Clinical trials: Upper Limb Motor Dysfunction
Stroke, Spasticity, Muscle
REHABOTICS: Integrated Rehabilitation System for People With Motor Disabilities
The goal of the Rehabotics project is the development of a comprehensive rehabilitation system to provide highly individualized treatment of upper limb function in patients with motor disorders due to acquired brain damage (eg…
- Conditions
- Stroke, Spasticity, Muscle, Upper Extremity Dysfunction
- Trial name
- NCT06519630
- Testing
- Rehabotics Physiotherapy, Traditional Physiotherapy
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Pantelis Syringas
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Acute Stroke, Upper Limb Motor Deficit
Effect of Early Tendon Vibrations on Upper Limb Motor Recovery After a Stroke
Strokes often induce a motor deficit. The resulting immobilization is in itself an aggravation factor since it worsens the motor deficit induced by the stroke itself.
- Trial name
- VIBRASTROKE (NCT07905625)
- Testing
- TVS rehabilitation sessions
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Stroke
Physical Performance and Cognitive Functions in Patients With Chronic Stroke
This study aims to investigate the impact of cognitive impairment on upper extremity physical performance, cognitive skills, and functional independence in individuals with chronic stroke.
- Trial name
- NCT07887776
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Kutahya Health Sciences University
Stroke, Upper Extremity Dysfunction
Dual Channel Rehabilitation Technology Promotes Rapid Recovery of Upper Limbs After Stroke
The injury and remodeling mechanism about upper extremity motor network after stroke is not clear. There are few studies on the motor network covering cortex, white matter and blood perfusion at the time.
- Conditions
- Stroke, Upper Extremity Dysfunction, Transcranial Direct Current Stimulation, Image, Body
- Trial name
- NCT04944680
- Testing
- Transcranial Direct Current Stimulation therapy, Motor imagery therapy, Transcranial Direct Current Stimulation and motor imagery therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Cerebral Palsy
Non Invasive Vagus Nerve Stimulation in Cerebral Palsy (BOOSTTVNS)
The present study aims to assess, through a randomized controlled trial (RCT), the efficacy of transcutaneous Vagus Nerve Stimulation (tVNS) in enhancing the functional changes due to an intensive motor training in children and…
- Trial name
- (BOOSTTVNS) (NCT06372028)
- Testing
- transcutaneous vagus nerve stimulation (tVNS)
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- IRCCS Eugenio Medea
Feasibility Study, Post-Stroke Patients With Upper Extremity Motor Deficit
Contralesional Inhibitory rTMS for Recovery of Arm Function After Stroke
The CanStim consensus working group (multidisciplinary team of experts in rTMS from institutions across Canada) developed consensus recommendations for a protocol to deliver rTMS as an adjunct to a standard behavioral…
- Conditions
- Feasibility Study, Post-Stroke Patients With Upper Extremity Motor Deficit, Post-Stroke Patients With Cognitive Deficits
- Trial name
- ConTRAstroke (NCT04205526)
- Testing
- Active rTMS
- Where
- Canada
- Volunteers
- 83 people
- Sponsor
- Thiel, Alexander, M.D.
Stroke Rehabilitation
Multimodal Correction of Post-stroke Motor and Cognitive Impairments
The aim of the study is the development and scientific substantiation of the effectiveness and safety of multimodal rehabilitation technology using innovative digital technologies, biofeedback (BFB), virtual reality (VR)…
- Trial name
- NCT05391919
- Testing
- Multimodal technology (MT), Conventional rehabilitation (CR)
- Where
- Russia
- Volunteers
- 90 people
- Sponsor
- Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine
Stroke
Virtual Reality's Impact on Upper Limb Function in Post-stroke Patients
Stroke rank second among the top causes of death, affecting millions of people in the worldwide. Approximately 70-80% survivors of stroke could experience various levels of upper limb motor impairments, which seriously affects…
- Trial name
- NCT06881680
- Testing
- virtual reality (VR) head mounted display
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Qilu Hospital of Shandong University
Hemiplegic Cerebral Palsy, Mirror Hands
Mirror Therapy in Children With Hemiparetic Cerebral Palsy
Cerebral palsy (CP) is a neurodevelopmental disorder that frequently impairs upper extremity motor control and hand function, resulting in limitations in daily activities.
- Conditions
- Hemiplegic Cerebral Palsy, Mirror Hands, Upper Extremity Dysfunction, Motor Activity
- Trial name
- NCT07734376
- Testing
- Mirror Therapy, Conventional Physiotherapy
- Volunteers
- 26 people
- Sponsor
- Marmara University
Stroke, Spinal Cord Injuries
ZEPU-AI Series Limb Feedback Robot Training Study (ZEPUAISRCT)
The goal of this clinical trial is to learn whether robotic rehabilitation devices (ZEPU-AI2, AI4, AI6 Plus, and AI7A) are feasible, safe, and effective for adults with upper or lower limb motor problems.
- Conditions
- Stroke, Spinal Cord Injuries, Brain Injuries, Traumatic, Movement Disorder, Upper Extremity
- Trial name
- NCT07749625
- Testing
- ZEPU-AI2, ZEPU-AI4, ZEPU-AI6 Plus
- Where
- Bangladesh
- Volunteers
- 36 people
- Sponsor
- Bangladesh Medical University
Chronic Stroke
Exoskeleton Research: Myoelectric Orthosis for Rehab of Severe Chronic Arm Motor Deficits
This study will evaluate the effects of combining motor learning-based therapy with use of the MyoPro , a wearable exoskeletal myoelectrically controlled orthotic device.
- Trial name
- NCT05296408
- Testing
- motor learning based therapy, MyoPro, Home Exercise Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- VA Office of Research and Development
Stroke, Hemiparesis
"Comparison of Therapist-Led and Robot-Assisted Arm Therapy in Subacute Stroke Rehabilitation"
This study aims to compare the outcomes of upper limb motor therapy conducted by a physiotherapist with robot-assisted therapy using the Luna EMG device in patients in the subacute phase after stroke.
- Conditions
- Stroke, Hemiparesis, Muscle Spasticity, Upper Extremity Dysfunction
- Trial name
- NCT07002463
- Testing
- Luna EMG, Therapist-assisted upper limb training
- Where
- Poland
- Volunteers
- 58 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Spina Bifida, Sensory Disorder
Sensory and Motor Proficiency For Children With Spina Bifida
Spina bifida is one of the neural tube defects that cause neuromuscular dysfunction. Spina bifida is a disease accompanied by motor paralysis, musculoskeletal problems, Arnold-Chiari malformation, osteoporosis, hydrocephalus…
- Conditions
- Spina Bifida, Sensory Disorder, Motor Disorders, Upper Extremity Dysfunction
- Trial name
- NCT05318677
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Stroke, Upper Extremity Dysfunction
Effects of Combined vs. Sequential Attentional Focus Instructions on Upper Extremity Function in Subacute Stroke
Stroke is a leading cause of long-term disability, and upper extremity impairments-affecting about 80% of survivors-limit functional reach, grasp, and manipulation more severely than lower limb deficits.
- Conditions
- Stroke, Upper Extremity Dysfunction, Cue, Threat
- Trial name
- NCT07289308
- Testing
- Combined Focus of Attention Instructions, Sequential Focus of Attention Instructions, standart rehabilitation program
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Bahçeşehir University
Stroke
Treatment of Hand Dysfunction After Stroke
Many stroke survivors exhibit persistent upper limb motor deficits and a non-functional upper limb. There is some promising information that suggests motor learning (ML) in conjunction with functional electrical stimulation (FES…
- Trial name
- NCT00508521
- Testing
- Functional Electrical Stimulation, Standard Care
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- US Department of Veterans Affairs
Stroke, Stroke with Hemiparesis
Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using Functional Near Infrared Spectroscopy (fNIRS)
The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy…
- Conditions
- Stroke, Stroke with Hemiparesis, Stroke, Ischemic
- Trial name
- NCT06806397
- Testing
- Stimulus response task
- Where
- 2 sites in Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Stroke, Parkinson Disease
PhiCube for Bilateral Upper Limb Neuromotor and Cognitive Rehabilitation in Adults
This randomized controlled pilot trial evaluates the usability and safety of PhiCube, a compact, portable, bilateral end-effector robotic device for upper limb rehabilitation, and its impact on motor and cognitive function.
- Conditions
- Stroke, Parkinson Disease, Amyotrophic Lateral Sclerosis, Spinal Cord Injuries
- Trial name
- PhiCube-Adults (NCT07865260)
- Testing
- PhiCube, Conventional rehabilitation
- Where
- 4 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato
Parkinson's Disease, Somatosensory Disorders
Somatosensory Dysfunction as the Underlying Mechanism of Upper Limbs Motor Blocks in People With Parkinson's Disease
Motor blocks during gait and upper limb movements (FOULs) are a disabling and common motor impairment in mild to severe stages of Parkinson's disease (PD).
- Trial name
- NCT02610257
- Testing
- Mechanical stimulus (vibration) applied on the forearm
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Breast Cancer, Upper Extremity Dysfunction
Exercise Rehabilitation Via a Mobile Application for Individuals With Breast Cancer Undergoing Chemotherapy
The primary purpose of this study is to determine the feasibility of our proposed intervention approach involving (1) an integrated physiotherapy and exercise intervention for individuals with breast cancer who are undergoing…
- Trial name
- Empower (NCT05254678)
- Testing
- general exercise
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Alberta