Clinical trials: Urinary Frequency More Than Once at Night
Nocturia
Efficacy Study of VA106483 in Males With Nocturia.
To investigate the effect of VA106483 on nocturia related clinical outcomes compared to placebo.
- Trial name
- NCT01038843
- Testing
- VA106483
- Where
- 19 sites in United States
- Volunteers
- 152 people
- Sponsor
- Vantia Ltd
Patients Who Had the Urine Volume at Nighttime More Than One Third of Total Daily Urine Volume (NPU) and Voided More Than Two Times at Nighttime (Nocturia)
Necessity for Repetitive Education of Behavioral Modification
Few studies have reported the efficacy of repetitive education for behavioral modification as the first-line therapy for patients with nocturnal polyuria (NPU).
- Trial name
- NCT01280279
- Testing
- education for behavioral modification
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Seoul National University Hospital
Over Active Bladder, Urinary Incontinence (UI)
Electroacupuncture as a Treatment for Refractory Overactive Bladder
This study is a single-site feasibility randomised controlled trial evaluating the feasibility and acceptability of electroacupuncture (EA), and percutaneous tibial nerve stimulation (PTNS), in women with refractory overactive…
- Conditions
- Over Active Bladder, Urinary Incontinence (UI), Nocturia
- Trial name
- EAOAB (NCT07124390)
- Testing
- Name: Electroacupuncture (EA) Type: Device-based acupuncture therapy, Neuromodulation therapy
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Bladder Function
A Pilot Trial in a Sleep Laboratory Setting to Observe Night Time Bladder Function of Subjects With Overactive Bladder (OAB)
This is an observational, pilot, non-treatment study to evaluate and develop clinical variables for distinguishing female OAB subjects that have detrusor overactivity positive (DO+) nocturia from female OAB subjects that have…
- Trial name
- NCT01099345
- Testing
- cystometry (CMG), polysomnography (PSG)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Astellas Pharma Inc
Nocturia
A Pilot Study to Evaluate PureWick for Nocturia
This is a single-center prospective pilot study of PureWick used as a management for nocturia and reduction of nighttime falls associated with going to the bathroom. Subjects are followed up to 3 months after the intervention.
- Trial name
- NCT05090722
- Testing
- PureWick System
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Nocturia, Benign Prostatic Hyperplasia
Efficacy and Safety of Silodosin on Nocturia for Patients With Benign Prostatic Hyperplasia
The objective of this study is to determine safety and efficacy of silodosin, which is a treatment for benign prostatic hyperplasia with high selectivity to α1A-receptor, on patients with benign prostatic hyperplasia accompanied…
- Trial name
- BPH (NCT02106182)
- Testing
- Silodosin, Laboratory tests, 3-days voiding diary
- Where
- 6 sites in South Korea
- Volunteers
- 135 people
- Sponsor
- JW Pharmaceutical
Lower Urinary Tract Symptoms
Role of PWV on Male LUTS Progression
Male lower urinary tract symptoms (LUTS) is exceedingly common in the general population. Stereotypically, male LUTS have long been attributed to the prostate.
- Trial name
- NCT04312074
- Where
- Hong Kong
- Volunteers
- 159 people
- Sponsor
- Chinese University of Hong Kong
Nocturia
Multicenter Study to Investigate SER120 Nasal Spray Formulations in Patients With Nocturia
The purpose of this study is to investigate the efficacy and safety of SER120 nasal spray formulations in patients with nocturia for a total duration of 14 weeks.
- Trial name
- NCT01357356
- Testing
- SER120 (750 ng/day), SER120 (1000 ng/day), SER120 (1500 ng/day)
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Serenity Pharmaceuticals, Inc.
Prostatic Hyperplasia
MEN STUDY (ESTUDIO MEN) Quality of Life in Patients With BPH and Nocturia Before and After Tamsulosin Ocas® Treatment
This is an exploratory study, to evaluate the improvement in terms of quality of life that can be reached by a group of outpatients with BPH ( Benign Prostatic Hyperplasia ) and nocturia when they are under treatment with Secotex…
- Trial name
- NCT00885027
- Where
- 18 sites in Colombia
- Volunteers
- 1,342 people
- Sponsor
- Boehringer Ingelheim
Nocturia
A Study of Minirin Melt in 24 Months Treatment in Patients With Nocturia
A Confirmation of the Safety Profile for Minirin Melt in Clinical Practice
- Trial name
- NCT01552395
- Where
- 68 sites in Czechia
- Volunteers
- 4,136 people
- Sponsor
- Ferring Pharmaceuticals
Nocturia
An Extension Study Investigating the Efficacy and Safety of a Fast-Dissolving ("Melt") Formulation of Desmopressin for the Treatment of Nocturia in Adults
The purpose of this study was to investigate the long term efficacy and safety of several doses of the Melt formulation of desmopressin in a broad population of adult patients with nocturia.
- Trial name
- NCT00615836
- Testing
- Desmopressin Melt
- Where
- 73 sites in United States, Canada
- Volunteers
- 554 people
- Sponsor
- Ferring Pharmaceuticals
Urinary Bladder, Overactive
Evaluating the Change of Overactive Bladder Symptoms in Women Post Pubovaginal Sling Procedure for Stress Incontinence
Pubovaginal sling (PVS) procedures are designed to curtail bladder leakage brought about by strenuous events such as child birth.
- Trial name
- NCT01194999
- Testing
- Pubovaginal sling procedure
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- Barrie Urology Associates
Nocturia, Polyuria
Food and Salt Handling in Diuresis
Understanding the impact of food/nutrients on body fluid metabolism is important for improving diagnosis and treatment of nocturia, polyuria in relation to lifestyle interventions.
- Trial name
- NCT04526340
- Testing
- Blood sample, Bio-impedance measurement (BIA), Ingestion of testing nutrient/food capsules
- Where
- Belgium
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Bladder Function
Pilot Trial in Sleep Laboratory Setting to Compare the Physiology of Night Time Bladder Function in Subjects With Overactive Bladder (OAB) Versus Subjects That Have Insomnia and Healthy Normal Subjects
This is an observational, physiology pilot study of subjects with overactive bladder, insomnia and normal subjects. No study drug will be given. All subjects will complete a one week sleep diary and a 3-day bladder diary.
- Trial name
- Nocturia Plt 1 (NCT01029015)
- Testing
- cystometry, polysomnography
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Interstitial Cystitis
Acupuncture for the Treatment of Interstitial Cystitis (IC) Symptoms
Acupuncture is a form of Chinese medicine that has been in existence for more than a thousand years. This clinical trial performs two types of acupuncture on traditional 'bladder' points to determine if one type demonstrates…
- Trial name
- NCT00094874
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Mary Elizabeth Groff Surgical Medical Research and Education Charitable Trust
Nocturia, Insomnia
Multi-center Trial to Improve Nocturia and Sleep in Older Adults
The Multi-center Trial to Improve Nocturia and Sleep in Older Adults (MINT) study is a randomized trial to determine and assess the efficacy of integrated treatment of coexisting nocturia and insomnia, as well as explore the…
- Trial name
- MINT (NCT06110091)
- Testing
- Integrated Behavioral Therapy Program, Health Education Program
- Where
- 2 sites in United States
- Volunteers
- 192 people
- Sponsor
- Atlanta VA Medical Center
Lower Limb Lymphedema, Urogenital Cancer
Lymphoedema and Nocturia/ Nocturnal Polyuria After Pelvic Lymph Node Dissection for Urogenital Cancer
After the treatment of urogenital cancer, a person may develop lymphoedema of the leg(s) and/ or midline region. Lymphoedema is the result of a dysfunction in the lymphatic system and is characterized by excessive retention of…
- Trial name
- UroLymph (NCT05266157)
- Testing
- Manual lymph drainage, Usual care
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Urinary Bladder, Overactive, Incontinence, Urge
Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin A
Currently, in clinical practice there has been no standardization in the number of injections a single dose of intradetrusor onabotulinumtoxin A is administered in.
- Conditions
- Urinary Bladder, Overactive, Incontinence, Urge, Incontinence, Urinary, Urinary Urge Incontinence
- Trial name
- NCT04305743
- Testing
- OnabotulinumtoxinA 100 UNT
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of South Florida
Overactive Bladder
Solifenacin Plus Tadalafil vs Solifenacin Alone for Overactive Bladder in Females
Overactive bladder (OAB) is characterized by urinary urgency with or without urge urinary incontinence, usually with frequency and nocturia, in the absence of urinary tract infection or other obvious pathology.
- Trial name
- NCT07312955
- Testing
- Solifenacin, Tadalafil
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Nocturia
Trial of Desmopressin Orally Disintegrating Tablets (ODT) for Nocturia Due to Nocturnal Polyuria in Japanese Male Subjects
The purpose of this trial is to demonstrate efficacy of desmopressin ODT against placebo for the treatment of male subjects with nocturia due to nocturnal polyuria, during 12 weeks of treatment.
- Trial name
- NCT02904759
- Testing
- Desmopressin
- Where
- Japan
- Volunteers
- 342 people
- Sponsor
- Ferring Pharmaceuticals