Clinical trials: Urinary Calculi
Stones, Kidney, Ureteric Injury
Intra-ureteric Aminophylline Instillation on Flexible Ureteroscopy Procedure
in this study we are going to evaluate the efficacy of intra-ureteric aminophylline instillation in facilitating ureteric access sheath placement prior to flexible ureteroscopy in reducing ureteric injury rates.
- Trial name
- NCT06830577
- Testing
- Usage of Aminophylline prior to ureteric dilatation in Flexible uretroscopy, Sequential teflon dilator usage prior to ureteric access sheath placement in flexible uretroscopy, Aminophylline instillation and Ureteral dilators together
- Where
- Egypt
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Kidney Stone
Thulium Fiber Laser Prospective Trial
This is a multi-center, prospective clinical trial to assess the effect of TFL for the lithotripsy of kidney stones.
- Trial name
- TFL (NCT05814133)
- Testing
- Thulium Fiber Laser
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
RENAL CALCULI
Safety and Efficacy of Herbmed Plus in Patients withRenal Calculi
More specifically, the present invention relates to a 'Herbal Preparation' that is useful for Treatment of Renal calculi Reduction in the stone size \& surface area The expulsion of stone Decreased need of…
- Trial name
- HerbmedPlus (NCT01355341)
- Testing
- HERBMED PLUS
- Where
- India
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Amai Charitable Trust
Kidney Stones
Oxalate-Driven Host Responses in Kidney Stone Disease
This study is looking to understand the role of oxalate on kidney stone development and immunity. This study will enroll healthy participants and participants with calcium oxalate kidney stones (CaOx KS).
- Trial name
- NCT05417568
- Testing
- Low Oxalate Diet, High Oxalate Diet
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Kidney Calculi, Ureteral Calculi
Study of Ketorolac Versus Opioid for Pain After Endoscopy
A double blind randomized controlled trial designed to compare pain control and safety with ketorolac and oxycodone in the post-operative setting for patients undergoing ureteroscopy for treatment of urinary stones.
- Trial name
- SKOPE (NCT03888144)
- Testing
- Oxycodone, Ketorolac
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Urinary Calculi, Hyperoxaluria
Proteomic Study of Urinary Stone Disease
Urinary protein levels are not routinely measured in stone patients while there is strong evidence that proteins play a role in the etiology of stones.
- Conditions
- Urinary Calculi, Hyperoxaluria, Calculi
- Trial name
- NCT00199459
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Bladder Cancer, Urocystitis
A Multicenter Clinical Trial of Urine DNA Testing for Bladder Cancer in China
The primary objective of this study is to assess the safety and effectiveness of Human Multigene Methylation Detection Kit (Fluorescent PCR Method) for help diagnose bladder cancer by comparing with clinical standard method…
- Conditions
- Bladder Cancer, Urocystitis, Urinary Bladder Stone, Urothelial Carcinoma
- Trial name
- NCT05337189
- Testing
- Urine DNA methylation analysis, medical imaging and/or cystoscopy and/or pathological examination
- Where
- China
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Kidney Stone
Can Shear Wave Elastography Predict the Success of ESWL: a Prospective Study
Can Shear Wave Elastography predict the success of Shock-Wave Lithotripsy used in renal stones treatment ? A prospective study
- Trial name
- NCT05995652
- Testing
- elastography
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Abdelrahim Elsherbiny
Pneumothorax, Intestinal Obstruction
The Impact of Artificial Intelligence-Assisted X-ray Interpretation on Radiologists' Diagnostic Performance
This study tests whether an artificial intelligence (AI) tool helps radiologists read X-rays more accurately. Radiologists read X-rays to find diseases such as pneumonia, bone fractures, and abdominal problems.
- Conditions
- Pneumothorax, Intestinal Obstruction, Spondylolysis, Renal Calculus
- Trial name
- NCT07870928
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Southern Medical University
Nephrolithiasis, Urinary Tract Infections
A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])
When patients are going to have surgery to remove large kidney stones (percutaneous nephrolithotomy [PCNL]), it is not clear whether the patients benefit from a course of prophylactic preoperative oral antibiotics; currently both…
- Trial name
- NCT02384200
- Testing
- nitrofurantoin monohydrate/macrocrystalline capsules, ampicillin, gentamicin
- Where
- 8 sites in United States, Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Ureteral Calculi, Masturbation
Rate of Spontaneous Stone Passage as Assessed Using Urinary Ultrasonography and Direct Urinary System Radiography
To evaluate the effect of masturbation on the spontaneous expulsion of distal ureteral stones 5-10 mm in size.
- Trial name
- NCT04550559
- Testing
- Endoscopic ureterolitotripsy
- Where
- Turkey (Türkiye)
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Avrasya University
Kidney Calculi, Calcium Oxalate Kidney Stones
Evaluating the Vitamin K2 Status of Calcium-based Stone Formers
This is an observation, single site-study with one study visit during which all data and samples will be collected. Study participants will be asked to provide blood, urine, and fecal samples so that the investigators may study…
- Conditions
- Kidney Calculi, Calcium Oxalate Kidney Stones, Vitamin K 2, Human
- Trial name
- NCT05081960
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Kidney Stone
A Prospective Observational Comparison of SMP and ESWL for the Treatment of Renal Stones ≥20 mm in Children (IAU-04)
ESWL and PNL are the two treatment modalities for kidney stones greater than 20 mm in the pediatric population. ESWL is non-invasive, does not require anesthesia and inexpensive, but its success rate may be lower, and require…
- Trial name
- NCT04317443
- Testing
- Super-mini percutaneous nephrolithotomy (SMP), Extracorporeal Shock Wave Lithotripsy (ESWL)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The International Alliance of Urolithiasis
Kidney Stone, Oxidative Stress
Lime Powder Regimen in Healthy Volunteers
The study aims to investigate the pharmacokinetic parameters and its antioxidative effects in Thai healthy men.
- Trial name
- LimePKphase1 (NCT01273025)
- Testing
- Lime powder regime
- Where
- Thailand
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
PCOS (Polycystic Ovary Syndrome), Stone, Urinary
Polycystic Ovary Syndrome and Urinary Tract Stones: a BMI-Adjusted Analysis in Iraqi Women
The goal of this observational case-control study is to find out the impact of PCOS as a risk factor for the presence of urinary tract stones taking into account the BMI of women aged 18-40 years consulting the gynecology and…
- Conditions
- PCOS (Polycystic Ovary Syndrome), Stone, Urinary, BMI, Obesity
- Trial name
- NCT06729359
- Testing
- Ultrasonography of the abdomen and pelvis
- Where
- Iraq
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- Al-Kindy College of Medicine
Kidney Stone
Comparing Pneumatic Versus Ultra-sonic Percutaneous Nephrolithotomy in Large Kidney Stones
The purpose of this study is to determine which type of percutaneous nephrolithotomy is better in large kidney stones
- Trial name
- NCT02751281
- Testing
- Pneumatic percutaneous nephrolithotomy, Ultra-sonic percutaneous nephrolithotomy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Kidney Stones, Urolithiasis, Hypocitraturia
Apple Cider Vinegar for the Prevention of Urinary Lithiasis (APUL)
The purpose of this study is to assess whether certain beverages can increase urinary citrate levels in healthy individuals with no history of kidney disease.
- Trial name
- APUL (NCT04073719)
- Testing
- Apple Cider Vinegar, Other Beverage
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Urinary Stone, Urinary Calculi
Ultrasound to Facilitate Stone Passage
This is a prospective, open-label, multi-center study to test the clinical feasibility of facilitating stone passage by the combination of breaking and repositioning stones with ultrasound, without the need for anesthesia.
- Trial name
- NCT04796792
- Testing
- Burst Wave Lithotripsy (BWL) and Ultrasonic Propulsion (UP)
- Where
- 3 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Washington
Urinary Stones, Ureteral Calculus
The Usefulness of Flexible Cystoscopy for Preventing Double-J Stent Malposition After Laparoscopic Ureterolithotomy
The aim of this study was to evaluate the role of flexible cystoscopy in preventing malpositioning of the ureteral stent after laparoscopic ureterolithotomy in male patients.
- Trial name
- FC-DM (NCT03150446)
- Testing
- flexible cystoscopy
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sung Gu Kang
Healthy Volunteers, Enteric Hyperoxaluria
Safety, Tolerability, and Pharmacodynamics of NOV-001 in Adult Subjects
The first stage of this study is a prospective, adaptive, Phase 1, first-in-human, randomized, controlled study evaluating safety, tolerability, and pharmacodynamics of NOV-001 in adult healthy volunteers.
- Trial name
- NCT04909723
- Testing
- NOV-001, NB1000S, NB2000P
- Where
- 20 sites in United States, Canada
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Novome Biotechnologies Inc