Clinical trials: Urge Urinary Incontinence
Urge Incontinence, Overactive Bladder
Red Clover Isoflavones in Postmenopausal Women With Urge Urinary Incontinence and Overactive Bladder
The purpose of this study is to investigate the effect of red clover isoflavones in postmenopausal women with and without urge urinary incontinence and overactive bladder
- Trial name
- NCT05013593
- Testing
- Red Clover Extract (RCE)
- Where
- Denmark
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Regionshospital Nordjylland
Overactive Bladder
The Estrogen Impact on Overactive Bladder Syndrome: Female Pelvic Floor Microbiomes and Antimicrobial Peptides
The medical field is beginning to adopt treatments that alter an individual's microbiome to improve patient health; however, this approach has not been adopted for treatment of lower urinary tract symptoms (LUTS).
- Trial name
- NCT02524769
- Testing
- conjugated estrogen
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Loyola University
Urinary Incontinence, Urge
Refractory Overactive Bladder: Sacral NEuromodulation v. BoTulinum Toxin Assessment (ROSETTA)
The purpose of this randomized, open-label, active-control trial is to compare the effectiveness of intra-detrusor botulinum toxin A (Botox A®, Allergan) versus sacral neuromodulation (InterStim®, Medtronic) for the treatment of…
- Trial name
- ROSETTA (NCT01502956)
- Testing
- InterStim® device, Botox® injection
- Where
- 9 sites in United States
- Volunteers
- 386 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Urinary Incontinence, Urge
Cycling Versus Continuous Mode in Neuromodulator Programming
The investigators objective is to compare patient outcomes as changes in validated symptom measures of overactive bladder, the Overactive Bladder Questionnaire Short Form (OABq-SF) symptom scale, between women who are set on…
- Trial name
- NCT02551822
- Testing
- sacral neuromodulator
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- University of New Mexico
Incontinence, Urinary and Urinary Bladder, Overactive, Overactive Bladder
Effects Of GW679769 On Bladder Nerve Function And Symptoms Of Overactive Bladder In Spinal Cord Injury Patients
This is a two-part study in which Part A will assess the effects of GW679769 after 1 dose on the function of the nerves that supply the bladder. The technique for measuring the nerves function is called Neurometry.
- Trial name
- NCT00332319
- Testing
- GW679769
- Where
- 3 sites in United States
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Urge Incontinence
Protect Chronic Tibial Nerve Stimulator (CTNS) System
30 patient Study. All patients implanted with StimGuard Protect System. Patient followed out to 90 days.
- Trial name
- NCT02781636
- Testing
- Device: StimGuard Protect System
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Uro Medical Corporation
Fecal Incontinence, Accidental Bowel Leakage
Effects of Eluxadoline (Viberzi®) 100 mg Twice Daily on Diarrhea-Associated Fecal Incontinence
Accidental bowel leakage (fecal incontinence) increases in people who have diarrhea and sensations of urgency to have a bowel movement.
- Conditions
- Fecal Incontinence, Accidental Bowel Leakage, Anal Incontinence, Diarrhea
- Trial name
- ELXDFI (NCT03489265)
- Testing
- Eluxadoline 100 mg
- Sponsor
- University of North Carolina, Chapel Hill
Urinary Incontinence
A Practice-Based Intervention To Improve Care for a Diverse Population Of Women With Urinary Incontinence
The main goal of this clinical trial is to improve the care for urinary incontinence (UI) provided to adult women by primary care providers.
- Trial name
- OPTIMA (NCT05534412)
- Testing
- Academic Detailing, Electronic Clinical Decision Support, APP Co-management
- Where
- 4 sites in United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Overactive Bladder
Behavioral Modification and Vesicare Versus Vesicare Alone for Urge Incontinence in Patients With Overactive Bladder
This study will help determine if behavior modification performed in conjunction with oral Vesicare anticholinergic therapy is more effective for treating overactive bladder symptoms than oral Vesicare anticholinergic therapy…
- Trial name
- NCT00821184
- Testing
- Vesicare (solifenacin), Vesicare (solifenacin) plus behavioral modification
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Lahey Clinic
Urinary Incontinence,Stress, Urinary Incontinence, Urge
Effect of Mobile Application on Urinary Incontinence
The first phase was designed in a methodological pattern in order to develop, usability, and performance of mobile application (mobileapp) called "My Fight with Incontinence".
- Conditions
- Urinary Incontinence,Stress, Urinary Incontinence, Urge, Urinary Incontinence, Mixed, Symptoms
- Trial name
- NCT05404386
- Testing
- Training booklet prepared by the researchers on healthy lifestyle behaviors, bladder training, and Kegel exercises related to urinary incontinence., 3 months follow-up, Mobile application which named as "My Fighting with Incontinence"
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Eskisehir Osmangazi University
Urinary Incontinence, Detrusor Overactivity
Refractory Urge Incontinence and Botox Injections
The purpose of this study is to see whether Botox A (injected into the bladder muscle) can improve symptoms of urge incontinence that has not improved with usual medical treatments.
- Conditions
- Urinary Incontinence, Detrusor Overactivity, Urinary Urgency, Urge Urinary Incontinence
- Trial name
- NCT00373789
- Testing
- Botulinum Toxin A, bladder detrusor muscle injection
- Where
- 8 sites in United States
- Volunteers
- 87 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Overactive Bladder Syndrome, Urinary Urge Incontinence
Platelet-Rich Plasma Versus Botulinum Toxin for Refractory Overactive Bladder: A Randomized Trial
Overactive bladder is a common condition that causes sudden urges to urinate, frequent urination, night-time urination, and sometimes leakage of urine.
- Conditions
- Overactive Bladder Syndrome, Urinary Urge Incontinence, Detrusor Overactivity
- Trial name
- NCT07184307
- Testing
- Platelet-Rich Plasma, Intravesical Botulinum Toxin Injection
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Benha University
Urinary Incontinence
Study to Evaluate the Safety and Efficacy of DR-3001 Versus Placebo in Women With Overactive Bladder
This is a placebo-controlled, double-blind study to evaluate the safety and efficacy of two doses of DR-3001 in women with overactive bladder who have symptoms of predominant or pure urge incontinence, urinary urgency and…
- Trial name
- NCT00196404
- Testing
- DR-3001a, DR-3001b
- Where
- 48 sites in United States, Canada
- Volunteers
- 800 people
- Sponsor
- Duramed Research
Urinary Bladder, Overactive
Evaluating the Change of Overactive Bladder Symptoms in Women Post Pubovaginal Sling Procedure for Stress Incontinence
Pubovaginal sling (PVS) procedures are designed to curtail bladder leakage brought about by strenuous events such as child birth.
- Trial name
- NCT01194999
- Testing
- Pubovaginal sling procedure
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- Barrie Urology Associates
Overactive Bladder, Urge Incontinence
AURA 1: Augmenting Urinary Reflex Activity: Study 1
AURA 1 (Augmenting Urinary Reflex Activity: study 1) is a study that evaluates the electrophysiological responses of pudendal nerve stimulation using short-duration extracorporeal stimulation
- Trial name
- AURA1 (NCT05256498)
- Testing
- Picostim Amber
- Sponsor
- Amber Therapeutics Ltd
Urinary Bladder, Overactive, Overactive Bladder
Vitamin D Treat-to-Target Strategy for Children With Overactive Bladder-Wet
The purpose of this clinical trial is to investigate whether adding high-dose vitamin D (2,400 IU daily) to standard medical treatment (solifenacin combined with behavioral therapy) is more effective than standard treatment alone…
- Conditions
- Urinary Bladder, Overactive, Overactive Bladder, Urinary Incontinence, Urge
- Trial name
- NCT06201013
- Testing
- urotherapy, Solifenacin Succinate, Vitamin D3
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Incontinence, Urge, Stroke
Evaluation of the Efficacy of Transcutaneous Tibial Nerve Stimulation on Post-Stroke Overactive Bladder
The goal of this clinical trial is to comparing the efficacies of different managements in patients with overactive bladder symptoms with stroke The main question it aims to answer are: Are pelvic floor training exercises and…
- Conditions
- Incontinence, Urge, Stroke, Neurogenic Bladder
- Trial name
- NCT06247033
- Testing
- Tibial Nerve Stimulation with TENS device, Pelvic muscle training exercise with bladder training
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Urinary Incontinence
Functional Assessment and Muscle Evaluation Through Exercise Trial
The purpose of this study is to decrease rates of urinary incontinence in older women by building strength in the pelvic and lower body muscle through exercise and rehabilitation.
- Trial name
- FAME (NCT03166150)
- Testing
- Multi-modal rehabilitation program, Pelvic Floor Physical therapy
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Howard University
SMAD2, SMAD3
SMAD2, SMAD3 AND TGF-β GENE EXPRESSION IN URGE URINARY INCONTINENCE
Urge urinary incontinence (UUI) is a common health problem. Changes in collagen metabolism in pelvic support organs, such as uterosacral ligaments (USLs), might be responsible for the complex pathophysiology of UUI.
- Conditions
- SMAD2, SMAD3, TGF-β, Pelvic Organ Prolapse
- Trial name
- NCT04525105
- Testing
- SMAD2
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Muğla Sıtkı Koçman University
Prostatic Hyperplasia, Urgency
Predictors of de Novo Urge Urinary Incontinence After Photoselective Vaporization of the Prostate
The aim of this study was to investigate the incidence of de novo urge urinary incontinence after the photoselective vaporization of the prostate for benign prostatic hyperplasia using the validated overactive bladder symptom…
- Conditions
- Prostatic Hyperplasia, Urgency, Urinary Incontinence
- Trial name
- NCT02243085
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- DongGuk University