Clinical trials: Urinary Tract Infection, Recurrent
Recurrent Urinary Tract Infection
Probiotics for Girls With Recurring Urinary Tract Infections
Probiotics are dietary supplements containing potentially beneficial bacterial strains such as Lactobacillus. The safety of oral administration of probiotics has been demonstrated in hundreds of studies using adults over the last…
- Trial name
- NCT00789464
- Testing
- Lactobacillus reuteri DSM 17938, trimethoprim/sulfamethoxazole
- Where
- United States
- Sponsor
- Baylor College of Medicine
Urinary Tract Infections, Chronic Urinary Tract Infection
Expanded Access Program Using Uromune for Patients With Recurrent Urinary Tract Infections (rUTI)
An Expanded Access Program for UROMUNE® for patients suffering from recurrent/chronic urinary tract infections of diverse etiology.
- Conditions
- Urinary Tract Infections, Chronic Urinary Tract Infection, Recurrent Urinary Tract Infection, Urinary Tract Infection Bacterial
- Trial name
- NCT04173013
- Testing
- Uromune
- Where
- 15 sites in Belgium, Czechia and 13 more
- Sponsor
- Impatients N.V. trading as myTomorrows
Urinary Tract Infection
Effects of Cranberry-Containing Products in Women With Recurrent Urinary Tract Infections (UTIs)
The purpose of this study is to determine the role of cranberry-containing products in preventing urinary tract infections (UTIs).
- Trial name
- NCT00100061
- Testing
- Cranberry juice
- Where
- Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Urinary Tract Infections
Cranberry Juice for the Prevention of Recurrent Urinary Tract Infections
This study will determine whether cranberry juice is effective in reducing recurrent urinary tract infections (UTIs) in women who have had a UTI within the past year.
- Trial name
- NCT00128128
- Testing
- Cranberry juice cocktail
- Where
- 2 sites in United States
- Volunteers
- 176 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Bladder Cancer, Brain and Central Nervous System Tumors
High-dose ICE With Amifostine
The purpose of the study is to evaluate the combination of amifostine and high dose chemotherapy with blood stem cell support. Amifostine is a druf developed to protect normal tissues against the toxicities of chemotherapy and…
- Conditions
- Bladder Cancer, Brain and Central Nervous System Tumors, Carcinoma of Unknown Primary, Extragonadal Germ Cell Tumor
- Trial name
- NCT00003657
- Testing
- filgrastim, Amifostine, Carboplatin
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Dana-Farber Cancer Institute
Urinary Tract Infections
Identification of Predictive Blood Biomarkers of Recurrent Urinary Tract Infections
Urinary tract infections affect more than 130 million people worldwide each year. Almost 50% of women will have at least one urinary tract infection during their lifetime, usually cystitis.
- Trial name
- Predict-UTI (NCT03819712)
- Testing
- Collection of blood samples, Collection of fecal samples, Collection of urine samples
- Where
- France
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Urinary Tract Infections, Recurrent
Bovine Colostrum for Prophylaxis Against Recurrent Urinary Tract Infection in Children
Prebiotics as bovine colostrum are considered as a valuable supplement in the prevention of upper respiratory tract infections, gastrointestinal tract infections and neonatal sepsis.
- Conditions
- Urinary Tract Infections, Recurrent, Child, Prevention & Control
- Trial name
- NCT06164600
- Testing
- Bovine colostrum
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Recurrent Urinary Tract Infections
Retrospective Analysis of Ialuril vs. Standard of Care in Recurrent Urinary Tract Infections
The purpose of this study is to assess the effectiveness and costs associated with the intravesical administration of combined hyaluronic acid (HA) and chondroitin sulphate (CS) compared to the current standard management of…
- Trial name
- RAISC-RUTI (NCT02016118)
- Testing
- Ialuril
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Study Group for Urogenital Diseases, Italy
Urinary Tract Infections
Nutraceutical Efficacy for rUTI
This is a study designed to evaluate the efficacy of a nutraceutical as a non-antibiotic treatment to prevent recurrent urinary tract infections in women that have completed menopause and are on vaginal estrogen therapy.
- Trial name
- NCT03395288
- Testing
- D-Mannose
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Washington University School of Medicine
Recurrent Urinary Tract Infection
D Mannose in Recurrent Urinary Tract Infections
Background- In recurrent urinary tract infections (RUTIs) usual prophylactic antibiotic regimes do not change the long term risk of recurrence. Objective- D-Mannose is a sugar, it sticks to E.
- Trial name
- NCT01808755
- Testing
- D Mannose, trimethoprim/sulfamethoxazole
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Recurrent Urinary Tract Infection
The Effect of Methenamine Hippurate to Reduce Antibiotic Prescribing in Elderly Women With Recurrent UTI
Recurrent urinary tract infection (UTI) in elderly women is a major driver of antibiotic prescription. Hence, the question of feasible and appropriate preventive measures are important issues in this field.
- Trial name
- ImpresUWP3 (NCT04077580)
- Testing
- Methenamine Hippurate 1000 MG
- Where
- 4 sites in Netherlands, Norway and 2 more
- Volunteers
- 289 people
- Sponsor
- University of Oslo
Recurrent Urinary Tract Infection, Hypoestrogenism
Adherence to Vaginal Estrogen Therapy in Hypoestrogenic Women With Recurrent Urinary Tract Infections
The goal of this clinical trial is to learn about medication adherence to difference types of vaginal estrogen in women with low levels of estrogen (for example, post-menopausal women) who have recurrent urinary tract infections.
- Trial name
- NCT06353269
- Testing
- Estring Vaginal Product, Vagifem, Estrace 0.01% Vaginal Cream
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Recurrent Urinary Tract Infection, Vaginal Atrophy
Prevention of Recurrent UTI Using Vaginal Testosterone Versus Placebo Placebo
Women over the age of 60 years have an estimated 10 to 15 % risk of recurrent urinary tract infections (UTI). This is believed to be due to hormonally induced changes in the vaginal flora associated with menopause.
- Conditions
- Recurrent Urinary Tract Infection, Vaginal Atrophy, Postmenopausal Disorder
- Trial name
- PIVoT (NCT04807894)
- Testing
- Vaginal Cream with Applicator
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Jefferson Drapkin
E.Coli Infections
Vaccine Against Escherichia Coli Infection
This Phase I multi-center placebo controlled study is conducted in healthy women with a history of recurrent urinary tract infections (UTI) aged between 18 and 70 years.
- Trial name
- NCT02289794
- Testing
- E.coli bioconjugate vaccine
- Where
- Switzerland
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- GlycoVaxyn AG
Urinary Tract Infections
Observational Study With Mode of Action-Analysis of Cystorenal Cranberry Extract in Patients With Recurrent Urinary Tract Infections
The main focus of this observational study is to analyze the possible effects of cranberry dietary supplements on the intestinal microbiota in women with recurrent uncomplicated urinary tract infections.
- Trial name
- NCT03019874
- Testing
- Cranberry Extract
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Charite University, Berlin, Germany
Urinary Tract Infections
Clinical Assessment of Urinary Antiseptics Methenamine and Methylthioninium in Recurrent Cystitis
This is a double-blind, randomized, double-dummy, comparative study in parallel groups of subjects presenting with recurrent cystitis (≥2 episodes within the past 6 months).
- Trial name
- NCT03379389
- Testing
- Methenamine + Methylthioninium, Methenamine + Methylthioninium + Acriflavine + Atropa belladona, Antibiotics
- Where
- Brazil
- Volunteers
- 284 people
- Sponsor
- Fundação Educacional Serra dos Órgãos
Urinary Tract Infections, Recurrent UTI
Probiotics and Multi-Drug Resistant Urinary Tract Infection
This pilot study is a single-site randomized, double blinded placebo-controlled in females with recurrent multi-drug resistant (MDR) urinary tract infections(UTI).
- Conditions
- Urinary Tract Infections, Recurrent UTI, Antibiotic Resistant Infection
- Trial name
- NCT03644966
- Testing
- Bifidobacterium infantis, Antibiotics
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Symptomatic Urinary Tract Infection, Spinal Cord Injury
Clinical Value of Homeopathic Prophylaxis of Recurrent Urinary Tract Infections in Persons With Spinal Cord Injury
recurrent symptomatic urinary tracts infections (UTI) in persons with spinal cord injury are a frequent problem, leading to significant morbidity and to a decreased quality of life.
- Trial name
- NCT01477502
- Testing
- individual homeopathic treatment, standard treatment without homeopathy
- Where
- Switzerland
- Volunteers
- 46 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Recurrent UTIs, Cystitis Recurrent
Daily Nitrofurantoin Versus Bladder Fulguration Plus Daily Nitrofurantoin for Women With Recurrent Urinary Tract Infections
The goal of this clinical trial is to learn if the drug Nitrofurantoin (NF) taken as a daily antibiotic, works to treat cystitis compared to electrofulguration (EF) and Nitrofurantoin (NF) daily antibiotic.
- Trial name
- NCT06907199
- Testing
- Electrofulguration (EF), Nitrofurantoin (NF)
- Where
- 2 sites in United States
- Volunteers
- 104 people
- Sponsor
- University of Texas Southwestern Medical Center
Urinary Tract Infections
Fecal Microbiota Transplantation (FMT) for MDRO UTI
The purpose of this study is to determine the safety and impact of fecal microbiota transplantation (FMT) on the fecal and urine microbiome, urine metabolome, risk of recurrent urinary tract infection (UTI), and persistent…
- Trial name
- NCT03367910
- Testing
- Fecal microbiota transplant
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Washington University School of Medicine