Clinical trials: Upper Limb Amputees
Amputation, Surgical
Improving Prosthetic Arms for Amputee: A Better Fit and More Functionality
This research and development will improve upon and investigate the potential validity of an innovative new transradial socket and harness design (the KSH system) that offers an alternative to standard hard sockets and rubber…
- Trial name
- KSH (NCT05990062)
- Testing
- K-Socket-Harness
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Bilateral Upper Limb Amputation, Transverse Short Amputation of the Hand
Bilateral Upper Limb Amputation Observatory
In France, there is currently no data to directly estimate the number of bilateral upper limb amputations, their characteristics and therapeutic care.
- Conditions
- Bilateral Upper Limb Amputation, Transverse Short Amputation of the Hand, Arm Amputation
- Trial name
- ARMOBS (NCT02835378)
- Testing
- No intervention
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Behavior, Amputation
Self-Management for Amputee Rehabilitation Using Technology.
Lower Limb Amputations (LLAs) are a substantial burden on the Canadian health services with nearly 50,000 cases reported between 2006 and 2011.
- Conditions
- Behavior, Amputation, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury)
- Trial name
- SMART (NCT04953364)
- Testing
- SMART, Control
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Amputation, Amputation; Traumatic, Hand
Dexterous Partial Hand Prosthesis Outcomes
Liberating Technologies, Inc. (LTI) has developed a dexterous prosthetic fingertip that will be fit onto an i-Digits™ partial hand prosthesis and allow for an additional fine grasp.
- Conditions
- Amputation, Amputation; Traumatic, Hand, Limb; Absence, Congenital, Upper, Prosthesis User
- Trial name
- NCT05038566
- Testing
- Pointdexter
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Amputation, Traumatic, Limb Defect
Assessing Force Feedback With the SoftHand Pro
The trial is designed to test the effectiveness of a force-feedback cuff in combination with a myoelectric prosthesis in conveying information on grasp strength to the user, as well as the user's preference regarding the feature.
- Trial name
- CUFF (NCT03412656)
- Testing
- SoftHand Pro with CUFF force feedback device
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Kristin Zhao, PhD
Amputation, Amputation; Traumatic, Leg, Lower
Clinical Outcomes With Non-Powered vs. Powered Prosthetic Knees by K2-level Amputees
The goal of this proposed project is to gather community-based data from the K2-level Transfemoral Amputee (TFA) population to aid in evidence-based prescription of powered prosthetic knees (i.e., choosing the right device to…
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User
- Trial name
- NCT06194838
- Testing
- Ossur Power Knee, Reboocon Intuy Knee
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Liberating Technologies, Inc.
Amputation, Congenital, Upper Limb; Amelia
CNS Changes Following Upper Limb Loss
The objective of this study is to better understand the structural and functional changes that the central nervous system (CNS) undergoes following congenital upper limb loss.
- Trial name
- NCT06043518
- Testing
- MRI
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Phantom Limb, Residual Limb Pain
Acupuncture for the Treatment of Phantom Limb and Residual Limb Pain After Amputation
The purpose of this study is to identify the best treatment sequence and combination of acupuncture points for the treatment of phantom limb or residual limb pain in the traumatic/surgical amputee.
- Conditions
- Phantom Limb, Residual Limb Pain, Traumatic Amputation, Amputation
- Trial name
- NCT00388752
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Walter Reed Army Medical Center
Amputation
Enhanced Tactile (Touch) Spatial Acuity in Upper Limb Amputees
This study will examine whether tactile (touch) abilities at the lip are more acute in people with upper limb amputation compared with healthy normal volunteers.
- Trial name
- NCT00028210
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Phantom Limb Pain
Comparison of Efficacy of Mirror Therapy vs Mental Imagery in Reduction of Phantom Limb Pain in AKAP
Limb amputation results in many types of pain, including localized pain at the stump and projected pain experienced by the patient in the location where the amputated limb used to be, known as phantom limb pain (PLP).
- Trial name
- NCT06428123
- Testing
- Mirror Therapy on present Lower Limb, Mental Imagery on present Lower Limb
- Where
- 2 sites in Pakistan
- Volunteers
- 24 people
- Sponsor
- Superior University
Prosthesis Migration, Amputation
Evaluation of the Stability of Osseointegrated Implant in Amputees
The study concerns the technique of osseointegration that consists of inserting a titanium pin into the bone of the amputated limb.
- Trial name
- METACOS (NCT03836755)
- Testing
- Metacos
- Where
- Italy
- Volunteers
- 4 people
- Sponsor
- Istituto Ortopedico Rizzoli
Transfemoral Amputation, Limb Loss
A Biomechanical Evaluation of the Ossur Power Knee in Persons With Transfemoral Amputation
Microprocessor-controlled knees (MPKs) do not typically utilize motors to power joint rotation, but they automatically adjust resistance or damping in the joint to improve swing- and/or stance-phase control as appropriate for the…
- Conditions
- Transfemoral Amputation, Limb Loss, Limb Absence
- Trial name
- OPKTFA (NCT06218238)
- Testing
- Powered prosthetic knee joint, Conventional microprocessor-controlled prosthetic knee joint
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Transfemoral Amputation
Assessment of Strength, Balance, and Function in Above-Knee Amputees in Relation to Residual Limb Length
The goal of this observational study is to learn how muscle strength, balance, and functional ability are affected in people with above-knee (transfemoral) amputations.
- Trial name
- NCT07032233
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Ceren Kuzu
Amputation
Enhanced Auto-Diagnostic Adaptive Precision Trainer for Myoelectric Prosthetic Users
The eADAPT training consists of a variety of mobile games played on a mobile app (phone or tablet). A band is worn on the residual limb. Participants use muscle activation to send signals to execute certain movements in the game.
- Trial name
- eADAPT (NCT04238533)
- Testing
- eADAPT training, Conventional training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Phantom Limb Pain, Phantom Pain
VR to Evaluate Phantom Limb Pain
The objective of this study is to develop a virtual rehabilitation system that can be used to effectively treat Phantom Limb Pain (PLP) within the research setting and for at-home use by individuals with upper and lower extremity…
- Conditions
- Phantom Limb Pain, Phantom Pain, Phantom Sensation, Phantom Limb Syndrome With Pain
- Trial name
- NCT05915065
- Testing
- Coapt Phantom Limb Pain Management System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Lower Limb Amputation Above Knee (Injury)
Decoding Motion Planning Using Cortical Potentials
The team will investigate the user's intention to move by using cortical activity during a sit to stand movement performance in people with a transfemoral amputation and able-bodied individuals.
- Trial name
- NCT04325516
- Testing
- Daily activities
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Upper Limb Amputation, Healthy Subjects
Microneurography and Intraneural Microstimulation for Upper Limb Sensory Investigation in Healthy and Amputee Subjects
The goal of this experimental study is to investigate the somatosensory system through intraneural recording and stimulation of the median nerve in healthy volunteers and participants with upper-limb amputation.
- Trial name
- MICROAMP (NCT07691957)
- Testing
- Microneurography, Intraneural Microstimulation
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Amputation, Amputation, Traumatic
Neuromusculoskeletal Interface for Bionic Arms
The overall objective of this proposal is to perform a first-in-human home trial of the Electronic Osseoanchored Prostheses for the Rehabilitation of Amputees (e-OPRA) implant system in individuals with transhumeral amputations…
- Conditions
- Amputation, Amputation, Traumatic, Amputation, Surgical, Upper Limb Amputation Above Elbow (Injury)
- Trial name
- NCT07032753
- Testing
- eOPRA, OPRA, eOPRA with sensory feedback
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shirley Ryan AbilityLab
Amputation, Amputation, Traumatic
Evaluation of Dexterous Terminal Device
Liberating Technologies, Inc. (LTI) has developed Pointdexter, a dexterous prosthetic fingertip that is integrated into a commercial prosthetic hand and allows for an additional fine grasp.
- Conditions
- Amputation, Amputation, Traumatic, Amputation; Traumatic, Hand, Limb; Absence, Congenital, Upper
- Trial name
- NCT05840601
- Testing
- Pointdexter, Comparator
- Sponsor
- Liberating Technologies, Inc.
Amputation, Upper Limb
A Patient-Driven Augmented Reality-Based Rehabilitation System to Improve Upper Limb Amputee Outcomes
The investigators propose to evaluate the efficacy of MyoTrain AR in a prospective clinical study involving 10 individuals with trans-radial upper-limb loss over a period of 35 days.
- Trial name
- NCT05975970
- Testing
- MyoTrain AR, Motor Imagery
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Infinite Biomedical Technologies