Clinical trials: Ureter Obstruction
Ureteral Obstruction
Comparison of Dynamic Contrast Enhanced CT and Diuretic Renogram in The Evaluation of UPJO
Renal blood flow is inversely related to obstruction. We propose that this imaging will be as effective as the diuretic renogram in the functional diagnosis of obstruction.
- Trial name
- NCT00199472
- Testing
- Dynamic Contrast Enhanced CT & Diuretic Renogram
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Ureteral Obstruction
The RELIEF™ Ureteral Stent - Assessment of Retrograde Urinary Reflux and Distal Coil Bladder Position
Traditional ureteral stents are commonly used in renal and ureteral procedures, and their use is associated with many morbidities which can affect patients' quality of life.
- Trial name
- NCT03266770
- Testing
- RELIEF Stent
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University Hospitals Cleveland Medical Center
Ureteral Calculi, Hydronephrosis
Evaluating Ureteral Length Using Computed Tomography (CT)
Proper selection of ureteral stent length might help in reducing comorbidities associated with ureteral stenting, currently there is no standardized way of measuring ureteral length.
- Conditions
- Ureteral Calculi, Hydronephrosis, Ureteral Obstruction
- Trial name
- URO-Y-2 (NCT01542593)
- Testing
- Ureteral catheterization - Cook Urological Inc. open end ureteral catheter 5FR
- Where
- Israel
- Volunteers
- 53 people
- Sponsor
- Carmel Medical Center
Urolithiasis, Urologic Diseases
Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or…
- Conditions
- Urolithiasis, Urologic Diseases, Urinary Calculi, Urinary Obstruction
- Trial name
- STONE (NCT04594161)
- Testing
- Percutaneous Nephrostomy, Double J catheter
- Where
- Netherlands
- Volunteers
- 204 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Ureteral Obstruction, Stricture Ureter
Use of SPY Fluorescent Angiography to Reduce Ureteroenteric Stricture Rate Following Urinary Diversion
Ureteroenteric anastomotic stricture is a well-known complication of urinary diversion which occurs in 4-25% of patients. Recent study has yielded that radiation is a significant risk factor for development of ureteroenteric…
- Trial name
- NCT05022199
- Testing
- SPY fluorescent angiography
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
Urinary Tract Infection, Kidney Diseases
A Randomized Control Trial Comparing Single vs. Multiple Application of Lidocaine Analgesia Prior to Urethral Catheterization Procedures
The purpose of this study is to determine if a single application of Lidocaine gel topical anesthesia is as effective in decreasing the discomfort associated with urinary catheterization as two applications, within our pediatric…
- Conditions
- Urinary Tract Infection, Kidney Diseases, Ureteral Diseases, Ureteral Obstruction
- Trial name
- NCT00142064
- Testing
- observed levels of pain
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Ureter Stone, Quality of Life
Trospium Chloride vs Tamsulosin in Treatment of Ureteral Stent Related Symptoms:
This study will be conducted to compare the efficacy and safety of Trospium chloride versus Tamsulosin for treatment of ureteral stent related symptoms.
- Conditions
- Ureter Stone, Quality of Life, Ureter Obstruction
- Trial name
- NCT03709992
- Testing
- Trospium Chloride, Tamsulosin
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mansoura University
Kidney Stone, Ureter Obstruction
Is it Safe to Advance a Guidewire Through a Previously Placed Double j Stent?
In this prospective randomized controlled study, it is aimed to investigate the effects of guidewire advanced through a previously placed double j stent on postoperative complications, operation time and efficacy.
- Conditions
- Kidney Stone, Ureter Obstruction, Stent Complication
- Trial name
- NCT05265936
- Testing
- Passing a guidewire through a double j stent, Double J stent removal and guidewire insertion
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Ankara Training and Research Hospital
Erector Spinae Plane Block, Paravertebral Block
ESPB vs PVB vs QLB After Pelvi-ureteric Surgeries
The aim of this study is to compare the analgesic efficacy of erector spinae plane block versus thoracic paravertebral block versus quadratus lumborum block on postoperative analgesia after pelvi-ureteric surgeries.
- Conditions
- Erector Spinae Plane Block, Paravertebral Block, Quadratus Lumborum Block, Analgesia
- Trial name
- NCT05713643
- Testing
- ESPB Technique, TPVB Technique, QLB Technique
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Kafrelsheikh University
Ureteral Obstruction, Neoplasms
Antibiotic Prophylaxis in Percutaneous Nephrostomy Placements and Replacements for Malignant Urinary Tract Obstruction
This study aims to find out whether taking antibiotics to prevent a urinary tract infection after a medical procedure called percutaneous nephrostomy (placement of a catheter directly into the kidney to keep it working after the…
- Conditions
- Ureteral Obstruction, Neoplasms, Acute Kidney Injury, Nephrostomy; Complications
- Trial name
- NCT06801405
- Testing
- antibiotic prophylaxis
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- Barretos Cancer Hospital
Ureteral Obstruction
Laparoscopic Pyeloplasty Registry and Database
The gold standard for the treatment of ureteropelvic junction obstruction (UPJO) is the open pyeloplasty. As a minimally invasive alternative, many centers are currently offering laparoscopic pyeloplasty (LP) as primary therapy…
- Trial name
- NCT00169650
- Testing
- Registry and database
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Indiana Kidney Stone Institute
Ureteral Stricture, Ureteral Obstruction
An Integrated Multi-omics Study on the Molecular Mechanisms of Ureteral Stricture
The goal of this observational study is to investigate the systemic pathogenesis and identify potential diagnostic biomarkers in patients with ureteral stricture and healthy volunteers.
- Conditions
- Ureteral Stricture, Ureteral Obstruction, Microbiome, Metabolomics
- Trial name
- US-MOP (NCT07409870)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Ureteral Obstruction
Tolerance and Effectiveness of Ureteral Stents MEMOKATH ® 051 in Chronic Strictures of the Ureter
TOTEME offers to treat certain chronic strictures of the ureter with MEMOKATH 051 to assess its effectiveness, tolerance and mean durability during a 3 years follow up period.
- Trial name
- TOTEME (NCT00790686)
- Testing
- Insertion of Memokath 051
- Where
- 4 sites in France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Bordeaux
Ureteric Calculus, Sepsis
Percutaneous Nephrostomy Versus Stent In Sepsis Trial
Randomized control trial to compare the efficacy and safety of percutaneous nephrostomy with retrograde ureteric stenting for emergency renal decompression in cases of obstruction and sepsis associated with ureteric calculi.
- Conditions
- Ureteric Calculus, Sepsis, Hydronephrosis
- Trial name
- PERSIST (NCT02929160)
- Testing
- Percutaneous nephrostomy, Retrograde ureteric JJ stent
- Where
- 2 sites in Ireland
- Sponsor
- The Adelaide and Meath Hospital, incorporating The National Children's Hospital
Ureter Obstruction
Double-J PLUS Postmarket Registry Study
A multi-center global registry to obtain post-market safety and efficacy data on Boston Scientific Ureteral and Urinary Diversion Stents
- Trial name
- NCT04197583
- Testing
- Boston Scientific Ureteral Stents, Urinary Diversion Stent
- Where
- 10 sites in United States, Canada and 2 more
- Volunteers
- 379 people
- Sponsor
- Boston Scientific Corporation
Obstructive Uropathy, Hydronephrosis
Safety and Efficacy of Ultrasound-Guided Percutaneous Nephrostomy in Oncology Patients
Obstructive uropathy is a serious complication frequently seen in cancer patients, occurring when urine flow from the kidneys is blocked by tumor compression, invasion, or benign etiologies such as radiation-induced strictures…
- Conditions
- Obstructive Uropathy, Hydronephrosis, Ureteral Obstruction, Acute Kidney Injury
- Trial name
- NCT07855666
- Testing
- Ultrasound-guided percutaneous nephrostomy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Renal Calculi, Ureteral Obstruction
Assessment of Drug-eluting Ureteral Stent on Bacterial Adherence and Biofilm Formation
The purpose of this study is to determine the clinical effects of a triclosan stent on adherent bacteria, stent biofilms, and patient urine cultures in patients with an indwelling triclosan ureteral stent.
- Trial name
- NCT00250406
- Testing
- Ureteral Stent
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hydronephrosis; Obstruction, Ureter, Renal Failure
Tandem Polyurethane Stents Compared to Single Silicone Stent for Malignant Ureteral Obstruction
Malignant ureteral obstruction (MUO) is an extrinsic ureteral obstruction caused by malignant diseases. This study aim to compare tandem 6 Fr Percuflex™ stents and single large-caliber 8Fr silicone stent in patients with MUO.
- Conditions
- Hydronephrosis; Obstruction, Ureter, Renal Failure, Malignancy, Ureter Obstruction
- Trial name
- TSTENT (NCT05992363)
- Testing
- ureteral stent\s insertion
- Where
- 2 sites in Israel
- Volunteers
- 106 people
- Sponsor
- Rabin Medical Center
Cancer, Urinary Obstruction
Obstruction of Malignancy: Percutaneous Renal vs Endoscopic Stent
This research study will compare two procedures commonly used to treat urinary obstruction due to cancer. Sometimes cancer blocks one or both ureters (narrow tubes in the body that carry urine from the kidneys to the bladder).
- Conditions
- Cancer, Urinary Obstruction, Malignancy, Urinary Dysfunction
- Trial name
- NCT05640115
- Testing
- Ureteral Stent, Percutaneous Nephrostomy Tube Placement
- Where
- United States
- Sponsor
- University of Chicago