Clinical trials: Ureteral Diseases
Unilateral Ureteral Stone, Renal Stone Fragments ≤ 2mm
Feasibility Study of the Uriprene Stent Following Uncomplicated Ureteroscopy
A prospective, single-center, single-arm, trial to demonstrate safety and device performance of the ADVA-Tec Uriprene™ Degradable Temporary Ureteral Stent. This is a first-in-man clinical study in a small human population.
- Trial name
- URIPRENE (NCT02032316)
- Testing
- Post-Ureteroscopy ADVA-Tec Uriprene™ Degradable Temporary Ureteral Stent
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Adva-Tec
Ureteral Stent-Related Symptom, Urinary Tract Infections
Uroial Plus in the Management of Infections and Urinary Symptoms Associated With Ureteral Stents
Double-blind randomised interventional pilot study. To evaluate whether therapy with UroialTM Plus has a role in rebalancing homeostasis in ureteral stent patients, improving symptoms related to the presence of the ureteral stent…
- Trial name
- USSIAL (NCT06251336)
- Testing
- UroialTM Plus
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Distal Ureteral Stone, Urolithiasis
L-Citrulline Versus Tamsulosin for Medical Expulsive Therapy of Distal Ureteral Stones
This study will compare L-citrulline and tamsulosin as medical expulsive therapy for adults with single distal ureteral stones. Eligible participants with a single distal ureteral stone measuring 5 to 10 mm will be randomly…
- Conditions
- Distal Ureteral Stone, Urolithiasis, Ureteral Calculi
- Trial name
- NCT07617909
- Testing
- L-Citrulline, Tamsulosin
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Beni-Suef University
Kidney Calculi, Nephrolithiasis
Comparison of Suction and Conventional Ureteral Access Sheaths in Kidney Stone Surgery
The goal of this observational study is to compare conventional and suction (aspiration) ureteral access sheaths used during retrograde intrarenal surgery (RIRS) in adults with kidney stones.
- Trial name
- NCT07866209
- Testing
- Conventional Ureteral Access Sheath, Suction Ureteral Access Sheath
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Antalya Health Sciences University
Ureteral Calculi, Masturbation
Rate of Spontaneous Stone Passage as Assessed Using Urinary Ultrasonography and Direct Urinary System Radiography
To evaluate the effect of masturbation on the spontaneous expulsion of distal ureteral stones 5-10 mm in size.
- Trial name
- NCT04550559
- Testing
- Endoscopic ureterolitotripsy
- Where
- Turkey (Türkiye)
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Avrasya University
Neoplasm, Ureter, Neoplasm, Bladder
Prophylactic Intravesical Chemotherapy After Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: a Randomized Controlled Trial Between Single Postoperative Dose Versus Maintenance Therapy.
This clinical trial is designed to compare the effect of single postoperative intravesical chemotherapy instillation versus maintenance therapy on reducing bladder cancer recurrence after surgery for UTUC.
- Trial name
- NCT02438865
- Testing
- Immediate instillation of intravesical chemotherapy-Epirubicin-, Maintainance therapy of intravesical chemotherapy-Epirubicin-
- Where
- Egypt
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Ureteral Stent-Related Symptom
Ureteral Stent Related Lower Urinary Tract Symptoms- A Comparative Study
Pigtails are inserted to relieve of pelviureteral system independent of the underlying cause. Pain, Lower Urinary Tract Symptoms (LUTS), hematuria and fever can be some of the early complications after their insertion..More than…
- Trial name
- NCT05598710
- Testing
- Pigtail Insertion
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Ureter Stricture, Hydronephrosis
Post-Marketing Follow-Up of Long-term Type Ureteral Stent Set
Ureteral stents have been widely used in many urological operations. Although there are several reports regarding the effectiveness of long-term ureteral stents for malignancy ureteral obstruction, ureteral stricture and…
- Trial name
- NCT04250090
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- En Chu Kong Hospital
Ureteral Obstruction, Neoplasms
Antibiotic Prophylaxis in Percutaneous Nephrostomy Placements and Replacements for Malignant Urinary Tract Obstruction
This study aims to find out whether taking antibiotics to prevent a urinary tract infection after a medical procedure called percutaneous nephrostomy (placement of a catheter directly into the kidney to keep it working after the…
- Conditions
- Ureteral Obstruction, Neoplasms, Acute Kidney Injury, Nephrostomy; Complications
- Trial name
- NCT06801405
- Testing
- antibiotic prophylaxis
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- Barretos Cancer Hospital
Ureteric Calculus, Sepsis
Percutaneous Nephrostomy Versus Stent In Sepsis Trial
Randomized control trial to compare the efficacy and safety of percutaneous nephrostomy with retrograde ureteric stenting for emergency renal decompression in cases of obstruction and sepsis associated with ureteric calculi.
- Conditions
- Ureteric Calculus, Sepsis, Hydronephrosis
- Trial name
- PERSIST (NCT02929160)
- Testing
- Percutaneous nephrostomy, Retrograde ureteric JJ stent
- Where
- 2 sites in Ireland
- Sponsor
- The Adelaide and Meath Hospital, incorporating The National Children's Hospital
Ureteral Stent-Related Symptoms
Alfuzosin and Mirabegron for Double-J Stent Symptoms
This prospective randomized controlled trial investigates the effects of alfuzosin, mirabegron, and their combination on stent-related symptoms and outcomes in patients undergoing DJ stent placement after retrograde intrarenal…
- Trial name
- NCT07018934
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- University of Gaziantep
Pancreatic Cancer, Thyroid Cancer
Integrated Cancer Repository for Cancer Research
The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer…
- Conditions
- Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer
- Trial name
- iCaRe2 (NCT02012699)
- Where
- 42 sites in United States
- Volunteers
- 999,999 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Urolithiasis, Ureteral Injury
Effect of Preoperative Alpha-blockers on Successful Insertion Ureteral Access Sheath and Reduce Ureteral Injury in Non-prestented Patients During RIRS. Assessment of Factors for Successful Ureteral Access Sheath Insertion.
The aim of the study is to evaluate the effect of preoperative taking alpha-blockers (tamsulosin or silodosin) on the success rate of ureteral access sheath (UAS) insertion and the degree of ureteral injury during RIRS in…
- Conditions
- Urolithiasis, Ureteral Injury, Ureteral Access Sheath, Retrograde Intrarenal Surgery
- Trial name
- NCT07202923
- Where
- Russia
- Volunteers
- 140 people
- Sponsor
- St. Luke's Clinical Hospital, Russia
Urolithiasis
Multi-Center Comparison of Dual Lumen Versus Single Lumen Ureteroscopes
Urolithiasis (kidney stones) is a common disease process affecting people all across the world. Usually, if the stone size is small, it is able to pass through the urinary system and exit the bladder on its own with no treatment.
- Trial name
- NCT02123082
- Testing
- Storz single Lumen Ureteroscope, Dual Lumen Ureteroscope
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Urinary Stones, Urinary Tract Stones
Evaluation of Ureteral Stents in the Management of Stone Disease
A thin tube, called a ureteral stent, is inserted into the ureter and is commonly used as treatment of urinary stone disease. Stents are designed to help provide drainage of the kidney in the setting of an obstructing stone, or…
- Trial name
- NCT02211313
- Testing
- Randomization to size 6 French soft vs. size 6 French hydrophobic ureteral stent.
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Washington University School of Medicine
Adenocarcinoma, Adenocystic Carcinoma
The Registry of Oncology Outcomes Associated With Testing and Treatment
This study is to collect and validate regulatory-grade real-world data (RWD) in oncology using the novel, Master Observational Trial construct. This data can be then used in real-world evidence (RWE) generation.
- Conditions
- Adenocarcinoma, Adenocystic Carcinoma, Anal Cancer, Appendix Cancer
- Trial name
- ROOT (NCT04028479)
- Testing
- Biomarker Testing (L), Systemic Treatment (T), Patient Reported Outcomes (P)
- Where
- 2 sites in United States
- Volunteers
- 167 people
- Sponsor
- Taproot Health
Pelvi Ureteric Junction Obstruction or Ureteral Stricture
Buccal Mucosal Graft for the Repair of Iatrogenic Pelviureteric Junction Obstruction or Ureteric Stricture.
Prospective study to evaluate the safety and efficacy of using buccal mucosal graft for repairing complex cases of iatrogenic pelvi ureteric junction obstruction and long segment ureteric stricture disease.
- Trial name
- NCT04503330
- Testing
- buccal mucosal graft to repair iatrogenic PUJO
- Volunteers
- 20 people
- Sponsor
- Cairo University
Nephrolithiasis, Flexible Ureteroscopy
Bendable Suction Ureteral Access Sheath Versus Conventional Ureteral Access Sheath in Management of Renal Stones Using Flexible Ureteroscopy
Urinary calculus is a globally recognized urological condition, with prevalence rates ranging from 1% to 13% across different geographical regions (1) Therapeutic approaches for renal calculi encompass extracorporeal shock wave…
- Trial name
- NCT06862141
- Testing
- bendable suction ureteral access sheath, conventional suction ureteral access sheath
- Where
- Egypt
- Volunteers
- 172 people
- Sponsor
- Menoufia University
Hypertension, Uncontrolled Hypertension
A Study of Non-Vascular Renal Denervation Using the Verve Medical Phoenix ™ System
The aim of the study is to assess the safety and effectiveness of a novel device for renal denervation to lower blood pressure in people with uncontrolled hypertension.
- Trial name
- TUSK (NCT05440513)
- Testing
- Renal Pelvic Denervation (bilateral)
- Where
- 2 sites in Georgia
- Volunteers
- 20 people
- Sponsor
- Verve Medical, Inc
Ureterolithiasis, Renal Calculi
Super-Pulsed Thulium Fiber Laser Versus Holmium:YAG Laser in Retrograde Intrarenal Surgery for Upper Ureteral and Renal Stones
The holmium laser is currently considered the gold standard for lithotripsy on urinary lithiasis, whereas the super-pulsed thulium fibre laser is a relatively new technology.
- Trial name
- NCT07012941
- Testing
- Superpulse Thulium Fiber laser (SPTFL) ureteroscopy for treatment of upper urinary tract stone or renal stone, Holmium: YAG laser ureteroscopy for treatment of upper urinary tract stone or renal stone
- Where
- China
- Volunteers
- 448 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University