Clinical trials: Ureteric Injury
Intraoperative Ureter Injury
Dose-escalation Study of a Contrast Agent for Delineation of Urological Anatomy in Minimally Invasive Surgery
The purpose of this clinical trial is to study the safety and efficacy of an investigational imaging agent for delineation/visualization of urologic anatomy in the setting of minimally invasive surgery.
- Trial name
- NCT03106038
- Testing
- Nerindocianine for Injection
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Li-Cor, Inc.
Ureter Injury
3,3'-Dioxo-2,2'-Bisindolylidene-5,5'-Disulfonate Disodium 0.8% Solution as an Aid for Ureteral Patency
To determine whether the use of 3,3'-Dioxo-2,2'-Bisindolylidene-5,5'-Disulfonate Disodium 0.8% Solution for injection provides a visualization advantage compared to saline when used as an aid in the determination of ureteral…
- Trial name
- UP (NCT04228445)
- Testing
- 3,3'-Dioxo-2,2'-bisindolylidene-5,5'-disulfonate disodium 0.8%, Saline spray
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Prove pharm
Ureter Injury
A Safety and Feasibility Study of IS-001 Injection in Patients Undergoing Robotic Colorectal Surgery
This study evaluates the safety and feasibility of intravenous injection of IS-001 to aid in intraoperative ureter structure delineation
- Trial name
- NCT05769257
- Testing
- IS-001
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Intuitive Surgical
Intraoperative Ureter Visualization, Abdominolpelvic Surgery
A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery in People With or Without Kidney Disease
The ureter is the tube that carries urine from the kidneys to the bladder. It is difficult for surgeons to see the ureter during abdominal surgery. This could lead to injuring the ureter which, although rare, could be serious.
- Trial name
- NCT05999747
- Testing
- pudexacianinium chloride
- Where
- 12 sites in United States
- Volunteers
- 95 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Ureter Injury
Indigotindisulfonate Sodium Injection, USP as an Aid in the Determination of Ureteral Patency in Pediatric Patients
This is an open-label, multicenter study to evaluate the safety, pharmacokinetics, and conspicuity of a weight-based Bludigo® dose (0.05 mL/kg rounded up (if necessary) to a minimum of 0.5 mL and not to exceed 2.5 mL) when used…
- Trial name
- NCT06448143
- Testing
- Indigotindisulfonate sodium 0.8% injection
- Volunteers
- 18 people
- Sponsor
- Prove pharm
Renal Injury, Kidney Injury
Efficacy and Safety of Renalof® in the Removal of Calculi Smaller Than 10 mm Located in the Reno-Ureteral Tract
Given the high recurrence of urolithiasis in patients, the search for less aggressive and preventive treatments is increasingly necessary.
- Conditions
- Renal Injury, Kidney Injury, Kidney Calculi, Ureteral Obstruction
- Trial name
- NCT04695951
- Testing
- Renalof
- Where
- Nicaragua
- Volunteers
- 155 people
- Sponsor
- Catalysis SL
Intraoperative Ureter Visualization, Abdominolpelvic Surgery
A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery
The ureter was the tube that carries urine from the kidneys to the bladder. It was difficult for surgeons to see the ureter during abdominal surgery. This could lead to injuring the ureter which, although rare, could be serious.
- Trial name
- NCT05754333
- Testing
- pudexacianinium chloride
- Where
- 6 sites in United States
- Volunteers
- 107 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Ureter Injury
Indigotindisulfonate Sodium as an Aid in Determination of Ureteral Patency in Patient's With Renal Impairment
This is an open label, randomized, multicenter study to evaluate the efficacy and safety of two dose levels (2.5 mL and 5.0 mL) of Indigotindisulfonate Sodium Injection, USP 0.8% when used as an aid in the determination of…
- Trial name
- NCT06085183
- Testing
- Saline Injection 0.9%, Indigotindisulfonate sodium 0.8%
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Prove pharm
Ureter Injury
Evaluation of Lumitrace for Visualizing Ureters During Abdominopelvic Surgeries
The goal of this clinical trial is to learn if Lumitrace and the KARL STORZ POWER LED BLUE System can be used for anatomic visualization of the ureters in participants undergoing laparoscopic abdominopelvic surgery.
- Trial name
- NCT07080008
- Testing
- Lumitrace, KARL STORZ POWER LED BLUE System
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- MediBeacon
Ureter Injury
IS-001 Injection in Patients Undergoing Robotic-Assisted Colorectal Surgery
This study evaluates the safety and efficacy of intravenous injection of IS-001 to aid in intraoperative ureter structure delineation
- Trial name
- NCT07346066
- Testing
- filricianine
- Where
- 9 sites in United States
- Volunteers
- 146 people
- Sponsor
- Intuitive Surgical
Ureter Injury
A Safety and Efficacy Study of IS-001 Injection in Patients Undergoing Robotic Hysterectomy
This study evaluates the safety and efficacy of intravenous injection of IS-001 to aid in intraoperative ureter structure delineation.
- Trial name
- NCT03937505
- Testing
- IS-001, No treatment
- Where
- 3 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Intuitive Surgical
Ureter Injury
Indigotindisulfonate Sodium Injection, USP as an Aid in the Determination of Ureteral Patency
This is a randomized, multicenter study to evaluate the efficacy and safety of two dose levels (2.5 mL and 5.0 mL) of Bludigo when used as an aid in the determination of ureteral patency.
- Trial name
- NCT06054880
- Testing
- Indigotindisulfonate sodium 0.8%, Saline injection 0.9%
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Prove pharm
Surgery, Nerve Injury
A Study of Bevonescein in Patients Undergoing Abdominopelvic Surgery
Feasibility study of Bevonescein to highlight Nerves and Ureter in patients undergoing Minimally Invasive Surgery
- Conditions
- Surgery, Nerve Injury, Imaging
- Trial name
- NCT06662097
- Testing
- Bevonescein
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alume Biosciences, Inc.
Ureter Injury
IS-001 Injection in Patients Undergoing Robotic-Assisted Gynecological Surgery
This study evaluates the safety and efficacy of intravenous injection of IS-001 to aid in intraoperative ureter structure delineation.
- Trial name
- NCT05954767
- Testing
- IS-001
- Where
- 8 sites in United States
- Volunteers
- 189 people
- Sponsor
- Intuitive Surgical
Intraoperative Ureter Injury
Open-label Study to Evaluate Nerindocianine as a Surgical Aid in Ureter Delineation During Minimally Invasive Surgery
Phase 2, multicenter, efficacy and safety study evaluating the use of nerindocianine for the delineation of abdominopelvic ureter anatomy via near infrared fluorescence imaging during minimally invasive lower abdominal surgery…
- Trial name
- NCT04636567
- Testing
- Nerindocianine for injection
- Where
- 2 sites in United States
- Sponsor
- Li-Cor, Inc.
Injury of Ureter During Surgery (Disorder)
Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery
The goal of this clinical trial is to determine if the drug Nizaracianine Triflutate can help surgeons see and avoid the ureters during abdominopelvic surgery.
- Trial name
- TRIPHASE (NCT06101745)
- Testing
- Nizaracianine Triflutate
- Where
- 10 sites in United States, Netherlands
- Volunteers
- 336 people
- Sponsor
- Curadel Surgical Innovations, Inc.