Clinical trials: Upper Limb Motor Dysfunction
Stroke, Rehabilitation; Tobacco Use
Quantitative Prognostic Analysis of Upper Limb Motor Dysfunction After Stroke
30% - 66% of stroke survivors have upper limb dysfunction. Effective rehabilitation can improve the prognosis, but the rehabilitation resources are limited.
- Conditions
- Stroke, Rehabilitation; Tobacco Use, Upper Extremity Dysfunction, Prognosis
- Trial name
- NCT05410054
- Testing
- no intervention
- Volunteers
- 178 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Cognitive Impairment
The Effect of Upper Limb Low-intensity Motor Control Training Program on Cognitive Function in Healthy Older Adults
This healthy volunteer intervention study is designed to evaluate the effectiveness of upper limb motor control training (uMCT) on physical and cognitive functions in older adults.
- Trial name
- uMCON (NCT06962722)
- Testing
- Upper limb motor control training (uMCON)
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Stroke, Upper Extremity Dysfunction
I2-CoRT WTP9: Upper Extremity Motor Intervention, Use of Hand Orthosis in People Post-stroke
The upper extremity kinematics of people post-stroke will be monitored with/without an inactive hand orthosis (intervention: added weight to hand) during ARAT, Fugl-Meyer, and Box and Blocks tests.
- Trial name
- NCT04265079
- Testing
- Additional weight at hand
- Sponsor
- Maastricht University
Upper Limb Motor Dysfunction, Stroke
ZEPU-SGI1PLUS Hand Training Study (ZEPUSGI1RCT)
The goal of this pilot randomized controlled trial is to learn whether the ZEPU-SG1PLUS Hand Functional Comprehensive Training System - a robotic device used alongside standard rehabilitation - is safe, feasible, and helpful for…
- Conditions
- Upper Limb Motor Dysfunction, Stroke, Incomplete Spinal Cord Injury, Traumatic Brain Injury
- Trial name
- NCT07739264
- Testing
- ZEPU-SG1PLUS Hand Functional Comprehensive Training System, Standard-of-Care Rehabilitation
- Where
- Bangladesh
- Volunteers
- 36 people
- Sponsor
- Bangladesh Medical University
Stroke, Upper Limb Motor Deficit
Prediction of Post-stroke Motor Recovery
The prediction of motor recovery in the acute phase of stroke is crucial for several clinical reasons: (i) informing the patient and his relatives, (ii) helping to identify the patient's endorsement (return home or…
- Trial name
- PREP-AVC (NCT04574037)
- Testing
- Clinical scores such as SAFE score, NIHSS; demographic data such as age and electrophysiological data (such as the absence/presence of Motor evoked potential)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Pain, Low Back Pain
Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain
The purpose of this study is to investigate, in two phases: (1) the feasibility and safety of Virtual Embodiment Therapy in treating chronic pain of lower back and upper limbs and (2) the efficacy of Virtual Embodiment Therapy on…
- Conditions
- Chronic Pain, Low Back Pain, Fibromyalgia, Upper Extremity Dysfunction
- Trial name
- NCT04060875
- Testing
- Karuna Labs Virtual Reality Software
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Karuna Labs Inc.
Stroke, Incomplete Spinal Cord Injury (SCI)
ZEPU-2000 Limb Rehabilitation Trainer Study (ZEPU2000RCT)
The goal of this clinical trial is to learn whether the ZEPU-2000A, ZEPU-2000D and ZEPU-2000E robotic rehabilitation trainers help people with weakness or movement problems in their arms and legs.
- Conditions
- Stroke, Incomplete Spinal Cord Injury (SCI), Traumatic Brain Injury, Upper Extremity Motor Dysfunction
- Trial name
- NCT07749612
- Testing
- ZEPU-2000A, ZEPU-2000D, ZEPU-2000E
- Where
- Bangladesh
- Volunteers
- 36 people
- Sponsor
- Bangladesh Medical University
Stroke, Multiple Sclerosis
Upper Limb Muscle Strength Models for Patients With Motor Impairment.
Upper limb motor impairments are common. They affect quality of life and can lead to dependency. They are mainly due to neurological conditions such as stroke, multiple sclerosis, and traumatic spinal cord injury.
- Conditions
- Stroke, Multiple Sclerosis, Spinal Cord Injuries
- Trial name
- MusMapS (NCT06608121)
- Testing
- Upper limb isokinetic forces measurements
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Pôle Saint Hélier
Stroke, Amyotrophic Lateral Sclerosis
Auto-calibrating System for Upper Limb Disability Assessment, Neurological and Occupational Rehabilitation
This interventional, multicenter, low-intervention clinical trial aims to evaluate the usability, feasibility, safety, and preliminary clinical impact of a robotic rehabilitation system designed for upper limb rehabilitation in…
- Conditions
- Stroke, Amyotrophic Lateral Sclerosis, PARKINSON DISEASE (Disorder), Mild Cognitive Impairment (MCI)
- Trial name
- ASULDAR (NCT07636538)
- Testing
- Auto-calibrating System for Upper Limb disability Assessment, neurological and occupational Rehabilitation, conventional therapy
- Volunteers
- 30 people
- Sponsor
- University of Pavia
Stroke, Neurologic Deficits
Optimal Therapeutic Dose of tDCS for Functional Upper Limb Recovery in People With Stroke
Stroke is one of the main causes of disability worldwide. The main disability after a stroke is hemiparesis of an Upper Limb (UL), with a prevalence of 70%.
- Trial name
- NCT06396715
- Testing
- Transcranial direct current stimulation
- Volunteers
- 36 people
- Sponsor
- University of Chile
Breast Cancer, Exercise
Virtual Reality-based Exercise Training in Radiotherapy Period After Breast Cancer Surgery
The main purpose of this study is to compare two different exercise approaches during the radiotherapy period in patients who have undergone breast cancer surgery.
- Conditions
- Breast Cancer, Exercise, Upper Extremity Dysfunction
- Trial name
- NCT04618120
- Testing
- Virtual reality-based exercise, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Gazi University
Stroke, Paresis
Music Therapy to Restore Motor Deficits After Stroke
Motor deficits are common after stroke, being one of the major causes of disability in this population. Because of the impact that motor impairments have in the life of patients and the associated financial costs, it is a health…
- Trial name
- NEUROMUSIC (NCT02208219)
- Testing
- Music-supported Therapy, home-based Music-supported Therapy, Conventional treatment
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Barcelona
Upper Extremity, Acupuncture Therapy
Scalp Acupuncture Combined With rTMS for Upper Limb Motor Dysfunction in Stroke: A Brain Network Study
This study aims to compare the improvement effects of the rTMS (repetitive transcranial magnetic stimulation) combined with conventional rehabilitation therapy group with the rTMS combined with scalp acupuncture and conventional…
- Conditions
- Upper Extremity, Acupuncture Therapy, Stroke, Transcranial Magnetic Stimulation Repetitive
- Trial name
- NCT07210944
- Testing
- Repetitive transcranial magnetic stimulation, Scalp acupuncture, Conventional rehabilitation treatment
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Debiao Kong
Stroke, Upper Extremity Dysfunction
Exoskeleton-assisted Upper Limb Rehabilitation After Stroke
In recent studies, it has been observed that robotic devices make a positive contribution to motor recovery and the activities of daily living.
- Trial name
- NCT04353622
- Testing
- Exoskeleton robot for upper extremity, Conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Marmara University
Adrenomyeloneuropathy Without Cerebral Involvement
Epidural Spinal Cord Stimulation for Lower-limb Impairment in Adrenomyeloneuropathy
Adrenal spinal neuropathy (AMN) is a rare X-linked genetic disease caused by mutations in the ABCD1 gene, and belongs to a special type of adrenal leukodystrophy.
- Trial name
- EPIC-AMN (NCT06796920)
- Testing
- Spinal cord stimulation
- Where
- 4 sites in China
- Volunteers
- 10 people
- Sponsor
- Third Military Medical University
Stroke, Upper Extremity Paresis
rTMS Combined With Motor Training for the Treatment of Upper Limb Motor Dysfunction in Stroke Patients
The goal of this clinical trials is to investigate the effectiveness of online repetitive transcranial magnetic stimulation (rTMS) in enhancing upper limb motor rehabilitation during the subacute and chronic phase of stroke.
- Trial name
- NCT06752499
- Testing
- Online stimulation, Offline stimulation
- Where
- 3 sites in China
- Volunteers
- 60 people
- Sponsor
- Ruijin Hospital
Cerebrovascular Accident
Ischemic Nerve Block to Improve Hand Function in Stroke Patients
This study will determine whether impaired hand function due to stroke can be improved by blocking nerve impulses to the unaffected arm.
- Trial name
- NCT00056706
- Testing
- Transient deafferentation
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Palsy
Transcranial Alternating Current Stimulation in Cerebral Palsy (BOOSTTACS)
The present study aims to assess, through a randomized controlled trial (RCT), the efficacy of transcranial alternating current stimulation (tACS) in enhancing the functional changes due to an intensive motor training in children…
- Trial name
- BOOSTTACS (NCT06372041)
- Testing
- transcranial Alternating Current Stimulation
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- IRCCS Eugenio Medea
Stroke, Upper Extremity Motor Function
Invasive Vagus Nerve Stimulation Paired With Rehabilitation After Stroke
This study evaluated the feasibility, safety, and preliminary functional outcomes of invasive vagus nerve stimulation (iVNS) paired with upper-limb rehabilitation in participants with chronic stroke-related upper-limb motor…
- Conditions
- Stroke, Upper Extremity Motor Function, Intracerebral Hemorrhage
- Trial name
- VNS-Stroke (NCT07736573)
- Testing
- Invasive Vagus Nerve Stimulation
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Beijing Chao Yang Hospital
Upper Extremity Dysfunction, Traumatic Brain Injury
Targeted Noninvasive Brain Stimulation (T-NIBS) to Improve Hand Motor Functions in Acquired Brain Injury
Acquired Brain Injury (TBI) is a serious medical and health problem in the US. Individuals with an acquired brain injury due to stroke and Traumatic Brain Injury (TBI) commonly suffer from upper extremity physical impairments…
- Trial name
- NCT04057105
- Testing
- Active High-definition Transcranial Direct Current Stimulation (HD-tDCS), MusicGlove
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Kessler Foundation