Clinical trials: Urinary Lithiasis
Renal Colic, Ureter Stone
Role of Antihistaminic in Acute Renal Colic Prevent Pain Recurrence and Expulsion of Ureteric Stone ≤ 1cm
Urolithiasis is one of the most common urological diseases. The risk of stone disease ranges between 5% and 12% worldwide. Ureteric stones account for ≈20% of all urinary tract stones and >70% of the ureteric stones are located…
- Trial name
- NCT05150899
- Testing
- Tamsulosin Hcl 0.4Mg Cap, fexofenadine 180 mg Oral tablet
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Kidney Stone, Kidney Calculi
The Impact of Nutritional Service in the Stone Clinic on the Patient Urine Collection Results
Kidney stone disease has become a common phenomenon in the US and Europe with a growing incidence of about 10%. Life style and dietary changes have a cardinal part in kidney stone prevention.
- Trial name
- NUT1 (NCT04545528)
- Testing
- Dietary recommendations
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Renal Stone
Comparison of Different Analgesia Drug Regimens for Pain Control During ESWL for Renal Stones
We want to compare the effect of lignocaine 2 % gel, Naproxen sodium and their combination on the pain control during extracorporial shock wave lithotripsy for renal stones.
- Trial name
- NCT02786446
- Testing
- Lidocaine gel,, Naproxen Sodium, Lidocaine gel and Naproxen Sodium
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Shifa International Hospital
Kidney Stone, Normal Controls
Oxalate and Citrate
This is a single-center study that aims to earn more about how two different compounds found in food, oxalate and citrate, may affect a person's chances of forming kidney stones.
- Trial name
- NCT05334979
- Testing
- Kidney stones Normal controls Consuming a special drink (sodium oxalate) during an all day visit to the University of Chicago research clinic
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Ureteral Stone, Urolithiasis
Phosphodiesterase 5 Inhibitors (PDE5i) (Sildenafil) as Medical Expulsive Therapy in Distal Ureteral Stones
Urolithiasis is one of the most common urological diseases. The risk of urolithiasis is estimated to be between 5% and 12% all over the world with increased incidence in male rather than female (2:1) respectively .
- Trial name
- NCT02519153
- Testing
- Sildenafil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Urolithiasis
Parents' Health-Education Handbook in Preventing Pediatric Urolithiasis Formation
The aim of this study is to estimate the role of Parents' Health-Education Handbook in preventing pediatric urolithiasis. This study is designed as an unmatched clusters randomized intervention trial.
- Trial name
- NCT04284241
- Testing
- Parents'Health-Education Handbook
- Where
- China
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Guohua Zeng
Urolithiasis, Intrarenal Pressure
Renal Structural and Functional Alterations Following Repeated Ureteroscopic Procedures: An Exploratory Multimodal Imaging Study
Introduction and objectives Saline irrigation and instrumentation during Retrograde Intrarenal Surgery (RIRS) causes elevation of intrarenal pressure (IRP) inducing intrarenal backflow (IRB).
- Conditions
- Urolithiasis, Intrarenal Pressure, MRI Scans, Scintigraphy Quantification
- Trial name
- BackFlow2 (NCT07913178)
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Region of Southern Denmark
Nephrolithiasis, Staghorn Calculus
Impact of Tranexamic Acid Use in Percutaneous Nephrolithotomy
This study is a double blinded randomized controlled trial evaluating the impact of tranexamic acid use on the transfusion rate in patients with complex kidney stones undergoing percutaneous nephrolithotomy.
- Trial name
- NCT02966236
- Testing
- Tranexamic Acid
- Where
- Brazil
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hematuria, Bladder Ca
Efficacy of the Act of Urination to Relief the Pain During Flexible Cystoscopy Procedure.
This research is about modification during routine cystoscopy (scope in the bladder) procedure [ experimental research ]. The goal of the study is to evaluate patient experience with cystoscopy by using procedural modification to…
- Conditions
- Hematuria, Bladder Ca, Bladder Stone, Urologic Diseases
- Trial name
- NCT05207969
- Testing
- Instruction to urinate
- Where
- Malaysia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Lithiasis, Urinary
Study of the Effects of the Consumption of Different Products Cocoa Derivatives at the Risk of Crystallization of Uric Acid in Urine of Volunteers.
The present study aims to assess the effectiveness of theobromine, -product present in high proportion in the cacao-, to prevent the development of uric acid kidney stones.
- Trial name
- NCT03512600
- Testing
- Intervention 0, Intervention 1, Intervention 2
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Devicare S.L.
Renal Stone
Percutaneous Nephrolithotomy for Treatment of Kidney Stones Greater Than 2 cm
Percutaneous nephrolithotomy (PCNL) is a minimally invasive procedure considered as the treatment of choice for the management of large-scale and fully-formed kidney stones.This procedure has a 5% risk of complications including…
- Trial name
- NCT03189264
- Testing
- percutaneous nephrolithotomy for kidney stones
- Where
- Colombia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr Carlos Hernández
Renal Stone
Comparison Between External Oblique Intercostal Block and Erector Spinae Plane Block in PCNL
The aim of the study is to compare the post-operative analgesic effect of USG unilateral External oblique intercostal (EOI) block with Erector spinae plane block (ESPB) for after percutaneous Nephrolithotomy with a hypothesis…
- Trial name
- NCT06131151
- Testing
- External Oblique Intercostal Block, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University
Kidney Stone
Influence of Obesity on Endogenous Oxalate Synthesis
There is increasing evidence that obesity is associated with increased urinary oxalate excretion, an important risk factor for calcium oxalate stone formation.
- Trial name
- NCT03704350
- Testing
- controlled diet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Urolithiasis
Multi-Center Comparison of Dual Lumen Versus Single Lumen Ureteroscopes
Urolithiasis (kidney stones) is a common disease process affecting people all across the world. Usually, if the stone size is small, it is able to pass through the urinary system and exit the bladder on its own with no treatment.
- Trial name
- NCT02123082
- Testing
- Storz single Lumen Ureteroscope, Dual Lumen Ureteroscope
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Stone;Renal
Flexible Ureteroscopy Versus Mini-Percutaneous Nephrolithotomy for Treatment of Renal Stones
Management of nephrolithiasis is evolving rapidly, and various minimally-invasive urological procedures are currently available for treating patients with renal stones, including extracorporeal shockwave lithotripsy (ESWL)…
- Trial name
- NCT03932370
- Testing
- Flexible ureteroscopy, mini-Percutaneus nephrolithotomy
- Where
- Egypt
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Assiut University
Urolithiasis
The Effects of Sports Drinks on Urinary Lithogenicity
The effect of sports drinks on the tendency to form kidney stones has not been assessed. Patients will drink 1 liter a day of 2 sports drinks and collect urine to determine changes in urine chemistry that may decrease the risk of…
- Trial name
- NCT00381277
- Testing
- Gatorade, Performance
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- VA New York Harbor Healthcare System
Ureter Calculi
The Effect of Acupuncture on Passing Ureteral Stones
Ureteral stones are a common condition, especially small and distal stones, and can cause renal colic pain. Medical expulsive therapy (MET) is widely used to facilitate stone passage.
- Trial name
- NCT07893431
- Testing
- medical expulsive therapy (tamsulosin), Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hitit University
Stone;Renal, Stone, Kidney
Ureteral Stenting After Ureteroscopy for Stone Treatment, A Global Perspective on Indications and Outcomes
Background: The exit strategy after ureteroscopy for stone treatment remains a topic for discussion. Current EAU guidelines on urolithiasis state that postoperative stenting is indicated in patients at increased risk of…
- Conditions
- Stone;Renal, Stone, Kidney, Stone Ureter
- Trial name
- NCT03567421
- Where
- 50 sites in United States, China and 13 more
- Volunteers
- 2,348 people, healthy volunteers welcome
- Sponsor
- Société Internationale d'Urologie
Kidney Stone
Protein Kinase 2 (HIPK2) Polymorphisms on rs2058265, rs6464214, and rs7456421
In the present study investigators aimed to investigate whether homeodomain interacting protein kinase 2 (HIPK2) polymorphism is associated with renal stone formation in Turkish population or not.
- Trial name
- NCT04804436
- Testing
- Genetic analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Stones, Kidney, Ureteric Injury
Intra-ureteric Aminophylline Instillation on Flexible Ureteroscopy Procedure
in this study we are going to evaluate the efficacy of intra-ureteric aminophylline instillation in facilitating ureteric access sheath placement prior to flexible ureteroscopy in reducing ureteric injury rates.
- Trial name
- NCT06830577
- Testing
- Usage of Aminophylline prior to ureteric dilatation in Flexible uretroscopy, Sequential teflon dilator usage prior to ureteric access sheath placement in flexible uretroscopy, Aminophylline instillation and Ureteral dilators together
- Where
- Egypt
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Ain Shams University