Clinical trials: Urinary Stones
Nephrolithiasis, Kidney Stone
ClearPetra™ Vacuum-assisted Ureteral Access Sheath vs Traditional Approach
Ureteroscopy has been considered the best approach when treating renal stones smaller than 2 cm. This procedure is usually performed together with ureteral access sheaths, which helps protect the ureter mucosa and lowers…
- Trial name
- VA-UAS vs trad (NCT06547632)
- Testing
- ClearPetra Ureteral access sheath
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Stone Ureter
Extra-Corporeal Shock Wave Lithotripsy for Renal and Upper Ureteral Stones in Adults Under Locally Infiltrate d Anaesthetics ; a Clinical Randomized Controlled Study
There are many treatment modalities available for managing renal and upper ureteric stones. They range from completely non-invasive outpatient procedures to invasive procedures requiring hospital admission and increased risks of…
- Trial name
- NCT06462573
- Testing
- locally infilterating anaethesia like lidocaine, general anaethesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Kidney Stones
Alfuzosin for Medical Expulsion Therapy of Ureteral Stones
The goal of this study is to conduct a prospective controlled trail of four currently approved Department of Defense (DOD) - formulary medications for use as medical expulsion therapy (MET) for kidney stones.
- Trial name
- MET (NCT00713739)
- Testing
- Alfuzosin, nifedipine, doxazosin
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Urolithiasis
Management of Ureteral Calculi Using Ultrasound Guidance: A Radiation Free Approach
Kidney stones are very common, and can inflict a significant degree of pain and renal damage. Some stones become obstructed in the ureter, the tube that drains the kidney.
- Trial name
- NCT01792765
- Testing
- Ultrasound guidance
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Kidney Stones
AR Projections for Eye-gaze Evaluation in Phantoms
This project aims to develop an augmented reality (AR) tool to enhance skill acquisition for endoscopic kidney stone surgery. Of the 100,000 patients who undergo an endoscopic kidney stone treatment annually in the United States…
- Trial name
- NCT07161024
- Testing
- Augmented reality
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Pediatric ALL
Quality of Life for Pediatric Urolithiasis
The aim of this study is to assess the quality of life (QoL) in pediatric patients with urinary stone disease.
- Trial name
- Elattar (NCT06092203)
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Urolithiasis
Litholytic Therapy for Coral Urate Nephrolithiasis
This is a prospective cohort study, patients with coralloid nephrolithiasis. Purpose of the study: to evaluate the efficacy and safety of litholytic therapy of coral-like urate nephrolithiasis with citrate mixtures.
- Trial name
- NCT07162974
- Testing
- anhydrous citric acid - 1197.0 mg, potassium bicarbonate - 967.5 mg, sodium citrate anhydrous - 835.5 mg
- Where
- Russia
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Moscow State University of Medicine and Dentistry
Renal Calculi
Evaluation of Prevalence, Molecular and Genetic Backgrounds of Calcium-Based Stones Among Patients With Renal Calcular Disease in Mansoura Urology and Nephrology Center
Evaluation of Prevalence, Molecular and Genetic Backgrounds of Calcium-Based stones among Patients with Renal Calcular Disease in Mansoura Urology and Nephrology Center
- Trial name
- NCT05972408
- Testing
- percutaneous nephrlolithotomy, VDR gene, CASR gene
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Anesthesia, Intraocular Pressure
Intraocular Pressure, Optic Nerve Sheath Diameter and Optic Perfusion Pressure of Minimal Low and High-Flow Anesthesia
The aim of this clinical trial is to determine the effect of minimal low-flow versus high-flow anesthesia on intraocular pressure (IOP) by non-contact tonometry, optic nerve sheath diameter (ONSD) by USG and optic perfusion…
- Conditions
- Anesthesia, Intraocular Pressure, Nephrolithiasis
- Trial name
- NCT06684704
- Testing
- minimal and high flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Urolithiasis
Effect of Vinegar Consumption on 24-hour Urinary Risk Factors Associated With Stone Formation
Purpose: The aim of this present study is to investigate the effect of vinegar consumption on 24-hour urinary risk factors associated with calcium oxalate urinary stone formation and blood biochemical parameters.
- Trial name
- NCT02649140
- Testing
- Vinegar group
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Stone
Influence of Obesity on Oxalate Metabolism and Handling in Calcium Oxalate Stone Formers
The primary goals of this study are to determine the contribution of dietary oxalate absorption, renal oxalate handling, and endogenous oxalate synthesis to urinary oxalate excretion in normal Body Mass Index (BMI) and obese…
- Trial name
- NCT04333745
- Testing
- Controlled Diet, Carbon-13 Oxalate and Sucralose Ingestion
- Where
- 2 sites in United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Fasting, Chronic Disease
A Retrospective and Prospective Cohort Study of the 21-day Fasting-like Diet in Patients With Metabolic and Autoimmune Diseases
Effectiveness of fasting or fasting-mimicking diet has been proved an effective approach to treat metabolic and autoimmune diseases in mice.
- Conditions
- Fasting, Chronic Disease, Autoimmune Diseases, Metabolic Disease
- Trial name
- NCT03193177
- Testing
- the 21-day fasting-like diet
- Where
- China
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Tsinghua University
Urinary Stones
Acoustic Enhancer Research on Laser Lithotripsy (AEROLITH)
A pivotal study to evaluate the safety and effectiveness of Applaud Acoustic Enhancer when used in conjunction with conventional ureteroscopic laser lithotripsy (URS-LL) in the treatment of subjects with urinary stones.
- Trial name
- AEROLITH (NCT04563039)
- Testing
- Ureteroscopy Laser Lithotripsy (URS-LL) with Acoustic Enhancer, Standard Ureteroscopic Laser Lithotripsy
- Where
- 23 sites in United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Avvio Medical
Stone, Kidney
Evaluation of Retrograde Intra Renal Surgery in the T-tilted Position
To evaluate the effect of the T-tilted position on the stone-free rate compared to the standard lithotomy position in retrograde intrarenal surgeries.
- Trial name
- RIRS (NCT06860113)
- Testing
- T-tilting of the patient during surgery, standard lithotomy position
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Renal Calculi
FANS VS DISS in Treatment of Renal Stone < 2cm
To compare between FANS \& DISS in : Operative time Stone free rate Complications Amount of fluid irrigation
- Trial name
- NCT07559214
- Testing
- Flexible ureteroscopy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Kidney Stones
Differential Effect of Silodosin Versus Tamsulosin on Stone Clearance After Extra-corporeal Shock Wave Lithotripsy
Tamsulosin is an alpha blocker usually prescribed for urinary complaints that has been shown to have some benefit in allowing kidney stones to pass through the ureter.
- Trial name
- NCT01560091
- Testing
- silodosin, Extra-corporeal shock wave lithotripsy, Tamsulosin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Calculus of Upper Urinary Tract (Disorder)
The Impact of Renalof® Dietary Supplement on Upper Urinary Tract Stone Volume
Following informed consent, all recruited patients will have a baseline non-contrast CT scan performed at the radiology department of "G.
- Trial name
- AMMOS (NCT04860492)
- Testing
- Renalof 325mg
- Where
- Greece
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Ureteral Stones
Is Prophylactic Antibiotics Necessary In Otherwise Healthy Adult Patients Undergoing Ureteroscopic Procedures for Ureteral Stones?
The present study aims to investigate the relative efficacy, safety and risk of a single-dose prophylaxis in otherwise healthy adult patients undergoing ureteroscopic procedures for ureteral stones.
- Trial name
- NCT02635490
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Renal Colic, Acute Renal Failure
Urinary Markers for Unilateral Kidney Obstruction
Renal colic is usually caused from an obstructing stone along the ureter. Some of the patients present with a high level of creatinin in the blood, even though there is a normal functioning contralateral kidney.
- Trial name
- NCT01979042
- Where
- Israel
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Ureteral Calculi
Comparing Uretersocopy With Versus Without Use of Guide-wire in Treatment of Ureteral Stone
The purpose of this study is to compare ureteroscopy with and without use of safety guide-wire in treatment of ureteral stone
- Trial name
- NCT03726502
- Testing
- ureteroscopy with safety guide-wire, ureteroscopy alone, without safety guide-wire
- Where
- Iran
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences