Clinical trials: Upper Limb Paresis
Stroke, Activities, Motor
INTENSIVE TREATMENT WITH ROBOTIC PLUS VIBRATION IN STROKE
The Amadeo® Manual Robotic System (Tyromotion GmbH, Graz, Austria) is designed for rehabilitative treatment of the hand and fingers providing robot-assisted exercise for the finger flexors and extensors.
- Conditions
- Stroke, Activities, Motor, Quality of Life, Sensitivity
- Trial name
- VIBRAROBOT (NCT04762940)
- Testing
- Robotic, Vibration
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Rey Juan Carlos
Infant Development, Hemiplegia
CIMT and taVNS for Hemiplegia in Infants
Newborns who are born premature or suffer brain injury at birth are at risk for motor problems that may cause weakness in reaching and grasping on one side of the body.
- Conditions
- Infant Development, Hemiplegia, Constraint Induced Movement Therapy
- Trial name
- NCT05101707
- Testing
- transcutaneous auricular vagus nerve stimulation, Constraint induced movement therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Medical University of South Carolina
Ischemic Stroke, Upper Extremity Paresis
Motor Task Performance Under Visual and Auditory Feedback Post Stroke: a Randomized Crossover Trial
The study was designed to evaluate the impact of a novel kinematic biofeedback system - SWORD - in the motor performance of patients after stroke.
- Trial name
- NCT03032692
- Testing
- SWORD, Exercise with biofeedback, exercise without biofeedback
- Where
- 3 sites in Portugal
- Volunteers
- 30 people
- Sponsor
- Sword Health, SA
Stroke
Mirror Therapy: Effects on Functional Recuperation of Severe Upper Limb Paresis After Stroke
After stroke, patients frequently suffer from arm or hand weakness. There are numerous rehabilitation methods to stimulate recovery, amongst which mirror therapy (MT).
- Trial name
- MT (NCT02949609)
- Testing
- Mirror Therapy, Control Therapy
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- University Hospital, Geneva
Hemiplegia and Hemiparesis, Acquired Brain Injury
Effectiveness of the Neural Mobilization on Upper Limb Functionality in Patients With Acquired Brain Injury
The main objective: To determine changes in physiological and structural properties of upper limb muscles with spasticity in patients with acquired brain injury after applying neural mobilization improving their functional…
- Trial name
- NCT04652934
- Testing
- Neurodynamic, Mimic group
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Vanesa Abuín
Stroke, Chronic Stroke
Personalized Transcranial Direct Current Stimulation in Stroke Recovery
The central objective of this application is to explore the neural substrate of personalized tDCS (ptDCS) and to determine whether the paradigm for each stroke patient can predict the amount of sustained clinical improvement…
- Conditions
- Stroke, Chronic Stroke, Hemorrhage Brain, Ischemic Stroke
- Trial name
- NCT06286800
- Testing
- Transcranial direct current stimulation (tDCS) with OT
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The Methodist Hospital Research Institute
Cerebral Palsy, Upper Extremity Paresis
Virtual Reality Mediated Upper Extremity rehabilitationPatients With Cerebral Palsy
Cerebral palsy (CP) refers to a group of permanent disorders that occur in the brain of the fetus or infant, which are non-progressive, cause movement and posture disorder along with activity limitation.
- Trial name
- NCT04529343
- Testing
- Virtual reality mediated upper extremity rehabilitation, Classical exercise therapy for upper extremities
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Stroke, Hemiparesis
Feasibility of Action Observation and Repetitive Task Practice on Upper Extremity Outcomes in Chronic Stroke Survivors
The objective of this pilot randomized controlled single blinded, parallel-group study is to detect change of the Action Observation (AO) and Repetitive Task Practice (RTP) combined practice schedule on upper limb motor…
- Trial name
- NCT04015271
- Testing
- Action Observation + Repetitive Task Practice
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ohio State University
Stroke, Brain Infarction
Critical Periods After Stroke Study (CPASS)
To perform an exploratory single center randomized study that will form the basis for a larger scale, more definitive randomized clinical trial to determine the optimal time after stroke for intensive motor training.
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- CPASS (NCT02235974)
- Testing
- Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MedStar National Rehabilitation Network
Stroke, Acute, Stroke
Functional Electrical Stimulation (FES) for Upper Extremity Recovery in Stroke
Stroke is the leading cause of activity limitation among older adults in the United States. NeuroMuscular Electrical Stimulation (NMES) can assist stroke survivors in regaining motor ability and decreasing activity limitation…
- Conditions
- Stroke, Acute, Stroke, Hemiparesis
- Trial name
- NCT00142792
- Testing
- NMES device with EMG-triggered and Cyclic capabilities
- Where
- 3 sites in United States
- Volunteers
- 122 people
- Sponsor
- MetroHealth Medical Center
Stroke (CVA) or TIA, Hemiparesis
Mirror Therapy on Motor Recovery and Pain of Hemiparetic Arm
evaluate the effect of mirror therapy on motor recovery and pain of hemiparetic arm post stroke
- Trial name
- NCT07358169
- Testing
- technique, Control
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
CVA (Cerebrovascular Accident), Stroke
Constraint-Induced Movement Therapy Plus Sensory Components After Stroke
Constraint-Induced Movement Therapy or CI Therapy is a form of treatment that systematically employs the application of selected behavioral techniques delivered in intensive treatment over consecutive day with the following…
- Conditions
- CVA (Cerebrovascular Accident), Stroke, Upper Extremity Paresis
- Trial name
- NCT05515237
- Testing
- Grade 2-5 CI Therapy + Sensory Components
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Alabama at Birmingham
Stroke
Passive Robots for Stroke Rehabilitation: A Feasibility Study
The purpose of this study is to examine the feasibility and effectiveness of a novel, multimodal approach that combines passive devices with noninvasive neuromuscular stimulation for upper extremity rehabilitation after stroke.
- Trial name
- NCT07218276
- Testing
- Functional Training with SepaRRo and NeuRRoFES
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Michigan
Stroke, Brain Injuries
Safety and Efficacy Evaluation of the Robotic Enhanced Error Training of Upper Limb Function in Post-stroke and Post TBI Participants
Background: Cerebrovascular accident [CVA or commonly known as stroke] and traumatic brain injury (TBI) are common causes of morbidity, and motor impairments.
- Conditions
- Stroke, Brain Injuries, Paresis, Cerebrovascular Disorders
- Trial name
- NCT06010823
- Testing
- PlaXtreme
- Where
- 2 sites in Israel
- Volunteers
- 96 people
- Sponsor
- Reuth Rehabilitation Hospital
Moderate Arm Paresis, Ischemic Stroke
Comparison of Four-Channel Functional Electrical Stimulation vs. One-Channel Electrical Stimulation on Moderate Arm/Hand Paresis in Subacute Stroke Patients
This study will compare two treatments that may help participants recover after having suffered from stroke. Persons who experience weakness or paralysis of their arms/hands will be randomly placed in one of two groups.
- Trial name
- MKES2 (NCT07098572)
- Testing
- Cyclic single channel neuromuscular stimulation, Electromyogram-triggered 4 channel neuromuscular stimulation
- Where
- 3 sites in Austria
- Volunteers
- 44 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Hemiparesis, Stroke
Visual Feedback Therapy for Treating Individuals With Hemiparesis Following Stroke
The purpose of the study is to determine whether an existing treatment for problems that participants have with making movements after a stroke can be performed at home.
- Trial name
- NCT01662960
- Testing
- Mirror therapy, Divider therapy
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Albert Einstein Healthcare Network
Hemiparesis, Cerebral Palsy
A Modified Constraint-Induced Movement Therapy Program in Rehabilitation of Arm Paresis in Children With Cerebral Palsy
The purpose of this study is to determine if a modified protocol of constraint-induced movement therapy (CIT) is effective in rehabilitation treatment of arm paresis in children with cerebral palsy.
- Trial name
- mCIT (NCT00473447)
- Testing
- Modified Constraint-induced movement therapy
- Volunteers
- 10 people
- Sponsor
- Universita di Verona
Muscle Weakness
Benefits of Upper Extremity Exercises
Pt will be provided with a upper extremity exercise program that will be completed daily during their session with occupational therapy.
- Trial name
- NCT02888015
- Testing
- upper extremity exercise program
- Volunteers
- 6 people
- Sponsor
- State University of New York - Upstate Medical University
Spontaneous Intracerebral Hemorrhage, Motor Function
Rehabilitation Paired with VNS for Motor Function Recovery
The goal of this clinical trial is to investigate the efficacy and safety of vagus nerve stimulation (VNS) combined with rehabilitation in improving upper extremity motor function after spontaneous intracerebral hemorrhage (ICH).
- Conditions
- Spontaneous Intracerebral Hemorrhage, Motor Function, Upper Extremity Injury, Rehabilitation
- Trial name
- NCT06892574
- Testing
- Active-VNS
- Volunteers
- 10 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Ischemic Stroke, Chronic Stroke
Investigation of Neural Stem Cells in Ischemic Stroke
A study of stereotactic, intracerebral injection of CTX0E03 neural stem cells into patients with moderate to moderately severe disability as a result of an ischemic stroke.
- Conditions
- Ischemic Stroke, Chronic Stroke, Hemiparesis, Arm Paralysis
- Trial name
- PISCES III (NCT03629275)
- Testing
- CTX0E03 Drug Product and delivery device
- Where
- 23 sites in United States
- Volunteers
- 15 people
- Sponsor
- ReNeuron Limited