Clinical trials: Urinary Tract Infection (UTI)
Recurrent Urinary Tract Infection, Genitourinary Syndrome of Menopause
RCT Comparing Intravaginal Laser Therapy to Sham in Post-menopausal Women with Recurrent Urinary Tract Infections
Recurrent urinary tract infection (rUTI) is a common and difficult to treat problem with limited treatment option; postmenopausal women are disproportionately affected.
- Trial name
- UTIEXTERMINATE (NCT06124820)
- Testing
- Deka SmartXide Touch C60 (MonaLisa Touch)
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- King's College Hospital NHS Trust
Urinary Tract Infections
General Practitioner Reassessment of Urinary Infection Antibiotherapy Prescribed by Emergency Departments
Urinary infections are at the origin of many emergency department consultations and antibiotic prescriptions. Increase of bacteria resistance to antibiotics is promoted by an inappropriate use of those antibiotics but initial…
- Trial name
- ATB-IU (NCT03928951)
- Testing
- General practitioner reassessment of urinary infection antibiotherapy prescribed by emergency departments
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Pyelonephritis
Short-term Antibiotic Therapy for Pyelonephritis in Childhood
The purpose of this study is to evaluate the efficacy of oral ceftibuten for 7 days versus 10 days in acute pyelonephritis in children.
- Trial name
- STUTI (NCT00724256)
- Testing
- ceftibuten
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- IRCCS Burlo Garofolo
Urinary Tract Infections
Diagnostic Tools in Patients With a Suspected Urinary Tract Infection in Primary Care
Background: Inappropriate use of antibiotics is one of the main causes for the increase of antibiotic resistance strains. In Denmark general practice accounts for 90% of all prescribed antibiotics and one of the most common…
- Trial name
- NCT02249273
- Testing
- Diagnostic approaches
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- University of Copenhagen
Severe Complications of Urinary Tract Infections
Complications of UTI in Patients on Dapagliflozin
The objective of this study is to compare, by insulin use at the index date, the sex-specific incidence of hospitalization or emergency department (ED) visit for severe complications of urinary tract infections (UTI), defined as…
- Trial name
- NCT02695173
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 683,380 people
- Sponsor
- AstraZeneca
Infant, Newborn, Infant, Low Birth Weight
Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection
A controlled clinical trial was conducted at eight participating centers between January 1, 1988, and March 31, 1991. Patients were randomly assigned to an intravenous immune globulin group or a control group.
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- IVIG (NCT01203345)
- Testing
- IVIG
- Where
- 8 sites in United States
- Volunteers
- 2,416 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Urinary Tract Infections
The Effect of Sonographic Bladder Compressive Technique for Bag Urine Collection in Pediatrics
Aim: to shorten the time of urination by bladder pressure stimulation in children less than 36 months of age who need urinalysis to exclude or diagnose urinary tract infections and to speed up the start time of antibiotics…
- Trial name
- NCT03152851
- Testing
- Pressure stimulus group
- Where
- 2 sites in South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Urinary Tract Infections
Probiotics as a Prophylactic Aid in Women With Recurrent Urinary Tract Infections (UTI's)
To investigate if administration of probiotics, either orally or vaginally, Can reduce the number of episodes of acute bacterial cystitis and/or Has tolerable adverse effect profile Improves general QoL in these women Improves…
- Trial name
- NCT00781625
- Testing
- UREX-cap-5
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- University Hospital, Akershus
Urinary Tract Infection
Short Course Nitrofurantoin for Acute Cystitis
The purpose of this research study is to determine what the cure rates are with a 5 day course of nitrofurantoin versus the more standard 3 day course of trimethoprim/sulfamethoxazone.
- Trial name
- NCT00391651
- Testing
- Nitrofurantoin 100mg twice daily x 5 days, TMP/SMX DS twice daily x 3 days
- Where
- United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Washington
Complicated Urinary Tract Infection; Cuti
Pharmacokinetics of Benapenem in Subjects With Renal Impairment
This is an open-label, multiple center, parallel-group Study to compare the pharmacokinetics and safety of single-dose benapenem (1.0mg) in subjects with mild or moderate Renal Impairment(RI) and healthy subjects.
- Trial name
- NCT04476407
- Testing
- benapenem
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sihuan Pharmaceutical Holdings Group Ltd.
Urinary Tract Infections, Elderly Infection
Fixed-dose Amikacin for Elderly UTI
Aminoglycosides are broad-spectrum antibiotics, effective against gram-negative bacteria. Aminoglycosides urine concentration exceeds that of the plasma by up to a hundred.
