Clinical trials: Urinary Complications
Overactive Bladder
Detrol Long Acting (LA) vs Estrace Vaginal Cream for the Treatment of Overactive Bladder Symptoms
The purpose of this study is to determine if long acting tolterodine confers more benefit than intravaginal low dose estrogen in the treatment of Overactive Bladder Syndrome at 12 weeks post-treatment initiation.
- Trial name
- DRIVE (NCT00465894)
- Testing
- Extended Release Tolterodine LA, Intra Vaginal Estradiol Cream
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Nephropathy
The Effect of Thiazide, Amiloride and Hypertonic Saline on Urinary Biomarkers in Healthy Subjects
Urinary biomarkers (u-NKCC2, u-ENaC-gamma and u-AQP2) reflects the activity of the sodium- and water channels in the human kidney.
- Trial name
- THAM (NCT01635231)
- Testing
- hypertonic saline
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Stress Urinary Incontinence
Effects of Iyengar Yoga Therapy in the Management of Stress Urinary Incontinence Among Young Females
the study is aimed to identify the feasibility, safety, and efficacy of iyengar Yoga therapy in the management of stress urinary incontinence among young female
- Trial name
- NCT04428853
- Testing
- iyengar yoga
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Pelvic Floor Muscle Weakness, Urinary Incontinence
The Effect of Pelvic Floor Exercise on Urinary Incontinence and Quality of Sex Life
This physiotherapist-guided group training programme should be performed in both the supine and the sitting positions; it is investigated, which is better and more cost-effective in patient motivation.
- Trial name
- NCT04577872
- Testing
- Pelvic floor muscle training
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Szeged University
Endometriosis Related Pain, Overactive Bladder
Study on the Safety of BAY1817080 How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given to Participants With Moderate Renal Impairment and End Stage Renal Disease Requiring Dialysis Compared With Matched Participants With Normal Renal Function
BAY1817080 is currently under clinical development to treat pain related to unexplained chronic cough or chronic cough not affected by a treatment (refractory and/or unexplained chronic cough, RUCC), or a condition where the…
- Conditions
- Endometriosis Related Pain, Overactive Bladder, Diabetic Neuropathic Pain, Refractory or Unexplained Chronic Cough
- Trial name
- NCT04471337
- Testing
- BAY1817080
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Urinary Incontinence
ProACT Therapy for the Treatment of Stress Urinary Incontinence in Males
The purpose of the study is to evaluate the safety and effectiveness of a minimally invasive surgical procedure in up to 109 male patients.
- Trial name
- ProACT (NCT00277095)
- Testing
- ProACT (Adjustable Continence Therapy)
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Uromedica
Interstitial Cystitis, Pelvic Pain
Correlating Ic/Pbs Symptoms With Urine Biomarkers
Completion of a brief survey tool and providing an urine specimen. The study purpose is to improve our understanding of interstitial cystitis and painful pelvic syndrome.
- Trial name
- NCT00817388
- Testing
- No intervention
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Urinary Incontinence
Outcomes of Urinary Incontinence Treatment in Primary Care: APP Co-Management and Electronic Consult
The burden of urinary incontinence (UI) on American women is immense in both human and financial terms, and continues to rise with the aging US population.
- Trial name
- OUTPACE (NCT06040645)
- Testing
- APP Co-management, E-consult
- Where
- 3 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Urinary Incontinence
Urban-Rural Comparison of Urinary Incontinence Impact in Women
This study will examine how urinary incontinence affects women's daily activities and quality of life in urban and rural areas. Urinary incontinence means unintentional urine leakage.
- Trial name
- NCT07669922
- Testing
- Observational assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Prostate Cancer, Adverse Effects Surgery
TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia.
