Clinical trials: Upper Limbs
Amputation of Upper Limb Below Elbow, Prosthesis User
Effect of Motor Imagery Ability on Functionality and Proprioception in Amputees Using Myoelectric Prostheses"
The purpose of this study is to evaluate the motor imagery ability in transradial amputees using myoelectric prosthesis, compare it with the control group and investigate its effect on functionality and proprioception.
- Trial name
- NCT06541379
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medipol University
Upper Limb Overuse Syndrome
Elongation Longitudinal Decoaptation Ostéo-Articulaire Versus Active Isolated Stretching on Median Nerve Mobility and Pain in Patient With Upper Limb Overuse Syndrome
Upper-limb overuse syndrome (ULOS) often arises from repetitive loading, altering cervical biomechanics and increased median-nerve mechano sensitivity.
- Trial name
- NCT07703332
- Testing
- Elongation longitudinal decoaptation ostéo-articulaire (ELDOA) and baseline, Active isolated stretching (AIS)
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- University of Faisalabad
Lymphedema, Lymphedema Arm
Screening For BCRL In Targeted Therapy For Breast Cancer
This a prospective, longitudinal study designed to track edema and Breast Cancer Related Lymphedema (BCRL) onset in breast cancer patients taking targeted therapy treatments for early and metastatic breast cancer.
- Conditions
- Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Lymphedema of Upper Limb
- Trial name
- NCT05142800
- Testing
- Perometer, SOZO device
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- Massachusetts General Hospital
Upper Limb Spasticity
A Study to Compare the Safety and Efficacy of Dysport® and Botox® in Adults With Upper Limb Spasticity.
This study is aiming to demonstrate the non-inferiority of AbobotulinumtoxinA (aboBoNT-A) versus OnabotulinumtoxinA (onaBoNT-A) as the primary safety endpoint, and the superiority of aboBoNT-A over onaBoNT-A with respect to…
- Trial name
- DIRECTION (NCT04936542)
- Testing
- AboBoNT-A, OnaBoNT-A
- Where
- 76 sites in United States, Canada and 2 more
- Volunteers
- 464 people
- Sponsor
- Ipsen
Upper Limb Amputation, Healthy Subjects
Microneurography and Intraneural Microstimulation for Upper Limb Sensory Investigation in Healthy and Amputee Subjects
The goal of this experimental study is to investigate the somatosensory system through intraneural recording and stimulation of the median nerve in healthy volunteers and participants with upper-limb amputation.
- Trial name
- MICROAMP (NCT07691957)
- Testing
- Microneurography, Intraneural Microstimulation
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Stroke, Spastic Hemiplegia
Robot-assisted Versus Conventional Physical Therapy for Hand in Sub-acute Stroke
This randomized controlled trial aims to compare the effectiveness of robotic-assisted physiotherapy and conventional physiotherapy in improving hand function among patients with sub-acute stroke.
- Conditions
- Stroke, Spastic Hemiplegia, Upper Limb Motor Impairment
- Trial name
- ROCHAS (NCT07615569)
- Testing
- Robotic-Assisted Hand Rehabilitation Therapy, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Montiha Azeem
Upper Limb Amputation, Postural Control
The Relationship Between Lost Extremity Percentage and Postural Control, Neck and Low Back Pain, Daily Living Activities, and Reaction Time in Individuals With Unilateral Upper Limb Amputation
This observational study aims to examine the relationship between the percentage of limb loss and functional outcomes in individuals with unilateral upper limb amputation.
- Conditions
- Upper Limb Amputation, Postural Control, Neck Pain, Low Back Pain
- Trial name
- NCT07677969
- Testing
- This is an observational study. No interventional procedures are performed. All assessments are non-invasive measurements.
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Hacettepe University
Upper Limb Strength, Upper Limb Power
Effect of Upper-limb Plyometric Training Versus Strength Training for Enhancing Serve Velocity, Strength, and Power in Competitive Tennis Players
This study aims to compare the effects of upper-limb plyometric training and traditional strength training on serve velocity, muscular strength, and power in competitive tennis players.
- Conditions
- Upper Limb Strength, Upper Limb Power, Upper Limb Serve Velocity
- Trial name
- ULPT-ST (NCT07584941)
- Testing
- Upper limb Plyometric Training, Conventional Strength Training
- Where
- Pakistan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Ibadat International University, Islamabad
Upper Limb Amputation Below Elbow (Injury), Wrist Disarticulation
Evaluation of the Phantom X Implantable EMG Sensor System for Myoelectric Prosthesis Control
The CYBORG Study is a first-in-human clinical investigation evaluating the safety and performance of the Phantom X System, an implantable electromyography (EMG) sensor array designed to provide control of upper-limb prostheses.
- Conditions
- Upper Limb Amputation Below Elbow (Injury), Wrist Disarticulation, Transradial Amputation
- Trial name
- CYBORG (NCT07325708)
- Testing
- Phantom X multielectrode EMG sensor array implant for upper limb prosthesis control
- Where
- 2 sites in Australia
- Volunteers
- 10 people
- Sponsor
- Phantom Neuro Inc.
Amputation of Upper Limb, Agenesis of Upper Limb
Using Sensorimotor Reorganization Following Upper Limb Amputation to Improve Prosthetic Control
Amputation of an upper limb results in a disruption of the sensorimotor loop and a reorganization of the nervous system, leading to the emergence of a phantom limb and the adaptation of compensatory motor strategies.
- Trial name
- REINVENT (NCT07666204)
- Testing
- Caracterisation, Mapping, Phantom sensations
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Upper Limb Rehabilitation
Exoneuromusculoskeleton for Upper Limb Rehabilitation After Stroke
A new clothing robotic arm was developed for multi-joint coordinated upper limb rehabilitation after stroke. Patients after stroke will be recruited to evaluate the rehabilitation effectiveness of the device assisted upper limb…
- Trial name
- NCT03752775
- Testing
- Robot assisted upper limb rehabilitation
- Where
- China
- Volunteers
- 45 people
- Sponsor
- The Hong Kong Polytechnic University
Complex Regional Pain Syndrome Type I of the Upper Limb
Contribution of Immersive Virtual Reality to a Standardized Rehabilitation Program for Upper Limb Chronic Pain: A Single-Case Experimental Design Study
Background: Chronic pain represents a significant public health concern, given its high prevalence and the substantial impact it has on the quality of life of many individuals affected.
- Trial name
- ReVIDoC (NCT06523361)
- Testing
- H'ability
- Where
- 2 sites in France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Angers
Upper Limb Ischemia, Stroke
Identification of Non-motor Brain Areas Involved in Upper Limb Motor Recovery After Stroke
Why: Upper-limb recovery post-stroke is challenging. Rehabilitation, aiming to induce plasticity takes an important place in patients' treatment.
- Trial name
- NOMO-Stroke (NCT05313776)
- Testing
- Magnetic Resonance Imaging
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Post-stroke Upper Limb Hemiparesis, Repetitive Transcranial Magnetic Stimulation (rTMS)
Repetitive Transcranial Magnetic Stimulation Combined With Bimanual Therapy for Upper Limb Stroke Rehabilitation
The goal of this clinical trial is to evaluate whether combining repetitive transcranial magnetic stimulation (rTMS) with machine-assisted bimanual therapy (BT) can improve upper limb function in stroke patients.
- Conditions
- Post-stroke Upper Limb Hemiparesis, Repetitive Transcranial Magnetic Stimulation (rTMS), Bimanual Therapy, Neuromodulation
- Trial name
- NCT07054424
- Testing
- Conventional occupation therapy, stretching exercise, rTMS
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- Chang Gung Memorial Hospital
Upper Limb Deficit, Stroke Gait Rehabilitation
Impact of VNS With Rehab on Gait Post-Stroke
This is a prospective, double-blinded, randomized controlled study to evaluate the impact of Vagus Nerve Stimulation (VNS) therapy on lower limb function.
- Conditions
- Upper Limb Deficit, Stroke Gait Rehabilitation, Stroke
- Trial name
- NCT07643337
- Testing
- Vagus Nerve Stimulation Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- State University of New York at Buffalo
Cerebral Palsy (CP), Spastic Quadriplegia
Impact of Task-Specific Electrical Stimulation on Upper Limb Functional Motor Skills in Children With Spastic Quadriplegia
Cerebral palsy is a non-progressive lesion of the brain occurring before 2 years of age resulting in disorders of posture and movement.( Ostensjo S, 2004)( Keles MN, 2018) .
- Conditions
- Cerebral Palsy (CP), Spastic Quadriplegia, Upper Limb Function, Functional Motor Disorder
- Trial name
- NCT07631390
- Testing
- The Chattanooga Continuum™, Designed Physical therapy program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University
Chonic Stroke Patients With Motor Impairment of Upper Limb
Impact of rTMS on BCI Control in Upper Limb Motor Rehabilitation of Patients With Chronic Stroke
Cerebrovascular accidents (strokes) are a major public health issue. Stroke is the 3rd leading cause of death and the leading cause of disability and loss of autonomy.
- Trial name
- BCINET (NCT06951035)
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Wrist Injuries, Hand and Upper Limb Trauma
Virtual Reality Therapy for Wrist and Hand Injury Recovery
The goal of this randomized clinical trial is to find out whether an early neuro-functional rehabilitation program using virtual reality and action observation can improve recovery after a traumatic injury of the wrist or hand…
- Conditions
- Wrist Injuries, Hand and Upper Limb Trauma, Muskuloskeletan Pain
- Trial name
- AOT+VR (NCT07408622)
- Testing
- Virtual reality
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- University of Malaga
Wrist Injury, Hand and Upper Limb Trauma
Cortical Changes After Upper Limb Immobilization Measured by Electroencephalography
This study aims to investigate how temporary immobilization of the upper limb after injury affects brain activity and functional recovery.
- Conditions
- Wrist Injury, Hand and Upper Limb Trauma, Muskuloskeletal Diseases
- Trial name
- EEG (NCT07428304)
- Testing
- Orthopedic Immobilization, Standard Rehabilitation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Malaga
Post-stroke Spasticity of the Upper Limb
TMS AND BOTULINUM TOXIN IN POST-STROKE UPPER LIMB SPASTICITY
Post-stroke upper limb spasticity is an important condition that negatively affects motor recovery, upper limb functions, and activities of daily living.
- Trial name
- TMS (NCT07624149)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Continuous Theta Burst Stimulation (cTBS)
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Asya ÖZCAN KAVCI