Clinical trials: Urinary Frequency More Than Once at Night
Edema Leg, Venous Insufficiency of Leg
Discovering the Effect of Venous Insufficiency on Nocturia (DEVINe)
Nocturia, or waking during the night to pass urine, is a multifactorial disease. An important cause of nocturia are peripheral edema due to accumulation of fluid in the lower limbs.
- Conditions
- Edema Leg, Venous Insufficiency of Leg, Nocturia, Bio-Impedance Measurements
- Trial name
- DEVINe Pilot (NCT03928197)
- Testing
- Tilt Test, Inbody S10, Tape measurements
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Survivorship, Prostate Cancer
An Acupuncture Study for Prostate Cancer Survivors With Urinary Issues
The purpose of this study is to test whether acupuncture can improve nocturia in prostate cancer survivors. This is the first time acupuncture is being studied for nocturia in prostate cancer survivors.
- Trial name
- NCT05540392
- Testing
- Acupuncture, Waitlist Control, Questionnaires
- Where
- 8 sites in United States
- Volunteers
- 60 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Overactive Bladder, Nocturia
NOGO for an Overactive Bladder
This is a double-blind, randomized and placebo-controlled study to evaluate the safety and effectiveness of NoGo, a standardized extract from Angelica archangelica, on overactive bladder
- Trial name
- NOGO-OAB (NCT04357223)
- Testing
- extract from Angelica archangelica leaf
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- SagaNatura
Overactive Bladder, Urge Incontinence
Effects of Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in Adults
For overactive bladder symptoms, there are numerous physiotherapy techniques have been found to be beneficial. Transcutaneous electrical stimulation of the tibial nerve is one of those treatment options, that is entirely a…
- Conditions
- Overactive Bladder, Urge Incontinence, Nocturia
- Trial name
- NCT05464589
- Testing
- Transcutaneous tibial nerve stimulation along with pelvic floor muscle srengthening, Pelvic floor muscles strengthening
- Where
- 3 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Nocturia
A Pilot Study to Evaluate PureWick for Nocturia
This is a single-center prospective pilot study of PureWick used as a management for nocturia and reduction of nighttime falls associated with going to the bathroom. Subjects are followed up to 3 months after the intervention.
- Trial name
- NCT05090722
- Testing
- PureWick System
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Nocturia
VA106483 Dose Response in Females
The purpose of this study is to describe the pharmacokinetics and pharmacodynamics of VA106483 in female subjects.
- Trial name
- NCT01171391
- Testing
- VA106483
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Vantia Ltd
Urinary Incontinence, Fecal Incontinence
Safety and Performance of UCon for the Treatment of the Symptoms of Overactive Bladder (OAB) / Bowel Dysfunction (BD)
This clinical investigation is a single-arm, prospective, multicentre, early feasibility study, which is used to evaluate the device design of UCon with respect to initial clinical safety and device performance in a small number…
- Conditions
- Urinary Incontinence, Fecal Incontinence, Urge Incontinence, Nocturia
- Trial name
- NCT05368246
- Testing
- UCon
- Where
- 3 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- InnoCon Medical
Hypertension
Nocturnal Hypertension and Nocturia in African American Men
This study to obtain pilot data on Nocturnal Hypertension and Nocturia. In Dr. Victor's current NIH grant (Cut Your Pressure Too: The LA Barbershop Blood Pressure Study) the results show that uncontrolled systolic hypertension is…
- Trial name
- NCT03048734
- Volunteers
- 19 people
- Sponsor
- Cedars-Sinai Medical Center
Bladder Dysfunction, Neurogenic Bladder Dysfunction
Feasibility Study of Transcutaneous Tibial Nerve Stimulation for Urinary Symptoms in People With Multiple Sclerosis
Neurogenic lower urinary tract dysfunction is common among people with Multiple sclerosis with a pooled prevalence of 68.41% using self-report measures and 63.95% using urodynamic studies.
- Conditions
- Bladder Dysfunction, Neurogenic Bladder Dysfunction, Urinary Incontinence, Urinary Bladder, Overactive
- Trial name
- NCT04528784
- Testing
- Transcutaneous tibial nerve stimulation
- Where
- Ireland
- Volunteers
- 23 people
- Sponsor
- University of Limerick
Parkinson's Disease, Nocturia
Melatonin for Nocturia in Parkinson's Disease
This is an an open label clinical trial of sustained-release Melatonin 2mg once daily for 12 weeks in patients with Parkinsons's Disease reporting nocturia, defined as getting up regularly at night > twice to pass urine.
- Trial name
- NCT02359448
- Testing
- Melatonin
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University College, London
Overactive Bladder (OAB), Nocturia
A Novel Wearable Transcutaneous Tibial Nerve Stimulation (TTNS) Device in the Treatment of Patients With Overactive Bladder (OAB) and Nocturia
Overactive bladder (OAB) is a syndrome with urgency as the main symptom, usually accompanied by frequent urination, nocturia, and sometimes urge urinary incontinence.
- Trial name
- NCT07635251
- Testing
- A new wearable transcutaneous tibial nerve stimulation (TTNS) device, behavioral therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Qilu Hospital of Shandong University
Patients Who Had the Urine Volume at Nighttime More Than One Third of Total Daily Urine Volume (NPU) and Voided More Than Two Times at Nighttime (Nocturia)
Necessity for Repetitive Education of Behavioral Modification
Few studies have reported the efficacy of repetitive education for behavioral modification as the first-line therapy for patients with nocturnal polyuria (NPU).
- Trial name
- NCT01280279
- Testing
- education for behavioral modification
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Seoul National University Hospital
Nocturia, Insomnia
Multi-center Trial to Improve Nocturia and Sleep in Older Adults
The Multi-center Trial to Improve Nocturia and Sleep in Older Adults (MINT) study is a randomized trial to determine and assess the efficacy of integrated treatment of coexisting nocturia and insomnia, as well as explore the…
- Trial name
- MINT (NCT06110091)
- Testing
- Integrated Behavioral Therapy Program, Health Education Program
- Where
- 2 sites in United States
- Volunteers
- 192 people
- Sponsor
- Atlanta VA Medical Center
Interstitial Cystitis
Acupuncture for the Treatment of Interstitial Cystitis (IC) Symptoms
Acupuncture is a form of Chinese medicine that has been in existence for more than a thousand years. This clinical trial performs two types of acupuncture on traditional 'bladder' points to determine if one type demonstrates…
- Trial name
- NCT00094874
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Mary Elizabeth Groff Surgical Medical Research and Education Charitable Trust
Urinary Incontinence
An Evaluation of the PureWick™ Male External Catheter Versus an Established Comparator Overnight in the Home Setting for Incontinence in Adult Males
This post-market study will assess the performance of and user satisfaction with the PureWick™ Male External Catheter in a home setting.
- Trial name
- PUREST-M (NCT07282860)
- Testing
- PureWick System, UltraFlex Self-Adhering Male External Catheter
- Where
- 15 sites in United States
- Volunteers
- 120 people
- Sponsor
- C. R. Bard
Nocturia
Comparative Trial to Investigate the Efficacy and Safety of Desmopressin for the Treatment of Nocturia in Adult Men
The purpose of the study is to investigate the efficacy and safety of two different dose levels of desmopressin orally disintegrating tablets against placebo for the treatment of nocturia in adult men during 12 weeks treatment
- Trial name
- NOC (NCT01694498)
- Testing
- A: Desmopressin 25 µg, B. Desmopressin 50 µg
- Where
- 35 sites in Japan
- Volunteers
- 183 people
- Sponsor
- Ferring Pharmaceuticals
Urinary Incontinence
Evaluation Trial of Handheld Urinal for Adult Use
Usability and efficacy evaluation of a prototype handheld urinal for adult use
- Trial name
- NCT04897932
- Testing
- RS - WP06
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Binding Sciences Limited
Nocturia
Validation of Capillary Serum Sodium Levels
Prospective interventional study to determine sodium levels in capillary blood via finger prick. The goal is to determine if this technique is suitable and equal to a standard venous blood collection for the analysis of blood…
- Trial name
- NCT05414279
- Testing
- Sodium determination
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Flank Pain, Urinary Bladder, Overactive
Therapeutic Merit of Solifenacin in the Mitigation of Ureteral Stent-induced Pain and Lower Urinary Tract Symptoms
Most ureteral stent insertions follow ureteroscopy procedures for stone management. Stents are essentially designed to prevent the blockage of the ureter.
- Trial name
- NCT01381120
- Testing
- Solifenacin succinate treatment, Oxycodone and acetaminophen combination treatment
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Barrie Urology Associates
Nocturia, Polyuria
Food and Salt Handling in Diuresis
Understanding the impact of food/nutrients on body fluid metabolism is important for improving diagnosis and treatment of nocturia, polyuria in relation to lifestyle interventions.
- Trial name
- NCT04526340
- Testing
- Blood sample, Bio-impedance measurement (BIA), Ingestion of testing nutrient/food capsules
- Where
- Belgium
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent