recovery of wrist function.
- Trial name
- DRF (NCT05175118)
- Testing
- Minimal invasive surgical fixation of distal radius Fractures
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
SCI - Spinal Cord Injury, SCI
NeuroRise: Intrathecal CE-1 Treatment for Traumatic SCI
The purpose of this study is to assess the safety and tolerability of intrathecal administration of CE-1 at a weight-based dose (cells/kg BW), capped at a maximum total dose of 1×10⁸ cells in 10 mL, with administered volume…
- Conditions
- SCI - Spinal Cord Injury, SCI, Spinal Cord Injury
- Trial name
- NeuroRise (NCT07739043)
- Testing
- Human allogeneic, culture expanded, UC-MSC
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Cell Therapy LLC
Distal Forearm Fracture, Distal Radius Fracture
Is Casting of Displaced Pediatric Distal Forearm Fractures Non-inferior to Reduction in General Anesthesia?
Treatment of displaced distal forearm fractures (DFF) in children have traditionally been closed reduction and pin fixation, although they might heal and remodel without manipulation, with no functional impairment.
- Trial name
- CASTING (NCT05736068)
- Testing
- Non-surgical treatment, Surgical treatment
- Where
- 4 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Zealand University Hospital
Elbow Fracture
Steroid Administration for Articular Fractures of the Elbow (SAFE Trial)
The primary purpose of this study is to determine if perioperative glucocorticoid administration (IV intra-operative followed by a post-operative oral taper course) improves post-operative range of motion in a patient population…
- Trial name
- SAFE (NCT04738318)
- Testing
- Glucocorticoids, Saline
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Vanderbilt University Medical Center
Diabetic Foot Ulcer, Non-healing Diabetic Foot Ulcer
EPC Silver Wound Gel (EPC-123) Feasibility Study in the Management of Mildly Infected Diabetic Foot Ulcers
The objective of this single-arm feasibility study is to investigate the safety and impact of the topical EPC Silver Wound Gel (EPC-123) in the management of diabetic foot ulcer wounds not progressing under the current standard…
- Conditions
- Diabetic Foot Ulcer, Non-healing Diabetic Foot Ulcer, Diabetic Foot Infection
- Trial name
- NCT05243810
- Testing
- EPC Silver Wound Gel
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Exciton Technologies Inc.
Tennis Elbow
Eccentric Exercise or Radiofrequent Microtenotomy as Treatment of Lateral Epicondylalgia
The aim is to study the effects related to function and pain during eccentric exercise and surgery with radiofrequency microtenotomy as post-surgical rehabilitation, compared with only eccentric exercise, in patients with lateral…
- Trial name
- NCT02304952
- Testing
- Radiofrequency microtenotomy, Eccentric exercise, Arthrocare Topaz MicroDebrider
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- St Goran's Hospital
Amputation, Traumatic, Prosthesis User
Evaluation of a Non-invasive Sensory Feedback System in Hand Prostheses
Implication and evaluation of a non-invasive sensory feedback system in hand prostheses in everyday life.
- Trial name
- NCT03876405
- Testing
- smartskin non-invasive sensory feedback
- Volunteers
- 7 people
- Sponsor
- Lund University Hospital
Lateral Epicondylitis, Tennis Elbow
Prolotherapy for the Treatment of Chronic Lateral Epicondylitis
Lateral epicondylitis (LE), or tennis elbow, is a common and often disabling condition affecting young and middle-aged adults-most commonly manual workers and recreational athletes.
- Trial name
- NCT00674622
- Testing
- Prolotherapy
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Pittsburgh
Distal Radius Fracture
Effects of Early Manual Therapy on Functional Outcomes After Volar Plating of Distal Radius Fractures
The aim of the study was to investigate the effects of early manual therapy on function, pain, range of motion (ROM), hand and pinch grip strength and disability level in patients underwent volar plating after distal radius…
- Trial name
- NCT03613922
- Testing
- Early Manual Therapy, Routine Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Dokuz Eylul University
Tooth Avulsion, Dental Pulp Diseases
Optimizing Pulp Management in Autotransplantation of Mature Third Molars: A Randomized Controlled Trial
This study aims to find the best way to use your own healthy wisdom tooth to replace the bad tooth. After transplantation, how to manage the "tooth nerve" (dental pulp) inside the tooth is a key question.
- Conditions
- Tooth Avulsion, Dental Pulp Diseases, Tooth, Impacted
- Trial name
- OPuM-ATM3 (NCT07291531)
- Testing
- Postoperative Root Canal Therapy, Intraoperative Apical Surgery with Retrograde Filling, Intraoperative Root-End Resection
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Distal Radius Fracture
Immediate Mobilization Versus 2 Weeks Cast Immobilization After Distal Radius Fracture Treated With Volar Locking Plate
The aim of this study is to analyze total lenght of the sick leace and functional outcome (PRWE) at 2 months between 2 weeks casting and immediate mobilization following volar plating for a DRF.
- Trial name
- LIMPER-DRF (NCT05150925)
- Testing
- Cast treatment, Immediate mobilization, Volar plating
- Where
- 5 sites in Finland, Sweden
- Volunteers
- 240 people
- Sponsor
- Tampere University Hospital
Spinal Cord Injuries
Assessment of a Robotic Exoskeleton for Upper Limb Rehabilitation
Rehabilitation robotics has the potential to facilitate rehabilitation at home and empower people with spinal injuries to self-manage increasing their independence and improving their quality of life.
- Trial name
- Exo4UL (NCT05615766)
- Testing
- Experimental: Device Intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 9 people
- Sponsor
- University of Liverpool
Spinal Cord Injuries
Closed-loop Spinal Stimulation for Restoration of Upper Extremity Function After Spinal Cord Injury
The purpose of this study is to assess the efficacy of non-invasive (transcutaneous) closed-loop electrical spinal cord stimulation for recovery of upper limb function (Aim 1) and spasticity (Aim 2) following spinal cord injury.
- Trial name
- NCT05267951
- Testing
- Open-loop Stimulation, Close-loop Stimulation, Functional Task Practice
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Washington
Osteopenia, Osteoporosis
Extension Study to Evaluate the Long Term Safety and Efficacy of Denosumab in the Treatment of Osteoporosis
The primary objective was to describe the safety and tolerability of up to 10 years or 7 years denosumab administration as measured by adverse event monitoring, immunogenicity and safety laboratory parameters in participants who…
- Trial name
- NCT00523341
- Testing
- Denosumab
- Volunteers
- 4,550 people
- Sponsor
- Amgen
Lateral Epicondylitis
The Effect of Motor Learning Exercises on Lateral Epicondylitis
The aim of this study was to determine the effect of motor learning training in addition to a 6-week conventional physiotherapy program on motor imagery, function pain and grip strength in individuals with chronic lateral…
- Trial name
- NCT06459102
- Testing
- Motor Learning, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- KTO Karatay University
Pyoderma Gangrenosum
Efficacy of Bimekizumab in Adults With Pyoderma Gangrenosum
The purpose of the study is to learn more about an experimental drug bimekizumab that may be helpful for Pyoderma Gangrenosum (PG). Bimekizumab will be referred to as the study drug throughout this form.
- Trial name
- BEAT-PG (NCT07767864)
- Testing
- Bimekizumab
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Oregon Health and Science University
Athletic Injuries
Validity of an Upper Extremity Physical Performance Test Battery in Healthy Athletes
This project comprises two studies; a cross-sectional study and a prospective study. 1. The cross-sectional study aims to develop and validate a new sport-specific test battery (PROMs, analytical and physical performance tests)…
- Trial name
- VAL_PPT_H (NCT06153121)
- Testing
- Physical performance test - Closed Kinetic Chain Upper Extremity Stability Test (CKCUEST), Physical performance test - modified Closed Kinetic Chain Upper Extremity Stability Test (m-CKCUEST), Physical performance test - Seated Seated Single Arm Shot Put Test (SSASPT)
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Ghent
Degenerative Conditions of the Radial Head/Neck, Post-traumatic Conditions of the Radial Head/Neck
ExploR® Modular Radial Head Data Collection
The purpose of this prospective clinical data collection is to document the performance and clinical outcomes of the ExploR® Modular Radial Head. This data collection effort will document the clinical outcomes of the radial head.
- Trial name
- NCT00533234
- Testing
- ExploR® Modular Radial Head
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Biomet Orthopedics, LLC
Cervical Spinal Cord Injury
ExaStim Upper Limb Home Use Clinical Validation Study
This is a multi-center, observational, single-arm, 6-week home study to evaluate the safety and efficacy of transcutaneous spinal cord stimulation via the ExaStim system for 4 consecutive weeks used in the home setting for…
- Trial name
- NCT06850363
- Testing
- ExaStim Stimulation System
- Where
- 5 sites in United States
- Volunteers
- 33 people
- Sponsor
- Niche Biomedical, Inc. dba ANEUVO
Fracture Lower Leg, Fracture Dislocation of Upper Limb Joint
Relationship Between Mortality Rates of Fractures in Different Sites and Several Factors in Elderly Patients
Background and Purpose: As people age, bones become weaker and break more easily. Older adults (people 60 years and older) who break bones may face serious health problems and have a higher chance of dying compared to younger…
- Conditions
- Fracture Lower Leg, Fracture Dislocation of Upper Limb Joint, Spinal Fractures
- Trial name
- NCT07147504
- Volunteers
- 3,000 people
- Sponsor
- Shanghai 6th People's Hospital
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