Clinical trials: Urinary Tract Infection(UTI)
Urinary Infections
Study of the Pharmacokinetics of Ceftriaxone
Urinary tract infections (UTIs) are the leading cause of community-acquired bacterial infections in adults. They are a common reason for admission to the Emergency Department (ED), particularly when pyelonephritis is suspected.
- Trial name
- Etude PC-IUU (NCT07169097)
- Testing
- free ceftriaxone concentration dosage
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Rouen
Kidney Transplantation, Adult
Web-Based Multi-Resource Training on the Prevention of Urinary Tract Infections in Adult Kidney Transplant Recipients
Purpose: The study aims to examine the effect of web-based multi-source training on the prevention of urinary tract infections in adult kidney transplant recipients on clinical outcomes.
- Conditions
- Kidney Transplantation, Adult, Urinary Tract Infections, Prevention
- Trial name
- NCT05821946
- Testing
- Web-Based Multi-Source Training on the Prevention of Urinary Tract İnfections
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Urinary Tract Infection Symptomatic, Acute Pyelonephritis
Safety and Efficacy of ZTI-01 (IV Fosfomycin) vs Piperacillin/Tazobactam for Treatment cUTI/AP Infections
The purpose of the study is to demonstrate the safety and efficacy of ZTI-01 (IV fosfomycin) as non-inferior to piperacillin/tazobactam in overall success (clinical cure and microbiologic eradication) for the treatment of…
- Conditions
- Urinary Tract Infection Symptomatic, Acute Pyelonephritis, Urinary Tract Infection Complicated
- Trial name
- ZEUS (NCT02753946)
- Testing
- ZTI-01, Piperacillin-tazobactam
- Where
- 68 sites in United States, Belarus and 14 more
- Volunteers
- 465 people
- Sponsor
- Nabriva Therapeutics AG
Recurrent Urinary Tract Infection
Study to Evaluate the Efficacy of Lactobacillus Crispatus M247 in the Prevention of Recurrent Urinary Tract Infections
This randomized, open-label, controlled clinical trial evaluates the efficacy and safety of Lactobacillus crispatus M247 (CRISPACT®) in preventing recurrent urinary tract infections (rUTIs) in women.
- Trial name
- NCT06857565
- Testing
- Lactobacillus crispatus M247, iNatal-Duo® (containing Bifidobacterium animalis subsp. lactis BB-12 and Enterococcus faecium L3)
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Complicated Urinary Tract Infection, Acute Pyelonephritis
Meropenem-FL058 Phase 2 Study in the Treatment of Complicated Urinary Tract Infections
Phase 2, randomised, double-blind,double-dummy study in hospitalised adults with complicated urinary tract infection (cUTI), including acute pyelonephritis.Treatment duration for each cohort was 7 to 14 days.
- Trial name
- NCT05060419
- Testing
- Meropenem- FL058, Piperacillin -tazobactam, Saline
- Volunteers
- 150 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Overactive Bladder
Pilot Study: Is Overactive Bladder Caused by Subacute Urinary Tract Infections?
The purpose of this study is to look for evidence of bacteria in the urine or bladder of people with overactive bladder. Because you do not have overactive bladder, your participation in this study will be used as a comparison to…
- Trial name
- NCT00714792
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Infectious Disease
Temocillin in ESBL-Enterobacteriaceae Infections
Because of the increasing incidence of infections with multi-drug resistant enterobacteriaceae, we need alternative treatments to spare carbapenems.
- Trial name
- TMO2016 (NCT05413772)
- Testing
- Temocillin
- Where
- 2 sites in France
- Volunteers
- 29 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vesicoureteral Reflux (VUR), Urinary Tract Infection
Polyacrylate Polyalcohol Copolymer for Vesicoureteral Reflux
Endoscopic correction of VUR has gained its popularity due to its less invasiveness, associated low morbidity and short hospital stay.
- Trial name
- NCT01926353
- Where
- Philippines
- Volunteers
- 25 people
- Sponsor
- St. Luke's Medical Center, Philippines
Otitis Media, Urinary Tract Infection
ParentLink: Better and Safer Emergency Care for Children
The emergency department (ED) constitutes a high-risk environment for errors and poor quality of care. Pediatric patients are at increased risk of medical errors.
- Conditions
- Otitis Media, Urinary Tract Infection, Asthma, Head Injury
- Trial name
- NCT00457600
- Testing
- patient-driven health IT product
- Where
- 2 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Boston Children's Hospital
Recurrent Urinary Tract Infection
Phase II Clinical Trial of Vitamin D3 for Reducing Recurrence of Recurrent Lower Urinary Tract Infections
The aim of this study was to initially evaluate the optimal dose, efficacy, and safety of vitamin D3 for reducing recurrence of recurrent urinary tract infections (rUTIs).
- Trial name
- NCT04859621
- Testing
- Vitamin D3 4000 IU, Vitamin D3 2000 IU, standard antibiotic therapy
- Where
- 6 sites in China
- Volunteers
- 150 people
- Sponsor
- Zensun Sci. & Tech. Co., Ltd.
Urinary Tract Infections
Antimicrobial Stewardship in UTIs in Nursing Homes
Background: The widespread inappropriate use of antimicrobial substances drives resistance development at the individual and population level all over the world.
- Trial name
- NCT04798365
- Testing
- Intervention group
- Where
- 4 sites in Austria
- Volunteers
- 326 people
- Sponsor
- Medical University of Graz
Febrile Urinary Tract Infection
Pivmecillinam as Oral Step-Down Treatment for Escherichia Coli Febrile Urinary Tract Infection Versus Standard of Care
The goal of this clinical trial is to learn if oral treatment with pivmecillinam is effective to treat febrile urinary tract infections in adult patients.
- Trial name
- PIVOT (NCT07236944)
- Testing
- Pivmecillinam, Standard of Care (Investigator Choice)
- Where
- 13 sites in Norway, Sweden
- Volunteers
- 560 people
- Sponsor
- Uppsala University
Urinary Tract Infections, Catheter Infection
Noble Meta Alloy Coated Catheters in Patients With Long Term Catheterization
Eighty percent of nosocomial UTI caused by indwelling urinary catheters and so known-as catheter-associated UTI. CAUTI leads to multiple local and systemic derangements such as suprapubic pain, dysuria, cystitis, pyelonephritis…
- Conditions
- Urinary Tract Infections, Catheter Infection, Catheter-Related Infections, Infection
- Trial name
- NCT04825314
- Testing
- Urethral catheter
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Health Belief Model, Education
The Relationship Between Nurse-Led Health Belief Model-Based Education and Genital Hygiene and UTI Prevention Attitudes
Objective: This study seeks to enhance the hygiene awareness of students receiving education in the healthcare field, contributing to the development of healthy lifestyle habits.
- Trial name
- Education (NCT06891404)
- Testing
- Nurse-Led Health Belief Model-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Urologic Diseases, Urinary Tract Infections
Effect of Comprehensive Spa Care on Kidney and Urological Conditions: A Clinical Study in Adult Patients
This is a single-arm, pretest-posttest study evaluating the effects of a 21-day comprehensive spa care (Komplexní lázeňská léčebně rehabilitační péče, KLP) on patients with nephrological and urological conditions treated at a spa…
- Conditions
- Urologic Diseases, Urinary Tract Infections, Nephrolithiasis, Nephrocalcinosis
- Trial name
- Uro-Nefro (NCT07435844)
- Testing
- Comprehensive Spa Care, Exercise Therapy, Dietotherapy
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Institute of Spa and Balneology, public research institution
Bacteriuria, Urinary Tract Infection
Restricted Reporting for Positive Urine Cultures
Asymptomatic bacteriuria (AB) is a condition in which bacteria are detected in urine culture without urinary symptoms. The inappropriate use of antibiotic treatment for AB selects bacterial flora to express resistance mutations.
- Trial name
- NCT02797613
- Testing
- Restricted Reporting
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Memorial University of Newfoundland
Infection Control
Preventability of Infections in Residents of French Nursing Homes
STUDY HYPOTHESIS : An infection prevention program adapted for the nursing home context can reduce by 5% the number of infections (urinary, upper and lower respiratory and gastrointestinal) in elderly residents in nursing homes.
- Trial name
- ENLIL (NCT01069497)
- Testing
- Prevention of infections program
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Observatoire du Risque Infectieux en Gériatrie
Postoperative Retention of Urine, Postoperative Urinary Tract Infection
Day Zero Urinary Catheter Removal in Gen Thoracic Surgery Patients
Current standard of practice in study institution dictates day of surgery urinary catheter removal in general thoracic surgery patients receiving thoracic epidural analgesia.
- Trial name
- NCT01309529
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Memorial Health System
Spinal Cord Injury, Urinary Tract Infection
Colonizing Neurogenic Bladders With Benign Flora
The purpose of the research is to determine whether we can get harmless bacteria to live in the bladders of persons with spinal cord injury who practice intermittent bladder catheterization.
- Trial name
- NCT00371631
- Testing
- Insertion of urinary catheters coated with E. coli 83972
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- US Department of Veterans Affairs
Bacterial Vaginosis, Oxaluria
The Effects of Cranberry Juice on Bacterial Adhesion
The study is based on the hypothesis that consumption of cranberry juice products results in the production of metabolites in the urine that have anti-adhesive properties on bacteria.
- Trial name
- NCT00318253
- Testing
- cranberry juice
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's