Clinical trials: Upper Limb Surgery
Edema Limbs
Effects Neuromuscular Taping Technique on Upper Limbs Edema in Cardiac Surgery Patients
This study aims to verify the efficacy of the decompression technique of neuromuscular taping on cardiac surgery patients in whom edema of the upper limbs occurs due to post-operative water overload.
- Trial name
- NCT04785508
- Testing
- neuromuscolar tape, antigravity arm position
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Ameloblastoma, BRAF V600E Mutation Positive
Clinical Study of Neoadjuvant Targeted Therapy for Ameloblastoma
This study aims to evaluate the tumor shrinkage effect of preoperative targeted induction therapy with dabrafenib and trametinib in patients with conventional ameloblastoma harboring the BRAF V600E mutation.
- Trial name
- NETCAM (NCT06653517)
- Testing
- Dabrafenib, Trametinib
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Unilateral Cleft Lip, Nasoalveolar Molding
Nasolabial Soft Tissue Esthetics and Maxillary Changes in Unilateral Cleft Lip and Palate Using PreSurgical Infant Orthopedics With Different Approaches
The nasal deformity is an abnormality in the appearance and structure of the nose in cleft patients having unilateral cleft lip and palate (UCLP).
- Trial name
- PSIO (NCT05940389)
- Testing
- Naso Alveolar Mold, Taping with nasal elevator:
- Volunteers
- 24 people
- Sponsor
- Al-Azhar University
Wound Closure Technique, Wound Dehiscence, Surgical
Comparison of Cosmetic Outcome and Patient Satisfaction Between Staples and Suture Technique for Wound Closure Following Upper Limb Surgeries
Surgical wound closure is an essential component of postoperative care that influences wound healing, infection rates, cosmetic appearance, and patient satisfaction.
- Trial name
- NCT07633977
- Testing
- Staples, Sutures
- Where
- Nepal
- Volunteers
- 80 people
- Sponsor
- Kathmandu University School of Medical Sciences
Surgical Site Infection, Surgical Wound Infection
ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions
ROSSINI 2 is a phase III, multi-arm, multi-stage (MAMS) pragmatic, blinded (patient and outcome assessor), multicentre, randomised controlled trial (RCT) with an internal pilot, to evaluate the use of several in-theatre…
- Conditions
- Surgical Site Infection, Surgical Wound Infection, Surgery--Complications, Surgery
- Trial name
- ROSSINI 2 (NCT03838575)
- Testing
- 2% alcoholic chlorhexidine skin prep (SKIN PREP), Iodophor Antimicrobial Incise Drapes (DRAPE), Gentamicin-impregnated implants/ sponges (SPONGE)
- Where
- 2 sites in United Kingdom
- Volunteers
- 6,610 people
- Sponsor
- University of Birmingham
Minimal Invasive Surgery, Colon Surgery
The Anorectal Function and QoL of Patients Receiving Transrectal NOSE Via Rigid TAMIS Platform in Minimal Invasive Colon Surgery
The primary objective of this study is to prospectively determine and precisely estimate the incidence of Internal Anal Sphincter (IAS) Injury at 12 months following colectomy with Transrectal NOSE.
- Trial name
- NCT07653607
- Testing
- Pre-op and post-op anorectal function and quality of life evaluation
- Volunteers
- 57 people
- Sponsor
- Chang Gung Memorial Hospital
Shoulder Weakness Following Neck Dissection Surgery
A Study to Assess the Efficacy of Early Physical Therapy Intervention Following a Modified Unilateral Neck Dissection for Treatment of Head and Neck Cancer
This study will determine whether patients who receive regular physical therapy immediately following a modified neck dissection surgery will report decreased shoulder disability, decreased pain, improved or maintained shoulder…
- Trial name
- NCT01729065
- Testing
- Physical therapy intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Obstructive Sleep Apnea
Semi-up Right Position Study
Our main objective is to perform an explanatory, first stage proof of concept, randomized controlled trial to determine whether a semi-upright patient position versus a supine position while asleep in the postoperative period…
- Trial name
- NCT02152202
- Testing
- Semi-upright position, Supine position
- Where
- 4 sites in Canada
- Volunteers
- 164 people
- Sponsor
- University Health Network, Toronto
End Diastolic Velocity, Perfusion Index
Perfusion Index and End Diastolic Velocity Ratios as Predictors of Supraclavicular Block Success in Vascular Access Surgery
This is a prospective observational study investigating the correlation between Perfusion Index (PI) ratio and End Diastolic Velocity (EDV) ratio as early predictors of successful supraclavicular brachial plexus block (SCBPB) in…
- Trial name
- NCT07197281
- Volunteers
- 50 people
- Sponsor
- Assiut University
Thoracic Surgery
Effect of Digital Physiotherapy Practice on Pulmonary Function, Muscle Strength, Quality of Life After Thoracic Surgery
Thoracic surgery is the primary intervention used in the treatment of diseases affecting the lungs, pleura, chest wall, and mediastinum.
- Trial name
- NCT07133672
- Testing
- Exercise, Standard care
- Volunteers
- 26 people
- Sponsor
- Bezmialem Vakif University
Hemostasis
HEMOBLAST Pilot Clinical Investigation
The primary objective of this pilot clinical investigation is to assess the reliability of the Surface Bleeding Severity Scale (SBSS) in a clinical setting.
- Trial name
- NCT02502019
- Testing
- HEMOBLAST Bellows
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- Biom'Up France SAS
Esophageal Squamous Cell Carcinoma
Adjuvant Pembrolizumab for Patients With Locally Advanced Esophageal Squamous Cell Carcinoma at High Risk of Recurrence
In this study, participants with histologically diagnosed locally advanced esophageal squamous cell carcinoma who have received preoperative cisplatin-based chemoradiotherapy followed by surgery harbouring high risk of tumor…
- Trial name
- NCT03322267
- Testing
- Pembrolizumab
- Where
- Taiwan
- Volunteers
- 26 people
- Sponsor
- National Taiwan University Hospital
Tibial Fracture
Assessment of the Verus Frame in Tibial Intramedullary Nailing
This prospective, single-arm Post-Market Clinical Follow-Up (PMCF) study, utilizing a registry-based control group, will assess the Verus frame's effectiveness in achieving precise tibial rotation and alignment during…
- Trial name
- NCT07362121
- Testing
- Verus frame to stabilize tibia
- Where
- Finland
- Volunteers
- 25 people
- Sponsor
- Hemitec Finland Oy
Hemodynamics
Gradual Versus Intermittent Release of Tourniquet Effect on MAP in Hypertensive Patients Undergoing Upper Limb Orthopedic Surgeries
In this clinical trial, the authors will compare two tourniquet deflation techniques and their clinical implications on hemodynamics and acid base parameters in hypertensive orthopedic patients undergoing upper limb surgeries…
- Trial name
- NCT07290504
- Testing
- Tourniquet deflation
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Kasr El Aini Hospital
Gastrointestinal Stromal Tumor of Rectum
Preoperative Imatinib Mesylate Combined With Rectal-sparing Surgery in Patients With c-KIT Gene-mutant Rectal GIST
Prior to the implementation of preoperative imatinib mesylate therapy, a considerable percentage (ranging from 34.5% to 67.5%) of individuals diagnosed with rectal gastrointestinal stromal tumors (GIST) underwent abdominoperineal…
- Trial name
- PIRKER (NCT05970900)
- Testing
- Imatinib Mesylate, Local resection
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Fujian Medical University Union Hospital
Total Knee Replacement, Total Knee Replacement Surgery
Mako Cementless TKA vs Mako Cemented TKA
The overall aims of this prospective, randomised, single-blinded controlled trial are to compare functional, radiological and clinical outcomes in Mako robotic-arm assisted cementless Total Knee Arthroplasty (TKA) versus Mako…
- Conditions
- Total Knee Replacement, Total Knee Replacement Surgery, Total Knee Arthroplasty, Osteoarthritis (OA) of the Knee
- Trial name
- NCT06929871
- Testing
- Mako cementless TKA, Mako cemented TKA
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University College, London
Breast Cancer
Liposuction for Arm Lymphedema Following Breast Cancer Surgery
The purpose of this study is to determine if a less invasive procedure such as liposuction can be used to effectively reduce arm lymphedema (swelling of the arm) resulting from breast cancer treatment.
- Trial name
- NCT00816985
- Testing
- Liposuction, Quality of Life Questionnaires
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Cardiac Surgery, Central Venous Catheter Thrombosis
Continuous Heparin Infusion to Prevent Catheter-related Thrombosis
Catheter-related thrombosis could impair blood flow in the vein, block the central venous catheter, induce catheter-related infection or venous thromboembolism in the deep veins or pulmonary vessels, which furthermore progress…
- Conditions
- Cardiac Surgery, Central Venous Catheter Thrombosis, Heparin
- Trial name
- NCT04767113
- Testing
- Heparin sodium, Normal saline
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Guangdong Provincial People's Hospital
HCC
CT011 Autologous CAR-T Cells in Patients With Hepatocellular Carcinoma at Risk of Recurrence After Surgical Resection
A Single-arm, Open-label, Multicenter, Phase Ib Clinical Trial to Evaluate the Safety and Efficacy of CT011 Autologous CAR-T Cells in Patients with Hepatocellular Carcinoma at Risk of Recurrence after Surgical Resection.
- Trial name
- NCT06560827
- Testing
- CT011 CAR-GPC3 T Cells Injection
- Where
- 15 sites in China
- Volunteers
- 30 people
- Sponsor
- CARsgen Therapeutics Co., Ltd.
Peri-implant Inflammation, Peri-Implantitis and Peri-implant Mucositis
Effect of Different Non-surgical Treatment Approaches of Peri-implantitis
Peri-implantitis is a biofilm-associated pathological condition characterized by inflammation within the peri-implant mucosa, which leads to the progressive loss of the surrounding supporting bone tissue.
- Conditions
- Peri-implant Inflammation, Peri-Implantitis and Peri-implant Mucositis, Non-surgical Treatment
- Trial name
- NCT06730568
- Testing
- Submarginal mechanical instrumentation, Submarginal mechanical instrumentation and chlorhexidine irrigation, Submarginal mechanical instrumentation and ozone application
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Yeditepe University