- Trial name
- NCT04197739
- Testing
- Amikacin
- Volunteers
- 200 people
- Sponsor
- Rabin Medical Center
Cystitis, Urinary Tract Infections
Incidence of Cystitis in Women Consuming a Mixture of Cranberry, Cinnamon, Probiotics
Cranberries are traditionally used for urinary comfort and prevention of urinary disorders of bacterial origin and despite an EFSA opinion invalidating the clinical efficacy of cranberries, its mechanism of action has been…
- Trial name
- NCT04987164
- Testing
- Feminabiane CBU
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- CEN Biotech
Urinary Tract Infections
Observational Follow-up Study of REGATTA
Observational follow-up study of patients included in the clinical trial REGATTA.
- Trial name
- REGATTA II (NCT03176563)
- Testing
- Arctuvan, Fosfomycin
- Where
- 47 sites in Germany
- Volunteers
- 398 people
- Sponsor
- University Medical Center Goettingen
Urinary Tract Infections, Urinary Retention Postoperative
Urinary Track Infection Prevention After Urogynecological Surgery
This study is randomized double-blinded placebo-controlled trial to access oral Methenamine Hippurate (MH) in combination with cranberry capsules is superior to cranberry capsules alone in prevention of UTI in patients with…
- Conditions
- Urinary Tract Infections, Urinary Retention Postoperative, Pelvic Organ Prolapse
- Trial name
- NCT03818321
- Testing
- Methenamine Hippurate 1 g tablet
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- TriHealth Inc.
Urinary Tract Infection
Levofloxacin as an Empirical Therapy in Patients With Complicated Urinary Tract Infections
Study is planned to evaluate safety and efficacy of Levolet in patients with complicated UTI
- Trial name
- Levolet-KZ16 (NCT03160807)
- Testing
- Levofloxacin
- Where
- Kazakhstan
- Volunteers
- 214 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Community-Acquired Infections, Respiratory Tract Infections
Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Children in the Paediatric A&E.
Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Acutely Ill Children in a High Prevalent Setting: The Paediatric Accidents \& Emergencies through prospective observational data collection…
- Conditions
- Community-Acquired Infections, Respiratory Tract Infections, Sepsis, Urinary Tract Infections
- Trial name
- ERNIE3 (NCT01396798)
- Where
- Belgium
- Volunteers
- 1,500 people
- Sponsor
- KU Leuven
Bacterial Vaginosis, Candidiasis
Vaginal Ecosystem and Network in the United States Study
The central premise of this study is that the intricate balance and diversity of the vaginal microbiome plays a pivotal role in the onset, progression, and severity of various gynecological conditions.
- Conditions
- Bacterial Vaginosis, Candidiasis, Urinary Tract Infections, Genitourinary Syndrome of Menopause
- Trial name
- VENUS (NCT06472765)
- Testing
- Vaginal Swab Collection
- Where
- 21 sites in United States, Canada
- Volunteers
- 3,250 people, healthy volunteers welcome
- Sponsor
- Vaginal Biome Science
Spinal Cord Injury, Urinary Tract Infection
Effect of Cranberry Capsules on Urinary Infection Rates in Spinal Cord Injured Patients During Post Acute Rehabilitation
The purpose of this study is to establish whether cranberry capsules reduce rates of urinary tract infections during initial rehabilitation immediately after spinal cord injury.
- Conditions
- Spinal Cord Injury, Urinary Tract Infection, Rehabilitation
- Trial name
- NCT01079169
- Testing
- Cranberry capsules
- Where
- Sweden
- Volunteers
- 3 people
- Sponsor
- Uppsala University
Urinary Tract Infections
A Study to Investigate the Efficacy and Safety With Gepotidacin in Japanese Female Participants With Uncomplicated Urinary Tract Infection (Acute Cystitis)
The purpose of this study is to evaluate the consistency of therapeutic response of gepotidacin in female participants with acute uncomplicated cystitis with qualifying bacterial uropathogen(s) at baseline that all are…
- Trial name
- EAGLE-J (NCT05630833)
- Testing
- Gepotidacin, Nitrofurantoin
- Where
- 27 sites in Japan
- Volunteers
- 380 people
- Sponsor
- GlaxoSmithKline
Urinary Tract Infection Chronic
Individualized Homeopathy to Reduce the Use of Antibiotics in Women With Recurrent Uncomplicated Urinary Tract Infections
The aim of the study is to determine the efficacy of individualised homeopathic drug treatment (potency C200 and C1000) compared to placebo in females (age 18<65) with recurrent urinary tract infections, per definition ≥ 2 UTI in…
- Trial name
- iHOM (NCT05545514)
- Testing
- One out of 140 predefined homeopathic medical products (HMP) in potency C200 or C1000,
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- Technical University of Munich