Clinical trials: Upper Motor Neuron Lesion
Cerebral Palsy
Whole Body Vibration in Rehabilitation of Spastic Cerebral Palsy
Spasticity is one of the most common features in children with cerebral palsy (CP) and is evident in the majority of CP types such as hemiplegia, diplegia, quadriplegia, etc.
- Trial name
- WBV (NCT06077136)
- Testing
- whole body vibration, standard physical therapy
- Where
- Saudi Arabia
- Volunteers
- 56 people
- Sponsor
- University of Hail
Spinal Cord Injuries
Reciprocal Inhibition Versus Reciprocal Facilitation In Spinal Cord Injury Patients
Reciprocal inhibition is a medulla spinalis control mechanism that facilitates motor activities in healthy people. As the agonist muscle contracts, the antagonist muscle is inhibited so that the agonist action can take place…
- Trial name
- NCT05985031
- Testing
- Tendon tap, Tibial nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Chronic Pain, Spasticity as Sequela of Stroke
Closed Loop Spinal Cord Stimulation for Neuromodulation of Upper Motor Neuron Lesion Spasticity
Spasticity is characterized by increased muscle tension and is a classic consequence of upper motor neuron (UMN) damage in the central nervous system, such as from stroke or trauma.
- Conditions
- Chronic Pain, Spasticity as Sequela of Stroke, Upper Motor Neuron Lesion
- Trial name
- CLONUS (NCT06384170)
- Testing
- Spinal Cord Stimulation- Closed loop
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Pyramidal Tract-related Spasticity, Upper Motor Neuron Lesion
The Effectiveness of Different Pulse Duration of NMES in Patients With Pyramidal Tract-related Spasticity Measured by Neurophysiological Tools
Spasticity is a common symptom that affects more than 50% of patients with upper motor neuron lesions due to damage on pyramidal tract.
- Trial name
- PD-NMES-SPAS (NCT07321158)
- Testing
- High Pulse Duration Neuromuscular Electrical Stimulation Group, Low Pulse Duration Neuromuscular Electrical Stimulation Group, Usual Care Group
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- University of West Attica
Spinal Cord Injury(SCI)
Effects of Continuous Passive Motion on the Spinal Circuitries and Its Adaptation in Patients With Spasticity Resulting From Upper Motor Neuron Lesions
In animal and human studies, histochemical and physiological evidences showed that the muscle transferred from slow, fatigue-resistant muscle to fast, fatigable muscle after spinal cord injury.
- Trial name
- NCT02122276
- Testing
- Ankle continuous passive motion machine.
- Where
- Taiwan
- Volunteers
- 7 people
- Sponsor
- Chang Gung University
Child Development, Upper Motor Neurone Lesion
Validity and Reliability of the PROprioception Measurement Tool (PROMT)
This project assesses the feasibility, reliability, and validity of the PROMT in children with a UMN lesion. The study questions are: is the newly developed PROMT a feasible, reliable, and valid tool to assess lower limb…
- Conditions
- Child Development, Upper Motor Neurone Lesion, Cerebral Palsy, Proprioceptive Disorders
- Trial name
- PROMT (NCT05405881)
- Testing
- Proprioception measurement tool
- Where
- Switzerland
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Multiple Sclerosis, Mindfulness
The Effect of a Mindfulness-Based Stress Reduction Program in Patients With Multiple Sclerosis
The aim of this study is to investigate the effect of an mindfulness-based stress reduction (MBSR) program designed in accordance with the literature and the basic principles of the program on fatigue, self-efficacy and stress…
- Conditions
- Multiple Sclerosis, Mindfulness, Upper Motor Neuron Lesion
- Trial name
- NCT06416176
- Testing
- Mindfulness-Based Stress Reduction (MBSR) Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Halic University