Clinical trials: Upper Gastrointestinal Hemorrhage
Upper Gastrointestinal Hemorrhage
A Pilot and Feasibility Study to Evaluate Capsule Endoscopy
This study is aimed at assessing the capability of the PillCam Platform using the PillCam ESO 2 Capsule in: Determining whether there is 1) active bleeding in the Upper gastrointestinal (UGI) tract, 2) identifying the anatomic…
- Trial name
- MA-79 (NCT00974701)
- Testing
- PillCam ESO2
- Where
- 2 sites in Hong Kong, Israel
- Volunteers
- 50 people
- Sponsor
- Medtronic - MITG
Upper GI Bleeding, Point of Care Ultrasound
Bedside Ultrasonic Assessment for Gastric Content in Patients With Upper GI Bleeding Undergoing Endoscopy
Emerging studies have evaluated POCUS (Point of Care Ultrasound) for assessing of gastric content prior to anesthesia to reduce the risk of aspiration and demonstrated that POCUS can accurately identify presence of gastric food…
- Conditions
- Upper GI Bleeding, Point of Care Ultrasound, Upper Endoscopy, Gastric Content
- Trial name
- NCT05763745
- Testing
- Point of Care Ultrasound
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Loma Linda University
Gastrointestinal Endoscopy, Upper Gastrointestinal Hemorrhage
TEAS for Variceal Bleeding Endoscopy in Cirrhosis
This randomized controlled trial evaluates whether transcutaneous electrical acupoint stimulation (TEAS) improves procedural success and patient tolerance in cirrhotic patients undergoing urgent unsedated endoscopy for suspected…
- Conditions
- Gastrointestinal Endoscopy, Upper Gastrointestinal Hemorrhage, Variceal Bleeding, Cirrhosis
- Trial name
- TEAS-VBE-C (NCT07106658)
- Testing
- TEAS + Urgent Endoscopy, Urgent Endoscopy Only
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Beijing 302 Hospital
Upper Gastrointestinal Bleeding
Randomized Trial of Outpatient vs. Inpatient Management of Low-risk Patients With Upper Gastrointestinal Bleeding.
Patients presenting to the emergency room with upper gastrointestinal bleeding and a Glasgow Blatchford score of zero will be randomly assigned to further care in the inpatient vs. outpatient setting.
- Trial name
- NCT02005705
- Testing
- Outpatient Management of Low-risk Patients, Inpatient Management of Low-risk Patients
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Yale University
Cirrhosis, Liver, Acute Upper Gastrointestinal Hemorrhage
Risk Assessment After Acute Upper Gastrointestinal Haemorrhage in Cirrhosis
In previous studies, the investigators used retrospective analysis of cases of acute upper gastrointestinal bleeding in patients with liver cirrhosis from the Fifth Medical Center of the General Hospital of Beijing PLA, China…
- Trial name
- NCT04235166
- Testing
- Current risk scores, New risk scores
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Anticoagulants and Bleeding Disorders, Gastrointestinal Hemorrhage
Comparison of the Effect of Warfarin and Direct Oral Anticoagulants
In this study, it was aimed to compare the frequency of new oral anticoagulants and warfarin usage, and to reveal the rates of recurrent upper gastrointestinal bleeding among patients who applied to our hospital with upper…
- Trial name
- NCT06269302
- Where
- Turkey (Türkiye)
- Volunteers
- 346 people
- Sponsor
- Samsun Education and Research Hospital
Upper Gastrointestinal Bleeding
Trial of Hemospray Plus Epinephrine Injection Versus Endoscopic Hemoclip
The non-variceal upper gastrointestinal bleeding is defined as gastrointestinal bleeding located proximal to the angle of Treitz, whose cause is not related to esophagogastric varices or gastropathy of portal hypertension.
- Trial name
- NCT02537353
- Testing
- Metal clips, Hemospray, Endoscopy Exam
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Hemorrhage, Hemorrhagic Shock
Optimization Strategies for Blood Transfusion Protocols in the Emergency Treatment of Hemorrhagic Shock
This single-center, prospective, randomized controlled trial was approved by the institutional ethics committee and overseen by an independent data and safety monitoring board.
- Conditions
- Hemorrhage, Hemorrhagic Shock, Upper Gastrointestinal Bleeding (UGIB)
- Trial name
- NCT07129031
- Testing
- low-titer O-group whole blood, 1:1:1 component transfusion, ABO- and Rh-compatible whole blood
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Xijing Hospital
Peptic Ulcer Hemorrhage, Peptic Ulcer, Acute With Hemorrhage
Registry for Upper Gastrointestinal Bleeding
This project aims to evaluate the data on all patients undergoing endoscopic therapy for upper gastrointestinal bleeding.
- Trial name
- NCT04211194
- Testing
- Upper GI Endoscopy
- Where
- United States
- Volunteers
- 2,999 people
- Sponsor
- AdventHealth
Acute Gastrointestinal Bleeding
Safety and Efficacy of Prophylactic Arterial Embolization in the Treatment of Angiography-negative Acute Upper Gastrointestinal Bleeding
Guided by clinical problems, this study focused on the problems encountered in clinical practice, with the interventional treatment of emergency gastrointestinal bleeding as the breakthrough point, and focused on the dilemma of…
- Trial name
- NCT05550649
- Testing
- embolization
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai 10th People's Hospital
UGI Bleed, Upper Gastrointestinal Bleeding
PillSense System for Detecting UGI Bleed
This is a prospective, non-randomized, open-label clinical investigation to evaluate feasibility, effectiveness and safety of the PillSense System, the transit of the PillSense Capsule through the GI tract, patient tolerability…
- Conditions
- UGI Bleed, Upper Gastrointestinal Bleeding, Upper Gastrointestinal Bleed
- Trial name
- NCT05385224
- Testing
- PillSense
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- EnteraSense Limited
Gastrointestinal Bleeding
Early Endoscopy for Acute Upper Gastrointestinal Bleeding in Acute Coronary Syndrome Patients
The primary aim of this study is to compare efficacy of "early endoscopy" and "non-endoscopic treatment" for management of acute upper gastrointestinal (UGI) bleeding in patients with recent acute coronary syndrome (ACS).
- Trial name
- NCT02618980
- Testing
- endoscopic hemostasis
- Where
- Taiwan
- Volunteers
- 43 people
- Sponsor
- Far Eastern Memorial Hospital
Coronary Disease
Cardiovascular Events in Patients With CAD During Emergent Endoscopy for Upper Gastrointestinal Bleeding
Background: Upper gastrointestinal (GI) bleeding, a common disorder encountered at emergency room, may cause hypotension and tachycardia that may in turn result in myocardial ischemia in patients with coronary artery disease…
- Trial name
- NCT00173511
- Testing
- 24 hr Holter monitor
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Upper Gastrointestinal Hemorrhage
Risk Scoring Systems in Upper GI-haemorrhage
Use of risk scoring systems in the assessment of patients presenting with upper gastrointestinal haemorrhage is increasing. Comparative studies have intended to identify the system of choice, but the majority of these are…
- Trial name
- NCT01589250
- Where
- Denmark
- Volunteers
- 831 people
- Sponsor
- Odense University Hospital
UGI Bleed
A Prospective Pilot Study to Evaluate the Diagnostic Performance of a Wireless Sensor Capsule in Detection of UGIB
It is a single-center, prospective study, which will be conducted in a tertiary academic hospital (Prince of Wales Hospital). All subjects will undergo a paired examination of HemoPill® acute capsule and…
- Trial name
- HemoPill (NCT06409182)
- Testing
- Hemopill
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
UGI Bleed
Comparison of Risk Scores in Upper Gastrointestinal Bleeding
The goal of this prospective observational study is to compare the Glasgow-Blatchford Score (GBS), AIMS65, and pre-endoscopic Rockall Score in predicting outcomes among patients with upper gastrointestinal bleeding (UGIB).
- Trial name
- NCT07819942
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Kathmandu Medical College and Teaching Hospital
Intubation;Difficult, Gastrointestinal Bleeding
Evaluation of Prophylactic Endotracheal Intubation
Upper gastrointestinal (GI) bleeding is defined as patients who either presented with hematemesis or presented with melena along with evidence of hemodynamic compromise.
- Trial name
- NCT03716466
- Testing
- Endotracheal intubation, No airway intervention
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Texas Southwestern Medical Center
Non-variceal Upper Gastrointestinal Bleeding
Effects of Different Omeprazole Dosing on Gastric pH in Non-variceal Upper Gastrointestinal Bleeding
The aim of the study is to identify the best method of omeprazole (OME) application with respect to intragastric pH, cytochrome P450 2C19 (CYP2C19) genotype and phenotype.
- Trial name
- NCT03980496
- Testing
- Omeprazole
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Bialystok
Ischemic Stroke, Transient Ischemic Attack
Zastaprazan for the prEvention of Upper GI Bleeding in Ischemic Stroke
The goal of this clinical trial is to learn if zastaprazan can help prevent upper gastrointestinal bleeding in adults who have recently had a transient ischemic attack (TIA) or ischemic stroke and are taking antiplatelet or…
- Trial name
- NCT07730840
- Testing
- Zastaprazan
- Where
- 15 sites in South Korea
- Volunteers
- 984 people
- Sponsor
- Asan Medical Center
Upper Gastrointestinal Bleeding, Cirrhosis
Transfusion Requirements in Gastrointestinal (GI) Bleeding
Recently it has been suggested that a restrictive transfusion of units of Red Cells (URC) may improve the outcome of ICU patients with anemia.
- Conditions
- Upper Gastrointestinal Bleeding, Cirrhosis, Portal Hypertension
- Trial name
- NCT00414713
- Testing
- red blood cell transfusion
- Where
- Spain
- Volunteers
- 860 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau