Clinical trials: Urgency Urinary
Overactive Bladder
Use of Transcutaneous Posterior Tibial Nerve Stimulation (TPTNS) in Maintaining OAB Symptoms Improvement.
This study will help to determine the effectiveness of a self-supervised, home-based Transcutaneous Posterior Tibial Nerve Stimulation treatment protocol in maintaining Overactive Bladder (OAB) symptoms improvement in women…
- Trial name
- NCT02377765
- Testing
- Transcutaneous Stimulation, Percutaneus Stimulation
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Liverpool Women's NHS Foundation Trust
Benign Prostatic Hyperplasia
A Study to Track the Safety of Vesomni in Men in South Korea Treated in Routine Clinical Practice for the Urinary Symptoms of Benign Prostatic Hyperplasia (Enlarged Prostate)
Benign prostatic hyperplasia (BPH), also known as an enlarged prostate, happens more often in men as they age. This condition causes a sudden need to pass urine, which is hard to control.
- Trial name
- NCT07619105
- Testing
- Vesomni
- Volunteers
- 600 people
- Sponsor
- Astellas Pharma Korea, Inc.
Overactive Bladder
Solifenacin Plus Tadalafil vs Solifenacin Alone for Overactive Bladder in Females
Overactive bladder (OAB) is characterized by urinary urgency with or without urge urinary incontinence, usually with frequency and nocturia, in the absence of urinary tract infection or other obvious pathology.
- Trial name
- NCT07312955
- Testing
- Solifenacin, Tadalafil
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Mixed Urinary Incontinence, Stress Urinary Incontinence
The SLIM Study: Sling and Botox® Injection for Mixed Urinary Incontinence
This double-blind randomized controlled trial seeks to find a better treatment for women with mixed urinary incontinence (both stress and urgency incontinence).
- Conditions
- Mixed Urinary Incontinence, Stress Urinary Incontinence, Urgency Incontinence
- Trial name
- NCT02678377
- Testing
- OnabotulinumtoxinA (Botox ®) Injections, Saline Injections
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northwestern University
Stress Urinary Incontinence, Urge Urinary Incontinence
Age-stratified Outcome of Pelvic Floor Muscle Exercise for Urinary Incontinence
In this retrospective study the outcome of pelvic floor muscle training in 150 women will be tested regarding patients reported satisfaction and achievement of the incontinence improvement.
- Trial name
- NCT01445834
- Volunteers
- 150 people
- Sponsor
- University of Zurich
Overactive Bladder
Overactive Bladder Innovative Therapy Trial (OrBIT)
The purpose of this study is to compare percutaneous tibial nerve stimulation (PTNS) to drug therapy for the treatment of symptoms of overactive bladder (OAB).
- Trial name
- OrBIT (NCT00448175)
- Testing
- Urgent PC Neuromodulation System, Tolterodine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Uroplasty, Inc
Overactive Bladder, Urinary Urge Incontinence
Intradetrusor Botulinum Toxin A for OAB Via 1 Versus 10 Injections: A Randomized Clinical Trial
Patients with either overactive bladder (OAB) or urgency urinary incontinence (UUI) with be randomized (like a flip of a coin) to receive 100 units of bladder Botox® at either one injection site or ten injection sites.
- Conditions
- Overactive Bladder, Urinary Urge Incontinence, Overactive Bladder Syndrome, Urinary Incontinence, Urge
- Trial name
- NCT05308979
- Testing
- OnabotulinumtoxinA 100 UNT [Botox]
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Urinary Bladder, Overactive
Open-label Study of the Efficacy and Safety of VESIcare® in Patients With Overactive Bladder Symptoms
To evaluate the safety and efficacy of solifenacin succinate in subjects with overactive bladder symptoms (urgency, with or without urge incontinence, usually with frequency and nocturia).
- Trial name
- VOLT (NCT00463541)
- Testing
- solifenacin succinate
- Where
- 198 sites in United States
- Volunteers
- 2,225 people
- Sponsor
- Astellas Pharma Inc
Physiotherapy, Women's Health
Effects of External Neuromuscular Electrical Stimulation in Women With Urgency Urinary Incontinence
To reveal the effects of Neuromuscular Electrical Stimulation (NMES) applied over the thigh on incontinence symptoms, pelvic floor muscle function, bladder function, quality of life and sexual function in women with urge urinary…
- Conditions
- Physiotherapy, Women's Health, Urge Incontinence, Electrical Stimulation
- Trial name
- NCT04727983
- Testing
- Electrotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Urinary Bladder, Overactive
A Study to Assess Efficacy and Safety of the Beta-3 Agonist Mirabegron (YM178) in Patients With Symptoms of Overactive Bladder
The study is intended to test the efficacy, safety and tolerability of two doses of mirabegron against placebo to treat patients with symptoms of overactive bladder
- Trial name
- ARIES (NCT00662909)
- Testing
- Mirabegron
- Where
- 125 sites in United States, Canada
- Volunteers
- 2,149 people
- Sponsor
- Astellas Pharma Inc
Urinary Urge Incontinence
The Effects of Sacral Neuromodulation for Urinary Urgency, Frequency, and Urge Incontinence
This prospective one group cohort study seeks to investigate the effects of sacral neuromodulation on urinary urgency, frequency and urge incontinence are maintained after the simulator device is temporarily turned off for a…
- Trial name
- NCT02776475
- Testing
- Sacral neuromodulation device turned off
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- TriHealth Inc.
Incontinence, Urinary and Urinary Bladder, Overactive, Overactive Bladder
Effects Of GW679769 On Bladder Nerve Function And Symptoms Of Overactive Bladder In Spinal Cord Injury Patients
This is a two-part study in which Part A will assess the effects of GW679769 after 1 dose on the function of the nerves that supply the bladder. The technique for measuring the nerves function is called Neurometry.
- Trial name
- NCT00332319
- Testing
- GW679769
- Where
- 3 sites in United States
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Overactive Bladder, Overactive Bladder Syndrome
Defining the Safety and Efficacy of POSterIor Tibial NeRve StimulatiON in Children
The purpose of this study is to find out if overactive bladder (OAB) can be safely treated by stimulating a nerve near the ankle. This procedure is called percutaneous tibial nerve stimulation (PTNS).
- Trial name
- POSITRON-C (NCT06769854)
- Testing
- Urgent PC
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chi Dang Hornik
Urinary Urgency Incontinence
Examining Bladder Control Using Mindful Based Approach
Urgency Incontinence (where the bladder muscles contract suddenly, causing an immediate urge to urinate that is difficult to prevent) is commonly experienced in patients with overactive bladder.
- Trial name
- NCT01843543
- Testing
- Mindfulness Based Stress Reduction Course
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Oregon Health and Science University
Urgency Urinary Incontinence
eCoin Tibial Nerve Stimulation for OAB
The study is a single arm, prospective study of the safety and effectiveness of the Valencia Technologies eCoin System to stimulate the tibial nerve for the treatment of patients with refractory urgency urinary incontinence.
- Trial name
- NCT03029624
- Testing
- eCoin
- Where
- 7 sites in United States, New Zealand
- Volunteers
- 46 people
- Sponsor
- Valencia Technologies Corporation
Urinary Bladder, Overactive
Modified Extension Study to the SUmiT Trial: Evaluation of Long Term Therapy With Percutaneous Tibial Nerve Stimulation (PTNS) for Overactive Bladder Symptoms
This is a modified extension study to the SUmiT protocol UPC082008 (NCT00534521) to observe and evaluate long term therapy with PTNS on overactive bladder symptoms.
- Trial name
- STEP (NCT00928395)
- Testing
- Urgent PC
- Where
- 12 sites in United States
- Volunteers
- 50 people
- Sponsor
- Uroplasty, Inc
Overactive Bladder
Urinary Urgency Outcomes Following Propiverine Treatment for an Overactive Bladder
Overactive bladder (OAB) is defined as "urgency, with or without urge incontinence, usually with frequency and nocturia" in the absence of local pathological or endocrine factors.
- Trial name
- NCT00903045
- Testing
- Propiverine hydrochloride
- Where
- South Korea
- Volunteers
- 264 people
- Sponsor
- Samsung Medical Center
Urinary Bladder, Overactive
A Study to Test the Efficacy and Safety of the Beta-3 Agonist Mirabegron (YM178) in Patients With Symptoms of Overactive Bladder
The study is intended to test efficacy, safety and tolerability of two doses of once daily (qd) Mirabegron against placebo to treat patients with symptoms of overactive bladder.
- Trial name
- CAPRICORN (NCT00912964)
- Testing
- Mirabegron
- Where
- 151 sites in United States, Canada and 9 more
- Volunteers
- 2,030 people
- Sponsor
- Astellas Pharma Inc
Overactive Bladder
Painless Laser Therapy for Overactive Bladder
The primary objective of this study is to determine the effectiveness of transvaginally-delivered low level laser therapy (LLLT) versus Sham in the treatment of overactive bladder symptoms in women.
- Trial name
- PLTOAB (NCT01569061)
- Testing
- LCT-1000TM (Manufacturer: LiteCure)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Zipper Urogynecology Associates
Urinary Bladder, Overactive, Incontinence, Urge
Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin A
Currently, in clinical practice there has been no standardization in the number of injections a single dose of intradetrusor onabotulinumtoxin A is administered in.
- Conditions
- Urinary Bladder, Overactive, Incontinence, Urge, Incontinence, Urinary, Urinary Urge Incontinence
- Trial name
- NCT04305743
- Testing
- OnabotulinumtoxinA 100 UNT
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of South Florida