Clinical trials: Urinary Stones
Urinary Tract Stones
Multicenter Study to Develop a Model to Identify Uric Acid Urinary Tract Stones Using CT and Lab Tests
Urinary tract stones are a common condition affecting the kidney, ureter, bladder, and urethra. Uric acid stones represent an important subtype of urinary stones and require different prevention and treatment strategies compared…
- Trial name
- UAS-Model (NCT07328932)
- Testing
- No intervention (observational study)
- Where
- China
- Volunteers
- 1,650 people
- Sponsor
- Jian Zhuo
Stone;Renal, Stone, Urinary
Comparison Between Two Methods for Renal Stone Treatment Mini Percutaneous Nephrolithotomy and Flexible Ureteroscopy With Suction Sheath
This study aims to compare the efficacy and safety of two modern, minimally invasive surgical techniques for the removal of kidney stones: Mini-Percutaneous Nephrolithotomy (Mini-PCNL) and Flexible Ureteroscopy (FURS) with…
- Conditions
- Stone;Renal, Stone, Urinary, Stone, Kidney, Stone Clearance
- Trial name
- mini-PCNL/FANS (NCT07306819)
- Testing
- mini-percutaneous nephrolithotomy, Flexible Uerteroscopy with Tip-Bendable Suction Sheath
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Stone, Kidney, Stone, Urinary
FANS-FURS vs Suction Mini-PCNL for 2-3 cm Renal Stones: A Multicenter Randomized Trial
This multicenter, prospective, randomized clinical trial compares FANS-assisted flexible ureteroscopy (FURS) with suction-assisted mini-percutaneous nephrolithotomy (mini-PCNL) for the treatment of renal stones measuring 2-3 cm.
- Trial name
- NILE (NCT07295860)
- Testing
- FANS-Based Flexible Ureteroscopy (FURS), Suction-Assisted Mini-PCNL
- Where
- 9 sites in Egypt
- Volunteers
- 254 people
- Sponsor
- Mansoura University
Urinary Stone, Urinary Calculi
Ultrasound to Facilitate Stone Passage
This is a prospective, open-label, multi-center study to test the clinical feasibility of facilitating stone passage by the combination of breaking and repositioning stones with ultrasound, without the need for anesthesia.
- Trial name
- NCT04796792
- Testing
- Burst Wave Lithotripsy (BWL) and Ultrasonic Propulsion (UP)
- Where
- 3 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Washington
Ureteric Stone, Flexible Ureteroscopy
Flexible vs Semi-rigid URS
To compare the efficacy, safety, success rate, operative time, and cost-effectiveness of flexible ureteroscopy versus semirigid ureteroscopy in the management of upper ureteric stones smaller than 2 cm.
- Conditions
- Ureteric Stone, Flexible Ureteroscopy, Upper Urinary Tract Stones
- Trial name
- NCT07247617
- Testing
- Flexible URS, Semi-Rigid URS
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Urinary Tract Infections, Kidney Stone
Asymptomatic Renal Calculi in Recurrent Urinary Tract Infections
This study will assess patients who have recurrent urinary tract infections and kidney stones which are not blocking the kidney or causing other problems.
- Trial name
- NCT04495699
- Testing
- None - observational
- Where
- 6 sites in United States, Canada
- Volunteers
- 94 people
- Sponsor
- Vanderbilt University Medical Center
Kidney Stone
Evaluation of Emergency Computed Tomography in Suspected Renal Colic. This is an Observational Retrospective Study Aimed to Evaluate Emergency Computed Tomography in Patients at the Emergency Department in Helsingborg, Sweden, With Suspected Acute Renal Colic.
The goal of this observational study is to learn more about diagnostics in patients with suspected acute renal colic at the emergency department.
- Trial name
- NCT06805149
- Where
- Sweden
- Volunteers
- 1,500 people
- Sponsor
- Region Skane
Urinary Stone, Renal Colic
Radiomics and Image Segmentation of Urinary Stones by Artificial Intelligence
Kidney stone disease causes significant morbidity, and stones obstructing the ureter can have serious consequences. Imaging diagnostics with computed tomography (CT) are crucial for diagnosis, treatment selection, and follow-up.
- Conditions
- Urinary Stone, Renal Colic, Obstruction Ureter, Urosepsis
- Trial name
- RISUS_AI (NCT06412900)
- Where
- Norway
- Volunteers
- 522 people
- Sponsor
- Oslo University Hospital
Urinary Tract Stone
Effectiveness of WhatsApp Education and Support Messages for Urolithiasis Prevention
Kidney and ureteral stones are a common problem in primary care practice with increasing prevalence over the last few decades. Prevention of recurrent stones (which are usually composed primarily of calcium oxalate) is aimed at…
- Trial name
- StoneApp (NCT05627622)
- Testing
- WhatsApp health education message
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Bladder Stone
Percutaneous Versus Transurethral Cystolithotripsy For The Management Of Bladder Calculi In The Pre-school Boys
Bladder stones are an uncommon condition in children, accounting for only 5% of urolithiasis in developed countries, whereas in developing nations, a greater number of children are affected due to the high incidence of urinary…
- Trial name
- NCT06970587
- Testing
- percutaneous cystolithotripsy
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- South Valley University
Urinary Tract Infection Complicated, Kidney Stones
Resistance Characteristics and Development of Diagnostic Model for Postoperative UTI in Patients With Kidney Stones
The combined detection of HBP, ADPN, NGAL, and hs-CRP enables the construction of a highly efficient diagnostic model, offering a novel strategy for early infection identification and risk stratification after surgery.
- Conditions
- Urinary Tract Infection Complicated, Kidney Stones, Antimicrobial Resistance
- Trial name
- NCT06946667
- Testing
- the UTI group, the Non-UTI group
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Xingxin Jiang
Urinary Stones
Acoustic Enhancer Research on Laser Lithotripsy (AEROLITH)
A pivotal study to evaluate the safety and effectiveness of Applaud Acoustic Enhancer when used in conjunction with conventional ureteroscopic laser lithotripsy (URS-LL) in the treatment of subjects with urinary stones.
- Trial name
- AEROLITH (NCT04563039)
- Testing
- Ureteroscopy Laser Lithotripsy (URS-LL) with Acoustic Enhancer, Standard Ureteroscopic Laser Lithotripsy
- Where
- 23 sites in United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Avvio Medical
Bladder Cancer, Bladder Stone
A Study Comparing a Disposable Flexible Cystoscope With Reusable Scopes in Adult Patients.
This study will compare the time required for a cystoscopy procedure in adult participants using the Redpine® Rflex endo(trademark) High-Definition Cystoscope or the site's standard of care reusable flexible cystoscope in…
- Conditions
- Bladder Cancer, Bladder Stone, Bladder Outlet Obstruction, Renal Stone
- Trial name
- NCT06422312
- Testing
- Cystoscopy with RedPine flexible disposable cystoscope, Cystoscopy with standard of care flexible reusable scope
- Where
- 3 sites in United States
- Sponsor
- Guangzhou Red Pine Medical Instrument Co., Ltd.
Bladder Cancer, Urocystitis
A Multicenter Clinical Trial of Urine DNA Testing for Bladder Cancer in China
The primary objective of this study is to assess the safety and effectiveness of Human Multigene Methylation Detection Kit (Fluorescent PCR Method) for help diagnose bladder cancer by comparing with clinical standard method…
- Conditions
- Bladder Cancer, Urocystitis, Urinary Bladder Stone, Urothelial Carcinoma
- Trial name
- NCT05337189
- Testing
- Urine DNA methylation analysis, medical imaging and/or cystoscopy and/or pathological examination
- Where
- China
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
PCOS (Polycystic Ovary Syndrome), Stone, Urinary
Polycystic Ovary Syndrome and Urinary Tract Stones: a BMI-Adjusted Analysis in Iraqi Women
The goal of this observational case-control study is to find out the impact of PCOS as a risk factor for the presence of urinary tract stones taking into account the BMI of women aged 18-40 years consulting the gynecology and…
- Conditions
- PCOS (Polycystic Ovary Syndrome), Stone, Urinary, BMI, Obesity
- Trial name
- NCT06729359
- Testing
- Ultrasonography of the abdomen and pelvis
- Where
- Iraq
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- Al-Kindy College of Medicine
Urinary Tract Stones, Pain
Pain and Anxiety During Extracorporeal Shock Wave Lithotripsy
Investigators observed that during the Extracorporeal Shock Wave Lithotripsy (ESWL) non-pharmacological methods used for reducing the level of the pain and anxiety among the patients with the urinary stones are not sufficient and…
- Conditions
- Urinary Tract Stones, Pain, Anxiety
- Trial name
- NCT02725281
- Testing
- Stress ball, Music
- Volunteers
- 120 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Urosepsis, Urinary Tract Stone
Urosepsis in Patients With Urinary Tract Calculi Receiving Surgical Intervention
Urosepsis is one of major cause of the overall sepsis leading to high morbidity and mortality, which commonly resulted from urinary tract calculi.
- Trial name
- NCT05317273
- Where
- Thailand
- Volunteers
- 865 people
- Sponsor
- Mahidol University
Urinary Stone
Two Types of Single-use Flexible Ureteroscopies for the Treatment of Upper Urinary Tract Stones in Children
The single-use digital flexible Ureteroscopy (fURS) is commonly used for the treatment of upper urinary tract stones. The size of the outer diameter of the fURS can affect the safety, efficacy, and medical costs of the treatment.
- Trial name
- NCT06628765
- Testing
- 8.6 Fr single-use fURS (XFGC-FU-660RC), 6.3 Fr single-use fURS (Hugemed, HU30S)
- Where
- China
- Volunteers
- 52 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Recurrent Calcium Oxalate Kidney Stone Disease, Elevated Urinary Oxalate Levels
A Study to Evaluate Lumasiran in Adults With Recurrent Calcium Oxalate Kidney Stone Disease and Elevated Urinary Oxalate Levels
The primary purpose of this study is to evaluate the effect of lumasiran on the percent change in urinary oxalate excretion in patients with recurrent calcium oxalate kidney stone disease.
- Trial name
- NCT05161936
- Testing
- Lumasiran
- Where
- 31 sites in United States, Belgium and 4 more
- Volunteers
- 2 people
- Sponsor
- Alnylam Pharmaceuticals
Urinary Stone
Feasibility Study of an Enhanced Lithotripsy System in the Treatment of Urinary Stone Disease
This is a single arm, single center study to assess the safety and efficacy of a form of extracorporeal lithotripsy, called the Enhanced Lithotripsy System, to treat urinary stones.
- Trial name
- NCT03195920
- Testing
- Enhanced Lithotripsy System
- Where
- India
- Volunteers
- 3 people
- Sponsor
- Avvio Medical