Clinical trials: Ureteric Injury
Intraoperative Ureter Injury
Dose-escalation Study of a Contrast Agent for Delineation of Urological Anatomy in Minimally Invasive Surgery
The purpose of this clinical trial is to study the safety and efficacy of an investigational imaging agent for delineation/visualization of urologic anatomy in the setting of minimally invasive surgery.
- Trial name
- NCT03106038
- Testing
- Nerindocianine for Injection
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Li-Cor, Inc.
Ureter Injury
3,3'-Dioxo-2,2'-Bisindolylidene-5,5'-Disulfonate Disodium 0.8% Solution as an Aid for Ureteral Patency
To determine whether the use of 3,3'-Dioxo-2,2'-Bisindolylidene-5,5'-Disulfonate Disodium 0.8% Solution for injection provides a visualization advantage compared to saline when used as an aid in the determination of ureteral…
- Trial name
- UP (NCT04228445)
- Testing
- 3,3'-Dioxo-2,2'-bisindolylidene-5,5'-disulfonate disodium 0.8%, Saline spray
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Prove pharm
Ureter Injury
A Safety and Feasibility Study of IS-001 Injection in Patients Undergoing Robotic Colorectal Surgery
This study evaluates the safety and feasibility of intravenous injection of IS-001 to aid in intraoperative ureter structure delineation
- Trial name
- NCT05769257
- Testing
- IS-001
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Intuitive Surgical
Kidney Stone, Retrograde Intrarenal Surgery (RIRS)
MIRABEGRON AND UAS OUTCOMES DURING RIRS
The aim of this study is to evaluate whether there is a difference in the passage rate of the ureteral access sheath between patients who used mirabegron (a beta-3 receptor agonist) for overactive bladder and those who underwent…
- Conditions
- Kidney Stone, Retrograde Intrarenal Surgery (RIRS), Ureteral Access Sheath
- Trial name
- NCT07566416
- Testing
- Retrograde intrarenal surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 131 people
- Sponsor
- Ankara Training and Research Hospital
Children, Obstructive Uropathy
Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage
To compare percutaneous nephrostomy (PCN) versus double J stent (JJ) as an initial urinary drainage in children
- Conditions
- Children, Obstructive Uropathy, Acute Renal Failure, Ureteric Stones
- Trial name
- NCT02055430
- Testing
- percutaneous nephrostomy insertion, bilateral double J ureteric stent, Definitive stone management
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Bladder Injury, Ureter Injury
Comparison of Standard Cystoscopy With Carbon Dioxide Cystoscopy
For the evaluation of the lower urinary tract after laparoscopic hysterectomy, routine standard saline cystoscopy and carbon dioxide cystoscopy will be compared.
- Conditions
- Bladder Injury, Ureter Injury, Surgical Injury, Complication of Surgical Procedure
- Trial name
- NCT06278753
- Testing
- carbon dioxide cystoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 540 people
- Sponsor
- Tepecik Training and Research Hospital
Open, Laparoscopic
Open Versus Laparoscopic Dismembered Pyeloplasty Among Adult Patients With Primary Pelvi-Ureteric Junction Obstruction
To prospectively compare the perioperative, morphological and functional outcomes on short and medium term between laparoscopic (LP) and open pyeloplasty (OP) patients.
- Conditions
- Open, Laparoscopic, Dismembered Pyeloplasty, Primary Pelvi-Ureteric Junction
- Trial name
- NCT06572371
- Testing
- Laparoscopic pyeloplasty, Open pyeloplasty
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Tanta University
Ureteral Injury
Investigating Oral Agents for Urine Staining to Facilitate Intraoperative Observation of Ureteral Jets
Recently, Indigo Carmine and Methylene Blue have been the standard agents to visualize ureteral jets during intraoperative cystoscopy.
- Trial name
- NCT03432572
- Testing
- Pyridium, Riboflavin, Thiamine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Ureteral Injury
Evaluation of Sodium Fluorescein Use During Intraoperative Cystoscopy After Total Laparoscopic Hysterectomy
The primary objective is to describe the safety and efficacy of intravenous sodium fluorescein to visualize ureteral efflux during intraoperative cystoscopy after total laparoscopic hysterectomy.
- Trial name
- NCT02971800
- Testing
- sodium fluorescein injection 10%
- Where
- Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Intraoperative Ureter Visualization, Abdominolpelvic Surgery
A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery in People With or Without Kidney Disease
The ureter is the tube that carries urine from the kidneys to the bladder. It is difficult for surgeons to see the ureter during abdominal surgery. This could lead to injuring the ureter which, although rare, could be serious.
- Trial name
- NCT05999747
- Testing
- pudexacianinium chloride
- Where
- 12 sites in United States
- Volunteers
- 95 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Colorectal Cancer, Colorectal Surgery
Assessing the Feasibility of Using Methylene Blue in Identifying Ureters During Colorectal Surgery
This study will assess whether methylene blue fluorescence imaging can help surgeons identify the ureters during colorectal surgery.
- Conditions
- Colorectal Cancer, Colorectal Surgery, Ureteric Injury
- Trial name
- NCT07861815
- Testing
- Intravenous Methylene Blue, Methylene Blue Fluorescence Imaging System
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Urinary Tract Infections, Ureteric Injury
Safety and Efficacy of Different Irrigation System in Retrograde Intrarenal Surgery
Urolithiasis is one of the most prevalent urological diseases affecting general population across the world. The available treatment modalities for renal stones are Shock wave lithotripsy (SWL), Percutaneous Nephrolithotomy…
- Conditions
- Urinary Tract Infections, Ureteric Injury, Sepsis
- Trial name
- RIRS (NCT05018546)
- Testing
- Irrigation force
- Where
- Nepal
- Volunteers
- 92 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Ureteral Injury, Surgery--Complications
Ureteral Jets and Patient Positioning Study
The objective of the study is to identify the relationship between patient position during surgery and time to confirmation of ureteral patency on cystoscopy.
- Trial name
- NCT04732403
- Testing
- Patient Position
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Spinal Cord Injuries
Ureteric Jet Doppler Waveforms in Patients With Spinal Cord Injury
Urinary dysfunction is very common in individuals with spinal cord injury. The urine flowing from the collecting ducts to the renal calyx stretches the calyces.
- Trial name
- NCT05568862
- Testing
- Doppler ultrasound, Urodynamic assessment., Urodynamic assessment.
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Ureter Injury
Indigotindisulfonate Sodium Injection, USP as an Aid in the Determination of Ureteral Patency in Pediatric Patients
This is an open-label, multicenter study to evaluate the safety, pharmacokinetics, and conspicuity of a weight-based Bludigo® dose (0.05 mL/kg rounded up (if necessary) to a minimum of 0.5 mL and not to exceed 2.5 mL) when used…
- Trial name
- NCT06448143
- Testing
- Indigotindisulfonate sodium 0.8% injection
- Volunteers
- 18 people
- Sponsor
- Prove pharm
Renal Injury, Kidney Injury
Efficacy and Safety of Renalof® in the Removal of Calculi Smaller Than 10 mm Located in the Reno-Ureteral Tract
Given the high recurrence of urolithiasis in patients, the search for less aggressive and preventive treatments is increasingly necessary.
- Conditions
- Renal Injury, Kidney Injury, Kidney Calculi, Ureteral Obstruction
- Trial name
- NCT04695951
- Testing
- Renalof
- Where
- Nicaragua
- Volunteers
- 155 people
- Sponsor
- Catalysis SL
Nephrolithiasis
Tissue Sensor for Semirigid Thulium Fiber Laser Ureterolithotripsy
Tissue Sensor (TS) is a technology designed to automatically deactivate laser emission when contact between the laser fiber and tissue is detected.
- Trial name
- Tissue Sensor (NCT07835113)
- Testing
- Semirigid TFL ureterolithotripsy with Tissue Sensor activated., Semirigid TFL ureterolithotripsy with Tissue Sensor deactivated.
- Volunteers
- 121 people
- Sponsor
- Botkin Hospital
Injury of Ureter
Evaluation of Ureteral Jets on Cystoscopy
This study evaluates 4 different methods to aid surgeons to visualize ureteral jets on cystoscopy.
- Trial name
- JET (NCT02476448)
- Testing
- Normal saline, Phenazopyridine, Dextrose 10%
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Cecilia Calvo
Intraoperative Ureter Visualization, Abdominolpelvic Surgery
A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery
The ureter was the tube that carries urine from the kidneys to the bladder. It was difficult for surgeons to see the ureter during abdominal surgery. This could lead to injuring the ureter which, although rare, could be serious.
- Trial name
- NCT05754333
- Testing
- pudexacianinium chloride
- Where
- 6 sites in United States
- Volunteers
- 107 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Uterovaginal Prolapse, Ureteral Injury
Ureteral Patency After Uterosacral Ligaments Suspension
Uterosacral ligament suspension (USLS) is a commonly performed procedure used to correct prolapse of the vaginal apex. The procedure consists of approximating the vaginal apex to the uterosacral ligaments with a series of sutures…
- Conditions
- Uterovaginal Prolapse, Ureteral Injury, Surgery--Complications
- Trial name
- NCT05477043
- Testing
- Transabdominal ultrasound and cistoscopy
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca