Clinical trials: Urinary Disorders
Ultrasonography, Multiple Trauma
Keller Prehospital Ultrasound Study
The study is based on the premise that ultrasound is not commonly used in an ambulance. There are some departments that do deploy it into the field, but of those departments there is almost no data collected about its use.
- Conditions
- Ultrasonography, Multiple Trauma, Kidney Calculi, Aortic Aneurysm, Abdominal
- Trial name
- NCT01074112
- Testing
- EFAST exam, Pelvic Ultrasound, Ultrasound Guided Vascular Access
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Keller Fire Rescue
Urinary Tract Infections
Fosfomycin Versus Standard of Care in Children With Antibiotic-resistant Urinary Tract Infections
Urinary tract infections (UTIs) are among the most common bacterial infections in children. Up to 50% of UTI's are caused by multi-drug resistant ESBL-producing gram negative bacteria that do not respond to treatment with oral…
- Trial name
- FosUTI (NCT05709028)
- Testing
- Fosfomycin, Standard of care antibiotics
- Where
- 5 sites in Australia
- Volunteers
- 300 people
- Sponsor
- University of Sydney
Brain Metastasis, Bladder Cancer
Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain Metastases
For patients who have one or two metastases in the brain, the tumor(s) can often be removed with surgery to relieve symptoms from the tumor(s) and to improve survival.
- Conditions
- Brain Metastasis, Bladder Cancer, Breast Cancer, Cervical Cancer
- Trial name
- NCT00587964
- Testing
- Stereotactic Radiosurgery
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Non-muscle Invasive Bladder Cancer
Validation of a Urine-based Assay With Genomic Markers for Predicting Recurrence for Non-muscle Invasive Bladder Cancer
A study to validate, in a prospective manner, the ability of the predefined Genomic Health bladder cancer assay to detect recurrence in patients undergoing surveillance for non-muscle invasive bladder cancer.
- Trial name
- NCT02969109
- Where
- United States
- Volunteers
- 417 people
- Sponsor
- Genomic Health®, Inc.
Bladder Cancer, Spinal Cord Injury
Novel mRNA-based Urine Test for Bladder Cancer in Spinal Cord Injury Individuals
Bladder cancer is a well-recognized complication in spinal cord injury (SCI) individuals. The observed incidence rates in SCI individuals are considerably higher compared to the general population.
- Trial name
- NCT02538809
- Testing
- measurement of tumor mRNA concentration in urine
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Urodynamic Studies, Urodynamics
Urodynamics: Prone Vs. Seated Position
To demonstrate the feasibility of a pressure-flow study using a urinary condom with drainage tube in the sitting and lying position in everyday clinical practice and the comparability of the measured values with the…
- Conditions
- Urodynamic Studies, Urodynamics, Outlet Obstruction
- Trial name
- NCT06864117
- Testing
- Body position during urodynamics
- Volunteers
- 200 people
- Sponsor
- Kantonsspital Winterthur KSW
Interstitial Cystitis, Painful Bladder Syndrome
Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome
Interstitial cystitis/painful bladder syndrome (IC/PBS) is a clinical syndrome in which patients report symptoms of bladder and/or pelvic pain with pressure and/ or discomfort associated with urinary frequency and urgency.
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Painful Bladder Syndrome (PBS)
- Trial name
- NCT06096597
- Testing
- Clarix Flo
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- David Sheyn
Bladder Pain Syndrome, Interstitial Cystitis
Hypnosis for Bladder Pain Syndrome
This is a pilot randomized control trial of 30 women with interstitial cystitis/bladder pain syndrome to determine the feasibility of delivering a hypnosis intervention or usual care on bladder pain (primary outcome) and cerebral…
- Trial name
- NCT04010513
- Testing
- Hypnosis, Standard of Care
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Pennsylvania
Urinary Tract Infection
Safety and Tolerability of Ertapenem Sodium in the Treatment of Complicated Urinary Tract Infections (0826-055)
The purpose of this study is to determine the efficacy of ertapenem sodium (Invanz) in treatment of complicated urinary tract infections with respect to the proportion of patients with a favorable microbiological response at 5-9…
- Trial name
- NCT01014013
- Testing
- ertapenem sodium (MK0826), Comparator: ceftriaxone sodium
- Volunteers
- 271 people
- Sponsor
- Merck Sharp & Dohme LLC
Lower Urinary Tract Symptoms, Parkinsonism
Effect of Need to Void on Parkinsonian Gait
This study evaluates the effect of the need to void on parkinsonian gait
- Conditions
- Lower Urinary Tract Symptoms, Parkinsonism, Gait Disorders, Neurologic
- Trial name
- NCT03314610
- Testing
- Gait speed
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Pierre and Marie Curie University
Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter
Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers
This randomized clinical trial studies the Family Caregiver Palliative Care Intervention in supporting caregivers of patients with stage II-IV gastrointestinal, gynecologic, urologic and lung cancers.
- Conditions
- Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter, Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT01846520
- Testing
- educational intervention, telephone-based intervention, quality-of-life assessment
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Bladder Cancer
The Accuracy of Optic Biopsies Versus Conventional Biopsies for the Diagnosis of Superficial Bladder Neoplasia
This study evaluates the accuracy of Confocal Laser Endomicroscopy (CLE) in the diagnostic of non-invasive flat and exophytic bladder neoplasia. CLE results are compared to histopathology results.
- Trial name
- NCT02841904
- Testing
- Confocal LASER Endomicroscopy
- Where
- Denmark
- Volunteers
- 189 people
- Sponsor
- Herlev Hospital
Bladder Cancer
Chemoradiotherapy for Recurrent T1G3 Bladder Cancer
To evaluate the short term results of chemoradiation in case of T1G3 BC after BCG failure.
- Trial name
- NCT03274284
- Testing
- chemoradiation
- Volunteers
- 20 people
- Sponsor
- Assiut University
Kidney Transplantation, Kidney Disease
Prediction of Chronic Allograft Nephropathy
The investigators have shown that epithelial-to-mesenchymal transition (EMT) markers in early protocol biopsies of the renal allograft predicts the progression of fibrosis during the first year post-transplantation.
- Conditions
- Kidney Transplantation, Kidney Disease, Kidney Failure, Chronic
- Trial name
- Prefigur (NCT01380847)
- Testing
- mRNAs encoding genes
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Complicated Urinary Tract Infection, Acute Pyelonephritis
A Study of Plazomicin Compared With Levofloxacin for the Treatment of Complicated Urinary Tract Infection (cUTI) and Acute Pyelonephritis (AP)
This was a multi-center, multi-national, double-blind, randomized, comparator-controlled study of plazomicin administered intravenously compared with levofloxacin, a standard approved intravenous therapy for complicated urinary…
- Trial name
- NCT01096849
- Testing
- levofloxacin, plazomicin
- Volunteers
- 145 people
- Sponsor
- Achaogen, Inc.
Overactive Bladder
Composur: Study to Understand the Performance of Vibegron in Participants with Overactive Bladder (OAB)
This study will evaluate the treatment satisfaction, discontinuation, reasons for discontinuation, quality of life, healthcare resource utilization, and safety with Vibegron for the treatment of OAB in the context of real-world…
- Trial name
- NCT05067478
- Testing
- Vibegron
- Where
- 64 sites in United States
- Volunteers
- 403 people
- Sponsor
- Urovant Sciences GmbH
Urinary Incontinence Stress
Allogeneic Use of Expanded Mesenchymal Stem Cells Derived From Adipose Tissue (HC106), Female Urinary Incontinence Women Over 50 Years Old
Evaluate the feasibility and safety, obtaining initial efficacy data, of expanded allogeneic mesenchymal stem cells derived from adipose tissue (HC106) for the treatment of urinary incontinence in women over 50 years of age.
- Trial name
- SUITH) (NCT06738576)
- Testing
- allogeneic mesenchymal stem cells
- Where
- 6 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Superficial Bladder Cancer
ADSTILADRIN (=INSTILADRIN) in Patients With High-Grade, Bacillus Calmette-Guerin (BCG) Unresponsive Non-Muscle Invasive Bladder Cancer (NMIBC)
Previous multi-dose Phase I and Phase II clinical studies have demonstrated that ADSTILADRIN is a safe and effective treatment for BCG-refractory and recurrent NMIBC.
- Trial name
- NCT02773849
- Testing
- ADSTILADRIN
- Where
- 34 sites in United States
- Volunteers
- 157 people
- Sponsor
- Ferring Pharmaceuticals
Trauma, Urinary Tract Infections
Does a Nitrofurazone Coated Bladder Catheter Reduce the Number of Urinary Tract Infections in Trauma
Urinary tract infections occurs in trauma. We investigate whether a nitrofurazone coated can reduce the number of urinary tract infections.
- Trial name
- NCT00192985
- Testing
- Nitrofuranzone coated bladder catheter
- Where
- Denmark
- Volunteers
- 216 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Urolithiasis, Urinary Tract Stones
Detection of Urinary Stones on ULDCT With Deep-learning Image Reconstruction Algorithm
Urolithiasis has an increasing incidence and prevalence worldwide, and some patients may have multiple recurrences. Because these stone-related episodes may lead to multiple diagnostic examinations requiring ionizing radiation…
- Conditions
- Urolithiasis, Urinary Tract Stones, Renal Colic, Deep Learning Reconstruction
- Trial name
- URO DLIR (NCT04490343)
- Testing
- Abdominopelvic low dose CT
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
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