Clinical trials: Urinary Calculi
Kidney Stone
Evaluation of Pain Before and After Removal of Non-obstructive Kidney Stones
Pain associated with renal stone disease is typically caused by an obstructing stone that obstructs the flow of urine, which results in renal collecting system dilatation.
- Trial name
- ENORC (NCT03657667)
- Testing
- Ureteroscopy
- Where
- 9 sites in United States, Canada
- Volunteers
- 43 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Renal Calculi
Tip-flexible Semi-rigid Ureterorenoscope Versus Flexible Ureteroscopy in Renal Calculi
This study evaluates the safety and efficacy of the novel tip-flexible semi-rigid ureterorenoscope for the treatment of renal calculi using a prospective, randomized multicentre trial design.
- Trial name
- NCT02426931
- Testing
- the tip-flexible ureterorenoscope, the classic flexible ureteroscope
- Volunteers
- 280 people
- Sponsor
- Ling Li, MD
Kidney Calculi, Kidney Stone
Are the Stone Density and Location Useful Parameters for Small Kidney Stones?
The investigators aimed to evaluate whether these parameters could be guides for us in the selection of RIRS or Mini-PNL procedures in kidney stones that are smaller than 2 cm.
- Trial name
- NCT03503539
- Testing
- Mini percutaneous nephrolithotomy, Retrograde intrarenal surgery
- Volunteers
- 60 people
- Sponsor
- Abant Izzet Baysal University
Stone, Kidney, Stone Ureter
Stent Omission After Ureteroscopy and Lithotripsy in the Michigan Urological Surgery Improvement Collaborative
This is a multicenter prospective trial with randomized and observational cohorts assessing patient-reported outcomes and unplanned healthcare utilization following ureteroscopic treatment of renal and ureteral stones, with…
- Trial name
- NCT05866081
- Testing
- Standard of care stent placement, No stent placement, Surveys
- Where
- 16 sites in United States
- Volunteers
- 792 people
- Sponsor
- University of Michigan
Kidney Calculi, Ureter Calculi
Naftopidil 75mg for Improving Clearance of Urinary Stones
The purpose of this study is to evaluate Efficacy and Safety of oral intake of Naftopidil 75mg once daily for the improving clearance of ureteral or renal stones.
- Trial name
- NCT02011737
- Testing
- naftopidil 75mg
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Samsung Medical Center
Kidney Calculi
Remifentanil in Extracorporeal Shock Wave Lithotripsy
The purpose of this study is to compare the analgesic efficacy and side effects induced by administration of two different infusion rates of remifentanil, 0,05 mcg/ Kg/ min versus 0,1mcg/ Kg/ min, in order to determine which one…
- Trial name
- ESWL (NCT01452880)
- Testing
- Remifentanil
- Where
- Italy
- Volunteers
- 228 people
- Sponsor
- University of Roma La Sapienza
Nephrolithiasis, Ureteral Calculi
The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients
The purpose of this study is to determine the efficacy of the α-adrenergic antagonist tamsulosin in the treatment of adult emergency department (ED) patients with ureteral colic secondary to lower ureteral calculus.
- Trial name
- NCT00600405
- Testing
- tamsulosin, Standard therapy with ibuprofen and oxycodone.
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- MaineHealth
Urolithiasis, Urinary Tract Stones
Detection of Urinary Stones on ULDCT With Deep-learning Image Reconstruction Algorithm
Urolithiasis has an increasing incidence and prevalence worldwide, and some patients may have multiple recurrences. Because these stone-related episodes may lead to multiple diagnostic examinations requiring ionizing radiation…
- Conditions
- Urolithiasis, Urinary Tract Stones, Renal Colic, Deep Learning Reconstruction
- Trial name
- URO DLIR (NCT04490343)
- Testing
- Abdominopelvic low dose CT
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Ureteral Calculi
Comparison of Laryngeal Masks in Urethral Cystoscopic Surgery Operations: a Prospective Randomized Clinical Study
The use of Laryngeal masks are increased.This study aimed to compare lma pro seal and baska -mask in urethral retrograde sistoscopy operations.
- Trial name
- NCT04186455
- Testing
- proseal, baska-mask
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Kocaeli University
Kidney Stone
A Novel Method for Retrograde Intrarenal Surgery (RIRS)
In this prospective randomised controlled study, investigators aims to evaluate the effect of 80 mg gentamicin added to 3 liters of irrigation fluid on stone free rate, intraoperative and postoperative complications during RIRS…
- Trial name
- NCT05202158
- Testing
- Addition of gentamicin to irrigation fluid during RIRS, Only irrigation fluid during RIRS
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Training and Research Hospital
Renal Stones, Retrograde Intrarenal Surgery
Safety of Thulium Fiber Laser Litothripsy in the Management of Large Renal Stones (>1000 mm³) and Factors Affecting Treatment Success
The aim of this study is to compare the efficacy and safety of Thulium Fiber Laser (TFL) litothripsy according to stone density and the factors affecting success in patients undergoing retrograde intrarenal surgery (RIRS) for…
- Conditions
- Renal Stones, Retrograde Intrarenal Surgery, Thulium Fiber Laser
- Trial name
- RIRS and TFL (NCT07153978)
- Testing
- Effectivity of TFL on large renal stone
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Muharrem Baturu
Renal Colic, Urolithiasis
Sterile Water Injection vs Morphine for Renal Colic
This study aims to compare intradermal sterile water injections (ISWI) with intravenous morphine for pain relief in adults with acute renal colic caused by urinary stones.
- Trial name
- ISWI-Morph (NCT07378904)
- Testing
- Single Intradermal Sterile Water Injection, Multiple Intradermal Sterile Water Injections, Intravenous Morphine
- Where
- Tunisia
- Volunteers
- 150 people
- Sponsor
- University Tunis El Manar
Kidney Stone, Nephrolithiasis
Comparison of SP TFL and Ho:YAG for RIRS Using 145 µm and 200 µm Fibers
The authors hypothesize that the RIRS using 150-microm Tm-fiber laser is superior than fiber with larger diameters, as 200-microm Tm-fiber laser or 200-microm holmium fiber laser, in such points as follows: decreasing surgery…
- Conditions
- Kidney Stone, Nephrolithiasis, Urolithiasis
- Trial name
- NCT04346485
- Testing
- SP TFL RIRS with 145 mcm fiber, SP TFL RIRS with 200 mcm fiber, Ho:YAG RIRS with 200 mcm fiber
- Where
- Russia
- Volunteers
- 105 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Ureteral Calculi, Renal Calculi
Intraureteral Lidocaine for Post-Ureteroscopy Pain
Ureteroscopy (URS) is minimally invasive procedure for management of renal stones. URS is often involves concomitant of an indwelling ureteral stents.
- Trial name
- NCT01450566
- Testing
- Lidocaine, Saline
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Queen's University
Kidney Stone
Modified Supine vs Prone Position Pnl
perform a comparative randomized trial comparing the efficacy and safety of percutaneous nephrolithotomy (PCNL) in the prone and modified supine positions in management of complex renal stones
- Trial name
- NCT05379894
- Testing
- Percutaneous nephrolithotripsy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Kidney Stone
Effect of Cola on Urinary Stone Risk Factors
Examine the effects of cola on risks of kidney stones
- Trial name
- NCT00289120
- Testing
- Cola beverage, Deionized water
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Emory University
Kidney Stone
Impact of the SGLT2 Inhibitor Empagliflozin on Urinary Supersaturations in Kidney Stone Formers
The aim of this study is to test the effect of a new drug on the composition of the urine in kidney stone patients. This new drug (Jardiance®, substance: empagliflozin) is currently approved in Switzerland for the treatment of…
- Trial name
- SWEETSTONE (NCT04911660)
- Testing
- Empagliflozin 25 MG
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Kidney Stone, Healthy
Oxalate and Citrate in Humans - Response to Citrate
This is a single-center study that aims to learn more about how two compounds found in food, oxalate and citrate, interact in the body and may influence a person's chances of forming kidney stones.
- Trial name
- NCT06944223
- Testing
- Kidney stone formers, Control cohort
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Acute Calculous Anuria, Ureteral Calculi
Intravesical Aminophylline for Urgent Ureteral Stenting in Acute Calculous Anuria
Acute calculous anuria is a urological emergency caused by ureteral stone obstruction in a solitary functioning kidney or bilateral ureteral obstruction.
- Conditions
- Acute Calculous Anuria, Ureteral Calculi, Obstructive Uropathy, Acute Kidney Injury
- Trial name
- NCT07617948
- Testing
- Intravesical Aminophylline
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Beni-Suef University
Primary Hyperoxaluria Type 3
Natural History of Patients With PH3 and a History of Stone Events
This is a natural history study of adults, adolescents, and children (starting at birth) with genetically confirmed primary hyperoxaluria type 3 (PH3) who have a history of stone events during the last 3 years and/or the presence…
- Trial name
- PHYOX-OBX (NCT04542590)
- Where
- 6 sites in United States, Canada and 3 more
- Volunteers
- 7 people
- Sponsor
- Dicerna Pharmaceuticals, Inc., a Novo Nordisk company