Clinical trials: Ureteroscopy
Renal Stone, Ureteral Stone
Better Lithotripsy and Ureteroscopy Evaluation of Stenting (BLUES)
This multi-center trial is being completed to compare patient outcomes related to the Imajin silicone stent in comparison to non-silicone polyurethane stents after ureteroscopy.
- Trial name
- BLUES (NCT05026710)
- Testing
- Silicone (Coloplast Imajin Hydro) ureteral stent, Non-silicone (Polyurethane/Percuflex) ureteral stent (any manufacturer)
- Where
- 10 sites in United States
- Volunteers
- 224 people
- Sponsor
- University of Michigan
Infections, Urinary Tract, Nephrolithiasis
Preoperative Prophylactic Antibiotic Duration in Moderate to High Risk Ureteroscopy
The goal of this non-inferiority randomized controlled trial: is to test the hypothesis that the that there is no additional benefit from a longer course (7 days) versus a shorter course (2 days) of pre-operative antibiotics in…
- Trial name
- NCT06149455
- Testing
- Duration of antibiotics
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Kidney Stone
LithoVue Single Use Disposable Ureteroscope
Most flexible ureteroscopes that are used to treat kidney stones have been reusable. Recently, advances in technology have resulted in single-use (disposable) ureteroscopes to become available.
- Trial name
- NCT03419091
- Testing
- single-use flexible digital ureteroscope, Reusable Ureteroscope
- Where
- 2 sites in United States, Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Kidney Stone, Ureteral Stone
Access Sheath and Stent Trial
The study is being completed to compare patient reported outcomes for stent omission vs. placement after using a ureteral access sheath for uncomplicated ureteroscopy.
- Trial name
- ACCENT (NCT07297953)
- Testing
- Surveys
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- University of Michigan
Nephrolithiasis
Massage Percussion for Passage of Urolithiasis Fragments After Ureteroscopy.
Flexible ureteroscopy is characterized as first-line therapy for renal stones < 2 cm in size. Stones are commonly treated with dusting or fragmentation techniques which requires passage of stone fragments after surgery.
- Trial name
- NCT05872230
- Testing
- Massage Percussion Therapy device
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Flexible Ureteroscopy
Preoperative Prediction of Flexible Ureteroscopy Outcome in the Treatment of Renal Calculi
To predict the outcome of flexible ureteroscopy in the management of renal stones based on preoperative scoring module using five preoperative parameters that have effect on stone free status postoperatively.
- Trial name
- NCT05857501
- Testing
- abdominopelvic computerized tomography (CT) without contrast
- Volunteers
- 72 people
- Sponsor
- Menoufia University
Flexible Ureteroscopy
Ureteral Access Sheath or Percutaneous Nephrostomy During Flexible Ureteroscopy: Which is Better?
we aim to compare the safety and efficacy of flexible ureteroscopy with ureteral access sheath (group A) in comparison with flexible ureteroscopy without UAS but with PCN insertion (group B) either intra or post operaively by…
- Trial name
- NCT05633030
- Testing
- using UAS during flexible ureteroscopy and using PCN during flexible ureteroscopy
- Volunteers
- 100 people
- Sponsor
- Benha University
Urolithiasis, Calyx; Calculus
Citrate Salts for Stone-free Result After Flexible Ureterorenoscopy for Inferior Calyx Calculi
The prevalence of urolithiasis is around 10 % in the French population. It is thus a major public health issue. When the stone is not spontaneously removed, interventions such as extracorporeal lithotripsy or flexible…
- Trial name
- CiRUS (NCT04021381)
- Testing
- Potassium and magnesium citrate
- Where
- France
- Volunteers
- 262 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pediatric Renal Stones
Efficacy and Safety of Flexible Ureteroscopy With Flexible Navigable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheath
Mini-percutaneous nephrolithotomy (mini-PCNL) and retrograde intrarenal surgery (RIRS) are both effective treatment modalities for renal calculi measuring up to 2.5 cm in pediatric patients, demonstrating similar efficacy and…
- Trial name
- NCT07763743
- Testing
- Flexible Ureteroscopy
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Ureteric Stones
Treatment of Upper Ureteric Stones
This study will be conducted to compare the success and complication rates of ureteroscopy, and shockwaves lithotripsy for treatment of upper ureteric stones ≤1 cm.
- Trial name
- NCT02469766
- Testing
- SWL, Semirigid URS, Flexible URS
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Mansoura University
Renal Calculi (Kidney Stones) ≤ 20 mm
Super-Mini Percutaneous Nephrolithotomy Versus Flexible Ureteroscopy for Renal Stones 20 mm or Less
Kidney stones measuring 20 mm or less are commonly managed using minimally invasive surgical techniques. Two widely used approaches are Super-mini Percutaneous Nephrolithotomy (SMP) and Flexible Ureteroscopy (fURS).
- Trial name
- NCT07371494
- Testing
- Super-mini Percutaneous Nephrolithotomy, Flexible Ureteroscopy
- Where
- Vietnam
- Volunteers
- 72 people
- Sponsor
- Hanoi Medical University
Urolithiasis, Stones, Kidney
Trial of Ureteroscopy vs Steerable Continuous Flow Aspiration Technology
The goal of this clinical trial is to compare Steerable Ureteroscopic Renal Evacuation (SURE) using the CVAC System and standard ureteroscopy (URS) with laser lithotripsy for the treatment of urolithiasis.
- Conditions
- Urolithiasis, Stones, Kidney, Renal Stones, Kidney Stones
- Trial name
- TRUST (NCT07101809)
- Testing
- Steerable Ureteroscopic Renal Evacuation (SURE) using the CVAC System, Standard Ureteroscopy (URS)
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Calyxo, Inc.
Urolithiasis
Renal Stone Treatment Global Registry
This is an international prospective data registry to assess the treatment outcomes and complications of different treatment approaches for different surgical treatment of urolithiasis.
- Trial name
- NCT05297331
- Where
- 3 sites in Hong Kong
- Volunteers
- 3,000 people
- Sponsor
- Chinese University of Hong Kong
Anesthesia, Urethral Obstruction
Gabapentin on Postoperative Pain Associated With Ureteroscopy and Stents Insertion
The study's objective is to determine the efficacy of preoperative gabapentin in relieving postoperative pain, reducing opioid use and improving quality of recovery in subjects undergoing urologic surgery.
- Trial name
- NCT03151746
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Northwestern University
Kidney Stone, Ureteral Stone
Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Moses On or Moses Off
The purpose of this study is to compare Moses 2.0 pulse modulation technology and the standard high powered Holmium Laser lithotripsy and how it will affect time in the operating room, time using the laser, laser energy, and…
- Trial name
- NCT06346483
- Testing
- Dusting without Moses 2.0 Modulation, Dusting with Moses 2.0 Modulation, Moses 2.0 Modulation
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Northwestern University
Kidney Calculi, Nephrolithiasis
Comparison of Suction and Conventional Ureteral Access Sheaths in Kidney Stone Surgery
The goal of this observational study is to compare conventional and suction (aspiration) ureteral access sheaths used during retrograde intrarenal surgery (RIRS) in adults with kidney stones.
- Trial name
- NCT07866209
- Testing
- Conventional Ureteral Access Sheath, Suction Ureteral Access Sheath
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Antalya Health Sciences University
Urolithiasis, Kidney Stone
Flexible Ureteroscopy With Tip-bendable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for Treatment of 2-3cm Renal Stones
Background: Percutaneous nephrolithotomy (PCNL) is the first-line treatment for renal stones larger than 2 cm according to EAU and AUA guidelines.
- Trial name
- NCT06526390
- Testing
- f-URS, mini-PCNL
- Where
- China
- Volunteers
- 720 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Calculi
Initial Clinical Experience With the MONARCH Platform, Urology for the Treatment of Kidney Stones
The purpose of this study is to collect descriptive performance data using the MONARCH Platform, Urology (a novel robotic device) to perform mini-percutaneous nephrolithotomy (kidney stone removal) procedures.
- Trial name
- NCT05835323
- Testing
- Robotic-assisted mini-PCNL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Auris Health, Inc.
Kidney Stone
Thulium Fiber Laser Prospective Trial
This is a multi-center, prospective clinical trial to assess the effect of TFL for the lithotripsy of kidney stones.
- Trial name
- TFL (NCT05814133)
- Testing
- Thulium Fiber Laser
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Renal Stone, Pediatric
Flexible Ureteroscopy Versus Mini- Percutaneous Nephrolithotomy in Management of Pediatric Renal Stones Less Than 2 cm
This single-center, prospective, two-arm randomized controlled trial included 58 patients younger than 18 years who were allocated 1:1 to Mini-PCNL or FURS between June 2023 and December 2024.
- Trial name
- NCT07870200
- Testing
- Group A :Flexible ureteroscope group, Group B : Mini perc group
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Elsayed Abdelhalim Elsayed