Clinical trials: Upper Limb Function, active
Distal Radius Fracture, Clavicle Fracture
Digital Aftercare for Wrist and Clavicle Fractures
This prospective, two-arm, open-label clinical trial compares digital aftercare with traditional follow-up in adult patients after surgical treatment of uncomplicated distal radius or clavicle fractures.
- Conditions
- Distal Radius Fracture, Clavicle Fracture, Postoperative Care, Patient-Reported Outcome Measures (PROMs)
- Trial name
- DA-DRAC (NCT07055139)
- Testing
- Digital Aftercare, Traditional Aftercare
- Where
- Switzerland
- Volunteers
- 84 people
- Sponsor
- Luzerner Kantonsspital
Metastatic Gastroesophageal Junction Adenocarcinoma
Fruquintinib in Combination With Sintilimab and CAPEOX as First-line Treatment for G/GEJ Cancer
Based on the current status and progress in the treatment of gastric cancer, our center prospectively designed a first-line comprehensive treatment plan for unresectable or postoperative recurrent advanced…
- Trial name
- NCT06329973
- Testing
- Fruquintinib in combination with Sintilimab and CAPEOX
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Henan Cancer Hospital
Cerebral Palsy, Spastic
Effect of Task-Specific Training in an Augmented Reality Context on Upper Limb Function and Activities in Children With Spastic Cerebral Palsy
Children with Cerebral Palsy (CP), a condition that affects movement and coordination, face difficulties in daily activities such as dressing, reaching for objects in high places, and getting up from seats.
- Trial name
- INTERACT (NCT06571929)
- Testing
- INTERACT
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Gastric Cancer (GC), Stomach Neoplasms
TEAS Timing for Gastrectomy Recovery (TEAS-TIME Trial)
The goal of this clinical trial is to learn if transcutaneous electrical acupoint stimulation (TEAS) works to help people recover faster after laparoscopic surgery for stomach cancer.
- Trial name
- NCT07714980
- Testing
- Transcutaneous Electrical Acupoint Stimulation
- Where
- 13 sites in China
- Volunteers
- 300 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Spinal Cord Injuries (SCI), Upper Limb Function
Investigating the Upper Limb During the First 6 Months After Sustaining a Cervical Spinal Cord Injury,
The goal of this observational study is to investigate and describe the injury patterns, secondary complications, and biomechanical properties of the upper limb during the initial 6 months post-SCI.
- Trial name
- In Ul 6 SCI (NCT06740279)
- Testing
- Assessment of upper limb function
- Volunteers
- 210 people
- Sponsor
- Vastra Gotaland Region
Stroke, Hemiplegia
The Effect of Modified Constraint Induced Movement Therapy on Upper Extremity Function in Stroke Rehabilitation
The purpose of the study is to determine the effect of Modified Constraint-Induced Movement Therapy and trunk restraint contrasted with conventional physical therapy treatment on improving upper extremity function, balance, and…
- Conditions
- Stroke, Hemiplegia, Chronic Stroke Patients
- Trial name
- mCIMT (NCT06692569)
- Testing
- Conventional Physical Therapy, Modified Constraint Induced Movement Therapy
- Where
- Saudi Arabia
- Volunteers
- 34 people
- Sponsor
- University of Jazan
Peritoneal Dialysis Complication, End Stage Kidney Disease
meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsis
The primary aim of this study is to determine the safety and mechanisms of SGLT2 inhibition in individuals on peritoneal dialysis (PD) with residual kidney function (RKF).
- Conditions
- Peritoneal Dialysis Complication, End Stage Kidney Disease, Sodium-glucose Co-transporter-2 Inhibitors, Kidney Dysfunction
- Trial name
- CANARY (NCT05715814)
- Testing
- Empagliflozin 25 MG
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Breast Cancer Female
Body Awareness, Upper Extremity Function, and Quality of Life in Breast Cancer Survivors
Breast cancer is one of the most common types of cancer among women and one of the leading causes of morbidity and mortality. With increasing survival rates, issues such as treatment-related morbidities and consequently upper…
- Trial name
- NCT07133087
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Halic University
Amputation, Amputation, Traumatic
GaMA Metric to Quantify Functional Importance of Various Upper Limb Prosthetic Devices
The goal of this study is to utilize the Gaze and Movement Assessment (GaMA) metric to assess the effect of different prosthetic components on compensatory movements used to complete activities of daily living.
- Conditions
- Amputation, Amputation, Traumatic, Amputation; Traumatic, Hand, Amputation; Traumatic, Limb
- Trial name
- NCT06420687
- Testing
- Clinically prescribed prosthesis, Experimental prosthesis - Wrist rotation + 1-DOF, Experimental prosthesis - Wrist rotation + Wrist flexion +1-DOF
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Chronic Stroke
Personalized Transcranial Direct Current Stimulation in Stroke Recovery
The central objective of this application is to explore the neural substrate of personalized tDCS (ptDCS) and to determine whether the paradigm for each stroke patient can predict the amount of sustained clinical improvement…
- Conditions
- Stroke, Chronic Stroke, Hemorrhage Brain, Ischemic Stroke
- Trial name
- NCT06286800
- Testing
- Transcranial direct current stimulation (tDCS) with OT
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The Methodist Hospital Research Institute
Cerebral Palsy
Intensive Bimanual Intervention in Cerebral Palsy Children
Motor disorders related to cerebral palsy are often accompanied by sensory, cognitive, perceptive, communication and behavioural impairments.
- Trial name
- NCT05423171
- Testing
- Intensive bimanual therapy
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Stroke
Effects of Task-Based Mirror Therapy for Post-stroke Shoulder-Hand Syndrome
The study aims to determine the effects of task-based mirror therapy on edema, pain and upper limb motor function with shoulder-hand syndrome in post stroke patients.
- Trial name
- NCT07428811
- Testing
- Task based mirror therapy, Conventional exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Bleeding Disorders, Iron
Impact of IV Iron on Bleeding Symptoms in Iron Deficient Patients With Inherited Bleeding Disorders
This is a prospective, single-arm, single-center observational study evaluating the impact of intravenous (IV) iron replacement in patients with inherited bleeding disorders and iron deficiency (ferritin <50ng/dL).
- Conditions
- Bleeding Disorders, Iron, Platelet, Bleeding
- Trial name
- IRON-BD (NCT07083583)
- Testing
- IV Iron (standard of care)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nicoletta C Machin
Distal Radius Fracture
Effect of Whole Body Vibration on Rehabilitation in Distal Radius Fractures
This study is a randomized controlled clinical trial designed to evaluate the effects of whole body vibration (WBV) added to conventional rehabilitation on functional and sensorimotor recovery in patients with conservatively…
- Trial name
- WBV-DRF (NCT07723456)
- Testing
- Whole-Body Vibration Therapy, Conventional Rehabilitation Exercise Program
- Volunteers
- 66 people
- Sponsor
- Istanbul University
Distal Radius Fracture, Kinesiophobia
The Investigation of Kinesiophobia in Conservative Distal Radius Fractures
This study aimed to investigate the predictability of kinesiophobia on functional outcomes in conservatively treated patients with distal radius fractures.
- Conditions
- Distal Radius Fracture, Kinesiophobia, Functional Status
- Trial name
- NCT07291505
- Testing
- Questionnaire and Physical Exam
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Pamukkale University
Peripheral Arterial Disease
Local or Systemic Effects: Mechanisms Related to Arm Crank Exercise - Comparison Between Individuals With and Without PAD
INTRODUCTION: Exercise with an arm ergometer (EB) overcomes the main barrier to physical exercise in patients with Peripheral Artery Disease (PAD), leg pain during walking.
- Trial name
- NCT06828172
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Stroke, Sensorimotor Impairment Affecting the Upper Limb
Effectiveness of Active Exploration of Simulated Textures for Sensorimotor Recovery
Parallel-group, single-blinded controlled clinical trial. The study includes people aged 18-80 years, more than one month after stroke, with confirmed diagnosis, MoCA ≥ 20, and Barthel Index ≥ 3.
- Conditions
- Stroke, Sensorimotor Impairment Affecting the Upper Limb, Sensory Deficit, Rehabilitation
- Trial name
- NCT06962397
- Testing
- Active Touch-Based Sensory Training
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Pancreatic Cancer
Personalised Nutritional Care in Older Patients With Pancreatic Ductal Adenocarcinoma
NutriCa65-PDAC is a clinical study for patients aged 65 years or older with pancreatic ductal adenocarcinoma, a type of pancreatic cancer.
- Trial name
- NutriCa65-PDAC (NCT07821554)
- Testing
- Experimental: Personalised nutritional care delivered by a trained dietitian
- Where
- 5 sites in Denmark, Italy and 3 more
- Volunteers
- 250 people
- Sponsor
- Inna Chen, MD
Stroke, Stroke Rehabilitation
Evaluating Functional Outcomes of 3D-Printed Splints in Post-Stroke Upper Limb Recovery
This study aims to evaluate the upper limb motor recovery using a 3D-printed dynamic orthosis compared to a conventional one as part of a rehabilitation program in individuals with chronic stroke.
- Conditions
- Stroke, Stroke Rehabilitation, Hemiparesis of the Upper Limb Following Stroke
- Trial name
- 3D-splint (NCT07243314)
- Testing
- 3D Printed splint, conventional splint
- Where
- Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- King Saud University
SCI - Spinal Cord Injury, Upper Extremity Dysfunction
The Utilization Effects of Powered Wearable Orthotics in Improving Upper Extremity Function and ADL in Persons With SCI
To evaluate the usefulness of an upper extremity assistive device, called (MyoPro) in improving upper extremity activities in people with incomplete spinal cord injury. The Department of Defense is supporting this study.
- Conditions
- SCI - Spinal Cord Injury, Upper Extremity Dysfunction, Upper Extremity Problem
- Trial name
- NCT06349434
- Testing
- MyoMo, conventional therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kessler Foundation