- Conditions
- Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound
- Trial name
- TPF-LITT (NCT05698576)
- Testing
- TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Urological Research Network, LLC
Urinary Incontinence, Urge
Brain-Centered Therapy Versus Medication for Urgency Urinary Incontinence : Hypnotherapy Or Pharmacotherapy
This study is randomized controlled trial in which urgency incontinent women (approximately 150-160) will be randomized to hypnotherapy or pharmacotherapy and evaluated at months 2, 6 \&12 Hypotheses: Among patients with urgency…
- Trial name
- Hyp-hOP (NCT01829425)
- Testing
- Anticholinergic medications, Hypnotherapy
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Overactive Bladder, Stress, Psychological
Stress and Anxiety Effects on Overactive Bladder
The purpose of this study is to assess how psychological stress and anxiety relate to bladder sensitivity and to psychological burdens in people with overactive bladder and how this can be measured effectively.
- Conditions
- Overactive Bladder, Stress, Psychological, Anxiety
- Trial name
- NCT05087810
- Testing
- Psychological stress induction, Accelerated oral hydration
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Urinary Tract Infections, Infectious Diarrhea
Creation of an E-toileting Log Through Classification of the Physical Properties of Stool and Urine Using TrueLoo™
The purpose of this study is to assess the feasibility of TrueLoo™, an Internet-connected smart toilet seat, in accurately monitoring and logging bowel movements and urinations of residents in senior living facilities across…
- Conditions
- Urinary Tract Infections, Infectious Diarrhea, Clostridium Difficile Infection, Gastrointestinal Disease
- Trial name
- NCT05008640
- Testing
- TrueLoo™
- Where
- 6 sites in United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Toi Labs, Inc.
Phase 1, Healthy
EC905 Pharmacokinetic Profile Study
A study to compare the pharmacokinetics of tamsulosin HCl and solifenacin succinate after co-administration of single entity tablets and of the combination tablet EC905 under steady state conditions at three dose strengths.
- Conditions
- Phase 1, Healthy, Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
- Trial name
- NCT02634489
- Testing
- Tamsulosin HCl, Solifenacin Succinate, EC905
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Urinary Incontinence
Randomized Trial for Botox Urinary Incontinence
The purpose of this study is to determine how effective Botox is in reducing the amount of urine leaked and which dose of Botox is more effective and safe in those who have urinary urge incontinence.
- Trial name
- NCT00178191
- Testing
- Bladder diary, Questionnaires, Urodynamics
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Bladder Cancer, Kidney Cancer
Biomarkers in Patients With Kidney Cancer or Cancer of the Urothelium and in Healthy Participants
RATIONALE: Studying samples of blood and urine from patients with cancer and from healthy participants in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Conditions
- Bladder Cancer, Kidney Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
- Trial name
- NCT00900276
- Testing
- immunologic technique, laboratory biomarker analysis, mass spectrometry
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Renal Calculi
Ureteroscopic Laser Modality on Total Lasing Time and Total Energy in Patients With Large, Dense Renal Calculi
This study will examine the effects of ureteroscopic lasing technique (dusting, fragmentation and a hybrid approach) on total lasing time and total energy in patients with a large renal calculi burden of single or multiple stones…
- Trial name
- NCT05869890
- Testing
- MOSES laser system
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Interstitial Cystitis
Quantitative Studies of Urinary Bladder Sensation
The purpose of this study is to determine whether more than one subpopulation exists of patients with the diagnosis of Interstitial Cystitis (IC) based on sensory testing and to determine if subjects with IC have normal…
- Trial name
- NCT00903435
- Testing
- Quantitative Sensory Testing and Stimulus
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Timothy Ness, MD
Lower Urinary Tract Symptoms, Neurodevelopmental Disorders
Lower Urinary Tract Symptoms and School Functioning in Children
Children in primary school often suffer from lower urinary tract symptoms (LUTS), which may negatively impact their overall well-being.
- Conditions
- Lower Urinary Tract Symptoms, Neurodevelopmental Disorders, Incontinence, Urinary, ADHD
- Trial name
- NCT06012903
- Testing
- Questionnaire Welbevinden, Questionnaire Vancouver symptom score for dysfunctional elimination syndrome, Developmental Coordination Disorder Questionnaire
- Where
- Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent