Clinical trials: Urinary Symptoms
Nocturia, Prostatic Hyperplasia
A Study of Silodosin 8 mg Daily for the Treatment of Nocturia in Men With Benign Prostatic Hyperplasia
Silodosin is compared to placebo to determine if it is safe and effective for the treatment of nighttime urination (nocturia) in men with BPH
- Trial name
- NCT00793819
- Testing
- silodosin
- Where
- 27 sites in United States
- Volunteers
- 215 people
- Sponsor
- Watson Pharmaceuticals
Overactive Bladder, Urge Urinary Incontinence
Safety and Applicability Study of a Novel Heat Flow Sensor Unit for Measuring Urinary Bladder Capacity
A novel sensor (a device named sensurine)was developed in the aim of real- time measurement of bladder volume. The sensurine device is a wearable, fully passive, non-invasive and compact heat flow sensor (patent pending) and…
- Conditions
- Overactive Bladder, Urge Urinary Incontinence, Enuresis, Self Clean Intermittent Catheterization
- Trial name
- NCT00437528
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Overactive Bladder
Use of Transcutaneous Posterior Tibial Nerve Stimulation (TPTNS) in Maintaining OAB Symptoms Improvement.
This study will help to determine the effectiveness of a self-supervised, home-based Transcutaneous Posterior Tibial Nerve Stimulation treatment protocol in maintaining Overactive Bladder (OAB) symptoms improvement in women…
- Trial name
- NCT02377765
- Testing
- Transcutaneous Stimulation, Percutaneus Stimulation
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Liverpool Women's NHS Foundation Trust
Stress Urinary Incontinence
Effect of Different Pelvic Floor Loading Techniques on Women With Stress Urinary Incontinence
The purpose of this study is to compare the effects of different pelvic floor loading techniques (graduated positions versus graduated weights) on women with stress urinary incontinence.
- Trial name
- NCT07661264
- Testing
- Graduated loading positions, Graduated Vaginal Weights (Vaginal Cones)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Urinary Incontinence, Spinal Cord Injury
Lumbar to Sacral Ventral Nerve Re-Routing
To assess the level of improvement in voiding function after lumbar to sacral ventral nerve re-routing procedure in Spinal Cord Injury and spina bifida patients
- Conditions
- Urinary Incontinence, Spinal Cord Injury, Spina Bifida
- Trial name
- NCT00378664
- Testing
- lumbar to sacral ventral nerve re-routing procedure
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Kenneth Peters, MD
Stress Urinary Incontinence
The Altis® Single Incision Sling System for Female Stress Urinary Incontinence Study
An international, multi-center, single arm, prospective clinical study designed to assess the safety and efficacy of the Coloplast Altis single incision sling system for females with stress urinary incontinence (SUI).
- Trial name
- NCT01272284
- Testing
- Altis® Single Incision Sling System (SIS)
- Where
- 17 sites in United States, Canada
- Volunteers
- 113 people
- Sponsor
- Coloplast A/S
Prostate Cancer
Symptomatic Study Investigating Degarelix in Patients Suffering From Prostate Cancer
The purpose of this trial was to see how well a new trial drug (degarelix) worked on lower urinary tract symptoms (also known as LUTS) in prostate cancer patients as compared to how a standard drug hormonal treatment worked on…
- Trial name
- NCT00831233
- Testing
- Degarelix, Goserelin, Bicalutamide
- Where
- 33 sites in Germany, Spain and 1 more
- Volunteers
- 42 people
- Sponsor
- Ferring Pharmaceuticals
Overactive Bladder
Long Term Study To Evaluate the Safety, Tolerability and Efficacy of Fesoterodine for Overactive Bladder.
To assess the long term safety, tolerability and efficacy of fesoterodine in patients with OAB.
- Trial name
- NCT00658684
- Testing
- fesoterodine fumarate
- Where
- 12 sites in Japan
- Volunteers
- 153 people
- Sponsor
- Pfizer
Neurogenic Bladder
Toxin Retrospective Study
Aims of this study were to assess the long-term outcomes of detrusor injection of OnabotulinumtoxinA (Botox® injection) associated with clean intermittent-catheterization (CIC) for the treatment of neurogenic detrusor…
- Trial name
- NDOTOX (NCT03042052)
- Testing
- detrusor infection of Botulinum toxin
- Where
- France
- Volunteers
- 292 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Overactive Bladder
Clinical Trial to Evaluate the Efficacy and Safety of Fesoterodine in Comparison to Tolterodine for Overactive Bladder (OAB)
To evaluate the efficacy and safety of fesoterodine in comparison to tolterodine and placebo for overactive bladder
- Trial name
- NCT00444925
- Testing
- fesoterodine fumarate, tolterodine tartrate
- Where
- 178 sites in United States, Belgium and 27 more
- Volunteers
- 1,712 people
- Sponsor
- Pfizer
Cancer, Sarcoma
EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors
This Phase 1/2 study evaluates the safety, tolerability, and preliminary anti-tumor activity of EBNK-001 (allogeneic NK cells) given after lymphodepleting cyclophosphamide/fludarabine (CY/FLU) and supported with low-dose IL-15…
- Conditions
- Cancer, Sarcoma, Leukaemia, Breast Cancer (Locally Advanced or Metastatic)
- Trial name
- EBNK-ST-001 (NCT07410676)
- Testing
- EBNK-001 + IL-15 + Pembrolizumab
- Where
- China
- Volunteers
- 83 people
- Sponsor
- Essen Biotech
Chronic Interstitial Cystitis
Pentosan Polysulfate Treatment's Effectiveness
To examine the relationship between symptoms and quality of life before and after oral pentosan polysulfate (PPS) treatment in cases diagnosed with interstitial cystitis/painful bladder syndrome (IC/BPS).
- Trial name
- NCT05744908
- Testing
- Pentosan Polysulphate
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hisar Intercontinental Hospital
Reusable Underwear, Urinary Incontinence, Dispoable Pad
Randomized Controlled Crossover Comparison of Icon Underwear to Disposable Pads
This is a randomized cross over trial to compare quality of life and product performance between Icon reusable underwear versus standard disposable pad in patients with mild to moderate urinary incontinence.
- Trial name
- NCT03263676
- Testing
- Icon resuable underwear, Disposable pad
- Volunteers
- 70 people
- Sponsor
- Medstar Health Research Institute
Stress Urinary Incontinence, Urinary Incontinence
Precise Transvaginal Tape Placement Trial
This purpose of this study is to study is to see if intra-operative urethral length measurement with the Foley catheter will improve the placement of a synthetic sling in the mid-urethra.
- Trial name
- NCT02101489
- Testing
- Foley Catheter
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Loyola University
Overactive Bladder, Parkinson Disease
Mirabegron for Treatment of Overactive Bladder Symptoms in Patients With Parkinson's Disease
The purpose of this study is to see the study drug, Mirabegron, is safe and effective in treating symptoms of Overactive Bladder in patients with Parkinson's disease.
- Trial name
- NCT03412513
- Testing
- Mirabegron
- Where
- 5 sites in South Korea
- Volunteers
- 144 people
- Sponsor
- Seoul National University Hospital
Prostate Cancer, Adverse Effects Surgery
TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer
This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia.
- Conditions
- Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound
- Trial name
- TPF-LITT (NCT05698576)
- Testing
- TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Urological Research Network, LLC
Kidney Stone
LithoVue Single Use Disposable Ureteroscope
Most flexible ureteroscopes that are used to treat kidney stones have been reusable. Recently, advances in technology have resulted in single-use (disposable) ureteroscopes to become available.
- Trial name
- NCT03419091
- Testing
- single-use flexible digital ureteroscope, Reusable Ureteroscope
- Where
- 2 sites in United States, Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Lower Urinary Tract Symptoms
Bladder Wall Blood Perfusion Pattern and Sexual Dysfunction in Female Patients With Lower Urinary Tract Symptoms, and the Association of That Perfusion Pattern and Therapeutic Efficacy of Antimuscarincs for Female Overactive Bladder Syndrome.
Overactive bladder syndrome (OAB) affects around 17 % of female population. However, the etiology of OAB is complicated and unclear in many aspects.
- Trial name
- NCT01282840
- Testing
- Tolterodine SR
- Where
- Taiwan
- Volunteers
- 676 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Urinary Incontinence
Physical Exercise and Bladder Training Program for Urinary Incontinence
The overall objective of this project is to reduce the risk of falls in elderly community dwelling women over 60 years of age with urgency urinary incontinence (UUI).
- Trial name
- NCT03869918
- Testing
- Exercise Program
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Pennsylvania
Kidney Stones
Surgical Outcomes and Costs in Using the Shenzhen HugeMed 6.3 French Flexible Ureteroscope
Comprehensive comparative investigations between HugeMed HU30M 6.3 Fr f-URS and traditional approach f-URS devices in RIRS are lacking in an American population.
- Trial name
- NCT07296835
- Testing
- Ureteroscopy using the 6.3 Fr f-URS hugemed, Hugemed 6.3 Fr f-URS
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Kansas Medical Center