Clinical trials: Upper Limb Surgery
Breast Cancer Female
Wide-field Optical Coherence Tomography Imaging of Excised Breast Tissue.
This is a single-arm, multi-center data collection study designed to collect WF-OCT imaging data of excised breast tissue margins with corresponding margin status from histopathology.
- Trial name
- NCT04242277
- Testing
- Investigational WF-OCT device
- Where
- 2 sites in United States
- Volunteers
- 198 people
- Sponsor
- Perimeter Medical Imaging
Brachial Plexus Block, Dexmedetomidine
Comparison Of Dexmedetomidine And Dexamethasone As An Adjuvant To Bupivacaine In Brachial Plexus Block
Brachial plexus block is a regional anaesthesia technique employed as a safe and valuable alternative to general anaesthesia for upper limb surgery.
- Conditions
- Brachial Plexus Block, Dexmedetomidine, Dexamethasone, Bupivacaine
- Trial name
- NCT04791475
- Testing
- adding Dexmedetomidine and dexamethasone to bupivacaine in USG guided supraclavicular brachial plexus block.
- Where
- Nepal
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Distal Radius Fracture
Minimally Invasive Fixation for Distal Radius Fractures
Minimally invasive surgery avoids the tissue damage and impairment of physiological function caused by open surgery because of its precise location techniques and can effectively promote the early recovery of wrist function.
- Trial name
- DRF (NCT05175118)
- Testing
- Minimal invasive surgical fixation of distal radius Fractures
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gastric Cancer, Gastric Adenocarcinoma
Feasibility Study of Middle Segmental Gastrectomy (MSG) for Gastric Cancer.
This multicenter, prospective, single-arm phase 2 clinical trial aims to evaluate the safety, feasibility, and clinical applicability of Middle Segmental Gastrectomy (MSG) for patients with gastric cancer MSG is a…
- Conditions
- Gastric Cancer, Gastric Adenocarcinoma, Middle Segmental Gastrectomy (MSG), Function-preserving Surgery
- Trial name
- MSG (NCT07899697)
- Testing
- Totally Laparoscopic Middle Segmental Gastrectomy (TLMSG)
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- National Cancer Center, Korea
Oral Surgery, Tooth Extraction
Assessment of DAFILON® Suture Material in Oral Surgery (Mucosal Sutures)
In this non-interventional study (NIS) a polyamide non-absorbable suture (Dafilon) will be evaluated for oral surgery (mucosal closure after e.g. wisdom teeth extraction, implant surgery, etc.) in adult patients
- Conditions
- Oral Surgery, Tooth Extraction, Dental Implants
- Trial name
- MUCODA (NCT04390620)
- Testing
- Mucosal Closure
- Where
- 2 sites in Germany, Spain
- Volunteers
- 105 people
- Sponsor
- Aesculap AG
Obesity/therapy
Rhomboid Intercostal Block with Subserratus Plane Block in Bariatric Surgery
Standard analgesic techniques such as patient-controlled analgesia (PCA) and continuous epidural analgesia (CEA) are effective but associated with considerable side effects, including nausea, hypotension, and respiratory…
- Trial name
- NCT06729515
- Testing
- PCA, CEA, RISS
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Xiaguang Duan
Nerve Block, Regional Anesthesia
Classic Versus Interfascial Axillary Block in Hand, Wrist, and Forearm Surgery
Hand, wrist, and forearm surgeries are commonly performed procedures with significant postoperative pain potential. Regional anesthesia of the brachial plexus via the axillary approach is one of the gold-standard techniques for…
- Conditions
- Nerve Block, Regional Anesthesia, Upper Extremity Surgery
- Trial name
- NCT07823738
- Testing
- Classic Axillary Block, Interfascial Axillary Block
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Intracranial Aneurysm, Transradial Access(TRA)
Application of Brachial Plexus Block in Patients Undergoing Cerebral Aneurysm Embolization Via Transradial Approach
The aim of this study was toinvestigate the effect of BPB on outcome of upper extremity arteries in patients undergoing interventional embolization of intracranial aneurysms via TRA.
- Trial name
- ABPBCAETRA (NCT06035692)
- Testing
- Ropivacaine
- Where
- China
- Volunteers
- 176 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Esophageal Squamous Cell Carcinoma
Immunotherapy Plus Anlotinib After Surgery for Esophageal Squamous Cell Cancer With Residual Tumor and Positive Lymph Nodes
The goal of this clinical trial is to learn whether postoperative immunotherapy combined with anlotinib can help prevent or delay cancer recurrence in adults aged 18 to 75 years with locally advanced esophageal squamous cell…
- Trial name
- NCT07830355
- Testing
- Anlotinib, Anti-PD-1 Monoclonal Antibody
- Volunteers
- 75 people
- Sponsor
- Shanghai Chest Hospital
Postoperative Cognitive Dysfunction
Feasibility Study of Preoperative Cognitive Training in Cardiac Surgical Patients
The purpose of this study is to evaluate the feasibility of administering a 20-day preoperative cognitive training intervention (Cog-Train) to a widely inclusive sample of cardiac surgical patients.
- Trial name
- Cog-Train (NCT02053207)
- Testing
- Cog-Train Intervention
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Peri Implantitis
Immediate Versus Delayed Surgical Reconstruction of Peri-implantitis Intra-bony Defects.
The purpose of this study is to test the comparative efficacy of two surgical approaches (immediate versus delayed GBR) for the surgical reconstruction of peri-implantitis intra-bony defects in terms of the clinical…
- Trial name
- NCT07325747
- Testing
- Staged peri-implant debridement and regeneration, Simultaneous peri-implant debridement and regeneration
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Gastrointestinal Function, Mental Well-being
The Effects of Early Postoperative Heat Application and Abdominal Massage on Gastrointestinal Function
This randomised controlled trial was designed to determine the effect of early-stage heat application and abdominal massage on patients' gastrointestinal function and mental well-being following hip fracture surgery.
- Trial name
- NCT07208955
- Testing
- heat application, abdominal massage, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Laceration, Incision
Optilene® Suture Material for Dermal Sutures
In this non-interventional study, Optilene® suture will be evaluated for skin closure in adult patients.
- Trial name
- OPTIDERMAL (NCT05240248)
- Where
- Spain
- Volunteers
- 172 people
- Sponsor
- Aesculap AG
Fracture, Trauma
Surgical Treatment Versus Non-surgical Treatment of Ulnar Fractures
The purpose of this study is to determine if surgery using a plate and screws to fix a forearm fracture (ulnar shaft) will improve functional outcome compared to non-operative treatment out to 1 year of follow-up.
- Conditions
- Fracture, Trauma, Ulna Fracture, Orthopedic
- Trial name
- NCT01123447
- Testing
- Open reduction and internal fixation, Closed reduction and short-arm cast
- Where
- 9 sites in Canada, United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Solid Tumor Malignancy
Efficacy and Safety of Pemigatinib in Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)
The purpose of this study is to evaluate the efficacy and safety of pemigatinib in participants with previously treated locally advanced/metastatic or surgically unresectable solid tumor malignancies harboring activating FGFR…
- Trial name
- NCT03822117
- Testing
- Pemigatinib
- Where
- 90 sites in United States, Denmark and 9 more
- Volunteers
- 111 people
- Sponsor
- Incyte Corporation
Breast Cancer Surgery, Transcutaneous Electric Nerve Stimulation
Effects of Transcutaneous Electrical Nerve Stimulation on Breast Surgery
The aim of this randomized controlled trial was to evaluate the effects of transcutaneous electrical nerve stimulation (TENS) on postoperative pain, lymphedema development, shoulder range of motion, and quality of life in women…
- Trial name
- NCT06973265
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Seda Akutay
Post-operative Pain, Upper Limb Surgery
Lidocaine vs. Lidocaine With Dexmedetomidine for Intravenous Regional Anesthesia (IVRA) in Upper Limb Surgery
This study compares lidocaine alone vs. lidocaine with dexmedetomidine in Intravenous regional anesthesia (IVRA) for upper limb surgery in terms of pain scores and duration of analgesia
- Conditions
- Post-operative Pain, Upper Limb Surgery, Regional Anesthesia
- Trial name
- NCT07034300
- Testing
- Lidocaine (drug), Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Fatima Memorial Hospital
Breast Neoplasms
Upper Limb Function After Breast Cancer Surgery: the Role of Post-operative Physical Therapy Intervention
Surgical treatments can cause late effects influencing activity of daily living, physical activity, and overall health. Late effects include persistent pain reported by 30 - 50% of women that underwent breast operations…
- Trial name
- NCT03389204
- Testing
- PHYSICAL THERAPY
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Assuta Medical Center
Temperament, Trauma (Including Fractures)
How Personality Type Affects Pain and the Need for General Anesthesia in Patients Receiving an Arm Nerve Block for Wrist Fracture Surgery
This study looked at whether a person's emotional personality type affects how they experience pain and how well a regional anesthesia technique works during arm surgery.
- Trial name
- NCT07450768
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Male Circumcision, HIV Prevention
Follow Up Study to Evaluate a Non-Surgical Device for Adult Male Circumcision for Screen Failure Subjects
It is well known from a range of observational and epidemiological studies that the lifetime risk of acquiring HIV among males can be significantly reduced via circumcision by 53%-60% and by up to 73% in post-trial observation.
- Conditions
- Male Circumcision, HIV Prevention, Screen Failure Subjects, Narrow Foreskin
- Trial name
- RMC-05 (NCT02281435)
- Testing
- PrePex™ device
- Where
- Rwanda
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda