Clinical trials: Ureteral Diseases
Vesicoureteral Reflux
Prospective Pediatric Vesicoureteral Reflux Surgery Database
The purpose of this research is to provide a clearer understanding of quality and outcomes for three types of surgical procedures performed at Connecticut Children's for treatment of vesicoureteral reflux.
- Trial name
- NCT01373385
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Connecticut Children's Medical Center
Ureteric Stone
Ideal Time of Stenting Prior to Ureteral Access Sheath for Stone Disease
The miniaturization of endourological instruments and improvements in laser lithotripsy have revolutionized the approach to renal stones .
- Trial name
- NCT06761378
- Testing
- Renal stent, Flexible uretroscopy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Kidney Stone
Tip Bendable Suction Ureteral Access Sheath vs. Traditional Ureteral Access Sheath in Retrograde Intrarenal Stone Surgery
Nephrolithiasis is the most common chronic kidney condition and affecting approximately one in every 10-17 people in the world[1,2].
- Trial name
- NCT05952635
- Testing
- Tip bendable suction ureteral access sheath
- Where
- China
- Volunteers
- 320 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Stone, Kidney
Silodosin in Management of Lower Ureteral Stones
This research aims to study the effectiveness of silodosin in the management of lower ureter stones larger than 6 mm in diameter in terms of affected ureter (right or left), the size of the stone, the degree of hydronephrosis…
- Trial name
- NCT06381206
- Testing
- Silodosin
- Where
- Syria
- Volunteers
- 100 people
- Sponsor
- Syrian Private University
Advanced Bladder Urothelial Carcinoma, Advanced Ureter Urothelial Carcinoma
Atezolizumab and CYT107 in Treating Participants With Locally Advanced, Inoperable, or Metastatic Urothelial Carcinoma
This phase II trial studies how well atezolizumab when given with glycosylated recombinant human interleukin-7 (CYT107) works in treating patients with urothelial carcinoma that has spread to nearby tissue or lymph nodes (locally…
- Conditions
- Advanced Bladder Urothelial Carcinoma, Advanced Ureter Urothelial Carcinoma, Metastatic Bladder Urothelial Carcinoma, Metastatic Renal Pelvis Urothelial Carcinoma
- Trial name
- NCT03513952
- Testing
- Atezolizumab, Biopsy, Biospecimen Collection
- Where
- 9 sites in United States
- Volunteers
- 47 people
- Sponsor
- National Cancer Institute (NCI)
Hypertension, Uncontrolled Hypertension
A Study of Non-Vascular Renal Denervation Using the Verve Medical Phoenix ™ System
The aim of the study is to assess the safety and effectiveness of a novel device for renal denervation to lower blood pressure in people with uncontrolled hypertension.
- Trial name
- TUSK (NCT05440513)
- Testing
- Renal Pelvic Denervation (bilateral)
- Where
- 2 sites in Georgia
- Volunteers
- 20 people
- Sponsor
- Verve Medical, Inc
Kidney Stone, Ureter Obstruction
Is it Safe to Advance a Guidewire Through a Previously Placed Double j Stent?
In this prospective randomized controlled study, it is aimed to investigate the effects of guidewire advanced through a previously placed double j stent on postoperative complications, operation time and efficacy.
- Conditions
- Kidney Stone, Ureter Obstruction, Stent Complication
- Trial name
- NCT05265936
- Testing
- Passing a guidewire through a double j stent, Double J stent removal and guidewire insertion
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Ankara Training and Research Hospital
Urinary Tract Stone
Moses vs. Thulium Laser Study
The incidence of urinary tract stone disease is increasing. According to the National Health and Nutrition Examination Survey, as of 2012, 10.6% of men and 7.1% of women in the United States are affected by renal stone disease.
- Trial name
- NCT04963062
- Testing
- Holmium laser with Moses lasers, Holmium laser with thulium lasers
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- University of Wisconsin, Madison
Kidney Failure, Chronic, End Stage Renal Failure With Renal Transplant
Black Star - Magnetic Stent Removal in Transplant Patients
This is a pilot, single-centre, feasibility study to assess the feasibility issues and collect preliminary clinical data for the design of future randomized controlled trial to evaluate the feasibility and patient comfort of…
- Trial name
- NCT03143556
- Testing
- Magnetic stent
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Ureteral Obstruction
Drainage of Malignant Extrinsic Ureteral Obstruction Using the Memokath Ureteral Stent
The purpose of this study is to evaluate the safety and efficacy of the Memokath 051 ureteral stent as a long-term temporary and minimally invasive means of providing ureteral drainage in the setting of malignant extrinsic…
- Trial name
- NCT00166361
- Testing
- Memokath 051 Ureteral Stent, JJ Stent
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Mayo Clinic
Ureteral Obstruction
Comparison of Dynamic Contrast Enhanced CT and Diuretic Renogram in The Evaluation of UPJO
Renal blood flow is inversely related to obstruction. We propose that this imaging will be as effective as the diuretic renogram in the functional diagnosis of obstruction.
- Trial name
- NCT00199472
- Testing
- Dynamic Contrast Enhanced CT & Diuretic Renogram
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Ureterolithiasis, Ureteral Calculi
Evaluation of Tamsulosin in the Treatment of Ureteral Stones
Ureteral stones have an important place in daily urological practice, usually causing acute episodes of ureteral colic by obstructing the urinary tract.
- Trial name
- TAMSULOSINE (NCT00151567)
- Testing
- Tamsulosin
- Where
- 6 sites in France
- Volunteers
- 129 people
- Sponsor
- Rennes University Hospital
Locally Advanced Bladder Urothelial Carcinoma, Locally Advanced Renal Pelvis Urothelial Carcinoma
ARID1A and/or KDM6A Mutation and CXCL13 Expression
This phase II trial studies the effect of nivolumab in urothelial cancer that has spread to other places in the body (metastatic), specifically in patients with aberrations in ARID1A gene (ARID1A mutation) and correlate with…
- Conditions
- Locally Advanced Bladder Urothelial Carcinoma, Locally Advanced Renal Pelvis Urothelial Carcinoma, Locally Advanced Ureter Urothelial Carcinoma, Locally Advanced Urethral Urothelial Carcinoma
- Trial name
- NCT04953104
- Testing
- Diagnostic Laboratory Biomarker Analysis, Nivolumab, Relatlimab
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- M.D. Anderson Cancer Center
Stones, Kidney, Ureter Stones
A Comparative Study Between the Usage of Flexible and Navigable Suction Ureteral Access Sheath Versus Traditional Access Sheath in Retrograde Intrarenal Surgeries
A comparative study between the Usage of Flexible and Navigable Suction Ureteral Access Sheath (FANS) versus Traditional Access sheath in RIRS : Randomized controlled trial .
- Trial name
- NCT07076589
- Testing
- FURS
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Yosseif elhousseiny ammar ahmed
Kidney Calculi
Quality of Life in Patients With Double Loop Ureteral Stent (JJ Silicone Hydrogel Study)
This study is a prospective, randomized multicenter study conducted in Europe. It is designed to compare two double loop ureteral stents in terms of the quality of life in patients operated on a kidney stone and requiring the…
- Trial name
- NCT02489656
- Testing
- Double Loop Ureteral stent endoscopic placement.
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Coloplast A/S
Urolithiasis, Tamsulosin
Medication Facilitated Ureteral Access Sheath Deployment During Ureteroscopy: The Impact of One Week of Preoperative Tamsulosin
The goal of this clinical trial is to assess whether tamsulosin given one week prior to renal or ureteric stone surgery would improve the success rate of ureteral access sheath deployment and decrease ureteral injury
- Conditions
- Urolithiasis, Tamsulosin, Pre-operative, Ureteral Access Sheath Placement
- Trial name
- NCT07847866
- Testing
- Tamsulosin 0.4 MG, Control
- Where
- 2 sites in Singapore
- Volunteers
- 111 people
- Sponsor
- Singapore General Hospital
Urothelial Carcinoma, Bladder Cancer
Phase I Study With Sorafenib in Addition to Vinflunine in Metastatic Transitional Cell Carcinoma of the Urothelial Tract
This study aims to analyse the tolerability (side effects and safety) with standard treatment (Javlor®) with the addition of a second anti-tumour drug: sorafenib (Nexavar®).
- Conditions
- Urothelial Carcinoma, Bladder Cancer, Renal Pelvis Cancer, Ureter Cancer
- Trial name
- VINSOR (NCT01844947)
- Testing
- Vinflunine, Sorafenib
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 22 people
- Sponsor
- Dr Anders Ullén
Indications for Laparoscopic Thoracic and Abdominal Surgery in Children, Congenital or Acquired Surgical Conditions Requiring Minimally Invasive Surgery in Children
Clinical Trial on Safety and Efficacy of Thoracoabdominal Endoscopic Surgical System for Pediatric Surgery
This is a prospective, multi-center, single-arm, target-value clinical trial conducted to evaluate the safety and effectiveness of the Thoracic and Abdominal Endoscopic Surgery System (model WJ-SR01-200) in pediatric surgical…
- Conditions
- Indications for Laparoscopic Thoracic and Abdominal Surgery in Children, Congenital or Acquired Surgical Conditions Requiring Minimally Invasive Surgery in Children, Pyeloplasty, Ureteral Reimplantation
- Trial name
- NCT07530133
- Testing
- Thoracic and Abdominal Endoscopic Surgery System
- Where
- 3 sites in China
- Volunteers
- 64 people
- Sponsor
- Hangzhou Kangji Weijing Medical Robotics Co., Ltd.
Renal Stone, Kidney; Complications
Evaluation of Renal Oxygenation by NIRS in Pediatric Endourologic Stone Surgery
The study aims to compare renal oxygenation levels in retrograde intrarenal surgery (RIRS) and ureteroscopy (URS) procedures with a control group.
- Conditions
- Renal Stone, Kidney; Complications, Ureter Stone, Renal Oxygenation
- Trial name
- NCT06110247
- Testing
- NIRS, Taking a blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- Ankara City Hospital Bilkent
Urolithiasis, Ureterolithiasis
PRedictive Accuracy of Initial Stone Burden Evaluation.
This study is intended to be a prospective registry of patients undergoing any kind of stone treatment that have a pre-operative CT available.
- Conditions
- Urolithiasis, Ureterolithiasis, Nephrolithiasis
- Trial name
- PRAISE (NCT04746378)
- Testing
- Computed Tomography, CSD, Computed Tomography, SA, Computed Tomography, 3D
- Where
- Belgium
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Ghent