Clinical trials: Upper Limb Functions
Acellular Dermal Matrix, Bone Grafting
Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix
This investigator-initiated study will compare ADM and resorbable cross-linked collagen membrane barriers for guided bone regeneration at atrophic lateral ridge augmentation sites.
- Conditions
- Acellular Dermal Matrix, Bone Grafting, Soft Tissue Grafting
- Trial name
- NCT07613047
- Testing
- Guided Bone Regeneration with ADM (AlloDerm) as a barrier, Guided Bone Regeneration with Resorbable Crosslinked Collagen Matrix (Mem-Lok) as a barrier
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Neurologic Diseases, Hemiparesis
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one…
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies
- Trial name
- NCT04798378
- Testing
- Neurosleeve
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Healthy
Evaluation of the Impact of Laterality on Brain Activation During a Virtual Mirror Therapy Task in Healthy Subjects
The aim of this study is to investigate the differences in brain activation in healthy subjects during virtual mirror therapy tasks, depending on the laterality of the task.
- Trial name
- LARTHEMIRS (NCT05793762)
- Testing
- Left virtual mirror therapy task, Right virtual mirror therapy task
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Athlete Assessment, Archery
Validity and Test-Retest Reliability of Reactive Neurocognitive Upper Extremity Tests in Archers
In archery, the evaluation of reaction time and neurocognitive functions plays a critical role in the management of upper extremity (UE) injuries and return-to-play (RTP) processes.
- Conditions
- Athlete Assessment, Archery, Neurocognitive Functional Performance Tests
- Trial name
- NCT07103824
- Testing
- Upper Extremity Neurocognitive Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Lateral Epicondylitis, Extracorporeal Shock Wave Therapy
Effect of Extracorporeal Shock Wave Therapy (ESWT) and Phonophoresis Treatment in Patients With Lateral Epicondylitis
This study aimed to investigate the effects of Extracorporeal Shock Wave Therapy and phonophoresis treatment on pain, function, hand grip strength and tendon thickness in ultrasonography in patients with lateral epicondylitis.
- Conditions
- Lateral Epicondylitis, Extracorporeal Shock Wave Therapy, Phonophoresis
- Trial name
- NCT06603181
- Testing
- conventional treatment, phonophoresis, extracorporeal shock wave therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Stroke, Hemiplegia
Use of Tendon Vibration and Mirror for the Improvement of Upper Limb Function and Pain Reduction
Upper limb paralysis following stroke is a very common problem. Only 30% of stroke patients who suffer from upper limb paresis experience a full recovery of function.
- Trial name
- VibMirror (NCT01010607)
- Testing
- Vibration and Mirror, Mirror therapy
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Cerebral Palsy
Task-oriented Game Therapy Using Enhances Functions in Children With Cerebral Palsy.
Cerebral Palsy is an umbrella definition that refers to a disorder that occurs after a problem affecting a person's brain functions and has symptoms such as sensory, motor and mental deficits.
- Trial name
- NCT06071182
- Testing
- Task-oriented Fruit ninja game
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Erzurum Technical University
Stroke
Non-Invasive Brain Signal Training to Induce Motor Control Recovery After Stroke
The purpose of this trial was to evaluate the benefits of combination motor learning training and brain computer interface training for restoring arm function in people with stroke.
- Trial name
- NCT00746525
- Testing
- Surface functional electrical stimulation (FES), Motor learning, Brain computer interface (BCI) training
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Louis Stokes VA Medical Center
Multiple Sclerosis
Investigation of Hand Functions and Related Parameters in People With Multiple Sclerosis
The upper extremity in people with Multiple Sclerosis (pwMS) has become a more popular research topic in recent years, with the increase in studies reporting widespread involvement.
- Trial name
- NCT04933110
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Uğur OVACIK
Chronic Obstructive Pulmonary Disease
The Differences of Muscle Activity Between Patients With COPD and Healthy Adults
The purpose of this study attempts to investigate the differences and relationships of respiratory parameters, muscle activity, and dyspnea during ADL between patients with COPD and age-matched healthy participants.
- Trial name
- NCT04146948
- Testing
- no intervention
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Neonatal Brachial Plexus Palsy
Forced Lefthandedness in Neonatal Brachial Plexus Palsy (NBPP) Children
The aim of the project is to assess the neurophysiological and functional consequences of forced lefthandedness in a population with right neonatal brachial plexus palsy (NBPP).
- Trial name
- NBPP (NCT04376372)
- Testing
- Functional testing, Magnetic resonance imaging, Electromyography
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Upper Extremity, Child
Functional Assessment Protocol for the Upper Limb for Pediatric Age
During data acquisition a trained therapist placed reflective markers on the skin of the participants in the selected body landmarks.
- Conditions
- Upper Extremity, Child, Range of Motion, Articular
- Trial name
- NCT06400667
- Testing
- Upper limb Kinematic Assessment with Optoelectronic system
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Functional Status, Muscle Tone
Effects of Cryotherapy on Upper Limb Balance Test
The shoulder joint is commonly used and also stricken by high loads and injuries in sports. One technique in emphasis is cryotherapy, a physiotherapeutical intervention characterized by the use of low temperatures for tissue…
- Trial name
- NCT05318664
- Testing
- Cryotherapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Flávia Carvalho
Parkinson Disease
Investigation of Validity and Reliability of the Minnesota Manual Dexterity Test in Parkinson's Disease
Parkinson's Disease (PD) is a disease that affects upper extremity functional skills with clinical findings such as bradykinesia, rigidity, and hypokinesia, and causes limitations in patients' daily life activities.
- Trial name
- NCT06713707
- Testing
- Manuel dexterity, Manual Dexterity (only MMDT)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Chronic Stroke, Non-use of the Paretic Upper Limb
Actimetry Monitoring of the Paretic Upper Limb in Chronic Post Stroke.
After a stroke, 80% of patients continue to have difficulty using their paretic upper limb in activities of daily living (ADL) despite post-stroke rehabilitation practices that aim to promote the use of the paretic upper limb.
- Trial name
- ParUse (NCT05581602)
- Testing
- Wearing bracelets (3-Axis Logging Accelerometer)
- Where
- 2 sites in France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Aging, Healthy
Study of Healthy Aging and Physical Function With Elamipretide
This study will utilize a daily dose of elamipetide for 4 weeks and will screen a sufficient number of subjects for 30 subjects to enroll in the study.
- Trial name
- SHAPE (NCT07275424)
- Testing
- Elamipretide will be supplied as a sterile 5.0 mL single-patient, multi-dose glass vial containing 3.75 mL of elamipretide solution (elamipretide [80 mg/mL], phosphate buffer, and benzyl alcohol)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- David Marcinek
Heart Rate Variability
Effects of Arm Crank Versus Treadmill Exercises on Heart Rate Variability in Adult Subjects.
Cardiovascular response to exercise affects the capacity of all body organs depending upon intensity, duration and mode of exercises.
- Trial name
- NCT03068182
- Testing
- Arm crank, Treadmill, Exercise
- Where
- Saudi Arabia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Cerebral Palsy, Somatosensory Disorders
The Effect Of Somatosensory Perceptıon And Proprıoceptıon On Upper Extremıty Functıonal Skılls
Cerebral Palsy (CP) is a non-progressive neurodevelopmental disorder characterized by posture and movement disorders as a result of damage to the immature brain for any reason before, during or after birth.In addition to tone…
- Conditions
- Cerebral Palsy, Somatosensory Disorders, Upper Extremity Dysfunction, Proprioceptive Disorders
- Trial name
- CP (NCT05213715)
- Testing
- assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Cerebrovascular Accident
Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis
The results of this study will provide sound, scientific evidence of physiologic mechanisms responsible for upper-extremity weakness; evidence of the processes involved in neuromuscular adaptation; and will elucidate the…
- Trial name
- NCT00125658
- Testing
- Control, Experimental
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development