Clinical trials: Uremic; Toxemia
CKD (Chronic Kidney Disease) Stage 5D, Uremia; Chronic
Studies on Adsorption International Learning Initiative Global
Use of sorption technologies in patients undergoing maintenance hemodialysis with inflammatory syndrome and clinical manifestations of uremia
- Conditions
- CKD (Chronic Kidney Disease) Stage 5D, Uremia; Chronic, Uremic; Toxemia, Inflammation Chronic
- Trial name
- SAILING (NCT07123909)
- Testing
- Patients will undergo a combined hemodialysis and hemosorption procedure. The study cartridge for hemosorption by Jafron HA130 contains the original adsorbing material.
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Botkin Hospital
Acute Kidney Injury, Septic Shock
Prognostic Value Serum Concentration of Indoxyl Sulfate During Acute Kidney Injury in Septic Shock Patients.
The development of acute kidney injury (AKI) during septic shock is frequent and is associated with a high mortality rate. The reason of this increased mortality despite the use of renal replacement therapy is still unknown.
- Conditions
- Acute Kidney Injury, Septic Shock, Uremic; Toxemia, Mortality
- Trial name
- TOX-AKI (NCT03920982)
- Testing
- Determination of the blood concentration of indoxyl sulfate (IS)
- Where
- France
- Volunteers
- 114 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Acute Kidney Injury, Uremic; Toxemia
Prognostic Role of the Uremic Toxin Indoxyl Sulfate on Vascular and Cardiac Functions During Acute Kidney Injury
Acute kidney injury (AKI) is a frequent disease in conventional hospital departments and in intensive care units. It's associated with a high risk to develop chronic kidney disease (CKD), even after a single small AKI episode.
- Conditions
- Acute Kidney Injury, Uremic; Toxemia, Vascular Dysfunction, Cardiac Dysfunction
- Trial name
- VASC-AKI (NCT05659589)
- Testing
- blood sample
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Uremic; Toxemia
A Comparison of Protein-bound and Large Molecular Weight Uremic Toxin Removals With Novel Super High-flux Dialyzer Between Hemodialysis and High Volume Online HDF Modalities
The goal of this prospective, randomized, crossover study is to study about using super high-flux dialyzer in the chronic hemodialysis patients.
- Trial name
- NCT06567483
- Testing
- ELISIO21HX
- Where
- Thailand
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Albumin, Dialysis
Functionality of Albumin in the Context of Hemodialysis
Hemodialysis treatment enables patients with end-stage chronic kidney disease to survive. At the same time, however, this treatment also increases cardiovascular mortality, in particular due to a chronically increased level of…
- Conditions
- Albumin, Dialysis, Redox State, Uremic; Toxemia
- Trial name
- FACED (NCT06561191)
- Testing
- Hemodialysis mode, dialyzer type
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Universität Duisburg-Essen
Uremic; Toxemia, Pharmacokinetics
Toxicokinetics of Protein-bound Uremic Toxins in ESRD Patients
Protein-bound uremic toxins (PBUTs) are important uremic toxins, represented by indoxyl sulfate (IS), derived from the fermentation of dietary proteins by gut bacteria.
- Conditions
- Uremic; Toxemia, Pharmacokinetics, Renal Dialysis
- Trial name
- NCT05755503
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Kidney Transplant, Immunosuppression
Evaluation of Interaction Between Immunosuppressive Drugs and Protein-bound Uremic Toxins in Renal Transplant Patients
The majority of studies conducted on uremic toxins involve patients before end stage renal failure or dialysis patients. Only a few studies have focused on transplant patients.
- Conditions
- Kidney Transplant, Immunosuppression, Uremic; Toxemia
- Trial name
- DRUGTOX (NCT04963673)
- Testing
- calcineurin inhibitor dosage
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hemodialysis Complication, Inflammation
Toxins Removal and Inflammatory State modulAtion During Online Hemodiafiltration: Comparison of Two Different Dialyzers
The primary goal of the study is to evaluate in patients on three times a week on-line HDF the efficacy, in terms of toxin removal and modulation of the inflammatory state, of two different dialyzers: Helixone versus Asimmetric…
- Conditions
- Hemodialysis Complication, Inflammation, Uremic; Toxemia
- Trial name
- TRIAD2 (NCT04554498)
- Testing
- 1) high flux hemodiafiltration thrice -weekly during a 24 month follow-up
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna