Hemiplegia and HemiparesisNCT04652934
Effectiveness of the Neural Mobilization on Upper Limb Functionality in Patients With Acquired Brain Injury
A study testing Neurodynamic and Mimic group in people with Hemiplegia and Hemiparesis and Acquired Brain Injury, run by Vanesa Abuín at 1 site in Spain.
Trial summary
The main objective: To determine changes in physiological and structural properties of upper limb muscles with spasticity in patients with acquired brain injury after applying neural mobilization improving their functional performance, their participation in society and quality of life. Read more about this study
- Who is it for?
- Ages 25 to 50 years
- Conditions the study is for
- Hemiplegia and Hemiparesis, Acquired Brain Injury
- What is being tested?
- Neurodynamic and Mimic group
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 24 participants
- Where
- 1 siteSpain
- Study dates
- 26 Jan 2022to 28 Jul 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Diagnosis of acquired brain injury (hemiplegia-hemiparesis)
- Ages between 25 and 50 years
Who cannot join
- Unable to understand and respond to verbal instructions
- Absence of voluntary movement in the upper limb
- Take medicine for spasticity
- Botulinum toxin infiltration in the last 6 months
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effectiveness of the Neural Mobilization on Upper Limb Functionality in Patients With Acquired Brain Injury: Randomized, Controlled, Multi-Centric, Single-Blind Clinical Trial
The main objective:
To determine changes in physiological and structural properties of upper limb muscles with spasticity in patients with acquired brain injury after applying neural mobilization improving their functional performance, their participation in society and quality of life.
Hypothesis:
Peripheral nerve mobilizations performed with neurodynamic techniques in upper limb in patients with acquired brain injury, generate changes at structural and physiological level, favoring the performance of daily life activities and improving the quality of life.
Read the detailed description
Randomized clinical trial with blinding of the subject, the evaluator and the person analyzing the data.
In the experimental group will be performed neural mobilitazion technique, while in the sham a technique to mimic neurodynamic.
The assessment will be made by a single evaluator.
- Conditions
- Hemiplegia and Hemiparesis, Acquired Brain Injury
- Being tested
- Neurodynamic, Mimic group
- Keywords
- Acquired Brain Injury, Hemiplegia, Neural Mobilization, Upper limb
- Medical subject headings
- Hemiplegia, Paresis, Brain Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
NeurodynamicOther
The Upper Limb Neurodynamic Test (ULNT1) technique described by Butler will be performed on the affected limb. This technique consists of performing shoulder depression, 90º shoulder abduction, hand, wrist and forearm in a neutral position, external rotation of the shoulder and extension of the elbow. After positioning the limb in this position, wrist flexion-extension movements will be performed smoothly and rhythmically of 20 movements every minute, for 3 minutes, three times per session with 1 minute of rest between each series.
Mimic groupOther
The protocol used by Beneciuk et al. Will be used. This intervention consists of imitating NM without stressing the nervous system. It will be carried out as follow: a neutral cervical position will be maintained (0º of cervical inclination), 45º of shoulder abduction without depression, 45º of external rotation of the shoulder combined with 45º of elbow flexion with the forearm in pronation. Afterwards, 10 wrist flexion-extension movements will be performed at a rate of 6 seconds per cycle (3 seconds of flexion and 3 seconds of extension). The resistance that you will feel will stabilize when you change motion. Once the 10 cycles of movements have been carried out, a wrist flexion will be maintained for 10 seconds.
| Study group | Role | What they receive |
|---|---|---|
| Intervention group | Experimental | The Upper Limb Neurodynamic Test (ULNT1) technique described by Butler will be performed on the affected limb. This technique consists of performing shoulder depression, 90º shoulder abduction, hand, wrist and forearm in a neutral position, external rotation of the shoulder and extension of the elbow. After positioning the limb in this position, wrist flexion-extension movements will be performed smoothly and rhythmically of 20 movements every minute, for 3 minutes, three times per session with 1 minute of rest between each series. Receives: Other: Neurodynamic |
| Mimic group | Sham comparator | The protocol used by Beneciuk et al. Will be used. This intervention consists of imitating NM without stressing the nervous system. It will be carried out as follow: a neutral cervical position will be maintained (0º of cervical inclination), 45º of shoulder abduction without depression, 45º of external rotation of the shoulder combined with 45º of elbow flexion with the forearm in pronation. Afterwards, 10 wrist flexion-extension movements will be performed at a rate of 6 seconds per cycle (3 seconds of flexion and 3 seconds of extension). The resistance that you will feel will stabilize when you change motion. Once the 10 cycles of movements have been carried out, a wrist flexion will be maintained for 10 seconds. Receives: Other: Mimic group |
What is being measured
The primary outcome is the main question the study is designed to answer.
Changes in Manual Ability
Abilhand Scale; Score 0(worse outcome)-2(better outcome)
Measured: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Changes in Muscle Spasticity
MAS (Modified Ashworth Scale) 0 (better outcome) - 4 (worse outcome)
Measured: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Changes in Muscle Strength
Dynamometer
Measured: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Changes in Nervous Conduction
Delsys Trigno Avanti (surface eMG for non-invasive assessment of muscles)
Measured: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Changes in Upper Limb Pain Perception
EVA (Visual Analog Scale) 0 (worse outcome) - 10 (better outcome)
Measured: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Changes in Upper Limb Pain to Pressure
Algometer
Measured: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Dec 2020
- Study start26 Jan 2022
- Primary completion28 Jul 2023
- Study completion28 Jul 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (45)Papers the sponsor has linked to this study.
- Other trials for Hemiplegia and HemiparesisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Randomized Controlled Trial
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 24 participants (actual)
Sponsor and investigators
- Lead sponsor
- Vanesa Abuín
- Sponsor type
- University, hospital or other
- Collaborators
- Universidad Europea de Madrid
- Responsible party
- Sponsor-investigator, Vanesa Abuín, Universidad Europea de Madrid
- Investigators
- Vanesa Abuín, Dr, Study chair, Universidad Europea de MadridLeticia Martínez, Dr, Study director, Universidad Europea de MadridAlmudena Buesa, Dr, Study chair, Universidad San Jorge de Zaragoza
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04652934
- Sponsor's protocol ID
- HUFA CEIC 20/154
- Status last verified
- Jul 2023
- First submitted
- 8 Oct 2020
- Last updated
- 1 Aug 2023
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
The World Health report 1996--fighting disease, fostering development. World Health Forum. 1997;18(1):1-8.
PubMed 9233055Synnot A, Chau M, Pitt V, O'Connor D, Gruen RL, Wasiak J, Clavisi O, Pattuwage L, Phillips K. Interventions for managing skeletal muscle spasticity following traumatic brain injury. Cochrane Database Syst Rev. 2017 Nov 22;11(11):CD008929. doi: 10.1002/14651858.CD008929.pub2.
PubMed 29165784Basson A, Olivier B, Ellis R, Coppieters M, Stewart A, Mudzi W. The Effectiveness of Neural Mobilization for Neuromusculoskeletal Conditions: A Systematic Review and Meta-analysis. J Orthop Sports Phys Ther. 2017 Sep;47(9):593-615. doi: 10.2519/jospt.2017.7117. Epub 2017 Jul 13.
PubMed 28704626Martins C, Pereira R, Fernandes I, Martins J, Lopes T, Ramos L, Pacheco J, Silva AG. Neural gliding and neural tensioning differently impact flexibility, heat and pressure pain thresholds in asymptomatic subjects: A randomized, parallel and double-blind study. Phys Ther Sport. 2019 Mar;36:101-109. doi: 10.1016/j.ptsp.2019.01.008. Epub 2019 Jan 23.
PubMed 30710858Beltran-Alacreu H, Jimenez-Sanz L, Fernandez Carnero J, La Touche R. Comparison of Hypoalgesic Effects of Neural Stretching vs Neural Gliding: A Randomized Controlled Trial. J Manipulative Physiol Ther. 2015 Nov-Dec;38(9):644-652. doi: 10.1016/j.jmpt.2015.09.002. Epub 2015 Oct 23.
PubMed 26481666Almeida RS, Machado E, Yamato TP, Santos De Melo L, Nogueira LAC. Pragmatic neural tissue management improves short-term pain and disability in patients with sciatica: a single-arm clinical trial. J Man Manip Ther. 2019 Sep;27(4):208-214. doi: 10.1080/10669817.2019.1580420. Epub 2019 Feb 26.
PubMed 30935325Ayub A, Osama M, Ahmad S. Effects of active versus passive upper extremity neural mobilization combined with mechanical traction and joint mobilization in females with cervical radiculopathy: A randomized controlled trial. J Back Musculoskelet Rehabil. 2019;32(5):725-730. doi: 10.3233/BMR-170887.
PubMed 30664500Kim DG, Chung SH, Jung HB. The effects of neural mobilization on cervical radiculopathy patients' pain, disability, ROM, and deep flexor endurance. J Back Musculoskelet Rehabil. 2017 Sep 22;30(5):951-959. doi: 10.3233/BMR-140191.
PubMed 28453446Ferragut-Garcias A, Plaza-Manzano G, Rodriguez-Blanco C, Velasco-Roldan O, Pecos-Martin D, Oliva-Pascual-Vaca J, Llabres-Bennasar B, Oliva-Pascual-Vaca A. Effectiveness of a Treatment Involving Soft Tissue Techniques and/or Neural Mobilization Techniques in the Management of Tension-Type Headache: A Randomized Controlled Trial. Arch Phys Med Rehabil. 2017 Feb;98(2):211-219.e2. doi: 10.1016/j.apmr.2016.08.466. Epub 2016 Sep 10.
PubMed 27623523Sanz DR, Solano FU, Lopez DL, Corbalan IS, Morales CR, Lobo CC. Effectiveness of median nerve neural mobilization versus oral ibuprofen treatment in subjects who suffer from cervicobrachial pain: a randomized clinical trial. Arch Med Sci. 2018 Jun;14(4):871-879. doi: 10.5114/aoms.2017.70328. Epub 2017 Sep 26.
PubMed 30002707Rodriguez-Sanz D, Calvo-Lobo C, Unda-Solano F, Sanz-Corbalan I, Romero-Morales C, Lopez-Lopez D. Cervical Lateral Glide Neural Mobilization Is Effective in Treating Cervicobrachial Pain: A Randomized Waiting List Controlled Clinical Trial. Pain Med. 2017 Dec 1;18(12):2492-2503. doi: 10.1093/pm/pnx011.
PubMed 28340157Rodriguez-Sanz D, Lopez-Lopez D, Unda-Solano F, Romero-Morales C, Sanz-Corbalan I, Beltran-Alacreu H, Calvo-Lobo C. Effects of Median Nerve Neural Mobilization in Treating Cervicobrachial Pain: A Randomized Waiting List-Controlled Clinical Trial. Pain Pract. 2018 Apr;18(4):431-442. doi: 10.1111/papr.12614. Epub 2017 Nov 20.
PubMed 28734105Arumugam V, Selvam S, MacDermid JC. Radial nerve mobilization reduces lateral elbow pain and provides short-term relief in computer users. Open Orthop J. 2014 Oct 17;8:368-71. doi: 10.2174/1874325001408010368. eCollection 2014.
PubMed 25352930Lau YN, Ng J, Lee SY, Li LC, Kwan CM, Fan SM, Leung BPL, Lo CN. A brief report on the clinical trial on neural mobilization exercise for joint pain in patients with rheumatoid arthritis. Z Rheumatol. 2019 Jun;78(5):474-478. doi: 10.1007/s00393-018-0521-7.
PubMed 30112581Villafane JH, Cleland JA, Fernandez-de-Las-Penas C. The effectiveness of a manual therapy and exercise protocol in patients with thumb carpometacarpal osteoarthritis: a randomized controlled trial. J Orthop Sports Phys Ther. 2013 Apr;43(4):204-13. doi: 10.2519/jospt.2013.4524. Epub 2013 Mar 13.
PubMed 23485660
Study at a glance
From the registry record, last updated by the sponsor on 1 Aug 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of the Neural Mobilization on Upper Limb Functionality in Patients With Acquired Brain Injury: Randomized, Controlled, Multi-Centric, Single-Blind Clinical Trial
- ClinicalTrials.gov ID
- NCT04652934
- Acronym / sponsor ID
- HUFA CEIC 20/154
- Conditions
- Hemiplegia and Hemiparesis, Acquired Brain Injury
- Keywords
- Acquired Brain Injury, Hemiplegia, Neural Mobilization, Upper limb
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 24 participants (actual)
- Lead sponsor
- Vanesa AbuínUniversity, hospital or other
- Collaborators
- Universidad Europea de Madrid
- Study start
- 26 Jan 2022 (actual)
- Primary completion
- 28 Jul 2023 (actual)
- Study completion
- 28 Jul 2023 (actual)
- First posted
- 3 Dec 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The main objective:
To determine changes in physiological and structural properties of upper limb muscles with spasticity in patients with acquired brain injury after applying neural mobilization improving their functional performance, their participation in society and quality of life.
Hypothesis:
Peripheral nerve mobilizations performed with neurodynamic techniques in upper limb in patients with acquired brain injury, generate changes at structural and physiological level, favoring the performance of daily life activities and improving the quality of life.
Detailed description
Randomized clinical trial with blinding of the subject, the evaluator and the person analyzing the data.
In the experimental group will be performed neural mobilitazion technique, while in the sham a technique to mimic neurodynamic.
The assessment will be made by a single evaluator.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
- Model description
- Randomized Controlled Trial
| Arm | Type | Receives |
|---|---|---|
| Intervention group | Experimental | Other: NeurodynamicThe Upper Limb Neurodynamic Test (ULNT1) technique described by Butler will be performed on the affected limb. This technique consists of performing shoulder depression, 90º shoulder abduction, hand, wrist and forearm in a neutral position, external rotation of the shoulder and extension of the elbow. After positioning the limb in this position, wrist flexion-extension movements will be performed smoothly and rhythmically of 20 movements every minute, for 3 minutes, three times per session with 1 minute of rest between each series. |
| Mimic group | Sham comparator | Other: Mimic groupThe protocol used by Beneciuk et al. Will be used. This intervention consists of imitating NM without stressing the nervous system. It will be carried out as follow: a neutral cervical position will be maintained (0º of cervical inclination), 45º of shoulder abduction without depression, 45º of external rotation of the shoulder combined with 45º of elbow flexion with the forearm in pronation. Afterwards, 10 wrist flexion-extension movements will be performed at a rate of 6 seconds per cycle (3 seconds of flexion and 3 seconds of extension). The resistance that you will feel will stabilize when you change motion. Once the 10 cycles of movements have been carried out, a wrist flexion will be maintained for 10 seconds. |
Who may qualify
- Ages
- 25 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Diagnosis of acquired brain injury (hemiplegia-hemiparesis)
- Ages between 25 and 50 years
Key exclusion criteria (4 listed)
- Unable to understand and respond to verbal instructions
- Absence of voluntary movement in the upper limb
- Take medicine for spasticity
- Botulinum toxin infiltration in the last 6 months
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| NeurodynamicThe Upper Limb Neurodynamic Test (ULNT1) technique described by Butler will be performed on the affected limb. This technique consists of performing shoulder depression, 90º shoulder abduction, hand, wrist and forearm in a neutral position, external rotation of the shoulder and extension of the elbow. After positioning the limb in this position, wrist flexion-extension movements will be performed smoothly and rhythmically of 20 movements every minute, for 3 minutes, three times per session with 1 minute of rest between each series. | Other | Intervention group |
| Mimic groupThe protocol used by Beneciuk et al. Will be used. This intervention consists of imitating NM without stressing the nervous system. It will be carried out as follow: a neutral cervical position will be maintained (0º of cervical inclination), 45º of shoulder abduction without depression, 45º of external rotation of the shoulder combined with 45º of elbow flexion with the forearm in pronation. Afterwards, 10 wrist flexion-extension movements will be performed at a rate of 6 seconds per cycle (3 seconds of flexion and 3 seconds of extension). The resistance that you will feel will stabilize when you change motion. Once the 10 cycles of movements have been carried out, a wrist flexion will be maintained for 10 seconds. | Other | Mimic group |
Primary outcome
Changes in Manual Ability
Time frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Abilhand Scale; Score 0(worse outcome)-2(better outcome)
Changes in Muscle Spasticity
Time frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
MAS (Modified Ashworth Scale) 0 (better outcome) - 4 (worse outcome)
Changes in Muscle Strength
Time frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Dynamometer
Changes in Nervous Conduction
Time frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Delsys Trigno Avanti (surface eMG for non-invasive assessment of muscles)
Changes in Upper Limb Pain Perception
Time frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
EVA (Visual Analog Scale) 0 (worse outcome) - 10 (better outcome)
Changes in Upper Limb Pain to Pressure
Time frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)
Algometer
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Aug 2023.
- Background: PubMed 9233055The World Health report 1996--fighting disease, fostering development. World Health Forum. 1997;18(1):1-8.
- Background: PubMed 29165784Synnot A, Chau M, Pitt V, O'Connor D, Gruen RL, Wasiak J, Clavisi O, Pattuwage L, Phillips K. Interventions for managing skeletal muscle spasticity following traumatic brain injury. Cochrane Database Syst Rev. 2017 Nov 22;11(11):CD008929. doi: 10.1002/14651858.CD008929.pub2.
- Background: PubMed 28704626Basson A, Olivier B, Ellis R, Coppieters M, Stewart A, Mudzi W. The Effectiveness of Neural Mobilization for Neuromusculoskeletal Conditions: A Systematic Review and Meta-analysis. J Orthop Sports Phys Ther. 2017 Sep;47(9):593-615. doi: 10.2519/jospt.2017.7117. Epub 2017 Jul 13.
- Background: PubMed 30710858Martins C, Pereira R, Fernandes I, Martins J, Lopes T, Ramos L, Pacheco J, Silva AG. Neural gliding and neural tensioning differently impact flexibility, heat and pressure pain thresholds in asymptomatic subjects: A randomized, parallel and double-blind study. Phys Ther Sport. 2019 Mar;36:101-109. doi: 10.1016/j.ptsp.2019.01.008. Epub 2019 Jan 23.
- Background: PubMed 26481666Beltran-Alacreu H, Jimenez-Sanz L, Fernandez Carnero J, La Touche R. Comparison of Hypoalgesic Effects of Neural Stretching vs Neural Gliding: A Randomized Controlled Trial. J Manipulative Physiol Ther. 2015 Nov-Dec;38(9):644-652. doi: 10.1016/j.jmpt.2015.09.002. Epub 2015 Oct 23.
- Background: PubMed 30935325Almeida RS, Machado E, Yamato TP, Santos De Melo L, Nogueira LAC. Pragmatic neural tissue management improves short-term pain and disability in patients with sciatica: a single-arm clinical trial. J Man Manip Ther. 2019 Sep;27(4):208-214. doi: 10.1080/10669817.2019.1580420. Epub 2019 Feb 26.
- Background: PubMed 30664500Ayub A, Osama M, Ahmad S. Effects of active versus passive upper extremity neural mobilization combined with mechanical traction and joint mobilization in females with cervical radiculopathy: A randomized controlled trial. J Back Musculoskelet Rehabil. 2019;32(5):725-730. doi: 10.3233/BMR-170887.
- Background: PubMed 28453446Kim DG, Chung SH, Jung HB. The effects of neural mobilization on cervical radiculopathy patients' pain, disability, ROM, and deep flexor endurance. J Back Musculoskelet Rehabil. 2017 Sep 22;30(5):951-959. doi: 10.3233/BMR-140191.
- Background: PubMed 27623523Ferragut-Garcias A, Plaza-Manzano G, Rodriguez-Blanco C, Velasco-Roldan O, Pecos-Martin D, Oliva-Pascual-Vaca J, Llabres-Bennasar B, Oliva-Pascual-Vaca A. Effectiveness of a Treatment Involving Soft Tissue Techniques and/or Neural Mobilization Techniques in the Management of Tension-Type Headache: A Randomized Controlled Trial. Arch Phys Med Rehabil. 2017 Feb;98(2):211-219.e2. doi: 10.1016/j.apmr.2016.08.466. Epub 2016 Sep 10.
- Background: PubMed 30002707Sanz DR, Solano FU, Lopez DL, Corbalan IS, Morales CR, Lobo CC. Effectiveness of median nerve neural mobilization versus oral ibuprofen treatment in subjects who suffer from cervicobrachial pain: a randomized clinical trial. Arch Med Sci. 2018 Jun;14(4):871-879. doi: 10.5114/aoms.2017.70328. Epub 2017 Sep 26.
- Background: PubMed 28340157Rodriguez-Sanz D, Calvo-Lobo C, Unda-Solano F, Sanz-Corbalan I, Romero-Morales C, Lopez-Lopez D. Cervical Lateral Glide Neural Mobilization Is Effective in Treating Cervicobrachial Pain: A Randomized Waiting List Controlled Clinical Trial. Pain Med. 2017 Dec 1;18(12):2492-2503. doi: 10.1093/pm/pnx011.
- Background: PubMed 28734105Rodriguez-Sanz D, Lopez-Lopez D, Unda-Solano F, Romero-Morales C, Sanz-Corbalan I, Beltran-Alacreu H, Calvo-Lobo C. Effects of Median Nerve Neural Mobilization in Treating Cervicobrachial Pain: A Randomized Waiting List-Controlled Clinical Trial. Pain Pract. 2018 Apr;18(4):431-442. doi: 10.1111/papr.12614. Epub 2017 Nov 20.
- Las personas con Daño Cerebral Adquirido en EspañaLink provided by the sponsor.
- Neuropsicología Cognitiva. Aplicaciones a la clínica y a la investigación Fundamento teórico y metedológico de la Neuropsicología Cognitiva \[Internet\]. Madrid: Instituto de Migraciones y Servicios Sociales (IMSERSO)Link provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Vanesa Abuín, Dr study chair
Universidad Europea de Madrid
Leticia Martínez, Dr study director
Universidad Europea de Madrid
Almudena Buesa, Dr study chair
Universidad San Jorge de Zaragoza
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Neurodynamic and Mimic group in people with Hemiplegia and Hemiparesis and Acquired Brain Injury, run by Vanesa Abuín at 1 site in Spain.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 1 Aug 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Spain. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Changes in Manual Ability (time frame: Pre-intervention; Immediately after the intervention; Follow up (1 week after the intervention)). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04652934, which also lists 45 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Aug 2023.