Clinical trials: Upper Limb Dysfunction
Neck Pain, Upper Extremity Dysfunction
Unsupported Upper Extremity Exercise Test in Chronic Neck Pain
The aim of this study was to examine the validity and test-retest reliability of unsupported upper extremity exercise test (UULEX) in individuals with chronic neck pain.
- Trial name
- NCT04937985
- Testing
- Performance Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Izmir Katip Celebi University
Upper Limb Motor Dysfunction, Stroke
ZEPU-SGI1PLUS Hand Training Study (ZEPUSGI1RCT)
The goal of this pilot randomized controlled trial is to learn whether the ZEPU-SG1PLUS Hand Functional Comprehensive Training System - a robotic device used alongside standard rehabilitation - is safe, feasible, and helpful for…
- Conditions
- Upper Limb Motor Dysfunction, Stroke, Incomplete Spinal Cord Injury, Traumatic Brain Injury
- Trial name
- NCT07739264
- Testing
- ZEPU-SG1PLUS Hand Functional Comprehensive Training System, Standard-of-Care Rehabilitation
- Where
- Bangladesh
- Volunteers
- 36 people
- Sponsor
- Bangladesh Medical University
Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric)
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
Researchers are looking for a better way to treat children and young adults who have heart failure with left ventricular systolic dysfunction (LVSD).
- Trial name
- FIORELLO (NCT07192952)
- Testing
- Finerenone (Kerendia, BAY94-8862)
- Where
- 132 sites in United States, Argentina and 21 more
- Volunteers
- 117 people
- Sponsor
- Bayer
Stroke, Parkinson Disease
PhiCube for Bilateral Upper Limb Neuromotor and Cognitive Rehabilitation in Adults
This randomized controlled pilot trial evaluates the usability and safety of PhiCube, a compact, portable, bilateral end-effector robotic device for upper limb rehabilitation, and its impact on motor and cognitive function.
- Conditions
- Stroke, Parkinson Disease, Amyotrophic Lateral Sclerosis, Spinal Cord Injuries
- Trial name
- PhiCube-Adults (NCT07865260)
- Testing
- PhiCube, Conventional rehabilitation
- Where
- 4 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato
Breast Cancer, Upper Extremity Dysfunction
Exercise Rehabilitation Via a Mobile Application for Individuals With Breast Cancer Undergoing Chemotherapy
The primary purpose of this study is to determine the feasibility of our proposed intervention approach involving (1) an integrated physiotherapy and exercise intervention for individuals with breast cancer who are undergoing…
- Trial name
- Empower (NCT05254678)
- Testing
- general exercise
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Alberta
Stroke, Upper Extremity Dysfunction
Dual Channel Rehabilitation Technology Promotes Rapid Recovery of Upper Limbs After Stroke
The injury and remodeling mechanism about upper extremity motor network after stroke is not clear. There are few studies on the motor network covering cortex, white matter and blood perfusion at the time.
- Conditions
- Stroke, Upper Extremity Dysfunction, Transcranial Direct Current Stimulation, Image, Body
- Trial name
- NCT04944680
- Testing
- Transcranial Direct Current Stimulation therapy, Motor imagery therapy, Transcranial Direct Current Stimulation and motor imagery therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Elbow Fracture, Stiffness of Elbow, Not Elsewhere Classified
The Turkish Version of the Shanghai Elbow Dysfunction Score
The Shanghai Elbow Dysfunction Score (SHEDS) is originally developed in English to evaluate elbow function in patients with elbow stiffness.
- Conditions
- Elbow Fracture, Stiffness of Elbow, Not Elsewhere Classified, Orthopedic Disorder, Assessment, Self
- Trial name
- NCT04872205
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Istanbul University - Cerrahpasa
Stroke
Motor-Cognitive Interactive Upper Limb Robot Rehabilitation for Post-Stroke Motor Dysfunction
This study aims to investigate the effects of motor-cognitive interactive robot-assisted training on improving upper limb motor dysfunction after stroke.
- Trial name
- NCT06876597
- Testing
- Motor-cognitive interactive robot, Motor-focused robot, Conventional rehabilitation training
- Where
- China
- Volunteers
- 1,047 people
- Sponsor
- Lidian Chen
Erectile Dysfunction, Metabolic Syndrome
Lifestyle Modification for Erectile Dysfunction in Men With Metabolic Syndrome
Metabolic syndrome is associated with erectile dysfunction through obesity, insulin resistance, abnormal blood lipids, high blood pressure, and impaired blood-vessel function.
- Trial name
- LIFE-MetS-ED (NCT07758842)
- Testing
- Structured Lifestyle Modification Program
- Where
- 2 sites in Egypt
- Volunteers
- 55 people
- Sponsor
- Al-Azhar University
Glioblastoma, Radiotherapy; Complications
Testing Ramipril to Prevent Memory Loss in People With Glioblastoma
This study is to determine if an oral drug called Ramipril can lower the chance of memory loss in patients with glioblastoma getting chemoradiation.
- Conditions
- Glioblastoma, Radiotherapy; Complications, Cognitive Decline, Chemoradiation
- Trial name
- NCT03475186
- Testing
- Ramipril
- Where
- 423 sites in United States, Guam
- Volunteers
- 75 people
- Sponsor
- Wake Forest University Health Sciences
Upper Extremity Dysfunction
Kendall Exercises Versus Proprioceptive Neuromuscular Facilitation Technique in Patients With Upper Cross Syndrome
Upper Crossed Syndrome (UCS) is a postural disorder characterized by a distinct pattern of muscle imbalances within the musculature of the shoulder girdle and cervico-thoracic region.
- Trial name
- NCT06770205
- Testing
- traditional physical therapy, kendall Exercise Group A
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Riphah International University
Stroke
Virtual Reality's Impact on Upper Limb Function in Post-stroke Patients
Stroke rank second among the top causes of death, affecting millions of people in the worldwide. Approximately 70-80% survivors of stroke could experience various levels of upper limb motor impairments, which seriously affects…
- Trial name
- NCT06881680
- Testing
- virtual reality (VR) head mounted display
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Qilu Hospital of Shandong University
Male Erectile Disorder, Prostate Cancer
Focal Therapy for Prostate Cancer Using HIFU
RATIONALE: Prospective trials using hemi-ablation with high intensity focused ultrasound (HIFU) (Sonablate 500) have demonstrated feasibility, safety, and encouraging functional outcomes and early cancer control with 90% of men…
- Conditions
- Male Erectile Disorder, Prostate Cancer, Therapy-related Toxicity, Urinary Incontinence
- Trial name
- INDEX (NCT01194648)
- Testing
- questionnaire administration, assessment of therapy complications, high-intensity focused ultrasound ablation
- Where
- United Kingdom
- Volunteers
- 354 people
- Sponsor
- University College, London
Aortic Valve Disease, Mitral Valve Disease, Prosthetic Heart Valve Dysfunction, Valvular Heart Disease Requiring Surgical Aortic or Mitral Valve Replacement
Safety and Performance of Dafodil Heart Valves in Real-World Aortic and Mitral Valve Replacement
This study, called the EuroDafodil Registry, is being conducted to understand how safe and effective the Dafodil™ and Dafodil Neo™ Pericardial Bioprosthetic heart valves are when used in routine medical practice.
- Trial name
- NCT07379112
- Testing
- Dafodil™ / Dafodil Neo™ Pericardial Bioprosthetic Heart Valve
- Volunteers
- 500 people
- Sponsor
- Meril Life Sciences Pvt. Ltd.
Stroke
The Impact of App-based Cognitive Training on Post-stroke Upper Extremity Rehabilitation
To find out the impact of app-based cognitive training on upper extremity function in patients with sub-acute stroke.
- Trial name
- NCT05951530
- Testing
- traditional physical therapy, mobile app-based cognitive training
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Stroke, Spasticity, Muscle
REHABOTICS: Integrated Rehabilitation System for People With Motor Disabilities
The goal of the Rehabotics project is the development of a comprehensive rehabilitation system to provide highly individualized treatment of upper limb function in patients with motor disorders due to acquired brain damage (eg…
- Conditions
- Stroke, Spasticity, Muscle, Upper Extremity Dysfunction
- Trial name
- NCT06519630
- Testing
- Rehabotics Physiotherapy, Traditional Physiotherapy
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Pantelis Syringas
Organ Transplantation, Liver Dysfunction
Normothermic Oxygenated Perfusion (NMP) Viability Testing Before Transplantation of Discarded Livers
Liver transplantation (LT) is a highly effective treatment for end-stage liver disease and early-stage primary liver cancer. As such, the demand for donor livers greatly exceeds supply; in 2021 in France, 12.9% of patients on the…
- Conditions
- Organ Transplantation, Liver Dysfunction, Liver Diseases
- Trial name
- TRANSPERF (NCT06950398)
- Testing
- NMP viability testing
- Where
- 6 sites in France
- Volunteers
- 99 people
- Sponsor
- Rennes University Hospital
Upper Extremity Dysfunction
Effects of Different Stimuli on Muscle Activation, Hand Grip Strength, Reaction Time, and Hand Function
The study will include three separate intervention groups: an ice application group, a vibration application group, and a control group. Accordingly, three groups were randomly generated using the Research Randomizer software.
- Trial name
- NCT07407114
- Testing
- Ice, Vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Hemiplegia, Upper Extremity Dysfunction
Evaluation of the Effects of Neuromuscular Electrical Stimulation and Mirror Therapy in Hemiplegia Rehabilitation
In this study, it was aimed to evaluate whether or not NMES in front of the mirror brings an additional benefit to mirror therapy alone or NMES alone on upper extremity motor and functional development, spasticity, anxiety…
- Trial name
- NCT04913506
- Testing
- Group Mirror, Group NMES, Group Mirror+NMES
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Stroke
Treatment of Hand Dysfunction After Stroke
Many stroke survivors exhibit persistent upper limb motor deficits and a non-functional upper limb. There is some promising information that suggests motor learning (ML) in conjunction with functional electrical stimulation (FES…
- Trial name
- NCT00508521
- Testing
- Functional Electrical Stimulation, Standard Care
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- US Department of Veterans Affairs