Clinical trials: Urinary Tract Disease
Pain, Postoperative, Ureter Stone
Local Anaesthetic and Steroid in the Ureter
Précis: Randomised control trial to evaluate safety and efficacy of intraluminal injection of high pH-high concentration of a long-acting local anesthetic and long-acting glucocorticoid in the ureter after ureteroscopy.
- Trial name
- LASTE (NCT03296189)
- Testing
- Levobupivacaine, Dexamethasone Sodium Phosphate
- Where
- Ireland
- Volunteers
- 150 people
- Sponsor
- The Adelaide and Meath Hospital, incorporating The National Children's Hospital
Acute Kidney Injury, Sepsis
Doppler Ultrasound for Prediction of Reversibility of Acute Kidney Injury in Septic ICU Patients
Purpose: The aim of this study was to assess the ability of early discrimination between transient and persistent Acute Kidney Injury (AKI) using the color Doppler Ultrasound derived Renal Resistive Index (RI) and…
- Conditions
- Acute Kidney Injury, Sepsis, Renal Resistive Index
- Trial name
- NCT03597074
- Testing
- color Doppler Ultrasound derived RI and semi-quantitative evaluation of intra-renal vascularization
- Where
- Greece
- Volunteers
- 32 people
- Sponsor
- Aristotle University Of Thessaloniki
Acute Pancreatitis, Pancreatitis
Study of Copeptin as a Diagnostic Marker for Acute Pancreatitis
The purpose of this study is to investigate if there is an association between copeptin level in serum and the severity of pancreatitis and if copeptin can be used as a predictor for organ failure and pancreatic necrosis with or…
- Trial name
- COPA (NCT01293318)
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University Hospital, Basel, Switzerland
Secondary Hyperparathyroidism, Chronic Kidney Disease
Study to Evaluate the Effects of Zemplar Injection and Calcijex on Intestinal Absorption of Calcium
A study to investigate the effects of Zemplar and Calcijex on intestinal calcium absorption in hemodialysis subjects.
- Trial name
- NCT00073710
- Testing
- Zemplar, 42 Ca carbonate absorption via single tracer method, Calcijex
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Abbott
Autosomal Dominant Polycystic Kidney Disease
NOX4 and Related Biomarkers in ADPKD
To determine the value of NOX4, markers of mitochondria injury and function, and oxidative stress as real-time biomarkers to assess disease severity in patients with early autosomal dominant polycystic kidney disease (ADPKD).
- Trial name
- NCT04630613
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Insulin Pump Therapy in Treating Diabetic Nephropathy
Effect Insulin Pump Therapy to Patients With Diabetic Nephropathy
The recent study suggested that oxidative stress resulting from increased production of reactive oxygen species (ROS) plays a crucial role in the development of diabetic complications.
- Trial name
- NCT03174821
- Testing
- Insulin pump
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Urinary Retention, Healthy Vollunteer
Identification of Urinary Retention by Simplified Ultrasound: Diagnostic Without Volumetric Measurements
Urinary retention is a urological emergency that requires prompt management to prevent complications such as acute kidney injury or bladder rupture.
- Trial name
- GUS (NCT07841821)
- Testing
- Bladder ultrasound
- Where
- Belgium
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
End Stage Liver Disease, End Stage Renal Disease
Transplant and Addiction Project (TAP) - 1
The purpose of this study is to test a novel distance-based (telephone) intervention to help transplant candidates with current or recent substance abuse to stay "clean and sober" both prior and following transplant surgery.
- Conditions
- End Stage Liver Disease, End Stage Renal Disease, Substance-Related Disorders
- Trial name
- NCT00249652
- Testing
- TAP, TAU
- Where
- 3 sites in United States
- Volunteers
- 41 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
End Stage Renal Disease
Comparison of the Impact of Dialysis Treatment Type on Patient Survival
As the influence of type of dialysis on survival of end stage renal disease (ESRD) patients remains unanswered, the present study is designed (randomized, prospective, multicenter, interventional) to assess clinical outcomes, and…
- Trial name
- NCT00510549
- Testing
- Modality: Peritoneal Dialysis
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Baxter Healthcare Corporation
IGA Nephropathy
A Study of Treatment Patterns and Real-World Outcomes in IgA Nephropathy Patients in the United States
The aim of this study was to characterize real-world treatment patterns, including therapy sequences, escalation, and duration, and treatment outcomes in IgA nephropathy (IgAN) patients in the United States (US).
