Clinical trials: Upper Gastrointestinal Disorders
Laryngopharyngeal Reflux
Treatment of Extraesophageal Reflux With the Reza Band UES Assist Device
The purpose of the study is to determine the safety and effectiveness of non-invasive Reza Band UES Assist Device for the treatment of esophagopharyngeal reflux with extra-esophageal symptoms (chronic cough, choking, aspiration…
- Trial name
- NCT01857713
- Testing
- Reza Band UES Assist Device
- Where
- 5 sites in United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Somna Therapeutics, L.L.C.
Upper Gastrointestinal Disease, Duodenal or Gastric Ulcer.
Transnasal and Oral Gastroscopy.
Two groups of patients were randomised into two groups of either transnasal gastroscopy or conventional type gastroscopy (n=98).
- Trial name
- NCT00273117
- Testing
- transnasal gastroscopy
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Hvidovre University Hospital
Upper Gastrointestinal Bleeding
Use of PillCam ESO2 in Triaging Patients Present With Upper GIB
Background Patients presented to hospital with coffee ground vomiting and black stool may not be actually having upper gastrointestinal bleeding (UGIB) Hospital admission can be avoided if serious UGIB can be excluded To date…
- Trial name
- NCT02446678
- Testing
- PillCam ESO2
- Volunteers
- 68 people
- Sponsor
- Chinese University of Hong Kong
Esophageal Cancer
Trial of Enteral Nutrition Enriched With Eicosapentaenoic Acid (EPA) in Upper Gastrointestinal Cancer Surgery
This study aims to examine whether providing tube feeding with a formula enriched with omega-3 fats is better than traditional standard tube feeding in terms of preserving nutritional status, improving immune function and…
- Trial name
- NCT00790140
- Testing
- Prosure, Ensure Plus
- Where
- Ireland
- Volunteers
- 120 people
- Sponsor
- University of Dublin, Trinity College
Adults,Gastric Symptoms,Suspected Gastric Motility Disorders
Non-invasive Measurement of Gastric Motility
Clinical evaluation to compare performance of the physiological recordings from the Gastric Alimetry System vs a predicate reference device (Medtronic Polygram NET / Polygraf ID EGG System
- Trial name
- NCT04992884
- Testing
- Gastric Alimetry
- Where
- New Zealand
- Volunteers
- 25 people
- Sponsor
- Greg O'Grady
Upper Gastrointestinal Bleeding
OTSC vs. Angiographic Embolization in Patients With Refractory Non-variceal Upper Gastrointestinal Bleeding
In the management of patients with acute upper non-variceal upper gastrointestinal bleeding, further bleeding is the most important adverse factor predictive of mortality.
- Trial name
- NCT04902248
- Testing
- The OTSC® System Set, angiographic embolization
- Where
- 5 sites in China, Hong Kong and 1 more
- Volunteers
- 236 people
- Sponsor
- Chinese University of Hong Kong
Gastrointestinal Bleeding, Cirrhosis
Effects of the Administration of Ornithine Phenylacetate in Patients With Cirrhosis and Upper Gastrointestinal Bleeding
The main objective is to evaluate the effectiveness of the experimental drug to reduce plasma ammonia concentration at a dose that is safe and well tolerated.
- Trial name
- NCT01434108
- Testing
- Ornithine-phenylacetate
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Metastatic Colorectal Cancer
A Study Assessing Adverse Events and Disease Activity of Intravenously (IV) Infused Telisotuzumab Adizutecan in Adult Participants With c-Met Protein Above Cutoff Level Above Refractory Metastatic Colorectal Cancer
Colorectal cancer (CRC) is the third most common type of cancer diagnosed worldwide and in China. The purpose of this study is to assess adverse events and change in disease activity of intravenously (IV) infused telisotuzumab…
- Trial name
- NCT06614192
- Testing
- Telisotuzumab Adizutecan
- Where
- 51 sites in United States, Australia and 5 more
- Volunteers
- 74 people
- Sponsor
- AbbVie
Wasting, Undernutrition
Improvement of Nutrition Status, Digestive Conditions, and Upper Respiratory Infections by Using Oral Nutritional Supplementation on Children in Vietnam
Evaluating the efficiency of using the nutrient production toward nutrition status (anthropometric index, the prevalence of wasting), digestive disorders, anorexia, and upper respiratory infections in children aged 24 - 71 months.
- Conditions
- Wasting, Undernutrition, Malnourished, Malnutrition
- Trial name
- NCT05570045
- Testing
- Colos Gain
- Where
- Vietnam
- Volunteers
- 600 people
- Sponsor
- Tu Nguyen Song
Malignancy, Metastasis
Same-session MR-only Simulation and Treatment With MRI-guided Adaptive Palliative RadioTherapy
This proposed study is unique in that patients will not undergo computed tomography (CT) simulation at any point during their treatment course and will instead have same-session magnetic resonance (MR)-only simulation and…
- Conditions
- Malignancy, Metastasis, Hemoptysis, Gastrointestinal Bleeding
- Trial name
- MAP-RT (NCT03824366)
- Testing
- Volumetric MR imaging, Radiation therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Washington University School of Medicine
Cystic Fibrosis
Correction of Nonsense Mutations in Cystic Fibrosis
The presence of a nonsense mutation leads to the rapid degradation of the carrier mRNA mutation by a mechanism called NMD (nonsense-mediated mRNA decay) [6, 13].
- Trial name
- NCT03670472
- Testing
- smear of nasal fossae
- Where
- 8 sites in France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Lille
Gastroesophageal Reflux Disease
A Cross-sectional Study on the Prevalence and Extraesophageal Symptoms of Gastroesophageal Reflux Disease(GERD) in Patients With Upper GI Symptoms, Visiting the Outpatient Departments of Peripheral Hospitals in Greece
The present study has been designed to provide current data on GERD prevalence in several regional areas of Greece outside the two major urban centres (Athens and Thessaloniki), to measure the treatment response in GERD patients…
- Trial name
- GERDQ-XS (NCT01215305)
- Where
- 19 sites in Greece
- Volunteers
- 600 people
- Sponsor
- AstraZeneca
Gastric Cancer, Gastrectomy
Laparoscopic Spleen-Preserving No. 10 Lymph Node Dissection for AGC
The purpose of this study is to explore the safety and feasibility of laparoscopic spleen-preserving No. 10 lymph node dissection for patients with advanced middle or upper third gastric cancer.
- Conditions
- Gastric Cancer, Gastrectomy, Laparoscopic Surgery, Lymphadenectomy
- Trial name
- NCT03708783
- Testing
- laparoscopic Spleen-Preserving No. 10 Lymph Node Dissection
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Peking University Cancer Hospital & Institute
Pneumoperitoneum
Influence of Posture and Gas Insufflation on Perioperative Lung Function
Perioperative airway resistance and lung function are evaluated perioperatively in patients, who undergo surgical procedures in different postures and with or without gas insufflation into the peritoneal cavity.
- Trial name
- NCT00948571
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Kliniken Essen-Mitte
Upper Gastrointestinal Bleeding
ASP (PPI_H2RA) Study-H2RA Versus PPI for the Prevention of Recurrent UGIB in High-risk Users of Low-dose ASA
Peptic ulcer bleeding associated with ASA or NSAIDs is a major cause of hospitalization in Hong Kong. The investigators previously showed that ASA or NSAIDs accounted for about half of all cases of hospitalizations for peptic…
- Trial name
- NCT01408186
- Testing
- Rabeprazole, Famotidine
- Where
- 8 sites in Hong Kong, Japan
- Volunteers
- 264 people
- Sponsor
- Chinese University of Hong Kong
Upper Gastrointestinal Bleeding, Acute Kidney Injury
Acute Kidney Injury in Upper GI Bleeding Patients
This study aims to evaluate the incidence of acute kidney injury (AKI) among patients presenting with acute upper gastrointestinal bleeding (UGIB) at Sohag University Hospitals, and to identify predictors associated with renal…
- Trial name
- NCT07636083
- Testing
- Observational assessment
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Extrahepatic Bile Duct Cancer, Nausea
Aprepitant in Preventing Nausea and Vomiting in Patients Undergoing Chemotherapy and Radiation Therapy for Pancreatic Cancer
This pilot clinical trial is studying how well aprepitant works in preventing nausea and vomiting in patients undergoing chemotherapy and radiation therapy for pancreatic cancer.
- Conditions
- Extrahepatic Bile Duct Cancer, Nausea, Vomiting, Stage II Pancreatic Cancer
- Trial name
- NCT01534637
- Testing
- aprepitant, gemcitabine hydrochloride, capecitabine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University Health Sciences
Upper GI Bleeding
Inhalation of Sevoflurane Versus Intravenous Midazolam,Ketamine,Propofol For Pediatrics Undergoing Upper GI Endoscopy
In the field of pediatric gastroenterology, upper gastrointestinal endoscopy has established itself as a diagnostic and therapeutic tool. In order to increase patient tolerance during this procedure, deep sedation is essential.
- Trial name
- NCT05474937
- Testing
- Sevoflurane Inhalation Solution, Midazolam, Ketamine and Propofol
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Zagazig University
Gastrointestinal Bleeding
Efficacy of a Novel Hemostatic Powder in GI Bleeding
Hemospray™ is a new endoscopic hemostatic powder. Aims of this multicenter prospective study is to determine effectiveness of Hemospray™ on short and medium term in different clinical situations, predictive factors of rebleeding…
- Trial name
- GRAPHE (NCT02595853)
- Testing
- Non interventional study
- Where
- 19 sites in France, Monaco
- Volunteers
- 200 people
- Sponsor
- Nantes University Hospital
Migraine Headache, Gastric Diseases
Effect of "Sekanjabin e Safarjali" (Quince Oxymel) in the Prevention of Migraine Attacks
The purpose of this study is to determine whether Quince Oxymel is effective in the prevention of Migraine attacks in patients with simultaneous upper gastrointestinal dysfunction.
- Trial name
- NCT02179775
- Testing
- propranolol, Quince's oxymel
- Where
- 2 sites in Iran
- Volunteers
- 45 people
- Sponsor
- Shiraz University of Medical Sciences