- Trial name
- NCT07757048
- Where
- United States
- Volunteers
- 6,286 people
- Sponsor
- Novartis Pharmaceuticals
Diabetic Nephropathies, Hyperhomocysteinemia
The Effect of Folic Acid Administration in the Progression of Microalbuminuria
The development of diabetic nephropathy has been linked to several genetic polymorphisms, including those related with homocysteine metabolism such as the methylenetetrahydrofolate reductase (MTHFR)and the…
- Trial name
- NCT00737126
- Testing
- Folic acid
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Parkinson's Disease, Overactive Bladder
Safety and Efficacy of Botulinum Toxin A for Treatment of Overactive Bladder in Parkinson's Disease
A randomized controlled trial is to be conducted to confirm the efficacy and safety of intramuscular injection of botulinum toxin in the treatment of Parkinson's bladder overactivity.
- Conditions
- Parkinson's Disease, Overactive Bladder, Onabotulinumtoxin A
- Trial name
- NCT05997043
- Testing
- oral anti-Parkinson drugs and injection of botulinum toxin, oral anti-Parkinson's drugs
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhujiang Hospital
Sickle Cell Trait, Sickle Cell Disease (SCD)
Sickle Cell Kidney Biorepository
Kidney disease is a major cause of illness and death in people with sickle cell disease and sickle cell trait. Despite these concerning facts, we do not (1) have an in-depth understanding of how kidney disease starts in sickle…
- Conditions
- Sickle Cell Trait, Sickle Cell Disease (SCD), Chronic Kidney Disease
- Trial name
- SCeK (NCT07064174)
- Where
- 2 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pulmonary Disease, Chronic Obstructive
Study to Assess the Safety and PK of GSK573719 and GSK573719/GW642444(VI) Combination in Healthy Subjects and Subjects With Severe Renal Impairment
This study will assess the safety and pharmacokinetics of inhaled GSK573719 and GSK573719/vilanterol combination in healthy subjects and in subjects with severe renal impairment.
- Trial name
- NCT01571999
- Testing
- Inhaled GSK573719, Inhaled GSK573719/vilanterol
- Where
- 2 sites in Czechia, Hungary
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
End-Stage Renal Disease
Effect of Different Hemodialysis Modality on Adiponectin,Vascular Function and Clinical Prognosis
Adiponectin, an adipose tissue derived protein, with anti-inflammatory properties that is secreted from adipose tissue, is associated with insulin resistance.
- Trial name
- NCT00155363
- Testing
- conventional artificial kidney (AK) vs. high flux AK
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Acute Kidney Injury
Early Versus Late Renal Replacement Therapy After Cardiac Surgery
The question of timing of initiation of renal replacement therapy (RRT), "early" versus "late", has seldom been the focus of high-quality or rigorous evaluation.
- Trial name
- NCT01961999
- Testing
- Early RRT, Late RRT
- Where
- Italy
- Volunteers
- 1,800 people
- Sponsor
- Ospedali Riuniti Ancona
Renal Failure
Daptomycin Study - Collection of Pharmacokinetic Samples in Patients With Renal Failure
This will be a prospective, multicenter, open-labeled, non-comparative pharmacokinetic study conducted in 10 critically ill, anuric patients receiving CVVHDF. Enrollment will take place at 3-5 clinical sites in the United States.
- Trial name
- NCT00573898
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Pittsburgh
AKI
Deep Learning Model and Risk Factors for Tacrolimus-related Acute Kidney Injury
In this study, the investigators aim to develop a risk prediction model for acute kidney injury (AKI) in hospitalized patients using the calcineurin inhibitor tacrolimus.
- Trial name
- NCT06596798
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital
Kidney Failure, Chronic, Hepatitis C
Safety of Sofosbuvir in People With Advanced Kidney Failure
Infection with hepatitis C virus (HCV), a hepatotropic RNA virus, is often chronic, and causes liver cirrhosis and liver cancer. The virus is transmitted through parenteral exposure.
- Trial name
- NCT03883698
- Testing
- Sofosbuvir, Daclatasvir 60 mg
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Advanced Kidney Cancer
Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Kidney Cancer
This is a phase II Randomized comparison clinical trial of activated CIK armed with anti-CD3-MUC1 bispecific antibody for advanced kidney cancer.
- Trial name
- NCT03540199
- Testing
- Activated CIK and CD3-MUC1 Bispecific Antibody in Treating Kidney Cancer, cryotherapy
- Where
- China
- Sponsor
- Fuda Cancer Hospital, Guangzhou
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